{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T12:49:32Z","timestamp":1787921372589,"version":"build-2784847793"},"reference-count":65,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2019,11,27]],"date-time":"2019-11-27T00:00:00Z","timestamp":1574812800000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Sudden death is frequent in haemodialysis (HD) patients. Both hyperkalaemia and change of plasma potassium (K) concentrations induced by HD could explain this. The impact of increasing dialysate K by 1\u2009mEq\/L on plasma K concentrations and electrocardiogram (ECG) results before and after HD sessions was studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with pre-dialysis K\u2009&amp;gt;5.5\u2009mEq\/L were excluded. ECG and K measurements were obtained before and after the first session of the week for 2 weeks. Then, K in the dialysate was increased (from 1 or 3 to 2 or 4\u2009mEq\/L, respectively). Blood and ECG measurements were repeated after 2 weeks of this change.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty-seven prevalent HD patients were included. As expected, a significant decrease in K concentrations was observed after the dialysis session, but this decrease was significantly lower after the switch to an increased dialysate K. The pre-dialysis K concentrations were not different after changing, but post-dialysis K concentrations were higher after switching (P\u2009&amp;lt;\u20090.0001), with a lower incidence of post-dialysis hypokalaemia. Regarding ECG, before switching, the QT interval (QT) dispersion increased during the session, whereas no difference was observed after switching. One week after switching, post-dialysis QT dispersion [38 (34\u201342) ms] was lower than post-dialysis QT dispersion 2 weeks and 1 week before switching [42 (38\u201357) ms, P\u2009=\u20090.0004; and 40 (35\u201350) ms, P\u2009=\u20090.0002].<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A simple increase of 1\u2009mEq\/L of K in the dialysate is associated with a lower risk of hypokalaemia and a lower QT dispersion after the dialysis session. Further study is needed to determine if such a strategy is associated with a lower risk of sudden death.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ckj\/sfz157","type":"journal-article","created":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T22:20:25Z","timestamp":1571264425000},"page":"390-397","source":"Crossref","is-referenced-by-count":7,"title":["A simple modification of dialysate potassium: its impact on plasma potassium concentrations and the electrocardiogram"],"prefix":"10.1093","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1480-5761","authenticated-orcid":false,"given":"Pierre","family":"Delanaye","sequence":"first","affiliation":[{"name":"Department of Nephrology, Dialysis, Transplantation, University of Li\u00e8ge (ULg CHU), CHU Sart Tilman, Li\u00e8ge, Belgium"},{"name":"GIGA Cardiovascular Sciences, University of Li\u00e8ge (ULg CHU), CHU Sart Tilman, Li\u00e8ge, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Krzesinski","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Li\u00e8ge (ULg CHU), CHU Sart Tilman, Li\u00e8ge, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard E","family":"Dubois","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Dialysis, Transplantation, University of Li\u00e8ge (ULg CHU), CHU Sart Tilman, Li\u00e8ge, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Delcour","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Li\u00e8ge (ULg CHU), CHU Sart Tilman, Li\u00e8ge, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Robinet","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Li\u00e8ge (ULg CHU), CHU Sart Tilman, Li\u00e8ge, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Piette","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Li\u00e8ge (ULg CHU), CHU Sart Tilman, Li\u00e8ge, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Marie","family":"Krzesinski","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Dialysis, Transplantation, University of Li\u00e8ge (ULg CHU), CHU Sart Tilman, Li\u00e8ge, Belgium"},{"name":"GIGA Cardiovascular Sciences, University of Li\u00e8ge (ULg CHU), CHU Sart Tilman, Li\u00e8ge, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizio","family":"Lancellotti","sequence":"additional","affiliation":[{"name":"GIGA Cardiovascular Sciences, University of Li\u00e8ge (ULg CHU), CHU Sart Tilman, Li\u00e8ge, Belgium"},{"name":"Department of Cardiology, University of Li\u00e8ge (ULg CHU), CHU Sart Tilman, Li\u00e8ge, 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