{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T12:00:47Z","timestamp":1754481647242},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T00:00:00Z","timestamp":1709769600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6,3]]},"DOI":"10.1093\/clinchem\/hvae020","type":"journal-article","created":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T09:07:52Z","timestamp":1707210472000},"page":"789-791","source":"Crossref","is-referenced-by-count":1,"title":["Biological Insights from Cell-Free DNA Methylome Analysis in Preeclampsia"],"prefix":"10.1093","volume":"70","author":[{"given":"Stephanie C Y","family":"Yu","sequence":"first","affiliation":[{"name":"Centre for Novostics, Hong Kong Science Park , Hong Kong SAR , China"},{"name":"Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong , Hong Kong SAR , China"},{"name":"Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong SAR , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y M Dennis","family":"Lo","sequence":"additional","affiliation":[{"name":"Centre for Novostics, Hong Kong Science Park , Hong Kong SAR , China"},{"name":"Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong , Hong Kong SAR , China"},{"name":"Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong SAR , China"},{"name":"State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong SAR , China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,3,7]]},"reference":[{"key":"2024060223530374900_hvae020-B1","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1038\/s41591-023-02510-5","article-title":"Cell-free DNA methylome analysis for early preeclampsia prediction","volume":"29","author":"De Borre","year":"2023","journal-title":"Nat Med"},{"key":"2024060223530374900_hvae020-B2","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1002\/uog.19112","article-title":"Screening for pre-eclampsia by maternal factors and biomarkers at 11\u201313 weeks\u2019 gestation","volume":"52","author":"Tan","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"key":"2024060223530374900_hvae020-B3","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1002\/uog.18993","article-title":"Association between fetal fraction on cell-free DNA testing and first-trimester markers for pre-eclampsia","volume":"52","author":"Rolnik","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"key":"2024060223530374900_hvae020-B4","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2209852119","article-title":"Epigenetic analysis of cell-free DNA by fragmentomic profiling","volume":"119","author":"Zhou","year":"2022","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2024060223530374900_hvae020-B5","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2019768118","article-title":"Genome-wide detection of cytosine methylation by single molecule real-time sequencing","volume":"118","author":"Tse","year":"2021","journal-title":"Proc Natl Acad Sci U S A"}],"container-title":["Clinical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/clinchem\/article-pdf\/70\/6\/789\/58036662\/hvae020.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/clinchem\/article-pdf\/70\/6\/789\/58036662\/hvae020.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,2]],"date-time":"2024-06-02T19:54:08Z","timestamp":1717358048000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/clinchem\/article\/70\/6\/789\/7623684"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,7]]},"references-count":5,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,3,7]]},"published-print":{"date-parts":[[2024,6,3]]}},"URL":"https:\/\/doi.org\/10.1093\/clinchem\/hvae020","relation":{},"ISSN":["0009-9147","1530-8561"],"issn-type":[{"value":"0009-9147","type":"print"},{"value":"1530-8561","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,6]]},"published":{"date-parts":[[2024,3,7]]}}}