{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T04:40:07Z","timestamp":1780375207234,"version":"3.54.1"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T00:00:00Z","timestamp":1732492800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82202099"],"award-info":[{"award-number":["82202099"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52227814"],"award-info":[{"award-number":["52227814"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009331","name":"Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support","doi-asserted-by":"publisher","award":["ZYLX201824"],"award-info":[{"award-number":["ZYLX201824"]}],"id":[{"id":"10.13039\/501100009331","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009331","name":"Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support","doi-asserted-by":"publisher","award":["ZYLX202101"],"award-info":[{"award-number":["ZYLX202101"]}],"id":[{"id":"10.13039\/501100009331","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009601","name":"Beijing Municipal Administration of Hospitals","doi-asserted-by":"publisher","award":["SML20150101"],"award-info":[{"award-number":["SML20150101"]}],"id":[{"id":"10.13039\/501100009601","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019398","name":"Beijing Friendship Hospital, Capital Medical University","doi-asserted-by":"publisher","award":["YYZZ202129"],"award-info":[{"award-number":["YYZZ202129"]}],"id":[{"id":"10.13039\/501100019398","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019398","name":"Beijing Friendship Hospital, Capital Medical University","doi-asserted-by":"publisher","award":["yyqcjh2023-7"],"award-info":[{"award-number":["yyqcjh2023-7"]}],"id":[{"id":"10.13039\/501100019398","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Training Fund for Open Projects at Clinical Institutes"},{"name":"Departments of Capital Medical University","award":["CCMU2022ZKYXY011"],"award-info":[{"award-number":["CCMU2022ZKYXY011"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Neurovascular coupling (NVC), as indicated by a comprehensive analysis of the amplitude of low-frequency fluctuation (ALFF) and cerebral blood flow (CBF), provides mechanistic insights into neurological disorders. Patients undergoing peritoneal dialysis (PD) and hemodialysis (HD) often face cognitive impairment, the causes of which are not fully understood.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>ALFF was derived from functional magnetic resonance imaging, and CBF was quantified using arterial spin labeling in a cohort comprising 58 patients with PD, 60 patients with HD and 62 healthy controls. Voxel-based global analysis for both ALFF and CBF, alongside region-based analyses of ALFF-CBF coupling coefficients, were conducted. Additionally, the study explored the correlation between clinical laboratory indices and imaging metrics.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Compared with HC, NVC was reduced in the bilateral medial superior frontal gyrus (SFGmed), insula, posterior cingulate cortex (PCC) and caudate (CAU) among dialysis patients. Furthermore, the PD group exhibited lower NVC in the bilateral SFGmed, bilateral PCC and left CAU compared with the HD group. Within the PD group, sodium level was negatively correlated with the ALFF-CBF coupling coefficient in the right insula. Additionally, a positive correlation emerged between the ALFF-CBF coupling coefficient in bilateral SFGmed and the dialysis adequacy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>While Montreal Cognitive Assessment scores did not significantly differ between patients with PD and HD, PD group demonstrated poorer NVC in the bilateral SFGmed, bilateral PCC and left CAU. Sodium level and dialysis adequacy may affect NVC in patients with PD.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ckj\/sfae353","type":"journal-article","created":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T23:17:21Z","timestamp":1732576641000},"source":"Crossref","is-referenced-by-count":2,"title":["Abnormal neurovascular coupling exists in patients with peritoneal dialysis and hemodialysis: evidence from a multi-mode MRI study"],"prefix":"10.1093","volume":"18","author":[{"given":"Xiayan","family":"Yin","sequence":"first","affiliation":[{"name":"Department of Nephrology, Beijing Friendship Hospital, Capital Medical University , Xicheng District, Beijing ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbo","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Beijing Friendship Hospital, Capital Medical University , Xicheng District, Beijing ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijun","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Radiology, Beijing Friendship Hospital, Capital Medical University , Xicheng District, Beijing ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiamin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Beijing Friendship Hospital, Capital Medical University , Xicheng District, Beijing ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiology, Beijing Friendship Hospital, Capital Medical University , Xicheng District, Beijing ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenghan","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Beijing Friendship Hospital, Capital Medical University , Xicheng District, Beijing ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Beijing Friendship Hospital, Capital Medical University , Xicheng District, Beijing ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenchang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Beijing Friendship Hospital, Capital Medical University , Xicheng District, Beijing ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6884-6323","authenticated-orcid":false,"given":"Hao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Beijing Friendship Hospital, Capital Medical University , Xicheng District, Beijing ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weikang","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Beijing Friendship Hospital, Capital Medical University , Xicheng District, Beijing ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,11,25]]},"reference":[{"key":"2025020409400131300_bib1","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1016\/j.mcna.2023.03.003","article-title":"Overview of, and preparations for dialysis","volume":"107","author":"Gondal","year":"2023","journal-title":"Med Clin North Am"},{"key":"2025020409400131300_bib2","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1053\/j.ackd.2011.09.001","article-title":"Peritoneal dialysis versus hemodialysis: risks, benefits, and access issues","volume":"18","author":"Sinnakirouchenan","year":"2011","journal-title":"Adv Chronic Kidney Dis"},{"key":"2025020409400131300_bib3","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1007\/s00330-018-5675-9","article-title":"Decreased cerebral blood flow and improved cognitive function in patients with end-stage renal disease after peritoneal dialysis: an arterial spin-labelling study","volume":"29","author":"Cheng","year":"2019","journal-title":"Eur Radiol"},{"key":"2025020409400131300_bib4","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1186\/s12916-016-0745-9","article-title":"Cognition in chronic kidney disease: a systematic review and meta-analysis","volume":"14","author":"Berger","year":"2016","journal-title":"BMC Med"},{"key":"2025020409400131300_bib5","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1053\/j.ajkd.2010.11.026","article-title":"Cognitive impairment in peritoneal dialysis patients","volume":"57","author":"Kalirao","year":"2011","journal-title":"Am J Kidney Dis"},{"key":"2025020409400131300_bib6","doi-asserted-by":"publisher","first-page":"2181","DOI":"10.2215\/CJN.01960215","article-title":"Frailty and cognitive function in incident hemodialysis patients","volume":"10","author":"McAdams-DeMarco","year":"2015","journal-title":"Clin J Am Soc Nephrol"},{"key":"2025020409400131300_bib7","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1159\/000058418","article-title":"Psychiatric disorders among patients undergoing hemodialysis therapy","volume":"91","author":"Fukunishi","year":"2002","journal-title":"Nephron"},{"issue":"1 Suppl 1","key":"2025020409400131300_bib8","doi-asserted-by":"publisher","first-page":"A5","DOI":"10.1053\/j.ajkd.2004.10.009","article-title":"USRDS 2005 annual data report: Atlas of End stage Renal Disease in the United States","volume":"45","author":"Collins","year":"2005","journal-title":"Am J Kidney Dis"},{"key":"2025020409400131300_bib9","first-page":"768","article-title":"The impact of different renal replacement therapies on cognitive function in ESRD patients","volume":"16","author":"Min","year":"2017","journal-title":"Chin J Blood Purif"},{"key":"2025020409400131300_bib10","first-page":"14","article-title":"Dialysis induced hypotension\u2014a serious clinical problem in renal replacement therapy","volume":"60 Suppl 2","author":"Su\u0142owicz","year":"2007","journal-title":"Med Pregl"},{"key":"2025020409400131300_bib11","doi-asserted-by":"publisher","first-page":"118503","DOI":"10.1016\/j.neuroimage.2021.118503","article-title":"Advances in resting state fMRI acquisitions for functional connectomics","volume":"243","author":"Raimondo","year":"2021","journal-title":"Neuroimage"},{"key":"2025020409400131300_bib12","first-page":"1","article-title":"Correlation between low-frequency amplitude and serum inflammatory factors in resting-state functional magnetic resonance imaging in mild to moderate depression","volume":"18","author":"Yue","year":"2023","journal-title":"J Magn Reson Imaging"},{"key":"2025020409400131300_bib13","doi-asserted-by":"publisher","first-page":"bhad377","DOI":"10.1093\/cercor\/bhad377","article-title":"Comparison of the effects of peritoneal dialysis and hemodialysis on spontaneous brain activity in CKD patients: an rs-fMRI study","volume":"34","author":"Zhang","year":"2024","journal-title":"Cereb Cortex"},{"key":"2025020409400131300_bib14","doi-asserted-by":"publisher","first-page":"e8989","DOI":"10.7717\/peerj.8989","article-title":"Disturbed neurovascular coupling in hemodialysis patients","volume":"8","author":"Jin","year":"2020","journal-title":"PeerJ"},{"key":"2025020409400131300_bib15","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1186\/1471-244X-12-156","article-title":"The Beijing version of the Montreal Cognitive Assessment as a brief screening tool for mild cognitive impairment: a community-based study","volume":"12","author":"Yu","year":"2012","journal-title":"BMC Psychiatry"},{"key":"2025020409400131300_bib16","doi-asserted-by":"publisher","first-page":"e0227073","DOI":"10.1371\/journal.pone.0227073","article-title":"The validation of the Beijing version of the Montreal Cognitive Assessment in Chinese patients undergoing hemodialysis","volume":"15","author":"Tian","year":"2020","journal-title":"PLoS One"},{"key":"2025020409400131300_bib17","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1053\/j.ajkd.2015.07.015","article-title":"KDOQI Clinical Practice Guideline for Hemodialysis Adequacy: 2015 update","volume":"66","year":"2015","journal-title":"Am J Kidney Dis"},{"key":"2025020409400131300_bib18","first-page":"13","article-title":"DPARSF: a MATLAB toolbox for \u201cpipeline\u201d data analysis of resting-State fMRI","volume":"4","author":"Chao-Gan","year":"2010","journal-title":"Front Syst Neurosci"},{"key":"2025020409400131300_bib19","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1002\/mrm.1910350312","article-title":"Movement-related effects in fMRI time-series","volume":"35","author":"Friston","year":"1996","journal-title":"Magn Reson Med"},{"key":"2025020409400131300_bib20","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/B978-0-444-64196-0.00001-7","article-title":"The cingulate cortex in neurologic diseases: history, structure, overview","volume":"166","author":"Vogt","year":"2019","journal-title":"Handb Clin Neurol"},{"key":"2025020409400131300_bib21","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1093\/brain\/awt162","article-title":"The role of the posterior cingulate cortex in cognition and disease","volume":"137","author":"Leech","year":"2014","journal-title":"Brain"},{"key":"2025020409400131300_bib22","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1073\/pnas.98.2.676","article-title":"A default mode of brain function","volume":"98","author":"Raichle","year":"2001","journal-title":"Proc Natl Acad Sci USA"},{"key":"2025020409400131300_bib23","doi-asserted-by":"publisher","first-page":"9673","DOI":"10.1073\/pnas.0504136102","article-title":"The human brain is intrinsically organized into dynamic, anticorrelated functional networks","volume":"102","author":"Fox","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"2025020409400131300_bib24","doi-asserted-by":"publisher","first-page":"9781","DOI":"10.1073\/pnas.0711791105","article-title":"Consistency and functional specialization in the default mode brain network","volume":"105","author":"Harrison","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"key":"2025020409400131300_bib25","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1038\/s41583-022-00661-x","article-title":"A tripartite view of the posterior cingulate cortex","volume":"24","author":"Foster","year":"2023","journal-title":"Nat Rev Neurosci"},{"key":"2025020409400131300_bib26","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1148\/radiol.2015141913","article-title":"Abnormal intrinsic brain activity patterns in patients with end-stage renal disease undergoing peritoneal dialysis: a resting-state functional MR imaging study","volume":"278","author":"Luo","year":"2016","journal-title":"Radiology"},{"key":"2025020409400131300_bib27","doi-asserted-by":"publisher","first-page":"2671","DOI":"10.1152\/jn.1998.80.5.2671","article-title":"Neuronal activity in medial frontal cortex during learning of sequential procedures","volume":"80","author":"Nakamura","year":"1998","journal-title":"J Neurophysiol"},{"key":"2025020409400131300_bib28","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.neuroscience.2011.01.047","article-title":"Intrasurgical mapping of complex motor function in the superior frontal gyrus","volume":"179","author":"Martino","year":"2011","journal-title":"Neuroscience"},{"key":"2025020409400131300_bib29","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1093\/cercor\/6.1.31","article-title":"Evidence for a two-stage model of spatial working memory processing within the lateral frontal cortex: a positron emission tomography study","volume":"6","author":"Owen","year":"1996","journal-title":"Cereb Cortex"},{"key":"2025020409400131300_bib30","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1146\/annurev-neuro-071013-014030","article-title":"The brain's default mode network","volume":"38","author":"Raichle","year":"2015","journal-title":"Annu Rev Neurosci"},{"key":"2025020409400131300_bib31","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1136\/postgradmedj-2019-136732","article-title":"Insula stroke: the weird and the worrisome","volume-title":"Postgrad Med J","author":"Raghu","year":"2019"},{"key":"2025020409400131300_bib32","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1016\/j.clineuro.2005.09.004","article-title":"The insular lobe and brain plasticity: lessons from tumor surgery","volume":"108","author":"Duffau","year":"2006","journal-title":"Clin Neurol Neurosurg"},{"key":"2025020409400131300_bib33","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1111\/j.1468-1331.2011.03473.x","article-title":"Lesions to the posterior insular cortex cause dysarthria","volume":"18","author":"Baier","year":"2011","journal-title":"Eur J Neurol"},{"key":"2025020409400131300_bib34","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.bbr.2008.11.020","article-title":"The role of the basal ganglia in learning and memory: neuropsychological studies","volume":"199","author":"Grahn","year":"2009","journal-title":"Behav Brain Res"},{"key":"2025020409400131300_bib35","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.pscychresns.2010.02.006","article-title":"Caudate nucleus volume in individuals at ultra-high risk of psychosis: a cross-sectional magnetic resonance imaging study","volume":"182","author":"Hannan","year":"2010","journal-title":"Psychiatry Res"},{"key":"2025020409400131300_bib36","doi-asserted-by":"publisher","first-page":"2853","DOI":"10.1523\/JNEUROSCI.4313-04.2005","article-title":"Signaling microdomains regulate inositol 1,4,5-trisphosphate-mediated intracellular calcium transients in cultured neurons","volume":"25","author":"Jacob","year":"2005","journal-title":"J Neurosci"},{"key":"2025020409400131300_bib37","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1016\/j.neuroscience.2009.07.038","article-title":"Reduced caudate nuclei volumes in patients with congenital central hypoventilation syndrome","volume":"163","author":"Kumar","year":"2009","journal-title":"Neuroscience"},{"key":"2025020409400131300_bib38","first-page":"1276","article-title":"Emerging links between cerebral blood flow regulation and cognitive decline: a role for brain microvascular pericytes","volume":"14","author":"You","year":"2023","journal-title":"Aging Dis"},{"key":"2025020409400131300_bib39","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1007\/s11011-016-9829-7","article-title":"Cerebral blood flow changes in hemodialysis and peritoneal dialysis patients: an arterial-spin labeling MR imaging","volume":"31","author":"Jiang","year":"2016","journal-title":"Metab Brain Dis"},{"key":"2025020409400131300_bib40","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1016\/j.neuroimage.2007.11.053","article-title":"Detection of changed regional cerebral blood flow in mild cognitive impairment and early Alzheimer's dementia by perfusion-weighted magnetic resonance imaging","volume":"40","author":"Luckhaus","year":"2008","journal-title":"Neuroimage"},{"key":"2025020409400131300_bib41","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1016\/j.jalz.2017.02.007","article-title":"Capillary dysfunction is associated with symptom severity and neurodegeneration in Alzheimer's disease","volume":"13","author":"Nielsen","year":"2017","journal-title":"Alzheimers Dement"},{"key":"2025020409400131300_bib42","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1177\/0271678X19890931","article-title":"Brain-kidney interaction: renal dysfunction following ischemic stroke","volume":"40","author":"Zhao","year":"2020","journal-title":"J Cereb Blood Flow Metab"},{"key":"2025020409400131300_bib43","doi-asserted-by":"publisher","first-page":"2593","DOI":"10.1177\/0271678X211007960","article-title":"Neurovascular coupling dysfunction in end-stage renal disease patients related to cognitive impairment","volume":"41","author":"Li","year":"2021","journal-title":"J Cereb Blood Flow Metab"},{"key":"2025020409400131300_bib44","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1038\/nn.4489","article-title":"Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain","volume":"20","author":"Kisler","year":"2017","journal-title":"Nat Neurosci"},{"key":"2025020409400131300_bib45","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1186\/s12868-018-0465-5","article-title":"Neurovascular dysfunction in vascular dementia, Alzheimer's and atherosclerosis","volume":"19","author":"Shabir","year":"2018","journal-title":"BMC Neurosci"},{"key":"2025020409400131300_bib46","doi-asserted-by":"publisher","first-page":"3965","DOI":"10.1002\/alz.13088","article-title":"Associations of blood cell indices and anemia with risk of incident dementia: a prospective cohort study of 313,448 participants","volume":"19","author":"Qiang","year":"2023","journal-title":"Alzheimers Dement"},{"key":"2025020409400131300_bib47","doi-asserted-by":"publisher","first-page":"109925","DOI":"10.1016\/j.celrep.2021.109925","article-title":"Inverse neurovascular coupling contributes to positive feedback excitation of vasopressin neurons during a systemic homeostatic challenge","volume":"37","author":"Roy","year":"2021","journal-title":"Cell Rep"},{"key":"2025020409400131300_bib48","doi-asserted-by":"publisher","first-page":"357","DOI":"10.25259\/ijn_378_23","article-title":"Cognitive dysfunction screening in peritoneal dialysis patients: a cross-sectional study","volume":"34","author":"Br\u00e1s","year":"2024","journal-title":"Indian J Nephrol"},{"key":"2025020409400131300_bib49","doi-asserted-by":"publisher","first-page":"1826","DOI":"10.1002\/gps.5198","article-title":"Association of brain white matter lesions and atrophy with cognitive function in chronic kidney disease","volume":"34","author":"Yeh","year":"2019","journal-title":"Int J Geriatr Psychiatry"},{"key":"2025020409400131300_bib50","first-page":"1787","article-title":"The relationship between white matter lesions and cognitive dysfunction","volume":"32","author":"Chao","year":"2012","journal-title":"Chin J Gerontol"}],"container-title":["Clinical Kidney Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ckj\/advance-article-pdf\/doi\/10.1093\/ckj\/sfae353\/60812181\/sfae353.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ckj\/article-pdf\/18\/1\/sfae353\/60812181\/sfae353.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ckj\/article-pdf\/18\/1\/sfae353\/60812181\/sfae353.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T09:40:22Z","timestamp":1738662022000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ckj\/article\/doi\/10.1093\/ckj\/sfae353\/7908525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,25]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1,7]]}},"URL":"https:\/\/doi.org\/10.1093\/ckj\/sfae353","relation":{},"ISSN":["2048-8505","2048-8513"],"issn-type":[{"value":"2048-8505","type":"print"},{"value":"2048-8513","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,1]]},"published":{"date-parts":[[2024,11,25]]},"article-number":"sfae353"}}