{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T23:58:38Z","timestamp":1788479918115,"version":"build-2803163510"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T00:00:00Z","timestamp":1565568000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100006392","name":"AIDS Clinical Trials Group","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006392","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"NIAID","doi-asserted-by":"publisher","award":["U01AI068636"],"award-info":[{"award-number":["U01AI068636"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Statistical and Data Analysis Center","award":["AI-068634"],"award-info":[{"award-number":["AI-068634"]}]},{"DOI":"10.13039\/100000060","name":"NIAID","doi-asserted-by":"publisher","award":["AI069450"],"award-info":[{"award-number":["AI069450"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Durban Adult HIV CRS","award":["5U01AI069426-03"],"award-info":[{"award-number":["5U01AI069426-03"]}]},{"name":"Jabin Sharma","award":["AI069432"],"award-info":[{"award-number":["AI069432"]}]},{"name":"Franklin Kilembe University of North Carolina Project"},{"name":"Kamuzu Central Hospital","award":["AI069518"],"award-info":[{"award-number":["AI069518"]}]},{"name":"Kamuzu Central Hospital","award":["BRS-ACURE-Q-08-00173- TOOI-OOO"],"award-info":[{"award-number":["BRS-ACURE-Q-08-00173- TOOI-OOO"]}]},{"name":"Wits HIV Clinical Research Site","award":["AI069463"],"award-info":[{"award-number":["AI069463"]}]},{"name":"Wits HIV Clinical Research Site","award":["ACURE-Q-07-00143 T006"],"award-info":[{"award-number":["ACURE-Q-07-00143 T006"]}]},{"name":"Daralak Tavornprasit (Research Institute for Health Sciences-Chiang Mai University;","award":["AI069399"],"award-info":[{"award-number":["AI069399"]}]},{"name":"Daralak Tavornprasit (Research Institute for Health Sciences-Chiang Mai University;","award":["AACTG.27.5199.06"],"award-info":[{"award-number":["AACTG.27.5199.06"]}]},{"name":"Hospital Nossa Senhora da Conceicao CRS","award":["5 U01 AI069401)."],"award-info":[{"award-number":["5 U01 AI069401)."]}]},{"name":"Hospital Nossa Senhora da Conceicao CRS","award":["5U01AI069417-03"],"award-info":[{"award-number":["5U01AI069417-03"]}]},{"name":"Ben Kalonga and Henry Chamba","award":["U01A1069518"],"award-info":[{"award-number":["U01A1069518"]}]},{"name":"Ben Kalonga and Henry Chamba","award":["5U01 AI069438-03"],"award-info":[{"award-number":["5U01 AI069438-03"]}]},{"name":"Ben Kalonga and Henry Chamba","award":["BRS- ACURE-Q-07-00141-T001-001"],"award-info":[{"award-number":["BRS- ACURE-Q-07-00141-T001-001"]}]},{"name":"Ben Kalonga and Henry Chamba","award":["AI069438"],"award-info":[{"award-number":["AI069438"]}]},{"name":"Ben Kalonga and Henry Chamba","award":["BRS-ACURE-Q-08-00007-T-002"],"award-info":[{"award-number":["BRS-ACURE-Q-08-00007-T-002"]}]},{"name":"Ben Kalonga and Henry Chamba","award":["5U01AI069417-03"],"award-info":[{"award-number":["5U01AI069417-03"]}]},{"name":"Ben Kalonga and Henry Chamba","award":["5U01AI069417-03"],"award-info":[{"award-number":["5U01AI069417-03"]}]},{"name":"Ben Kalonga and Henry Chamba","award":["1 U01 068634"],"award-info":[{"award-number":["1 U01 068634"]}]},{"name":"Ben Kalonga and Henry Chamba","award":["UM1 AI06948-08"],"award-info":[{"award-number":["UM1 AI06948-08"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Distal sensory peripheral neuropathy (DSPN) is a complication of human immunodeficiency virus (HIV). We estimate DSPN prevalence in 7 resource-limited settings (RLSs) for combination antiretroviral therapy (cART)\u2013naive people living with HIV (PLWH) compared with matched participants not living with HIV and in PLWH virally suppressed on 1 of 3 cART regimens.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>PLWH with a CD4+ count &amp;lt;300 cells\/mm3 underwent standardized neurological examination and functional status assessments before and every 24 weeks after starting cART. Matched individuals not living with HIV underwent the same examinations once.<\/jats:p>\n                    <jats:p>Associations between covariates with DSPN at entry were assessed using the \u03c72 test, and virally suppressed PLWH were assessed using generalized estimating equations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Before initiating cART, 21.3% of PLWH had DSPN compared with 8.5% of people not living with HIV (n = 2400; \u03c72(df = 1) = 96.5; P &amp;lt; .00001). PLWH with DSPN were more likely to report inability to work [\u03c72(df = 1) = 10.6; P = .001] and depression [\u03c72(df = 1) = 8.9; P = .003] than PLWH without DSPN. Overall prevalence of DSPN among those virally suppressed on cART decreased: 20.3%, week 48; 15.3%, week 144; and 10.3%, week 192. Incident DSPN was seen in 127 PLWH. Longitudinally, DSPN was more likely in older individuals (P &amp;lt; .001) and PLWH with less education (P = .03). There was no significant association between cART regimen and DSPN.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Although the prevalence of DSPN decreased following cART initiation in PLWH, further research could identify strategies to prevent or ameliorate residual DSPN after initiating cART in RLSs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/cid\/ciz745","type":"journal-article","created":{"date-parts":[[2019,8,3]],"date-time":"2019-08-03T15:09:08Z","timestamp":1564844948000},"page":"158-165","source":"Crossref","is-referenced-by-count":11,"title":["Distal Sensory Peripheral Neuropathy in Human Immunodeficiency Virus Type 1\u2013Positive Individuals Before and After Antiretroviral Therapy Initiation in Diverse Resource-Limited Settings"],"prefix":"10.1093","volume":"71","author":[{"given":"Alyssa C","family":"Vecchio","sequence":"first","affiliation":[{"name":"Neurological HIV Center, University of North Carolina, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina M","family":"Marra","sequence":"first","affiliation":[{"name":"Department of Neurology, University of Washington, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Schouten","sequence":"first","affiliation":[{"name":"Department of Neurology, University of Washington, Seattle, Washington, USA"},{"name":"Fred Hutchinson Cancer Research Center and University of Washington, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyu","family":"Jiang","sequence":"first","affiliation":[{"name":"Harvard Chan School of Public Health, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnstone","family":"Kumwenda","sequence":"first","affiliation":[{"name":"Queen Elizabeth College of Medicine-Johns Hopkins Project, Blantyre, Malawi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khuanchai","family":"Supparatpinyo","sequence":"first","affiliation":[{"name":"Chiang Mai University, Chiang Mai, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Hakim","sequence":"first","affiliation":[{"name":"Department of Neurology, University of Zimbabwe, Harare, Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ned","family":"Sacktor","sequence":"first","affiliation":[{"name":"Department of Neurology, Johns Hopkins University, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas B","family":"Campbell","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, University of Colorado School of Medicine, Aurora, Colorado, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srikanth","family":"Tripathy","sequence":"first","affiliation":[{"name":"National AIDS Research Institute, Pune, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nagalingeswaran","family":"Kumarasamy","sequence":"first","affiliation":[{"name":"Gaitonde Centre for AIDS Research and Education, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"La Rosa","sequence":"first","affiliation":[{"name":"Asociacion Civil Impacta Salud y Educacion Lima, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Breno","family":"Santos","sequence":"first","affiliation":[{"name":"Hospital Conceicao, Porto Alegre, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus T","family":"Silva","sequence":"first","affiliation":[{"name":"Fiocruz, Rio De Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Kanyama","sequence":"first","affiliation":[{"name":"UNC Project-Malawi, Lilongwe, Malawi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cindy","family":"Firnhaber","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, University of Colorado School of Medicine, Aurora, Colorado, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mina C","family":"Hosseinipour","sequence":"first","affiliation":[{"name":"UNC Project-Malawi, Lilongwe, Malawi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosie","family":"Mngqibisa","sequence":"first","affiliation":[{"name":"Durban International Clinical Research Site, Durban, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin","family":"Hall","sequence":"first","affiliation":[{"name":"Neurological HIV Center, University of North Carolina, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Cinque","sequence":"first","affiliation":[{"name":"Neurovirology Unit, Universita Vita \u2013 Salute San Raffaele, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Robertson","sequence":"first","affiliation":[{"name":"Neurological HIV Center, University of North Carolina, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,8,12]]},"reference":[{"key":"2020062404334588300_CIT0001","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S1474-4422(13)70002-4","article-title":"Manifestations of HIV infection in the peripheral nervous system","volume":"12","author":"Centner","year":"2013","journal-title":"Lancet Neurol"},{"key":"2020062404334588300_CIT0002","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1097\/QAI.0000000000000167","article-title":"Peripheral neuropathy in primary HIV infection associates with systemic and central nervous system immune activation","volume":"66","author":"Wang","year":"2014","journal-title":"J Acquir Immune Defic Syndr"},{"key":"2020062404334588300_CIT0003","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1007\/s11940-017-0472-3","article-title":"Update of HIV-associated sensory neuropathies","volume":"19","author":"Aziz-Donnelly","year":"2017","journal-title":"Curr Treat Options Neurol"},{"key":"2020062404334588300_CIT0004","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1212\/01.wnl.0000218303.48113.5d","article-title":"HIV neuropathy natural history cohort study: assessment measures and risk factors","volume":"66","author":"Simpson","year":"2006","journal-title":"Neurology"},{"key":"2020062404334588300_CIT0005","first-page":"85","article-title":"Assessment of the prevalence of distal symmetrical polyneuropathy and its risk factors among HAART-treated and untreated HIV infected individuals","volume":"48","author":"Shurie","year":"2010","journal-title":"Ethiop Med J"},{"key":"2020062404334588300_CIT0006","doi-asserted-by":"crossref","first-page":"478","DOI":"10.4103\/0028-3886.121912","article-title":"HIV neuropathy in pre-HAART patients and it\u2019s correlation with risk factors in Central India","volume":"61","author":"Dubey","year":"2013","journal-title":"Neurol India"},{"key":"2020062404334588300_CIT0007","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1212\/WNL.52.3.607","article-title":"Plasma viral load and CD4 lymphocytes predict HIV-associated dementia and sensory neuropathy","volume":"52","author":"Childs","year":"1999","journal-title":"Neurology"},{"key":"2020062404334588300_CIT0008","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1001\/archneurol.2010.76","article-title":"Continued high prevalence and adverse clinical impact of human immunodeficiency virus-associated sensory neuropathy in the era of combination antiretroviral therapy: the CHARTER Study","volume":"67","author":"Ellis","year":"2010","journal-title":"Arch Neurol"},{"key":"2020062404334588300_CIT0009","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1097\/QAD.0b013e328345889d","article-title":"Peripheral neuropathy in HIV: prevalence and risk factors","volume":"25","author":"Evans","year":"2011","journal-title":"AIDS"},{"key":"2020062404334588300_CIT0010","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1002\/mus.25990","article-title":"HIV, antiretrovirals, and peripheral neuropathy: a moving target","volume":"57","author":"Kaku","year":"2018","journal-title":"Muscle Nerve"},{"key":"2020062404334588300_CIT0011","first-page":"1397","article-title":"Neurologic complications of human immunodeficiency virus infection","volume":"24","author":"Saylor","year":"2018","journal-title":"Continuum (Minneap Minn)"},{"key":"2020062404334588300_CIT0012","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1212\/01.WNL.0000152981.32057.BB","article-title":"Markers of immune activation and viral load in HIV-associated sensory neuropathy","volume":"64","author":"Schifitto","year":"2005","journal-title":"Neurology"},{"key":"2020062404334588300_CIT0013","first-page":"961510","article-title":"Influence of age and neurotoxic HAART use on frequency of HIV sensory neuropathy","volume":"2012","author":"Oshinaike","year":"2012","journal-title":"AIDS Res Treat"},{"key":"2020062404334588300_CIT0014","doi-asserted-by":"crossref","first-page":"14","DOI":"10.11604\/pamj.2016.25.14.9699","article-title":"Prevalent neuropathy in a cohort of HIV-infected Kenyan sex workers using antiretroviral drugs","volume":"25","author":"Ndakala","year":"2016","journal-title":"Pan Afr Med J"},{"key":"2020062404334588300_CIT0015","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1002\/ana.21484","article-title":"Human immunodeficiency virus protease inhibitors and risk for peripheral neuropathy","volume":"64","author":"Ellis","year":"2008","journal-title":"Ann Neurol"},{"key":"2020062404334588300_CIT0016","doi-asserted-by":"crossref","first-page":"69","DOI":"10.4103\/nnjcr.nnjcr_6_18","article-title":"Clinical pattern of human immunodeficiency virus-associated sensory neuropathy among adults in Kano, northwestern Nigeria","volume":"7","author":"Rabiu","year":"2018","journal-title":"N Niger J Clin Res"},{"key":"2020062404334588300_CIT0017","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/9781118777374.ch6","article-title":"HIV and peripheral neuropathy","author":"Chai","year":"2016","journal-title":"Chronic Pain HIV"},{"key":"2020062404334588300_CIT0018","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1212\/WNL.0000000000004136","article-title":"Peripheral neuropathy in HIV-infected and uninfected patients in Rakai, Uganda","volume":"89","author":"Saylor","year":"2017","journal-title":"Neurology"},{"key":"2020062404334588300_CIT0019","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jns.2018.02.035","article-title":"Factors associated with distal symmetric polyneuropathies in adult Zambians: a cross-sectional, observational study of the role of HIV, non-antiretroviral medication exposures, and nutrition","volume":"388","author":"Kvalsund","year":"2018","journal-title":"J Neurol Sci"},{"key":"2020062404334588300_CIT0020","volume-title":"Global tuberculosis report 2018","year":"2018"},{"key":"2020062404334588300_CIT0021","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.jctube.2015.11.002","article-title":"Peripheral neuropathy in persons with tuberculosis","volume":"2","author":"Mafukidze","year":"2016","journal-title":"J Clin Tuberc Other Mycobact Dis"},{"key":"2020062404334588300_CIT0022","doi-asserted-by":"crossref","first-page":"S313","DOI":"10.1177\/15648265100314S403","article-title":"Role of nutrition in HIV infection: review of evidence for more effective programming in resource-limited settings","volume":"31","author":"de Pee","year":"2010","journal-title":"Food Nutr Bull"},{"key":"2020062404334588300_CIT0023","doi-asserted-by":"crossref","first-page":"106","DOI":"10.4236\/wja.2017.72010","article-title":"HIV-associated polyneuropathy in resource-limited settings: genetic predisposition and vitamin variations","volume":"7","author":"Ndakala","year":"2017","journal-title":"World Journal of AIDS"},{"key":"2020062404334588300_CIT0024","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1080\/09540121.2010.543883","article-title":"Relationship of depression and catastrophizing to pain, disability, and medication adherence in patients with HIV-associated sensory neuropathy","volume":"23","author":"Lucey","year":"2011","journal-title":"AIDS Care"},{"key":"2020062404334588300_CIT0025","first-page":"88","article-title":"Peripheral neuropathy and quality of life of adults living with HIV\/AIDS in the Rulindo district of Rwanda","volume":"9","author":"Biraguma","year":"2012","journal-title":"SAHARA J"},{"key":"2020062404334588300_CIT0026","article-title":"Persisting high prevalence of HIV distal sensory peripheral neuropathy in the era of cART: correlates in the CHARTER study.","author":"Ellis","year":"2009"},{"key":"2020062404334588300_CIT0027","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1007\/s13365-015-0415-2","article-title":"International neurocognitive normative study: neurocognitive comparison data in diverse resource-limited settings: AIDS Clinical Trials Group A5271","volume":"22","author":"Robertson","year":"2016","journal-title":"J Neurovirol"},{"key":"2020062404334588300_CIT0028","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1007\/s13365-011-0044-3","article-title":"A multinational study of neurological performance in antiretroviral therapy-na\u00efve HIV-1-infected persons in diverse resource-constrained settings","volume":"17","author":"Robertson","year":"2011","journal-title":"J Neurovirol"},{"key":"2020062404334588300_CIT0029","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1093\/cid\/cis507","article-title":"Improved neuropsychological and neurological functioning across three antiretroviral regimens in diverse resource-limited settings: AIDS Clinical Trials Group study a5199, the International Neurological Study","volume":"55","author":"Robertson","year":"2012","journal-title":"Clin Infect Dis"},{"key":"2020062404334588300_CIT0030","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1093\/cid\/ciy718","article-title":"HIV-1 and TB co-infection in multinational resource limited settings: increased neurological dysfunction","volume":"68","author":"Robertson","year":"2018","journal-title":"Clin Infect Dis"},{"key":"2020062404334588300_CIT0031","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1212\/WNL.51.6.1678","article-title":"Screening for distal sensory peripheral neuropathy in HIV-infected persons in research and clinical settings","volume":"51","author":"Marra","year":"1998","journal-title":"Neurology"},{"key":"2020062404334588300_CIT0032","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.2522\/ptj.20130337","article-title":"Quality of life and self-reported lower extremity function in adults with HIV-related distal sensory polyneuropathy","volume":"94","author":"Galantino","year":"2014","journal-title":"Phys Ther"},{"key":"2020062404334588300_CIT0033","doi-asserted-by":"crossref","first-page":"782","DOI":"10.4269\/ajtmh.2011.11-0187","article-title":"Neuropsychiatric and socioeconomic status impact antiretroviral adherence and mortality in rural Zambia","volume":"85","author":"Birbeck","year":"2011","journal-title":"Am J Trop Med Hyg"},{"key":"2020062404334588300_CIT0034","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1080\/13550280500384966","article-title":"Clinical validation of the NeuroScreen","volume":"11","author":"Ellis","year":"2005","journal-title":"J Neurovirol"},{"key":"2020062404334588300_CIT0035","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1212\/WNL.0000000000002837","article-title":"Neurologic signs and symptoms frequently manifest in acute HIV infection","volume":"87","author":"Hellmuth","year":"2016","journal-title":"Neurology"}],"container-title":["Clinical Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cid\/advance-article-pdf\/doi\/10.1093\/cid\/ciz745\/30246857\/ciz745.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/cid\/article-pdf\/71\/1\/158\/33422874\/ciz745.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/cid\/article-pdf\/71\/1\/158\/33422874\/ciz745.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,24]],"date-time":"2020-06-24T04:34:18Z","timestamp":1592973258000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cid\/article\/71\/1\/158\/5547098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,12]]},"references-count":35,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,8,12]]},"published-print":{"date-parts":[[2020,6,24]]}},"URL":"https:\/\/doi.org\/10.1093\/cid\/ciz745","relation":{},"ISSN":["1058-4838","1537-6591"],"issn-type":[{"value":"1058-4838","type":"print"},{"value":"1537-6591","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,7,1]]},"published":{"date-parts":[[2019,8,12]]}}}