{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T09:27:14Z","timestamp":1787650034807,"version":"build-2736575974"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2021,12,29]],"date-time":"2021-12-29T00:00:00Z","timestamp":1640736000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Children\u2019s Hospital of Pittsburgh Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Women with inflammatory bowel diseases (IBDs), such as Crohn\u2019s disease or ulcerative colitis, face several disease-specific concerns related to their reproductive health decisions. This study explored the reproductive health decision-making experiences and preferences of women with IBD to discover ways to improve this aspect of comprehensive care.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We recruited women ages 18\u201344 years with IBD to participate in individual, semistructured interviews exploring their experiences and attitudes toward parenthood, pregnancy, contraception, and family planning care. Two independent coders performed analysis using an inductive and deductive coding approach and identified key themes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Twenty-one women with IBD participated in interviews (average age 24.7\u00a0\u00b1\u00a05.9 years, range 18\u201343 years; average age of diagnosis 14.1\u00a0\u00b1\u00a02.0 years). We identified 4 key themes: (1) Nulliparous women who do not currently desire pregnancy appear to lack reproductive health knowledge; (2) Women with IBD lack clarity regarding the role IBD plays in contraceptive choice; (3) Related to pregnancy, women are concerned about the heredity of IBD, antepartum disease activity, and the safety of their current medications; (4) Women with IBD typically default to their reproductive health provider for reproductive health care and counseling, but they expect their gastroenterologist to initiate relevant reproductive health discussions with them and to provide information in the context of their disease.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Women have concerns about the effects of IBD on pregnancy, parenthood, and contraceptive choice; however, many have had limited or no discussion with their gastroenterologist about the topic.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/crocol\/otab083","type":"journal-article","created":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T20:18:17Z","timestamp":1640290697000},"source":"Crossref","is-referenced-by-count":13,"title":["Exploring Reproductive Health Decision Experiences and Preferences of Women With Pediatric-Onset Inflammatory Bowel Diseases"],"prefix":"10.1093","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2647-7205","authenticated-orcid":false,"given":"Zach","family":"Picciarelli","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Pittsburgh School of Medicine , Pittsburgh, Pennsylvania , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia M","family":"Stransky","sequence":"additional","affiliation":[{"name":"Center for Women\u2019s Health Research and Innovation, University of Pittsburgh , Pittsburgh, Pennsylvania , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary M","family":"Leech","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Geisel School of Medicine at Dartmouth , Hanover, New Hampshire , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1742-936X","authenticated-orcid":false,"given":"Hilary K","family":"Michel","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Nationwide Children\u2019s Hospital and The Ohio State University College of Medicine , Columbus, Ohio , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Department of Medicine, UPMC , Pittsburgh, Pennsylvania , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra C","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Pittsburgh School of Medicine , Pittsburgh, Pennsylvania , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Whitney M","family":"Gray","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Pittsburgh School of Medicine , Pittsburgh, Pennsylvania , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3916-8260","authenticated-orcid":false,"given":"Traci M","family":"Kazmerski","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Pittsburgh School of Medicine , Pittsburgh, Pennsylvania , USA"},{"name":"Center for Women\u2019s Health Research and Innovation, University of Pittsburgh , Pittsburgh, Pennsylvania , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,12,29]]},"reference":[{"issue":"11\u201312","key":"2022111812294194100_CIT0001","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1111\/apt.15019","article-title":"Systematic review: the consequences of psychosocial effects of inflammatory bowel disease on patients\u2019 reproductive health.","volume":"48","author":"Purewal","year":"2018","journal-title":"Aliment Pharmacol Ther."},{"issue":"3","key":"2022111812294194100_CIT0002","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1097\/MEG.0000000000001037","article-title":"Family planning in inflammatory bowel disease: childlessness and disease-related concerns among female patients.","volume":"30","author":"Walldorf","year":"2018","journal-title":"Eur J Gastroenterol Hepatol."},{"key":"2022111812294194100_CIT0003"},{"issue":"4","key":"2022111812294194100_CIT0004","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1053\/j.gastro.2007.07.019","article-title":"Pregnancy outcomes in women with inflammatory bowel disease: a large community-based study from Northern California.","volume":"133","author":"Mahadevan","year":"2007","journal-title":"Gastroenterology."},{"issue":"4","key":"2022111812294194100_CIT0005","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1093\/ibd\/izz037","article-title":"Inflammatory bowel disease in pregnancy clinical care pathway: a report from the American Gastroenterological Association IBD Parenthood Project Working Group.","volume":"25","author":"Mahadevan","year":"2019","journal-title":"Inflamm Bowel Dis."},{"issue":"12","key":"2022111812294194100_CIT0006","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1002\/ibd.20532","article-title":"Management of the pregnant IBD patient.","volume":"14","author":"Dubinsky","year":"2008","journal-title":"Inflamm Bowel Dis."},{"issue":"2","key":"2022111812294194100_CIT0007","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.gtc.2016.02.006","article-title":"Pregnancy and the patient with inflammatory bowel disease: fertility, treatment, delivery, and complications.","volume":"45","author":"McConnell","year":"2016","journal-title":"Gastroenterol Clin North Am."},{"issue":"10","key":"2022111812294194100_CIT0008","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1093\/ibd\/izz025","article-title":"Contraception, venous thromboembolism, and inflammatory bowel disease: what clinicians (and patients) should know.","volume":"25","author":"Limdi","year":"2019","journal-title":"Inflamm Bowel Dis."},{"issue":"9715","key":"2022111812294194100_CIT0009","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0140-6736(09)61963-2","article-title":"Venous thromboembolism during active disease and remission in inflammatory bowel disease: a cohort study.","volume":"375","author":"Grainge","year":"2010","journal-title":"Lancet."},{"key":"2022111812294194100_CIT0010","volume-title":"Dedoose [Computer Program]. Version 9.0","year":"2017"},{"key":"2022111812294194100_CIT0011","volume-title":"Doing Qualitative Research","author":"Crabtree","year":"1999"},{"key":"2022111812294194100_CIT0012","volume-title":"The Coding Manual for Qualitative Researchers","author":"Saldana","year":"2016","edition":"2"},{"key":"2022111812294194100_CIT0013","author":"United Kingdom National Health Service."},{"issue":"2","key":"2022111812294194100_CIT0014","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1155\/2015\/715354","article-title":"Does the level of reproductive knowledge specific to inflammatory bowel disease predict childlessness among women with inflammatory bowel disease?","volume":"29","author":"Huang","year":"2015","journal-title":"Can J Gastroenterol Hepatol."},{"issue":"2","key":"2022111812294194100_CIT0015","doi-asserted-by":"crossref","DOI":"10.1002\/pbc.26829","article-title":"Desire for parenthood and reproductive health knowledge in adolescents and young adults with sickle cell disease and their caregivers.","volume":"65","author":"Nahata","year":"2018","journal-title":"Pediatr Blood Cancer"},{"issue":"1","key":"2022111812294194100_CIT0016","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/1054-139X(94)00096-W","article-title":"Reproductive health in young women with cystic fibrosis: knowledge, behavior and attitudes.","volume":"17","author":"Sawyer","year":"1995","journal-title":"J Adolesc Health."},{"issue":"3","key":"2022111812294194100_CIT0017","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1111\/j.1743-6109.2008.01049.x","article-title":"Sexual and reproductive health knowledge in cystic fibrosis female patients and their parents.","volume":"6","author":"Korzeniewska","year":"2009","journal-title":"J Sex Med."},{"issue":"1","key":"2022111812294194100_CIT0018","doi-asserted-by":"crossref","first-page":"e000071","DOI":"10.1136\/bmjgast-2015-000071","article-title":"Effectiveness of disease-specific cognitive-behavioural therapy on depression, anxiety, quality of life and the clinical course of disease in adolescents with inflammatory bowel disease: study protocol of a multicentre randomised controlled trial (HAPPY-IBD).","volume":"3","author":"van den Brink","year":"2016","journal-title":"BMJ Open Gastroenterol."},{"issue":"2","key":"2022111812294194100_CIT0019","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s11136-020-02653-9","article-title":"Depression, anxiety, and loneliness among adolescents and young adults with IBD in the UK: the role of disease severity, age of onset, and embarrassment of the condition.","volume":"30","author":"Qualter","year":"2021","journal-title":"Qual Life Res."},{"issue":"1","key":"2022111812294194100_CIT0020","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/s12969-020-00460-7","article-title":"Reproductive health needs of adolescent and young adult women with pediatric rheumatic diseases.","volume":"18","author":"Carandang","year":"2020","journal-title":"Pediatr Rheumatol Online J."},{"issue":"1","key":"2022111812294194100_CIT0021","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.contraception.2020.10.004","article-title":"Exploring the reproductive decision support needs and preferences of women with cystic fibrosis.","volume":"103","author":"Leech","year":"2021","journal-title":"Contraception."},{"issue":"8","key":"2022111812294194100_CIT0022","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1002\/ppul.24015","article-title":"Perspectives of adolescent girls with cystic fibrosis and parents on disease-specific sexual and reproductive health education.","volume":"53","author":"Kazmerski","year":"2018","journal-title":"Pediatr Pulmonol."},{"key":"2022111812294194100_CIT0023","doi-asserted-by":"crossref","first-page":"551","DOI":"10.3389\/fimmu.2015.00551","article-title":"Inflammatory bowel disease: genetics, epigenetics, and pathogenesis.","volume":"6","author":"Loddo","year":"2015","journal-title":"Front Immunol."},{"issue":"6","key":"2022111812294194100_CIT0024","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1093\/ibd\/izy085","article-title":"Determinants of IBD heritability: genes, bugs, and more.","volume":"24","author":"Turpin","year":"2018","journal-title":"Inflamm Bowel Dis."},{"issue":"6","key":"2022111812294194100_CIT0025","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.cgh.2010.02.014","article-title":"Crohn\u2019s disease is a risk factor for preterm birth.","volume":"8","author":"Stephansson","year":"2010","journal-title":"Clin Gastroenterol Hepatol."},{"issue":"3","key":"2022111812294194100_CIT0026","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1002\/ibd.21369","article-title":"Congenital abnormalities and other birth outcomes in children born to women with ulcerative colitis in Denmark and Sweden.","volume":"17","author":"Stephansson","year":"2011","journal-title":"Inflamm Bowel Dis."},{"issue":"11","key":"2022111812294194100_CIT0027","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.3109\/00365521.2010.503967","article-title":"Pregnancy outcome in patients with inflammatory bowel disease according to the activity of the disease and the medical treatment: a case-control study.","volume":"45","author":"Moln\u00e1r","year":"2010","journal-title":"Scand J Gastroenterol."},{"issue":"36","key":"2022111812294194100_CIT0028","first-page":"1595","article-title":"Crohn\u2019s disease as a risk factor for the outcome of pregnancy.","volume":"47","author":"Morales","year":"2000","journal-title":"Hepatogastroenterology."},{"issue":"6","key":"2022111812294194100_CIT0029","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1080\/00365521.1984.12005800","article-title":"Pregnancy in Crohn\u2019s disease.","volume":"19","author":"Nielsen","year":"1984","journal-title":"Scand J Gastroenterol."},{"issue":"4","key":"2022111812294194100_CIT0030","first-page":"265","article-title":"The course of inflammatory bowel disease during pregnancy and postpartum.","volume":"75","author":"Mogadam","year":"1981","journal-title":"Am J Gastroenterol."},{"issue":"4","key":"2022111812294194100_CIT0031","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1177\/014107688607900410","article-title":"Inflammatory bowel disease in pregnancy: a review.","volume":"79","author":"Miller","year":"1986","journal-title":"J R Soc Med."},{"issue":"2","key":"2022111812294194100_CIT0032","first-page":"96","article-title":"Pregnancy and inflammatory bowel disease.","volume":"11","author":"Hashash","year":"2015","journal-title":"Gastroenterol Hepatol (N Y)."},{"issue":"Pt 1","key":"2022111812294194100_CIT0033","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1042\/bj2820197","article-title":"Inhibition of folate-dependent enzymes by non-steroidal anti-inflammatory drugs.","volume":"282","author":"Baggott","year":"1992","journal-title":"Biochem J."},{"issue":"1","key":"2022111812294194100_CIT0034","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1053\/j.gastro.2006.04.049","article-title":"American Gastroenterological Association Institute technical review on the use of gastrointestinal medications in pregnancy.","volume":"131","author":"Mahadevan","year":"2006","journal-title":"Gastroenterology."},{"issue":"4","key":"2022111812294194100_CIT0035","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1053\/j.gastro.2020.11.038","article-title":"Pregnancy and neonatal outcomes after fetal exposure to biologics and thiopurines among women with inflammatory bowel disease.","volume":"160","author":"Mahadevan","year":"2021","journal-title":"Gastroenterology."},{"issue":"1","key":"2022111812294194100_CIT0036","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1001\/archpedi.153.1.27","article-title":"Preventive services received by adolescents with cystic fibrosis and sickle cell disease.","volume":"153","author":"Britto","year":"1999","journal-title":"Arch Pediatr Adolesc Med."},{"key":"2022111812294194100_CIT0037","first-page":"A14480","article-title":"Family planning care experiences and perceptions of women with congenital heart disease. Abstracts from the American Heart Association\u2019s 2020 Scientific Sessions, held virtually.","volume":"142","author":"Stokes","year":"2020","journal-title":"Circulation"},{"issue":"5","key":"2022111812294194100_CIT0038","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1177\/2050640615580893","article-title":"Inflammatory bowel disease-specific pregnancy knowledge of gastroenterologists against general practitioners and obstetricians.","volume":"3","author":"Kashkooli","year":"2015","journal-title":"United European Gastroenterol J."},{"issue":"2","key":"2022111812294194100_CIT0039","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.contraception.2020.11.001","article-title":"Contraception decision-making and care among reproductive-aged women with autoimmune diseases.","volume":"103","author":"Stransky","year":"2021","journal-title":"Contraception."}],"container-title":["Crohn's &amp; Colitis 360"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/crohnscolitis360\/advance-article-pdf\/doi\/10.1093\/crocol\/otab083\/41966390\/otab083.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/crohnscolitis360\/article-pdf\/4\/1\/otab083\/47118194\/otab083.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/crohnscolitis360\/article-pdf\/4\/1\/otab083\/47118194\/otab083.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T12:31:02Z","timestamp":1668774662000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/crohnscolitis360\/article\/doi\/10.1093\/crocol\/otab083\/6487381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,29]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/crocol\/otab083","relation":{},"ISSN":["2631-827X"],"issn-type":[{"value":"2631-827X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,1,1]]},"published":{"date-parts":[[2021,12,29]]},"article-number":"otab083"}}