{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T08:45:35Z","timestamp":1792226735258,"version":"4.4.0"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T00:00:00Z","timestamp":1609372800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Acute kidney injury (AKI) is a common disorder that complicates the hospital course of many patients. AKI is linked with an independent risk of death, hospital length of stay and chronic kidney disease (CKD). Several preoperative predictors are found to be associated with AKI after surgery independent of its origin (cardiac versus non-cardiac). Among these, anaemia has been widely recognized and studied. Anaemia is more common within the surgical population for various reasons (iron deficiency, blood loss, anaemia of chronic disease such as inflammatory state, malignancy or CKD). Both pre- and postoperative anaemia have a deleterious impact on different clinical outcomes including AKI. In this issue, Nishimoto et al. investigated whether AKI could be a risk factor for anaemia (and not the opposite) and whether anaemia could be an independent mediator of mortality after AKI.<\/jats:p>","DOI":"10.1093\/ckj\/sfaa202","type":"journal-article","created":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T03:25:59Z","timestamp":1600226759000},"page":"471-473","source":"Crossref","is-referenced-by-count":14,"title":["Anaemia and acute kidney injury: the tip of the iceberg?"],"prefix":"10.1093","volume":"14","author":[{"given":"Yannis","family":"Lombardi","sequence":"first","affiliation":[{"name":"AURA Paris Plaisance, Dialyse et aph\u00e9r\u00e8se th\u00e9rapeutique, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Ridel","sequence":"additional","affiliation":[{"name":"AURA Paris Plaisance, Dialyse et aph\u00e9r\u00e8se th\u00e9rapeutique, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxime","family":"Touzot","sequence":"additional","affiliation":[{"name":"AURA Paris Plaisance, Dialyse et aph\u00e9r\u00e8se th\u00e9rapeutique, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,12,31]]},"reference":[{"key":"2022030407592259300_sfaa202-B1","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1038\/s41581-018-0052-0","article-title":"Global epidemiology and outcomes of acute kidney injury","volume":"14","author":"Hoste","year":"2018","journal-title":"Nat Rev Nephrol"},{"key":"2022030407592259300_sfaa202-B2","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1097\/SLA.0b013e3181a40a0b","article-title":"Long-term risk of mortality and acute kidney injury during hospitalization after major surgery","volume":"249","author":"Bihorac","year":"2009","journal-title":"Ann Surg"},{"key":"2022030407592259300_sfaa202-B3","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1007\/s00134-015-3934-7","article-title":"Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study","volume":"41","author":"Hoste","year":"2015","journal-title":"Intensive Care Med"},{"key":"2022030407592259300_sfaa202-B4","doi-asserted-by":"crossref","first-page":"3202","DOI":"10.1093\/ndt\/gfr359","article-title":"Early nephrology consultation can have an impact on outcome of acute kidney injury patients","volume":"26","author":"Ponce","year":"2011","journal-title":"Nephrol Dial Transplant"},{"key":"2022030407592259300_sfaa202-B5","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1097\/SLA.0000000000001582","article-title":"Acute and chronic kidney disease and cardiovascular mortality after major surgery","author":"Ozrazgat-Baslanti","year":"2016","journal-title":"Ann Surg"},{"key":"2022030407592259300_sfaa202-B6","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1164\/rccm.201604-0799OC","article-title":"Recovery after acute kidney injury","volume":"195","author":"Kellum","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"2022030407592259300_sfaa202-B7","doi-asserted-by":"crossref","first-page":"19","DOI":"10.2215\/CJN.00240605","article-title":"Acute kidney injury associated with cardiac surgery","volume":"1","author":"Rosner","year":"2006","journal-title":"Clin J Am Soc Nephrol"},{"key":"2022030407592259300_sfaa202-B8","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1161\/CIRCULATIONAHA.108.800011","article-title":"Acute kidney injury is associated with increased long-term mortality after cardiothoracic surgery","volume":"119","author":"Hobson","year":"2009","journal-title":"Circulation"},{"key":"2022030407592259300_sfaa202-B9","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1038\/nrneph.2017.119","article-title":"Cardiac surgery-associated acute kidney injury: risk factors, pathophysiology and treatment","volume":"13","author":"Wang","year":"2017","journal-title":"Nat Rev Nephrol"},{"key":"2022030407592259300_sfaa202-B10","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1038\/sj.ki.5002419","article-title":"Acute kidney injury prediction following elective cardiac surgery: AKICS score","volume":"72","author":"Palomba","year":"2007","journal-title":"Kidney Int"},{"key":"2022030407592259300_sfaa202-B11","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1001\/jama.2016.5828","article-title":"Effect of early vs delayed initiation of renal replacement therapy on mortality in critically ill patients with acute kidney injury: The ELAIN randomized clinical trial","volume":"315","author":"Zarbock","year":"2016","journal-title":"JAMA"},{"key":"2022030407592259300_sfaa202-B12","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1056\/NEJMoa1603017","article-title":"Initiation strategies for renal-replacement therapy in the intensive care unit","volume":"375","author":"Gaudry","year":"2016","journal-title":"N Engl J Med"},{"key":"2022030407592259300_sfaa202-B13","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1002\/bjs.10498","article-title":"Acute kidney injury and mortality 1 year after major non-cardiac surgery","volume":"104","author":"O'Connor","year":"2017","journal-title":"Br J Surg"},{"key":"2022030407592259300_sfaa202-B14","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1002\/bjs.9861","article-title":"Meta-analysis of the association between preoperative anaemia and mortality after surgery","volume":"102","author":"Fowler","year":"2015","journal-title":"Br J Surg"},{"key":"2022030407592259300_sfaa202-B15","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1002\/ccd.25832","article-title":"Impact of pre- and post-procedural anemia on the incidence of acute kidney injury and 1-year mortality in patients undergoing transcatheter aortic valve implantation (from the French Aortic National CoreValve and Edwards 2 [FRANCE 2] Registry)","volume":"85","author":"Arai","year":"2015","journal-title":"Cathet Cardiovasc Intervent"},{"key":"2022030407592259300_sfaa202-B16","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1177\/1538574417697211","article-title":"Impact of preoperative anemia and postoperative hemoglobin drop on the incidence of acute kidney injury and in-hospital mortality in patients with type B acute aortic syndromes undergoing thoracic endovascular aortic repair","volume":"51","author":"Gorla","year":"2017","journal-title":"Vasc Endovasc Surg"},{"key":"2022030407592259300_sfaa202-B17","doi-asserted-by":"crossref","first-page":"221","DOI":"10.5414\/CN107471","article-title":"The impact of anemia on renal recovery and survival in acute kidney injury","volume":"79","author":"Hu","year":"2013","journal-title":"Clin Nephrol"},{"key":"2022030407592259300_sfaa202-B18","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1159\/000452810","article-title":"Anemia and long-term renal prognosis in patients with post-renal acute kidney injury of nonmalignant cause","volume":"135","author":"Sasaki","year":"2017","journal-title":"Nephron"},{"key":"2022030407592259300_sfaa202-B19","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1681\/ASN.2018070757","article-title":"Simple postoperative AKI risk (SPARK) classification before noncardiac surgery: a prediction index development study with external validation","volume":"30","author":"Park","year":"2019","journal-title":"J Am Soc Nephrol"},{"key":"2022030407592259300_sfaa202-B20","volume":"14"},{"key":"2022030407592259300_sfaa202-B21","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1182\/bloodadvances.2018030387","article-title":"Management of cancer-associated anemia with erythropoiesis-stimulating agents: ASCO\/ASH clinical practice guideline update","volume":"3","author":"Bohlius","year":"2019","journal-title":"Blood Adv"}],"container-title":["Clinical Kidney Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ckj\/article-pdf\/14\/2\/471\/42687558\/sfaa202.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ckj\/article-pdf\/14\/2\/471\/42687558\/sfaa202.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T07:59:41Z","timestamp":1646380781000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ckj\/article\/14\/2\/471\/6056638"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,31]]},"references-count":21,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,12,31]]},"published-print":{"date-parts":[[2021,2,16]]}},"URL":"https:\/\/doi.org\/10.1093\/ckj\/sfaa202","relation":{},"ISSN":["2048-8513"],"issn-type":[{"value":"2048-8513","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,2,1]]},"published":{"date-parts":[[2020,12,31]]}}}