{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T10:59:51Z","timestamp":1775818791954,"version":"3.50.1"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2018,8,16]],"date-time":"2018-08-16T00:00:00Z","timestamp":1534377600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"National Key Research and Development Project of China","award":["2016YFE0205800"],"award-info":[{"award-number":["2016YFE0205800"]}]},{"name":"National Science and Technology Major Project","award":["2016ZX10004222, 2018ZX10733403"],"award-info":[{"award-number":["2016ZX10004222, 2018ZX10733403"]}]},{"name":"National Science and Technology Major Project","award":["2018ZX10713001-010"],"award-info":[{"award-number":["2018ZX10713001-010"]}]},{"name":"Ministry of Science and Technology of China","award":["2015CB910501"],"award-info":[{"award-number":["2015CB910501"]}]},{"DOI":"10.13039\/501100012151","name":"Sanming Project of Medicine in Shenzhen","doi-asserted-by":"crossref","award":["SZSM201412003"],"award-info":[{"award-number":["SZSM201412003"]}],"id":[{"id":"10.13039\/501100012151","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Shenzhen Science and Technology Research and Development Project","award":["JCYJ20160427153238750"],"award-info":[{"award-number":["JCYJ20160427153238750"]}]},{"name":"Shenzhen Science and Technology Research and Development Project","award":["JCYJ20160427151920801"],"award-info":[{"award-number":["JCYJ20160427151920801"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31870163"],"award-info":[{"award-number":["31870163"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Science Foundation of China Innovative Research Group","award":["81621091"],"award-info":[{"award-number":["81621091"]}]},{"name":"National Natural Science Fund for Outstanding Young Scholars","award":["31822055"],"award-info":[{"award-number":["31822055"]}]},{"DOI":"10.13039\/501100004739","name":"Youth Innovation Promotion Association of Chinese Academy of Sciences","doi-asserted-by":"crossref","award":["2017122"],"award-info":[{"award-number":["2017122"]}],"id":[{"id":"10.13039\/501100004739","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,3,19]]},"DOI":"10.1093\/cid\/ciy681","type":"journal-article","created":{"date-parts":[[2018,8,10]],"date-time":"2018-08-10T07:10:18Z","timestamp":1533885018000},"page":"1100-1109","source":"Crossref","is-referenced-by-count":62,"title":["Clinical and Immunological Characteristics of Human Infections With H5N6 Avian Influenza Virus"],"prefix":"10.1093","volume":"68","author":[{"given":"Yuhai","family":"Bi","sequence":"first","affiliation":[{"name":"Key Laboratory of Pathogenic Microbiology and Immunology, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Disease, Institute of Microbiology, Center for Influenza Research and Early Warning, Chinese Academy of Sciences, Beijing"},{"name":"Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen Third People\u2019s Hospital, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuguang","family":"Tan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Pathogenic Microbiology and Immunology, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Disease, Institute of Microbiology, Center for Influenza Research and Early Warning, Chinese Academy of Sciences, Beijing"},{"name":"Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen Third People\u2019s Hospital, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[{"name":"Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen Third People\u2019s Hospital, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary","family":"Wong","sequence":"additional","affiliation":[{"name":"Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen Third People\u2019s Hospital, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Zhao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Pathogenic Microbiology and Immunology, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Disease, Institute of Microbiology, Center for Influenza Research and Early Warning, Chinese Academy of Sciences, Beijing"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingchao","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Tsinghua University, Beijing"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Wang","sequence":"additional","affiliation":[{"name":"Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen Third People\u2019s Hospital, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaonan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Yunnan Center for Disease Control and Prevention, Kunming, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liqiang","family":"Li","sequence":"additional","affiliation":[{"name":"BGI-Shenzhen, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Yuan","sequence":"additional","affiliation":[{"name":"Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen Third People\u2019s Hospital, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Li","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Li","sequence":"additional","affiliation":[{"name":"Yunnan Center for Disease Control and Prevention, Kunming, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Xu","sequence":"additional","affiliation":[{"name":"Yunnan Center for Disease Control and Prevention, Kunming, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weifeng","family":"Shi","sequence":"additional","affiliation":[{"name":"Institute of Pathogen Biology, Taishan Medical College, Taian"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chuansong","family":"Quan","sequence":"additional","affiliation":[{"name":"National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rongrong","family":"Zou","sequence":"additional","affiliation":[{"name":"Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen Third People\u2019s Hospital, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianming","family":"Li","sequence":"additional","affiliation":[{"name":"Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen Third People\u2019s Hospital, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haixia","family":"Zheng","sequence":"additional","affiliation":[{"name":"Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen Third People\u2019s Hospital, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liuqing","family":"Yang","sequence":"additional","affiliation":[{"name":"Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen Third People\u2019s Hospital, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William J","family":"Liu","sequence":"additional","affiliation":[{"name":"National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Di","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Pathogenic Microbiology and Immunology, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Disease, Institute of Microbiology, Center for Influenza Research and Early Warning, Chinese Academy of Sciences, Beijing"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huijun","family":"Wang","sequence":"additional","affiliation":[{"name":"Diqing Tibetan Autonomous Prefecture Centers for Disease Control and Prevention, Shangri-la"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yantao","family":"Qin","sequence":"additional","affiliation":[{"name":"Diqing Tibetan Autonomous Prefecture Centers for Disease Control and Prevention, Shangri-la"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Liu","sequence":"additional","affiliation":[{"name":"Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen Third People\u2019s Hospital, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengyu","family":"Jiang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Tsinghua University, Beijing"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjun","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Pathogenic Microbiology and Immunology, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Disease, Institute of Microbiology, Center for Influenza Research and Early Warning, Chinese Academy of Sciences, Beijing"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Lu","sequence":"additional","affiliation":[{"name":"Yunnan Center for Disease Control and Prevention, Kunming, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George F","family":"Gao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Pathogenic Microbiology and Immunology, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Disease, Institute of Microbiology, Center for Influenza Research and Early Warning, Chinese Academy of Sciences, Beijing"},{"name":"Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen Third People\u2019s Hospital, Shenzhen"},{"name":"National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing"},{"name":"University of Chinese Academy of Sciences Medical School, Beijing, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingxia","family":"Liu","sequence":"additional","affiliation":[{"name":"Shenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen Third People\u2019s Hospital, Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2018,8,16]]},"reference":[{"key":"key\n\t\t\t\t2019031909402106300_CIT0001","author":"World Health Organization","year":"2018"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0002","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1056\/NEJMoa1304459","article-title":"Human infection with a novel avian-origin influenza A (H7N9) virus","volume":"368","author":"Gao","year":"2013","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0003","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1126\/science.1242917","article-title":"Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses","volume":"342","author":"Shi","year":"2013","journal-title":"Science"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0004","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1038\/nature12372","article-title":"Receptor binding by an H7N9 influenza virus from humans","volume":"499","author":"Xiong","year":"2013","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0005","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1126\/science.1243761","article-title":"Preferential recognition of avian-like receptors in human influenza A H7N9 viruses","volume":"342","author":"Xu","year":"2013","journal-title":"Science"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0006","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.jinf.2015.06.009","article-title":"Human infection with a novel, highly pathogenic avian influenza A (H5N6) virus: virological and clinical findings","volume":"72","author":"Pan","year":"2016","journal-title":"J Infect"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0007","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1099\/vir.0.000056","article-title":"Two novel reassortants of avian influenza A (H5N6) virus in China","volume":"96","author":"Bi","year":"2015","journal-title":"J Gen Virol"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0008","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1093\/cid\/cix334","article-title":"Preliminary epidemiologic assessment of human infections with highly pathogenic avian influenza A(H5N6) virus, China","volume":"65","author":"Jiang","year":"2017","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0009","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.chom.2016.10.022","article-title":"Genesis, evolution and prevalence of H5N6 avian influenza viruses in China","volume":"20","author":"Bi","year":"2016","journal-title":"Cell Host Microbe"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0010","doi-asserted-by":"crossref","first-page":"29888","DOI":"10.1038\/srep29888","article-title":"Novel avian influenza A (H5N6) viruses isolated in migratory waterfowl before the first human case reported in China, 2014","volume":"6","author":"Bi","year":"2016","journal-title":"Sci Rep"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0011","doi-asserted-by":"crossref","first-page":"6235","DOI":"10.1128\/JVI.00127-16","article-title":"Highly pathogenic avian influenza H5N6 viruses exhibit enhanced affinity for human type sialic acid receptor and in-contact transmission in model ferrets","volume":"90","author":"Sun","year":"2016","journal-title":"J Virol"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0012","doi-asserted-by":"crossref","first-page":"4655","DOI":"10.1128\/JVI.03095-14","article-title":"A(H7N9) virus results in early induction of proinflammatory cytokine responses in both human lung epithelial and endothelial cells and shows increased human adaptation compared with avian H5N1 virus","volume":"89","author":"Zeng","year":"2015","journal-title":"J Virol"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0013","doi-asserted-by":"crossref","first-page":"10942","DOI":"10.1038\/srep10942","article-title":"The serum profile of hypercytokinemia factors identified in H7N9-infected patients can predict fatal outcomes","volume":"5","author":"Guo","year":"2015","journal-title":"Sci Rep"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0014","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/nature12379","article-title":"Biological features of novel avian influenza A (H7N9) virus","volume":"499","author":"Zhou","year":"2013","journal-title":"Nature"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0015","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.jinf.2016.03.005","article-title":"Emergence of triple-subtype reassortants of fatal human H5N6 avian influenza virus in Yunnan, China","volume":"72","author":"Feng","year":"2016","journal-title":"J Infect"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0016","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1056\/NEJMc1502983","article-title":"Human infection with a novel avian influenza A(H5N6) virus","volume":"373","author":"Yang","year":"2015","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0017","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.meegid.2016.03.010","article-title":"Clinical, epidemiological and virological characteristics of the first detected human case of avian influenza A(H5N6) virus","volume":"40","author":"Zhang","year":"2016","journal-title":"Infect Genet Evol"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0018","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.jinf.2016.02.012","article-title":"Clinical and epidemiological characteristics of a case of avian influenza A H5N6 virus infection","volume":"72","author":"Zhang","year":"2016","journal-title":"J Infect"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0019","doi-asserted-by":"crossref","first-page":"477","DOI":"10.3109\/23744235.2015.1135253","article-title":"Human infection with a highly pathogenic avian influenza A (H5N6) virus in Yunnan province, China","volume":"48","author":"Xu","year":"2016","journal-title":"Infect Dis (Lond)"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0020","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jcv.2016.06.004","article-title":"Clinical and epidemiological characteristics of a patient infected with H5N6 avian influenza A virus","volume":"82","author":"Li","year":"2016","journal-title":"J Clin Virol"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0021","first-page":"1095","article-title":"Comparison of patients hospitalized with influenza A subtypes H7N9, H5N1, and 2009 pandemic H1N1","volume-title":"Clin Infect Dis","author":"Wang","year":"2014"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0022","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/S0140-6736(13)61207-6","article-title":"Human infection with avian influenza A H7N9 virus: an assessment of clinical severity","volume":"382","author":"Yu","year":"2013","journal-title":"Lancet"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0023","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0140-6736(13)61171-X","article-title":"Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases","volume":"382","author":"Cowling","year":"2013","journal-title":"Lancet"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0024","doi-asserted-by":"crossref","first-page":"26624","DOI":"10.1038\/srep26624","article-title":"A new reassortment of influenza A (H7N9) virus causing human infection in Beijing, 2014","volume":"6","author":"Bi","year":"2016","journal-title":"Sci Rep"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0025","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s12985-015-0250-3","article-title":"Detection of highly pathogenic zoonotic influenza virus H5N6 by reverse-transcriptase quantitative polymerase chain reaction","volume":"12","author":"Heine","year":"2015","journal-title":"Virol J"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0026","author":"World Organisation for Animal Health","year":"2018"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0027","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00301-18","article-title":"New threats from H7N9 influenza virus: spread and evolution of high- and low-pathogenicity variants with high genomic diversity in Wave Five","volume":"92","author":"Quan","year":"2018","journal-title":"J Virol"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0028","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1038\/nrmicro3362","article-title":"Enabling the \u2018host jump\u2019: structural determinants of receptor-binding specificity in influenza A viruses","volume":"12","author":"Shi","year":"2014","journal-title":"Nat Rev Microbiol"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0029","doi-asserted-by":"crossref","first-page":"4164","DOI":"10.1073\/pnas.1019109108","article-title":"High genetic compatibility and increased pathogenicity of reassortants derived from avian H9N2 and pandemic H1N1\/2009 influenza viruses","volume":"108","author":"Sun","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0030","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1126\/science.1229455","article-title":"H5N1 hybrid viruses bearing 2009\/H1N1 virus genes transmit in guinea pigs by respiratory droplet","volume":"340","author":"Zhang","year":"2013","journal-title":"Science"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0031","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1146\/annurev-virology-101416-041726","article-title":"Constraints, drivers, and implications of influenza A virus reassortment","volume":"4","author":"Lowen","year":"2017","journal-title":"Annu Rev Virol"},{"issue":"(6)","key":"key\n\t\t\t\t2019031909402106300_CIT0032","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/j.cell.2018.02.025","article-title":"From \u201cA\u201dIV to \u201cZ\u201dIKV: attacks from emerging and re-emerging pathogens","volume":"172","author":"Gao","year":"2018","journal-title":"Cell"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0033","doi-asserted-by":"crossref","first-page":"8671","DOI":"10.1128\/JVI.01034-15","article-title":"Epidemiology, evolution, and recent outbreaks of avian influenza virus in China","volume":"89","author":"Su","year":"2015","journal-title":"J Virol"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0034","doi-asserted-by":"crossref","first-page":"3142","DOI":"10.1038\/ncomms4142","article-title":"Dynamic reassortments and genetic heterogeneity of the human-infecting influenza A (H7N9) virus","volume":"5","author":"Cui","year":"2014","journal-title":"Nat Commun"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0035","article-title":"Genesis and dissemination of highly pathogenic H5N6 avian influenza viruses","volume":"91","author":"Yang","year":"2017","journal-title":"J Virol"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0036","doi-asserted-by":"crossref","first-page":"6833","DOI":"10.1038\/ncomms7833","article-title":"Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8\u207a T cells","volume":"6","author":"Wang","year":"2015","journal-title":"Nat Commun"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0037","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1128\/JVI.02843-13","article-title":"Human cytotoxic T lymphocytes directed to seasonal influenza A viruses cross-react with the newly emerging H7N9 virus","volume":"88","author":"van de Sandt","year":"2014","journal-title":"J Virol"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0038","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1086\/653940","article-title":"Effect of clinical and virological parameters on the level of neutralizing antibody against pandemic influenza A virus H1N1 2009","volume":"51","author":"Hung","year":"2010","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0039","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.chom.2016.05.014","article-title":"Both neutralizing and non-neutralizing human H7N9 influenza vaccine-induced monoclonal antibodies confer protection","volume":"19","author":"Henry Dunand","year":"2016","journal-title":"Cell Host Microbe"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0040","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1086\/594374","article-title":"Broad cross-protection against H5N1 avian influenza virus infection by means of monoclonal antibodies that map to conserved viral epitopes","volume":"199","author":"Chen","year":"2009","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t2019031909402106300_CIT0041","doi-asserted-by":"crossref","first-page":"60","DOI":"10.3389\/fimmu.2016.00060","article-title":"Avian influenza viruses, inflammation, and CD8(+) T cell immunity","volume":"7","author":"Wang","year":"2016","journal-title":"Front Immunol"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cid\/article-pdf\/68\/7\/1100\/28114818\/ciy681.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T23:21:55Z","timestamp":1553037715000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/article\/68\/7\/1100\/5075022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,16]]},"references-count":41,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2018,8,16]]},"published-print":{"date-parts":[[2019,3,19]]}},"URL":"https:\/\/doi.org\/10.1093\/cid\/ciy681","relation":{},"ISSN":["1058-4838","1537-6591"],"issn-type":[{"value":"1058-4838","type":"print"},{"value":"1537-6591","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,4,1]]},"published":{"date-parts":[[2018,8,16]]}}}