{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T14:58:17Z","timestamp":1762009097948,"version":"build-2065373602"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T00:00:00Z","timestamp":1550534400000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Adenovirus is an important cause of haemorrhagic cystitis in kidney transplant recipients. The optimal treatment for adenovirus-associated haemorrhagic cystitis (AAHC) is unknown. Intravenous cidofovir may be effective, but nephrotoxicity is a major concern. The use of intravesical cidofovir for viral haemorrhagic cystitis has been reported in haematopoietic stem cell transplant recipients and may be associated with a lower risk of nephrotoxicity, but its use has not been reported in kidney transplant recipients. We report the use of intravesical cidofovir for the treatment of AAHC in a kidney transplant recipients, along with a review of the literature.<\/jats:p>","DOI":"10.1093\/ckj\/sfz016","type":"journal-article","created":{"date-parts":[[2019,1,16]],"date-time":"2019-01-16T20:17:27Z","timestamp":1547669847000},"page":"745-747","source":"Crossref","is-referenced-by-count":3,"title":["The use of intravesical cidofovir for the treatment of adenovirus-associated haemorrhagic cystitis in a kidney transplant recipient"],"prefix":"10.1093","volume":"12","author":[{"given":"Quan Yao","family":"Ho","sequence":"first","affiliation":[{"name":"Department of Renal Medicine, Singapore General Hospital, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chieh Suai","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine, Singapore General Hospital, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siew Yee","family":"Thien","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Singapore General Hospital, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terence","family":"Kee","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine, Singapore General Hospital, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maciej Piotr","family":"Chlebicki","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Singapore General Hospital, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,2,18]]},"reference":[{"key":"2019093012015233800_sfz016-B1","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1093\/ndt\/gft036","article-title":"What do we know about adenovirus in renal transplantation?","volume":"28","author":"Florescu","year":"2013","journal-title":"Nephrol Dial Transplant"},{"key":"2019093012015233800_sfz016-B2","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1086\/426594","article-title":"Intravesical instillation of cidofovir in the treatment of hemorrhagic cystitis caused by adenovirus type 11 in a bone marrow transplant recipient","volume":"40","author":"Fanourgiakis","year":"2005","journal-title":"Clin Infect Dis"},{"key":"2019093012015233800_sfz016-B3","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.jiac.2016.01.013","article-title":"Successful treatment with intravesical cidofovir for virus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation: a case report and a review of the literature","volume":"22","author":"Sakurada","year":"2016","journal-title":"J Infect Chemother"},{"key":"2019093012015233800_sfz016-B4","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1093\/jac\/dkv393","article-title":"Pharmacokinetics and safety of intravesicular cidofovir in allogeneic HSCT recipients","volume":"71","author":"Aitken","year":"2016","journal-title":"J Antimicrob Chemother"},{"key":"2019093012015233800_sfz016-B5","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1093\/jpids\/pix011","article-title":"Renal toxicity in pediatric patients receiving cidofovir for the treatment of adenovirus infection","volume":"6","author":"Vora","year":"2017","journal-title":"J Pediatr Infect Dis Soc"},{"key":"2019093012015233800_sfz016-B6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/tid.12914","article-title":"Comparison of intravenous or intravesical cidofovir in the treatment of BK polyomavirus-associated hemorrhagic cystitis following adult allogeneic stem cell transplantation\u2014a systematic review","volume":"20","author":"Schneidewind","year":"2018","journal-title":"Transpl Infect Dis"}],"container-title":["Clinical Kidney Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ckj\/article-pdf\/12\/5\/745\/30087568\/sfz016.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T04:02:19Z","timestamp":1569902539000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ckj\/article\/12\/5\/745\/5333180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,18]]},"references-count":6,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2019,2,18]]},"published-print":{"date-parts":[[2019,10,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ckj\/sfz016","relation":{},"ISSN":["2048-8505","2048-8513"],"issn-type":[{"type":"print","value":"2048-8505"},{"type":"electronic","value":"2048-8513"}],"subject":[],"published-other":{"date-parts":[[2019,10]]},"published":{"date-parts":[[2019,2,18]]}}}