{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T05:39:08Z","timestamp":1781588348495,"version":"3.54.5"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T00:00:00Z","timestamp":1730246400000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>While SARS-CoV-2 infection has direct obvious consequences on patients undergoing dialysis, the COVID-19 pandemic also had an indirect impact on health systems. Therefore, we aimed to determine whether the COVID-19 era itself was associated with adverse consequences in the Swiss dialysis population as compared to the pre-COVID-19 era, while accounting for direct impact of SARS-CoV-2 infection.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We retrospectively included all patients recorded in the Swiss dialysis registry from January 2014 to December 2022. The pre-COVID-19 era and the COVID-19 era were defined based on the cut-off date of January 2020. Cox proportional hazard model was used with all-cause mortality as the primary outcome.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The cohort consisted of 7837 patients from 97 dialysis centres. Median age was 68.6 years with 66.1% men. Crude mortality rates were 11.6% (11.0% to 12.2%) and 14.2% (13.4% to 14.9%) person-years for the pre-COVID-19 era and the COVID-19 era, respectively. In multivariable analysis, SARS-CoV-2 infection was associated with an increased risk of mortality (HR 4.26, 95% CI 3.65 to 4.97, P\u00a0&amp;lt;\u00a0.001) while the COVID-19 era itself was not (HR 0.98, 95% CI 0.88 to 1.08, P\u00a0=\u00a0.687).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The COVID-19 era was not associated with an excess of mortality in the Swiss dialysis population as compared to the pre-COVID-19 era when accounting for the direct effect of SARS-CoV-2 infection. This suggests that control measures established during the pandemic did not have a negative impact on dialysis patients at the national level. These results could inform health policy makers in the eventuality of future pandemics.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ckj\/sfae322","type":"journal-article","created":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T10:49:34Z","timestamp":1730285374000},"source":"Crossref","is-referenced-by-count":1,"title":["Mortality associated with the COVID-19 pandemic in the Swiss dialysis population beyond SARS-CoV-2 infection"],"prefix":"10.1093","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3841-3049","authenticated-orcid":false,"given":"David A","family":"Jaques","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Nephology and Hypertension, Geneva University Hospitals , Geneva ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linard","family":"Hoessly","sequence":"additional","affiliation":[{"name":"Department of Circulation, Thorax and Transplantation, Clinic for Transplantation Immunology and Nephrology, Basel University Hospital , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Guidotti","sequence":"additional","affiliation":[{"name":"Institute of Nephrology, City Hospital Zurich , Zurich ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Koller","sequence":"additional","affiliation":[{"name":"Department of Circulation, Thorax and Transplantation, Clinic for Transplantation Immunology and Nephrology, Basel University Hospital , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belen","family":"Ponte","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Nephology and Hypertension, Geneva University Hospitals , Geneva 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