{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T03:50:32Z","timestamp":1768017032049,"version":"3.49.0"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T00:00:00Z","timestamp":1632700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Maintenance haemodialysis (MHD) patients have a high risk of initial mortality from coronavirus disease 2019 (COVID-19). However, long-term consequences of this disease in the MHD population are poorly described. We report the clinical presentation, outcome and long-term follow-up of MHD patients affected by COVID-19 in a multicentric cohort from the Paris, France area.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We conducted a retrospective analysis of clinical presentation and long-term follow-up of MHD patients affected by COVID-19 in 19 MHD centres in the Paris, France area.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>In this cohort of 248 patients with an initial mortality rate of 18%, age, comorbidities, dyspnoea and previous immunosuppressive treatment were associated with death at &amp;lt;30 days. Among the 203 surviving patients following the acute phase, long-term follow-up (median 180 days) was available for 189 (93%) patients. Major adverse events occurred in 30 (16%) patients during follow-up, including 12 deaths (6%) after a median of 78 days from onset of symptoms. Overall, cardiovascular events, infections and gastrointestinal bleeding were the main major adverse events. Post-COVID-19 cachexia was observed in 25\/189 (13%) patients. Lower initial albuminaemia was significantly associated with this cachexia. No reinfection with severe acute respiratory syndrome coronavirus 2 was observed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This work demonstrates the long-term consequences of COVID-19 in MHD patients, highlighting both initial and long-term severity of the disease, including severe cachexia.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ckj\/sfab166","type":"journal-article","created":{"date-parts":[[2021,9,23]],"date-time":"2021-09-23T14:34:48Z","timestamp":1632407688000},"page":"262-268","source":"Crossref","is-referenced-by-count":18,"title":["Long-term impact of COVID-19 among maintenance haemodialysis patients"],"prefix":"10.1093","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1656-8007","authenticated-orcid":false,"given":"Sylvain","family":"Chawki","sequence":"first","affiliation":[{"name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale Unit\u00e9 U944, Universit\u00e9 de Paris, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert","family":"Buchard","sequence":"additional","affiliation":[{"name":"BIOS Health, Cambridge, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamza","family":"Sakhi","sequence":"additional","affiliation":[{"name":"Assistance Publique des H\u00f4pitaux de Paris, H\u00f4pitaux Universitaires Henri Mondor, Service de N\u00e9phrologie et Transplantation, Centre de R\u00e9f\u00e9rence Maladie Rare Syndrome N\u00e9phrotique Idiopathique, F\u00e9d\u00e9ration Hospitalo-Universitaire Innovative Therapy for Immune Disorders, Cr\u00e9teil, France"},{"name":"Universit\u00e9 Paris-Est Cr\u00e9teil, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicaleU955, Institut Mondor de Recherche Biom\u00e9dicale, Cr\u00e9teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karim","family":"Dardim","sequence":"additional","affiliation":[{"name":"ALURAD Isle, Isle, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2144-9379","authenticated-orcid":false,"given":"Karim","family":"El Sakhawi","sequence":"additional","affiliation":[{"name":"Assistance Publique des H\u00f4pitaux de Paris, H\u00f4pitaux Universitaires Henri Mondor, Service de N\u00e9phrologie et Transplantation, Centre de R\u00e9f\u00e9rence Maladie Rare Syndrome N\u00e9phrotique Idiopathique, F\u00e9d\u00e9ration Hospitalo-Universitaire Innovative Therapy for Immune Disorders, Cr\u00e9teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mokhtar","family":"Chawki","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis, Clinique Claude Bernard, Ermont, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henri","family":"Boulanger","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis, Clinique de l\u2019Estr\u00e9e, Stains, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomek","family":"Kofman","sequence":"additional","affiliation":[{"name":"ANDRA, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Djamal","family":"Dahmane","sequence":"additional","affiliation":[{"name":"Assistance Publique des H\u00f4pitaux de Paris, H\u00f4pitaux Universitaires Henri Mondor, Service de N\u00e9phrologie et Transplantation, Centre de R\u00e9f\u00e9rence Maladie Rare Syndrome N\u00e9phrotique Idiopathique, F\u00e9d\u00e9ration Hospitalo-Universitaire Innovative Therapy for Immune Disorders, Cr\u00e9teil, France"},{"name":"Universit\u00e9 Paris-Est Cr\u00e9teil, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicaleU955, Institut Mondor de Recherche Biom\u00e9dicale, Cr\u00e9teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Rieu","sequence":"additional","affiliation":[{"name":"Departement of Nephrology and Dialysis, H\u00f4pital Priv\u00e9 Nord Parisien, Sarcelles, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Attaf","sequence":"additional","affiliation":[{"name":"Frensenius, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salima","family":"Ahriz-Saksi","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis, Clinique de l\u2019Estr\u00e9e, Stains, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afshin","family":"Masoumi","sequence":"additional","affiliation":[{"name":"ANDRA, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali Zineddine","family":"Diddaoui","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis, Clinique Claude Bernard, Ermont, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc","family":"Fromentin","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis, Clinique Claude Bernard, Ermont, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Michaut","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis, Clinique Internationale du Parc Monceaux, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachida","family":"Nebbad","sequence":"additional","affiliation":[{"name":"Centre d\u2019Autodialyse le Figuier, Drancy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Fran\u00e7ois","family":"Desassis","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis, Centre Edouard Rist, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurence","family":"Nicolet","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis, Centre Edouard Rist, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Sohier-Attias","sequence":"additional","affiliation":[{"name":"Centre de N\u00e9phrologie SIRTA, Argenteuil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederic","family":"Besson","sequence":"additional","affiliation":[{"name":"Department of Dialysis, Clinique Lambert, La Garenne-Colombes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Remy","family":"Boula","sequence":"additional","affiliation":[{"name":"Department of Dialysis, Clinique Lambert, La Garenne-Colombes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Hafi","sequence":"additional","affiliation":[{"name":"Department of Dialysis, Clinique Lambert, La Garenne-Colombes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abderrahmane","family":"Ghazali","sequence":"additional","affiliation":[{"name":"Department of Dialysis, Groupe Hospitalier Public Sud de l\u2019Oise, Creil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larbi","family":"Lamriben","sequence":"additional","affiliation":[{"name":"Department of Dialysis, Clinique les Martinets, Rueil Malmaison, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adem","family":"Arezki","sequence":"additional","affiliation":[{"name":"Department of Dialysis, Clinique les Martinets, Rueil Malmaison, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Dupuis","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis, American Hospital of Paris, Neuilly-sur-Seine, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamad-Khair","family":"Rifard","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis, Centre Hospitalier des Quatre Villes, Saint Cloud, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominique","family":"Joly","sequence":"additional","affiliation":[{"name":"Department of Adult Nephrology, Assistance Publique des H\u00f4pitaux de Paris, H\u00f4pital Necker-Enfants Malades, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Attias","sequence":"additional","affiliation":[{"name":"Departement of Nephrology and Dialysis, H\u00f4pital Priv\u00e9 Nord Parisien, Sarcelles, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalil","family":"El Karoui","sequence":"additional","affiliation":[{"name":"Assistance Publique des H\u00f4pitaux de Paris, H\u00f4pitaux Universitaires Henri Mondor, Service de N\u00e9phrologie et Transplantation, Centre de R\u00e9f\u00e9rence Maladie Rare Syndrome N\u00e9phrotique Idiopathique, F\u00e9d\u00e9ration Hospitalo-Universitaire Innovative Therapy for Immune Disorders, Cr\u00e9teil, France"},{"name":"Universit\u00e9 Paris-Est Cr\u00e9teil, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicaleU955, Institut Mondor de Recherche Biom\u00e9dicale, Cr\u00e9teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,9,27]]},"reference":[{"key":"2022032516095610900_sfab166-B1","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/S0140-6736(20)30566-3","article-title":"Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study","volume":"395","author":"Zhou","year":"2020","journal-title":"Lancet"},{"key":"2022032516095610900_sfab166-B2","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0140-6736(20)30211-7","article-title":"Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study","volume":"395","author":"Chen","year":"2020","journal-title":"Lancet"},{"key":"2022032516095610900_sfab166-B3","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.kint.2020.04.030","article-title":"A report from the Brescia Renal COVID Task Force on the clinical characteristics and short-term outcome of hemodialysis patients with SARS-CoV-2 infection","volume":"98","author":"Alberici","year":"2020","journal-title":"Kidney Int"},{"key":"2022032516095610900_sfab166-B4","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.kint.2020.04.031","article-title":"COVID-19: clinical course and outcomes of 36 hemodialysis patients in Spain","volume":"98","author":"Goicoechea","year":"2020","journal-title":"Kidney Int"},{"key":"2022032516095610900_sfab166-B5","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1681\/ASN.2020040470","article-title":"Presentation and outcomes of patients with ESKD and COVID-19","volume":"31","author":"Valeri","year":"2020","journal-title":"J Am Soc Nephrol"},{"key":"2022032516095610900_sfab166-B6","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1053\/j.ajkd.2020.03.009","article-title":"COVID-19 in hemodialysis patients: a report of 5 cases","volume":"76","author":"Wang","year":"2020","journal-title":"Am J Kidney Dis"},{"key":"2022032516095610900_sfab166-B7","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S0140-6736(20)32656-8","article-title":"6-month consequences of COVID-19 in patients discharged from hospital: a cohort study","volume":"397","author":"Huang","year":"2021","journal-title":"Lancet"},{"key":"2022032516095610900_sfab166-B8","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S2213-2600(21)00031-X","article-title":"NICE guideline on long COVID","volume":"9","author":"Venkatesan","year":"2021","journal-title":"Lancet Respir Med"},{"key":"2022032516095610900_sfab166-B9","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.clnu.2008.06.013","article-title":"Cachexia: a new definition","volume":"27","author":"Evans","year":"2008","journal-title":"Clin Nutr Edinb Nutr"},{"key":"2022032516095610900_sfab166-B10","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/sj.ki.5002585","article-title":"A proposed nomenclature and diagnostic criteria for protein\u2013energy wasting in acute and chronic kidney disease","volume":"73","author":"Fouque","year":"2008","journal-title":"Kidney Int"},{"key":"2022032516095610900_sfab166-B11","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.2215\/CJN.04160320","article-title":"Clinical features of maintenance hemodialysis patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China","volume":"15","author":"Wu","year":"2020","journal-title":"Clin J Am Soc Nephrol"},{"key":"2022032516095610900_sfab166-B12","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/j.kint.2020.07.010","article-title":"Treatment impact on COVID-19 evolution in hemodialysis patients","volume":"98","author":"Chawki","year":"2020","journal-title":"Kidney Int"},{"key":"2022032516095610900_sfab166-B13","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1681\/ASN.2020111618","article-title":"Kinetics of anti-SARS-CoV-2 IgG antibodies in hemodialysis patients six months after infection","volume":"32","author":"Sakhi","year":"2021","journal-title":"J Am Soc Nephrol"},{"key":"2022032516095610900_sfab166-B14","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1016\/j.kint.2020.07.030","article-title":"Outcomes of patients with end-stage kidney disease hospitalized with COVID-19","volume":"98","author":"Ng","year":"2020","journal-title":"Kidney Int"},{"key":"2022032516095610900_sfab166-B15","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1161\/HYPERTENSIONAHA.120.16314","article-title":"Antihypertensive drugs and COVID-19 risk","volume":"77","author":"Laura","year":"2021","journal-title":"Hypertension"},{"key":"2022032516095610900_sfab166-B16","author":"REIN annual report 2019"},{"key":"2022032516095610900_sfab166-B17","author":"REIN intermediate bulletin 20\/8\/2021"},{"key":"2022032516095610900_sfab166-B18","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S1470-2045(10)70218-7","article-title":"Definition and classification of cancer cachexia: an international consensus","volume":"12","author":"Fearon","year":"2011","journal-title":"Lancet Oncol"}],"container-title":["Clinical Kidney Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ckj\/advance-article-pdf\/doi\/10.1093\/ckj\/sfab166\/40443901\/sfab166.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ckj\/article-pdf\/15\/2\/262\/42974852\/sfab166.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ckj\/article-pdf\/15\/2\/262\/42974852\/sfab166.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T20:36:29Z","timestamp":1648240589000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ckj\/article\/15\/2\/262\/6375943"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,27]]},"references-count":18,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,9,27]]},"published-print":{"date-parts":[[2022,2,4]]}},"URL":"https:\/\/doi.org\/10.1093\/ckj\/sfab166","relation":{},"ISSN":["2048-8505","2048-8513"],"issn-type":[{"value":"2048-8505","type":"print"},{"value":"2048-8513","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,2]]},"published":{"date-parts":[[2021,9,27]]}}}