{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T11:04:19Z","timestamp":1782299059690,"version":"3.54.5"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,3,23]],"date-time":"2024-03-23T00:00:00Z","timestamp":1711152000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Yale School of Medicine Office of Student Research"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Colonoscopy withdrawal time (CWT) of at least 6\u20139 minutes is the minimum time needed for adequate adenoma detection in the general population. The ideal CWT in patients with inflammatory bowel disease (IBD) has not been determined. We aimed to identify the optimal CWT associated with the detection of visible dysplasia in patients with IBD.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This is a retrospective study from 1\/1\/2017 to 9\/1\/2022 of adult patients with IBD in endoscopic healing undergoing surveillance via high-definition white light colonoscopy. The primary outcome was the association of CWT with visible dysplasia detection.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 259 patients (mean age 56\u2005\u00b1\u200514.8 years; 51.3% female, 68% with ulcerative colitis; 8.9% with primary sclerosing cholangitis) underwent 330 colonoscopies. Patients with visible dysplasia were more likely to be older (P\u2005&amp;lt;\u2005.001) and have a personal history of visible dysplasia (P\u2005&amp;lt;\u2005.001) and invisible dysplasia (P\u2005=\u2005.023). The mean CWT was significantly longer in the visible dysplasia group at 26 minutes (interquartile range [IQR] 20\u201338.5) vs. 21 minutes (IQR 15\u201328) in procedures without visible dysplasia (P\u2005&amp;lt;\u2005.001). On multivariable analysis, increased age (P\u2005&amp;lt;\u2005.001), increased CWT (P\u2005=\u2005.001), and personal history of visible dysplasia (P\u2005=\u2005.013) were independently associated with the detection of visible dysplasia. A CWT of \u226515 minutes (odds ratio [OR] 2.71; 95% confidence interval [CI], 1.11\u20136.6; P\u2005=\u2005.02] and not \u22659 minutes (OR 2.57; 95% CI, 0.33\u201320.2; P\u2005=\u2005.35) is significantly associated with detection of visible dysplasia.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>For patients with IBD undergoing surveillance via high-definition white light colonoscopy, the mean CWT was independently associated with the detection of visible dysplasia.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/crocol\/otae020","type":"journal-article","created":{"date-parts":[[2024,3,23]],"date-time":"2024-03-23T13:20:05Z","timestamp":1711200005000},"source":"Crossref","is-referenced-by-count":3,"title":["Longer Colonoscopy Withdrawal Time Is Associated With the Detection of Visible Dysplasia in Patients With Inflammatory Bowel Disease"],"prefix":"10.1093","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6758-693X","authenticated-orcid":false,"given":"Chandler","family":"McMillan","sequence":"first","affiliation":[{"name":"Yale School of Medicine , New Haven, CT , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darrick K","family":"Li","sequence":"additional","affiliation":[{"name":"Section of Digestive Diseases, Yale School of Medicine , New Haven, CT , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamal","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Epidemiology and Scientific Computing, King Faisal Specialist Hospital , Riyadh , Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danah A","family":"Alsadoun","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Epidemiology and Scientific Computing, King Faisal Specialist Hospital , Riyadh , Saudi 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3905-2903","authenticated-orcid":false,"given":"Badr","family":"Al-Bawardy","sequence":"additional","affiliation":[{"name":"Section of Digestive Diseases, Yale School of Medicine , New Haven, CT , USA"},{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, King Faisal Specialist Hospital , Riyadh , Saudi Arabia"},{"name":"College of Medicine, Alfaisal University , Riyadh , Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,3,23]]},"reference":[{"issue":"Suppl 2","key":"2024040612013362800_CIT0001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1365-2036.18.s2.2.x","article-title":"Review article: the incidence and prevalence of colorectal cancer in inflammatory bowel disease","volume":"18","author":"Munkholm","year":"2003","journal-title":"Aliment Pharmacol 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