{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T23:06:21Z","timestamp":1783724781378,"version":"3.55.0"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2022,3,14]],"date-time":"2022-03-14T00:00:00Z","timestamp":1647216000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"ISCIIII-FEDER","award":["PI17\/00257"],"award-info":[{"award-number":["PI17\/00257"]}]},{"name":"ISCIIII-FEDER","award":["PI21\/01292"],"award-info":[{"award-number":["PI21\/01292"]}]},{"name":"ISCIII-RETICS REDinREN","award":["RD16\/0009\/0030"],"award-info":[{"award-number":["RD16\/0009\/0030"]}]},{"name":"RICORS","award":["RD21\/0005\/0016"],"award-info":[{"award-number":["RD21\/0005\/0016"]}]},{"name":"Enfermedad Glomerular Compleja del"},{"name":"Sistema Nacional de Salud"},{"name":"Enfermedades Glomerulares Complejas"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,22]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Novel coronavirus disease infection (coronavirus disease 2019, COVID-19) was declared a global pandemic in March 2020 and since then has become a major public health problem. The prevalence of COVID-19 infection and acute kidney injury (AKI) is variable depending on several factors such as race\/ethnicity and severity of illness. The pathophysiology of renal involvement in COVID-19 infection is not entirely clear, but it could be in part explained by the viral tropism in the kidney parenchyma. AKI in COVID-19 infection can be either by direct invasion of the virus or as a consequence of immunologic response. Diverse studies have focused on the effect of COVID-19 on glomerulonephritis (GN) patients or the \u2018novo\u2019 GN; however, the effect of COVID-19 in acute tubulointerstitial nephritis (ATIN) has been scarcely studied. In this article, we present five cases with different spectrums of COVID-19 infection and ATIN that may suggest that recent diagnosis of ATIN is accompanied by a worse clinical prognosis in comparison with long-term diagnosed ATIN.<\/jats:p>","DOI":"10.1093\/ckj\/sfac079","type":"journal-article","created":{"date-parts":[[2022,3,11]],"date-time":"2022-03-11T20:11:25Z","timestamp":1647029485000},"page":"1698-1704","source":"Crossref","is-referenced-by-count":9,"title":["COVID-19 infection and renal injury: where is the place for acute interstitial nephritis disease?"],"prefix":"10.1093","volume":"15","author":[{"given":"Juan","family":"Le\u00f3n-Rom\u00e1n","sequence":"first","affiliation":[{"name":"Vall d'Hebron University Hospital, Department of Nephrology , Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Agraz","sequence":"additional","affiliation":[{"name":"Vall d'Hebron University Hospital, Department of Nephrology , Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ander","family":"Vergara","sequence":"additional","affiliation":[{"name":"Vall d'Hebron University Hospital, Department of Nephrology , Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Ramos","sequence":"additional","affiliation":[{"name":"Vall d'Hebron University Hospital, Department of Nephrology , Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5983-6863","authenticated-orcid":false,"given":"Nestor","family":"Toapanta","sequence":"additional","affiliation":[{"name":"Vall d'Hebron University Hospital, Department of Nephrology , Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5130-603X","authenticated-orcid":false,"given":"Clara","family":"Garc\u00eda-Carro","sequence":"additional","affiliation":[{"name":"Clinico San Carlos University Hospital, Department of Nephrology , Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandra","family":"Gabald\u00f3n","sequence":"additional","affiliation":[{"name":"Vall d'Hebron University Hospital, Department of Pathology , Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana","family":"Bury","sequence":"additional","affiliation":[{"name":"Vall d'Hebron University Hospital, Department of Nephrology , Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila","family":"Bermejo","sequence":"additional","affiliation":[{"name":"Vall d'Hebron University Hospital, Department of Nephrology , Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oriol","family":"Bestard","sequence":"additional","affiliation":[{"name":"Vall d'Hebron University Hospital, Department of Nephrology , Barcelona, Spain"},{"name":"Nephrology Research Group, Vall d'Hebron Research Institute (VHIR) , Nephrology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Soler","sequence":"additional","affiliation":[{"name":"Vall d'Hebron University Hospital, Department of Nephrology , Barcelona, Spain"},{"name":"Nephrology Research Group, Vall d'Hebron Research Institute (VHIR) , Nephrology"},{"name":"Red de Investigaci\u00f3n Renal (REDINREN), Instituto Carlos IIIFEDER , Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,3,14]]},"reference":[{"key":"2022082216174693300_bib1","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1007\/s40620-020-00789-y","article-title":"COVID-19 and the kidney: what we think we know so far and what we don't","volume":"33","author":"Farouk","year":"2020","journal-title":"J Nephrol"},{"key":"2022082216174693300_bib2","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1053\/j.ajkd.2020.09.002","article-title":"Outcomes among patients hospitalized with COVID-19 and acute kidney injury","volume":"77","author":"Ng","year":"2021","journal-title":"Am J Kidney Dis"},{"key":"2022082216174693300_bib3","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.kint.2020.05.006","article-title":"Acute kidney injury in patients hospitalized with COVID-19","volume":"98","author":"Hirsch","year":"2020","journal-title":"Kidney Int"},{"key":"2022082216174693300_bib4","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1681\/ASN.2020040419","article-title":"COVID-19 and ACE2 in cardiovascular, lung, and kidney working group. 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