{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T01:22:33Z","timestamp":1784337753864,"version":"3.55.0"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2021,3,15]],"date-time":"2021-03-15T00:00:00Z","timestamp":1615766400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI18\/00356"],"award-info":[{"award-number":["PI18\/00356"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002809","name":"Generalitat de Catalunya","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,6,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The relationship between silicon breast implants (SBIs) and autoimmune\/inflammatory syndrome induced by adjuvants (ASIA) has been extensively analysed, with discordant results. We present a 45-year-old woman with confirmed systemic exposure to SBI who developed systemic sclerosis (SSc) followed by anti-neutrophil cytoplasmic antibody anti-myeloperoxidase vasculitis with renopulmonary syndrome. The novelty of our case is, first, confirmation of systemic exposure to SBI and, second, chronologic development of not one, but two severe autoimmune diseases. Controversy may still remain regarding SBIs and ASIA because it is unclear that previous studies confirmed systemic exposure to silicon in their cohort of patients.<\/jats:p>","DOI":"10.1093\/ckj\/sfab058","type":"journal-article","created":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T20:11:17Z","timestamp":1615493477000},"page":"1848-1850","source":"Crossref","is-referenced-by-count":9,"title":["Systemic sclerosis and microscopic polyangiitis after systemic exposure to silicone"],"prefix":"10.1093","volume":"14","author":[{"given":"Claudia","family":"Carrera Mu\u00f1oz","sequence":"first","affiliation":[{"name":"Department of Nephrology, Hospital Universitari Arnau de Vilanova, Lleida, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Gonz\u00e1lez Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hospital Universitari Arnau de Vilanova, Lleida, 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d\u2019Hebron, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,3,15]]},"reference":[{"key":"2021063008553235900_sfab058-B1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.jaut.2010.07.003","article-title":"\u2018ASIA\u2019 \u2013 autoimmune\/inflammatory syndrome induced by adjuvants","volume":"36","author":"Shoenfeld","year":"2011","journal-title":"J Autoimmun"},{"key":"2021063008553235900_sfab058-B2","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1002\/1529-0131(200111)44:11<2477::AID-ART427>3.0.CO;2-Q","article-title":"Do silicone breast implants cause rheumatologic disorders?: A systematic review for a court-appointed National Science Panel","volume":"44","author":"Tugwell","year":"2001","journal-title":"Arthritis Rheum"},{"key":"2021063008553235900_sfab058-B3","doi-asserted-by":"crossref","first-page":"164","DOI":"10.7326\/M15-1169","article-title":"Long-term health 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