{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T17:13:01Z","timestamp":1793725981704,"version":"4.6.1"},"reference-count":49,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2019,8,4]],"date-time":"2019-08-04T00:00:00Z","timestamp":1564876800000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"DOPPS Programs"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>International variation in anemia assessment and management practices in chronic kidney disease (CKD) is poorly understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a cross-sectional analysis of anemia laboratory monitoring, prevalence and management in the prospective Chronic Kidney Disease Outcomes and Practice Patterns Study (CKDopps). A total of 6766 participants with CKD Stages 3a\u20135ND from nephrology clinics in Brazil, France, Germany and the USA were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among patients with anemia (hemoglobin &amp;lt;12\u2009g\/dL), 36\u201358% in Brazil, the USA and Germany had repeat hemoglobin measured and 40\u201361% had iron indices measured within 3\u2009months of the index hemoglobin measurement. Anemia was more common in the USA and Brazil than in France and Germany across CKD stages. Higher ferritin and lower iron saturation (TSAT) levels were observed with lower hemoglobin levels, and higher ferritin with more advanced CKD. The proportion of anemic patients with ferritin &amp;lt;100\u2009ng\/mL or TSAT &amp;lt;20% ranged from 42% in Brazil to 53% in France and Germany, and of these patients, over 40% in Brazil, Germany and the USA, compared with 27% in France, were treated with oral or intravenous iron within 3\u2009months after hemoglobin measurement. The proportion of patients with hemoglobin &amp;lt;10\u2009g\/dL treated with erythropoiesis-stimulating agents ranged from 28% in the USA to 57% in Germany.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Hemoglobin and iron stores are measured less frequently than per guidelines. Among all regions, there was a substantial proportion of anemic patients with iron deficiency who were not treated with iron, highlighting an area for practice improvement in CKD care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ckj\/sfz091","type":"journal-article","created":{"date-parts":[[2019,7,10]],"date-time":"2019-07-10T23:10:43Z","timestamp":1562800243000},"page":"613-624","source":"Crossref","is-referenced-by-count":121,"title":["Anemia and iron deficiency among chronic kidney disease Stages 3\u20135ND patients in the Chronic Kidney Disease Outcomes and Practice Patterns Study: often unmeasured, variably treated"],"prefix":"10.1093","volume":"13","author":[{"given":"Michelle M Y","family":"Wong","sequence":"first","affiliation":[{"name":"Department of Medicine, University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Tu","sequence":"additional","affiliation":[{"name":"Arbor Research Collaborative for Health, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Li","sequence":"additional","affiliation":[{"name":"School of Public Health, University of Michigan, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel L","family":"Perlman","sequence":"additional","affiliation":[{"name":"Department of Nephrology, University of Michigan, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Pecoits-Filho","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of British Columbia, Vancouver, BC, Canada"},{"name":"School of Medicine, Pontificia Universidade Catolica do Parana, Curitiba, PR, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio A","family":"Lopes","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina da Bahia School of Medicine, Universidade Federal da Bahia, Salvador, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ichiei","family":"Narita","sequence":"additional","affiliation":[{"name":"Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Science, Niigata, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Reichel","sequence":"additional","affiliation":[{"name":"Nephrological Center, Villingen-Schwenningen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friedrich K","family":"Port","sequence":"additional","affiliation":[{"name":"Arbor Research Collaborative for Health, Ann Arbor, MI, USA"},{"name":"Department of Internal Medicine, Michigan Medicine, and Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nidhi","family":"Sukul","sequence":"additional","affiliation":[{"name":"Department of Nephrology, University of Michigan, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedicte","family":"Stengel","sequence":"additional","affiliation":[{"name":"CESP, Center for Research in Epidemiology and Population Health, Univ Paris-Saclay, Univ Paris-Sud, UVSQ, Inserm UMRS 1018, Villejuif, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce M","family":"Robinson","sequence":"additional","affiliation":[{"name":"Arbor Research Collaborative for Health, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziad A","family":"Massy","sequence":"additional","affiliation":[{"name":"CESP, Center for Research in Epidemiology and Population Health, Univ Paris-Saclay, Univ Paris-Sud, UVSQ, Inserm UMRS 1018, Villejuif, France"},{"name":"Division of 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