{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T01:38:50Z","timestamp":1789004330654,"version":"build-2803163510"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T00:00:00Z","timestamp":1762387200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Humanidades, Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>In patients with incident end-stage kidney disease (ESKD), hyperkalemia (HyperK) is a common indication for initiating kidney replacement therapy (KRT). Hemodialysis (HD) and peritoneal dialysis (PD) both effectively reduce serum potassium, but HD is often considered superior due to its perceived faster efficiency. However, evidence supporting this perception remains limited. We hypothesized that HD and PD would be equally effective for the management of severe HyperK during hospitalization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a prospective cohort study at the Nephrology Department of Hospital Civil de Guadalajara. Consecutive, dialysis-na\u00efve patients hospitalized with ESKD and severe HyperK (serum potassium &amp;gt;6.5\u00a0mEq\/L at admission) between 2022 and 2024 were included. The modality of KRT (HD vs PD) was determined by the treating nephrology team. The primary outcome was the trajectory of serum potassium reduction between groups. Secondary outcomes included daily potassium trajectory, catheter dysfunction, length of stay and mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighty-two patients were included: 34 initiated PD, 37 HD and 11 received conservative management. Baseline demographic and clinical characteristics were similar across groups (P\u00a0&amp;gt;\u00a0.05). Median age was 65\u00a0years [interquartile range (IQR) 53\u201374], with diabetes in 33% and hypertension in 53%. Median admission potassium was 6.99\u00a0mEq\/L (6.7\u20137.6), serum creatinine 15.9\u00a0mg\/dL (11.5\u201323.1) and estimated glomerular filtration rate 2.91\u00a0mL\/min\/1.73 m\u00b2 (1.80\u20134.09). The PD group underwent a mean of 45 (\u00b115) exchanges during hospitalization, and the HD group received 4.6 (\u00b11) sessions. Serum potassium decreased similarly in both groups (P\u00a0&amp;gt;\u00a0.05), with substantial reductions on Day 1 (PD 6.03\u00a0mEq\/L; HD 5.90\u00a0mEq\/L) and stabilization by Day 5 through Day 15. Catheter dysfunction occurred in 11% of patients, with similar rates between groups, hospitalization median was 5\u00a0days (IQR 3\u20138) and 12-month mortality was 26.8%, without differences between modalities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this prospective cohort of ESKD patients with severe HyperK, both PD and HD achieved comparable potassium reduction and clinical outcomes, supporting PD as an effective alternative for urgent-start KRT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ckj\/sfaf343","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T13:02:23Z","timestamp":1762434143000},"source":"Crossref","is-referenced-by-count":3,"title":["Urgent initiation of hemodialysis versus peritoneal dialysis in severe hyperkalemia: a prospective study"],"prefix":"10.1093","volume":"18","author":[{"given":"Luz","family":"Alcantar-Vallin","sequence":"first","affiliation":[{"name":"Hospital Civil de Guadalajara Fray Antonio Alcalde Nephrology Department, , Guadalajara, Jalisco ,","place":["Mexico"]},{"name":"University of Guadalajara Health Sciences Center , Guadalajara, Jalisco ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 J","family":"Zaragoza","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Hospital H+ Queretaro , Queretaro,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco O","family":"Ru\u00edz-Ochoa","sequence":"additional","affiliation":[{"name":"Hospital Civil de Guadalajara Fray Antonio Alcalde Nephrology Department, , Guadalajara, Jalisco ,","place":["Mexico"]},{"name":"University of Guadalajara Health Sciences Center , Guadalajara, Jalisco ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4431-3223","authenticated-orcid":false,"given":"J Emilio","family":"S\u00e1nchez-Alvarez","sequence":"additional","affiliation":[{"name":"Hospital Universitario Central de Asturias , Oviedo ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gael","family":"Ch\u00e1vez-Alonso","sequence":"additional","affiliation":[{"name":"Hospital Civil de Guadalajara Fray Antonio Alcalde Nephrology Department, , Guadalajara, Jalisco ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulene","family":"Navarro-Viramontes","sequence":"additional","affiliation":[{"name":"Hospital Civil de Guadalajara Fray Antonio Alcalde Nephrology Department, , Guadalajara, Jalisco ,","place":["Mexico"]},{"name":"University of Guadalajara Health Sciences Center , Guadalajara, Jalisco ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narda","family":"Ram\u00edrez-Cortes","sequence":"additional","affiliation":[{"name":"Hospital Civil de Guadalajara Fray Antonio Alcalde Nephrology Department, , Guadalajara, Jalisco ,","place":["Mexico"]},{"name":"University of Guadalajara Health Sciences Center , Guadalajara, Jalisco ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando-Cruz","family":"Aragon","sequence":"additional","affiliation":[{"name":"Hospital Civil de Guadalajara Fray Antonio Alcalde Nephrology Department, , Guadalajara, Jalisco ,","place":["Mexico"]},{"name":"University of Guadalajara Health Sciences Center , Guadalajara, Jalisco ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karla Y","family":"Vargas-Langarica","sequence":"additional","affiliation":[{"name":"Hospital Civil de Guadalajara Fray Antonio Alcalde Nephrology Department, , Guadalajara, Jalisco ,","place":["Mexico"]},{"name":"University of Guadalajara Health Sciences Center , Guadalajara, Jalisco ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Navarro-Blackaller","sequence":"additional","affiliation":[{"name":"Hospital Civil de Guadalajara Fray Antonio Alcalde Nephrology Department, , Guadalajara, Jalisco ,","place":["Mexico"]},{"name":"University of Guadalajara Health Sciences Center , Guadalajara, Jalisco ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram\u00f3n","family":"Medina-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Hospital Civil de Guadalajara Fray Antonio Alcalde Nephrology Department, , Guadalajara, Jalisco ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro Mart\u00ednez","family":"Gallardo-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Hospital Civil de Guadalajara Fray Antonio Alcalde Nephrology Department, , Guadalajara, Jalisco ,","place":["Mexico"]},{"name":"University of Guadalajara Health Sciences Center , Guadalajara, Jalisco ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan A","family":"G\u00f3mez-Fregoso","sequence":"additional","affiliation":[{"name":"Hospital Civil de Guadalajara Fray Antonio Alcalde Nephrology Department, , Guadalajara, Jalisco ,","place":["Mexico"]},{"name":"University of Guadalajara Health Sciences Center , Guadalajara, Jalisco ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Mendoza-Gait\u00e1n","sequence":"additional","affiliation":[{"name":"Hospital Civil de Guadalajara Fray Antonio Alcalde Nephrology Department, , Guadalajara, Jalisco ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Garc\u00eda-Garc\u00eda","sequence":"additional","affiliation":[{"name":"University of Guadalajara Health Sciences Center , Guadalajara, Jalisco ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2786-6667","authenticated-orcid":false,"given":"Jonathan S","family":"Ch\u00e1vez-I\u00f1iguez","sequence":"additional","affiliation":[{"name":"Hospital Civil de Guadalajara Fray Antonio Alcalde Nephrology Department, , Guadalajara, Jalisco ,","place":["Mexico"]},{"name":"University of Guadalajara Health Sciences Center , Guadalajara, Jalisco ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,11,6]]},"reference":[{"key":"2025120104015993400_bib1","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1093\/ajh\/hpad094","article-title":"Potassium and hypertension: a state-of-the-art review","volume":"37","author":"Sriperumbuduri","year":"2024","journal-title":"Am J Hypertens"},{"key":"2025120104015993400_bib2","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1016\/j.jash.2017.09.011","article-title":"Potassium homeostasis in health and disease: a scientific workshop cosponsored by the National Kidney Foundation and the American Society of Hypertension","volume":"11","author":"Kovesdy","year":"2017","journal-title":"J Am Soc Hypertens"},{"key":"2025120104015993400_bib3","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1093\/ndt\/gfae056","article-title":"Hyperkalemia treatment standard","volume":"39","author":"Palmer","year":"2024","journal-title":"Nephrol Dial Transplant"},{"key":"2025120104015993400_bib4","doi-asserted-by":"publisher","first-page":"155","DOI":"10.2215\/CJN.09340817","article-title":"Hyperkalemia across the continuum of kidney function","volume":"13","author":"Palmer","year":"2018","journal-title":"Clin J Am Soc Nephrol"},{"key":"2025120104015993400_bib5","doi-asserted-by":"publisher","first-page":"1277","DOI":"10.34067\/KID.0000912022","article-title":"Dual RAAS blockade in CKD: does the hype have teeth?","volume":"3","author":"Ch\u00e1vez-\u00cd\u00f1iguez","year":"2022","journal-title":"Kidney360"},{"key":"2025120104015993400_bib6","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1016\/j.xkme.2020.09.003","article-title":"Clinical and economic burden of hyperkalemia: a nationwide hospital-based cohort study in Japan","volume":"2","author":"Kanda","year":"2020","journal-title":"Kidney Med"},{"key":"2025120104015993400_bib7","doi-asserted-by":"publisher","first-page":"1824","DOI":"10.34067\/KID.0000000000000541","article-title":"Hyperkalemia and risk of CKD progression: a propensity score-matched analysis","volume":"5","author":"Agiro","year":"2024","journal-title":"Kidney360"},{"key":"2025120104015993400_bib8","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1053\/j.ajkd.2023.03.008","article-title":"Serum potassium and risk of death or kidney replacement therapy in older people with CKD stages 4-5: eight-year follow-up","volume":"82","author":"de Rooij","year":"2023","journal-title":"Am J Kidney Dis"},{"key":"2025120104015993400_bib9","doi-asserted-by":"publisher","first-page":"S117","DOI":"10.1016\/j.kint.2023.10.018","article-title":"KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease","volume":"105","author":"Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group","year":"2024","journal-title":"Kidney Int"},{"key":"2025120104015993400_bib10","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1159\/000529588","article-title":"Serum potassium trajectory during acute kidney injury and mortality risk","volume":"147","author":"Ch\u00e1vez-\u00cd\u00f1iguez","year":"2023","journal-title":"Nephron"},{"key":"2025120104015993400_bib11","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.kint.2019.09.018","article-title":"Potassium homeostasis and management of dyskalemia in kidney diseases: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference","volume":"97","author":"Clase","year":"2020","journal-title":"Kidney Int"},{"key":"2025120104015993400_bib12","doi-asserted-by":"publisher","first-page":"1559","DOI":"10.1001\/jama.2024.16338","article-title":"Dialysis for chronic kidney failure: a review","volume":"332","author":"Flythe","year":"2024","journal-title":"JAMA"},{"key":"2025120104015993400_bib13","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1080\/0886022X.2022.2032151","article-title":"Hyperkalemia in chronic peritoneal dialysis patients","volume":"44","author":"Elliott","year":"2022","journal-title":"Ren Fail"},{"key":"2025120104015993400_bib14","first-page":"287","article-title":"Recommendations for the management of hyperkalemia in the emergency department","volume":"34","author":"\u00c1lvarez-Rodr\u00edguez","year":"2022","journal-title":"Emergencias"},{"key":"2025120104015993400_bib15","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.34067\/KID.0000000863","article-title":"Outcomes of initiating peritoneal dialysis versus hemodialysis in severe, symptomatic kidney failure","volume":"6","author":"Garc\u00eda-Garc\u00eda","year":"2025","journal-title":"Kidney360"},{"key":"2025120104015993400_bib16","doi-asserted-by":"publisher","first-page":"1234","DOI":"10.2215\/CJN.01150112","article-title":"Prevalence and factors associated with hyperkalemia in predialysis patients followed in a low-clearance clinic","volume":"7","author":"Sarafidis","year":"2012","journal-title":"Clin J Am Soc Nephrol"},{"key":"2025120104015993400_bib17","doi-asserted-by":"publisher","first-page":"1534","DOI":"10.1093\/ndt\/gfy249","article-title":"Plasma potassium ranges associated with mortality across stages of chronic kidney disease: the Stockholm CREAtinine Measurements (SCREAM) project","volume":"34","author":"Gasparini","year":"2019","journal-title":"Nephrol Dial Transplant"},{"key":"2025120104015993400_bib18","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1053\/j.ajkd.2022.07.004","article-title":"Peritoneal dialysis prescription and adequacy in clinical practice: core curriculum 2023","volume":"81","author":"Auguste","year":"2023","journal-title":"Am J Kidney Dis"},{"key":"2025120104015993400_bib19","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1111\/nep.13909","article-title":"The impact of anatomical variables on haemodialysis tunnelled catheter replacement without fluoroscopy","volume":"26","author":"Maggiani-Aguilera","year":"2021","journal-title":"Nephrology"},{"key":"2025120104015993400_bib20","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1111\/nep.13252","article-title":"Comparison between incremental and thrice-weekly haemodialysis: systematic review and meta-analysis","volume":"24","author":"Liu","year":"2019","journal-title":"Nephrology"},{"key":"2025120104015993400_bib21","doi-asserted-by":"publisher","first-page":"29","DOI":"10.5414\/CN110075","article-title":"Rectus abdominis muscle thickness as a predictor of peritoneal catheter dysfunction in emergency-start peritoneal dialysis patients","volume":"96","author":"Ch\u00e1vez-I\u00f1iguez","year":"2021","journal-title":"Clin Nephrol"},{"key":"2025120104015993400_bib22","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1177\/08968608231209849","article-title":"Relationship between number of daily exchanges at CAPD start with clinical outcomes","volume":"44","author":"Nardelli","year":"2024","journal-title":"Perit Dial Int"},{"key":"2025120104015993400_bib23","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1177\/089686080502500204","article-title":"Peritoneal catheters and exit-site practices toward optimum peritoneal access: a review of current developments","volume":"25","author":"Flanigan","year":"2005","journal-title":"Perit Dial Int"},{"key":"2025120104015993400_bib24","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1016\/j.ijsu.2014.07.013","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"12","author":"on Elm","year":"2014","journal-title":"Int J Surg"},{"key":"2025120104015993400_bib25","doi-asserted-by":"publisher","first-page":"e1001885","DOI":"10.1371\/journal.pmed.1001885","article-title":"The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) statement","volume":"12","author":"Benchimol","year":"2015","journal-title":"PLoS Med"},{"key":"2025120104015993400_bib26","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1177\/08968608241244939","article-title":"Survival, cumulative hospital days and infectious complications in urgent-start PD compared with urgent-start HD","volume":"45","author":"Virtanen","year":"2025","journal-title":"Perit Dial Int"},{"key":"2025120104015993400_bib27","doi-asserted-by":"publisher","first-page":"529","DOI":"10.3747\/pdi.2016.00264","article-title":"Acute peritoneal dialysis in patients with acute kidney injury","volume":"37","author":"Cho","year":"2017","journal-title":"Perit Dial Int"},{"key":"2025120104015993400_bib28","doi-asserted-by":"publisher","first-page":"S87","DOI":"10.1038\/sj.ki.5002608","article-title":"High volume peritoneal dialysis vs daily hemodialysis: a randomized, controlled trial in patients with acute kidney injury","volume":"73","author":"Gabriel","year":"2008","journal-title":"Kidney Int"},{"key":"2025120104015993400_bib29","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1007\/s11255-012-0301-2","article-title":"A randomized clinical trial of high volume peritoneal dialysis versus extended daily hemodialysis for acute kidney injury patients","volume":"45","author":"Ponce","year":"2013","journal-title":"Int Urol Nephrol"},{"key":"2025120104015993400_bib30","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1111\/1744-9987.12660","article-title":"Acute kidney injury in critically ill patients: a prospective randomized study of tidal peritoneal dialysis versus continuous renal replacement therapy","volume":"22","author":"Al-Hwiesh","year":"2018","journal-title":"Ther Apher Dial"},{"key":"2025120104015993400_bib31","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1177\/08968608251344356","article-title":"Peritoneal dialysis in acute kidney injury: your questions answered","volume":"45","author":"Ch\u00e1vez-I\u00f1iguez","year":"2025","journal-title":"Perit Dial Int"},{"key":"2025120104015993400_bib32","doi-asserted-by":"publisher","first-page":"523","DOI":"10.3747\/pdi.2016.00260","article-title":"Intensive versus minimal standard dosage for peritoneal dialysis in acute kidney injury: a randomized pilot study","volume":"37","author":"Parapiboon","year":"2017","journal-title":"Perit Dial Int"},{"key":"2025120104015993400_bib33","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1111\/hdi.12845","article-title":"Hemodialysis treatment in patients with severe electrolyte disorders: management of hyperkalemia and hyponatremia","volume":"24","author":"Pirklbauer","year":"2020","journal-title":"Hemodial Int"},{"key":"2025120104015993400_bib34","doi-asserted-by":"publisher","first-page":"e86750","DOI":"10.1371\/journal.pone.0086750","article-title":"Serum potassium levels and its variability in incident peritoneal dialysis patients: associations with mortality","volume":"9","author":"Xu","year":"2014","journal-title":"PLoS One"},{"key":"2025120104015993400_bib35","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1159\/000502998","article-title":"Racial and ethnic differences in mortality associated with serum potassium in incident peritoneal dialysis patients","volume":"50","author":"Eriguchi","year":"2019","journal-title":"Am J Nephrol"},{"key":"2025120104015993400_bib36","doi-asserted-by":"publisher","first-page":"1699","DOI":"10.34067\/KID.0004752022","article-title":"A nomogram to identify hyperkalemia risk in patients with advanced CKD","volume":"3","author":"Xue","year":"2022","journal-title":"Kidney360"},{"key":"2025120104015993400_bib37","doi-asserted-by":"publisher","first-page":"3155","DOI":"10.1681\/ASN.2016121344","article-title":"How dangerous is hyperkalemia?","volume":"28","author":"Montford","year":"2017","journal-title":"J Am Soc Nephrol"}],"container-title":["Clinical Kidney Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ckj\/advance-article-pdf\/doi\/10.1093\/ckj\/sfaf343\/65236891\/sfaf343.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ckj\/article-pdf\/18\/12\/sfaf343\/65236891\/sfaf343.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ckj\/article-pdf\/18\/12\/sfaf343\/65236891\/sfaf343.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T09:34:56Z","timestamp":1764581696000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ckj\/article\/doi\/10.1093\/ckj\/sfaf343\/8316135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,6]]},"references-count":37,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ckj\/sfaf343","relation":{},"ISSN":["2048-8505","2048-8513"],"issn-type":[{"value":"2048-8505","type":"print"},{"value":"2048-8513","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,12]]},"published":{"date-parts":[[2025,11,6]]},"article-number":"sfaf343"}}