{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T12:01:54Z","timestamp":1768046514658,"version":"3.49.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T00:00:00Z","timestamp":1764720000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The administration of an adequate dialysis dose is a critical aspect for ensuring the effectiveness of hemodialysis (HD) treatment and improving survival. Kt is a key indicator to evaluate the dose, with two targets: based on sex (Kt-Sx) and body surface area (Kt-BSA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study (2022\u201323) was conducted across 15 HD centers analyzed 1829 prevalent patients and 317\u2009842 HD sessions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>It was found that 65.9% met both Kt targets, 21.2% met only Kt-Sx and 12.9% met neither. Failure to meet both of the targets was associated with being male, older age, shorter time on HD, higher comorbidity, low body mass index, use of a catheter, shorter sessions, conventional HD, low flow rates and small membranes. Meeting at least the Kt-Sx target was associated with a 41.6% reduction in 24-month mortality risk, and an even more favorable association was observed when both targets were met, reducing the risk by 61.7%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings highlight the importance of personalizing dialysis considering both sex and BSA, particularly in overweight or obese patients, to improve survival.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ckj\/sfaf369","type":"journal-article","created":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T12:59:19Z","timestamp":1764680359000},"source":"Crossref","is-referenced-by-count":0,"title":["Individualizing Kt by sex and body surface area: implications for survival in hemodialysis patients"],"prefix":"10.1093","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2730-3242","authenticated-orcid":false,"given":"Mar\u00eda Luz","family":"S\u00e1nchez-Tocino","sequence":"first","affiliation":[{"name":"Unidad de Investigaci\u00f3n, Fundaci\u00f3n Renal Espa\u00f1ola , Madrid ,","place":["Spain"]},{"name":"Universidad de Salamanca Departamento de Enfermer\u00eda y Fisioterapia, , Salamanca ,","place":["Spain"]},{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de Salamanca (IBSAL) , Salamanca ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"L\u00f3pez-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Servicio de Hemodi\u00e1lisis, Complejo Hospitalario Universitario A Coru\u00f1a ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Lorena","family":"Iglesias-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Unidad de 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,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8235-1071","authenticated-orcid":false,"given":"David","family":"Hern\u00e1n","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n, Fundaci\u00f3n Renal Espa\u00f1ola , Madrid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6646-5361","authenticated-orcid":false,"given":"Paula","family":"Manso","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n, Fundaci\u00f3n Renal Espa\u00f1ola , Madrid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-7521-2046","authenticated-orcid":false,"given":"Fabiola","family":"Dapena","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n, Fundaci\u00f3n Renal Espa\u00f1ola , Madrid 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