{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T02:14:47Z","timestamp":1784945687429,"version":"3.55.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2023,6,17]],"date-time":"2023-06-17T00:00:00Z","timestamp":1686960000000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,9,29]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>About 3% of all pregnancies occur in patients with some degree of chronic kidney disease (CKD) and, in turn, CKD is a risk factor for developing hypertensive disorders of pregnancies (HDP) and unfavorable pregnancy outcomes, at both the maternal and fetal level. CKD is often characterized by proteinuria and proteinuria is a risk factor for HDP. However, even if the positive correlation between proteinuria and unfavorable pregnancy outcomes is well acknowledged, the degree of proteinuria associated with adverse outcomes is still a matter of debate. In this issue of the Journal, Li et\u00a0al. present a retrospective study that shows that &amp;gt;1\u00a0g of proteinuria\/day is associated with worse maternal outcomes while &amp;gt;2\u00a0g\/day with worse fetal ones. This study gives proteinuria thresholds for unfavorable outcomes in pregnant CKD patients, but it should be kept in mind that there is a linear correlation between proteinuria and worse pregnancy outcomes, thus a strict surveillance during the entire gestation should be advised independently of the proteinuria level.<\/jats:p>","DOI":"10.1093\/ckj\/sfad136","type":"journal-article","created":{"date-parts":[[2023,6,17]],"date-time":"2023-06-17T01:55:18Z","timestamp":1686966918000},"page":"1550-1552","source":"Crossref","is-referenced-by-count":5,"title":["Baseline proteinuria level and adverse outcomes in pregnant women with chronic kidney disease: new evidence and a note of caution"],"prefix":"10.1093","volume":"16","author":[{"given":"Delphine","family":"Kervella","sequence":"first","affiliation":[{"name":"Centre Hospitalier Universitaire de Nantes, Nantes Universit\u00e9, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5561-948X","authenticated-orcid":false,"given":"Massimo","family":"Torreggiani","sequence":"additional","affiliation":[{"name":"N\u00e9phrologie et dialyse, Centre Hospitalier Le Mans , 194 Avenue Rubillard, Le Mans , France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,6,16]]},"reference":[{"key":"2023092902523754200_bib1","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/nrneph.2017.187","article-title":"Reproductive health and pregnancy in women with chronic kidney disease","volume":"14","author":"Wiles","year":"2018","journal-title":"Nat Rev Nephrol"},{"key":"2023092902523754200_bib2","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1681\/ASN.2014050459","article-title":"Risk of adverse pregnancy outcomes in women with CKD","volume":"26","author":"Piccoli","year":"2015","journal-title":"J Am 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