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Here, we explored whether two acute exposures (~0.5\u00a0hours or ~72\u00a0hours) to increased CO2 impact acute temperature tolerance limits in a freshwater fish, rainbow trout (Oncorhynchus mykiss). We separated the potential effects of acute high CO2 exposure on critical thermal maximum (CTmax), caused via either respiratory acidosis (reduced internal pH) or O2 supply capacity (aerobic scope), by exposing rainbow trout to ~1\u00a0kPa CO2 (~1% or 10\u2009000 \u03bcatm) in combination with normoxia or hyperoxia (~21 or 42\u00a0kPa O2, respectively). In normoxia, acute exposure to high CO2 caused a large acidosis in trout (blood pH decreased by 0.43\u00a0units), while a combination of hyperoxia and ~1\u00a0kPa CO2 increased the aerobic scope of trout by 28%. Despite large changes in blood pH and aerobic scope between treatments, we observed no impacts on the CTmax of trout. Our results suggest that the mechanisms that determine the maximum temperature tolerance of trout are independent of blood acid\u2013base balance or the capacity to deliver O2 to tissues.<\/jats:p>","DOI":"10.1093\/conphys\/coae026","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T06:22:27Z","timestamp":1718173347000},"source":"Crossref","is-referenced-by-count":4,"title":["Respiratory acidosis and O<b>2<\/b> supply capacity do not affect the acute temperature tolerance of rainbow trout (<i>Oncorhynchus mykiss<\/i>)"],"prefix":"10.1093","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2351-5886","authenticated-orcid":false,"given":"Daniel W","family":"Montgomery","sequence":"first","affiliation":[{"name":"University of Exeter Biosciences, Stocker Road, , Exeter, EX4 4QD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Finlay","sequence":"additional","affiliation":[{"name":"University of Exeter Biosciences, Stocker Road, , Exeter, EX4 4QD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4856-6164","authenticated-orcid":false,"given":"Stephen D","family":"Simpson","sequence":"additional","affiliation":[{"name":"University of Exeter Biosciences, Stocker Road, , Exeter, EX4 4QD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7821-7029","authenticated-orcid":false,"given":"Georg H","family":"Engelhard","sequence":"additional","affiliation":[{"name":"International Marine Climate Change Centre (iMC3), Centre for Environment, Fisheries & Aquaculture Science (Cefas) , Pakefield Road, Lowestoft, NR33 0HT, UK"},{"name":"University of East Anglia School of Environmental Sciences, , Norwich, NR4 7TJ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5321-8108","authenticated-orcid":false,"given":"Silvana N R","family":"Birchenough","sequence":"additional","affiliation":[{"name":"International Marine Climate Change Centre (iMC3), Centre for Environment, Fisheries & Aquaculture Science (Cefas) , Pakefield Road, Lowestoft, NR33 0HT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8832-0065","authenticated-orcid":false,"given":"Rod W","family":"Wilson","sequence":"additional","affiliation":[{"name":"University of Exeter Biosciences, Stocker Road, , Exeter, EX4 4QD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,5,16]]},"reference":[{"key":"2024061206204514500_ref1","doi-asserted-by":"crossref","DOI":"10.1093\/conphys\/coab101","article-title":"An unusually high upper thermal acclimation potential for rainbow trout","volume":"10","author":"Adams","year":"2022","journal-title":"Conserv 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after exhaustive activity in rainbow trout (Salmo gairdneri) and starry flounder (Platichthys stellatus)","volume":"133","author":"Milligan","year":"1987","journal-title":"J Exp Biol"},{"key":"2024061206204514500_ref51","volume-title":"Department of Fisheries, Government of Western Australia Perth","author":"Molony","year":"2001"},{"key":"2024061206204514500_ref52","doi-asserted-by":"crossref","first-page":"jeb242735","DOI":"10.1242\/jeb.242735","article-title":"Rapid blood acid\u2013base regulation by European sea bass (Dicentrarchus labrax) in response to sudden exposure to high environmental CO2","volume":"225","author":"Montgomery","year":"2022","journal-title":"J Exp Biol"},{"key":"2024061206204514500_ref53","doi-asserted-by":"crossref","first-page":"15152","DOI":"10.1038\/s41598-019-51572-4","article-title":"Rising CO2 enhances hypoxia tolerance in a marine fish","volume":"9","author":"Montgomery","year":"2019","journal-title":"Sci 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L","volume":"20","author":"Mustafa","year":"2011","journal-title":"Ecotoxicology"},{"key":"2024061206204514500_ref57","doi-asserted-by":"crossref","first-page":"jeb245210","DOI":"10.1242\/jeb.245210","article-title":"In a marine teleost, the significance of oxygen supply for acute thermal tolerance depends upon the context and the endpoint used","volume":"226","author":"Nati","year":"2023","journal-title":"J Exp Biol"},{"key":"2024061206204514500_ref58","first-page":"10,710","article-title":"Rapid and highly variable warming of lake surface waters around the globe","volume":"42","author":"O\u2019Reilly","year":"2015","journal-title":"Geophys Res Lett"},{"key":"2024061206204514500_ref59","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.jtherbio.2016.04.001","article-title":"Heat stress is associated with disruption of ion balance in the migratory locust, Locusta migratoria","volume":"68","author":"O\u2019Sullivan","year":"2017","journal-title":"J Therm 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and digestive enzyme activity of flatfish larvae in a changing ocean","volume":"10","author":"Pimentel","year":"2015","journal-title":"PloS One"},{"key":"2024061206204514500_ref65","doi-asserted-by":"crossref","first-page":"2685","DOI":"10.1242\/jeb.134585","article-title":"Oxygen- and capacity-limited thermal tolerance: bridging ecology and physiology","volume":"220","author":"P\u00f6rtner","year":"2017","journal-title":"J Exp Biol"},{"key":"2024061206204514500_ref66","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1126\/science.1135471","article-title":"Climate change affects marine fishes through the oxygen limitation of thermal tolerance","volume":"315","author":"P\u00f6rtner","year":"2007","journal-title":"Science"},{"key":"2024061206204514500_ref67","volume-title":"R: A language and environment for statistical computing","author":"R Core 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