{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T13:03:00Z","timestamp":1793797380216,"version":"4.6.1"},"reference-count":194,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T00:00:00Z","timestamp":1619654400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,6,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Atrial fibrillation (AF) has heterogeneous patterns of presentation concerning symptoms, duration of episodes, AF burden, and the tendency to progress towards the terminal step of permanent AF. AF is associated with a risk of stroke\/thromboembolism traditionally considered dependent on patient-level risk factors rather than AF type, AF burden, or other characterizations. However, the time spent in AF appears related to an incremental risk of stroke, as suggested by the higher risk of stroke in patients with clinical AF vs. subclinical episodes and in patients with non-paroxysmal AF vs. paroxysmal AF. In patients with device-detected atrial tachyarrhythmias, AF burden is a dynamic process with potential transitions from a lower to a higher maximum daily arrhythmia burden, thus justifying monitoring its temporal evolution. In clinical terms, the appearance of the first episode of AF, the characterization of the arrhythmia in a specific AF type, the progression of AF, and the response to rhythm control therapies, as well as the clinical outcomes, are all conditioned by underlying heart disease, risk factors, and comorbidities. Improved understanding is needed on how to monitor and modulate the effect of factors that condition AF susceptibility and modulate AF-associated outcomes. The increasing use of wearables and apps in practice and clinical research may be useful to predict and quantify AF burden and assess AF susceptibility at the individual patient level. This may help us reveal why AF stops and starts again, or why AF episodes, or burden, cluster. Additionally, whether the distribution of burden is associated with variations in the propensity to thrombosis or other clinical adverse events. Combining the improved methods for data analysis, clinical and translational science could be the basis for the early identification of the subset of patients at risk of progressing to a longer duration\/higher burden of AF and the associated adverse outcomes.<\/jats:p>","DOI":"10.1093\/cvr\/cvab147","type":"journal-article","created":{"date-parts":[[2021,4,23]],"date-time":"2021-04-23T08:58:37Z","timestamp":1619168317000},"page":"1-21","source":"Crossref","is-referenced-by-count":97,"title":["Optimizing indices of atrial fibrillation susceptibility and burden to evaluate atrial fibrillation severity, risk and outcomes"],"prefix":"10.1093","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9820-4815","authenticated-orcid":false,"given":"Giuseppe","family":"Boriani","sequence":"first","affiliation":[{"name":"Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Via del Pozzo, 71, 41124 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5196-6249","authenticated-orcid":false,"given":"Marco","family":"Vitolo","sequence":"additional","affiliation":[{"name":"Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Via del Pozzo, 71, 41124 Modena, Italy"},{"name":"Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, UK"},{"name":"Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Diemberger","sequence":"additional","affiliation":[{"name":"Department of Experimental, Diagnostic and Specialty Medicine, Institute of Cardiology, University of Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1452-2478","authenticated-orcid":false,"given":"Marco","family":"Proietti","sequence":"additional","affiliation":[{"name":"Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, UK"},{"name":"Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy"},{"name":"Geriatric Unit, IRCCS Istituti Clinici Scientifici Maugeri, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Chiara","family":"Valenti","sequence":"additional","affiliation":[{"name":"Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Via del Pozzo, 71, 41124 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo Livio","family":"Malavasi","sequence":"additional","affiliation":[{"name":"Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Via del Pozzo, 71, 41124 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory Y H","family":"Lip","sequence":"additional","affiliation":[{"name":"Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, UK"},{"name":"Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,4,29]]},"reference":[{"key":"2021122415314915800_cvab147-B1","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.chest.2018.07.040","article-title":"Antithrombotic therapy for atrial fibrillation: CHEST guideline and expert panel report","volume":"154","author":"Lip","year":"2018","journal-title":"Chest"},{"key":"2021122415314915800_cvab147-B2","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1093\/europace\/eux301","article-title":"Contemporary stroke prevention strategies in 11\u2009096 European patients with atrial fibrillation: a report from the EURObservational Research Programme on Atrial Fibrillation (EORP-AF) Long-Term General Registry","volume":"20","author":"Boriani","year":"2018","journal-title":"Europace"},{"key":"2021122415314915800_cvab147-B3","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1093\/europace\/euaa274","article-title":"Relation of outcomes to ABC (Atrial Fibrillation Better Care) pathway adherent care in European patients with atrial fibrillation: an analysis from the ESC-EHRA EORP Atrial Fibrillation General Long-Term (AFGen LT) Registry","volume":"23","author":"Proietti","year":"2021","journal-title":"Europace"},{"key":"2021122415314915800_cvab147-B4","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1007\/s11739-020-02405-0","article-title":"The Euro Heart Survey and EURObservational Research Programme (EORP) in atrial fibrillation registries: contribution to epidemiology, clinical management and therapy of atrial fibrillation patients over the last 20 years","volume":"15","author":"Vitolo","year":"2020","journal-title":"Intern Emerg Med"},{"key":"2021122415314915800_cvab147-B5","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/eurheartj\/ehaa612","article-title":"2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"42","author":"Hindricks","year":"2021","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B6","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1378\/chest.09-1584","article-title":"Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the euro heart survey on atrial fibrillation","volume":"137","author":"Lip","year":"2010","journal-title":"Chest"},{"key":"2021122415314915800_cvab147-B7","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.cjca.2019.02.009","article-title":"Stroke prevention, evaluation of bleeding risk, and anticoagulant treatment management in atrial fibrillation contemporary international guidelines","volume":"35","author":"Proietti","year":"2019","journal-title":"Can J Cardiol"},{"key":"2021122415314915800_cvab147-B8","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1161\/STROKEAHA.118.024305","article-title":"Refining stroke and bleeding prediction in atrial fibrillation by adding consecutive biomarkers to clinical risk scores","volume":"50","author":"Rivera-Caravaca","year":"2019","journal-title":"Stroke"},{"key":"2021122415314915800_cvab147-B9","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1111\/ijcp.12326","article-title":"AF burden is important\u2014fact or fiction?","volume":"68","author":"Boriani","year":"2014","journal-title":"Int J Clin Pract"},{"key":"2021122415314915800_cvab147-B10","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.vph.2016.03.006","article-title":"Atrial fibrillation burden and atrial fibrillation type: clinical significance and impact on the risk of stroke and decision making for long-term anticoagulation","volume":"83","author":"Boriani","year":"2016","journal-title":"Vascul Pharmacol"},{"key":"2021122415314915800_cvab147-B11","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1002\/ejhf.1745","article-title":"Atrial fibrillation and remote monitoring through cardiac implantable electronic devices in heart failure patients","volume":"22","author":"Boriani","year":"2020","journal-title":"Eur J Heart Fail"},{"key":"2021122415314915800_cvab147-B12","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.33963\/KP.15110","article-title":"Atrial fibrillation in patients with cardiac implantable electronic devices: new perspectives with important clinical implications","volume":"77","author":"Boriani","year":"2019","journal-title":"Kardiol Pol"},{"key":"2021122415314915800_cvab147-B13","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1161\/CIRCULATIONAHA.116.026693","article-title":"Screening for atrial fibrillation: a report of the AF-SCREEN International Collaboration","volume":"135","author":"Freedman","year":"2017","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B14","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1055\/s-0040-1716408","article-title":"The 4S-AF scheme (Stroke Risk; Symptoms; Severity of Burden; Substrate): a novel approach to in-depth characterization (rather than classification) of atrial fibrillation","volume":"121","author":"Potpara","year":"2021","journal-title":"Thromb Haemost"},{"key":"2021122415314915800_cvab147-B15","doi-asserted-by":"crossref","first-page":"e623","DOI":"10.1161\/CIR.0000000000000568","article-title":"Atrial fibrillation burden: moving beyond atrial fibrillation as a binary entity: a scientific statement from the American Heart Association","volume":"137","author":"Chen","year":"2018","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B16","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1093\/europace\/euv390","article-title":"\u2018Real-world\u2019 management and outcomes of patients with paroxysmal vs. non-paroxysmal atrial fibrillation in Europe: the EURObservational Research Programme-Atrial Fibrillation (EORP-AF) General Pilot Registry","volume":"18","author":"Boriani","year":"2016","journal-title":"Europace"},{"key":"2021122415314915800_cvab147-B17","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1093\/eurheartj\/ehw007","article-title":"The impact of atrial fibrillation type on the risk of thromboembolism, mortality, and bleeding: a systematic review and meta-analysis","volume":"37","author":"Ganesan","year":"2016","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B18","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/eurheartj\/ehu307","article-title":"Risk of ischaemic stroke according to pattern of atrial fibrillation: analysis of 6563 aspirin-treated patients in ACTIVE-A and AVERROES","volume":"36","author":"Vanassche","year":"2015","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B19","doi-asserted-by":"crossref","first-page":"2771","DOI":"10.1016\/j.jacc.2019.09.050","article-title":"Natural history of subclinical atrial fibrillation detected by implanted loop recorders","volume":"74","author":"Diederichsen","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B20","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1093\/eurheartj\/eht491","article-title":"Device-detected atrial fibrillation and risk for stroke: an analysis of &gt;10,000 patients from the SOS AF project (Stroke preventiOn Strategies based on Atrial Fibrillation information from implanted devices)","volume":"35","author":"Boriani","year":"2014","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B21","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/nrcardio.2017.94","article-title":"Management of atrial high-rate episodes detected by cardiac implanted electronic devices","volume":"14","author":"Freedman","year":"2017","journal-title":"Nat Rev Cardiol"},{"key":"2021122415314915800_cvab147-B22","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1093\/eurheartj\/ehx731","article-title":"Subclinical device-detected atrial fibrillation and stroke risk: a systematic review and meta-analysis","volume":"39","author":"Mahajan","year":"2018","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B23","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1001\/jamacardio.2018.1205","article-title":"When low-risk atrial fibrillation is not so low risk: beast of burden","volume":"3","author":"Steinberg","year":"2018","journal-title":"JAMA Cardiol"},{"key":"2021122415314915800_cvab147-B24","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ijcard.2019.07.039","article-title":"Oral anticoagulation for subclinical atrial tachyarrhythmias detected by implantable cardiac devices: an international survey of the AF-SCREEN Group","volume":"296","author":"Boriani","year":"2019","journal-title":"Int J Cardiol"},{"key":"2021122415314915800_cvab147-B25","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.1161\/CIRCULATIONAHA.118.038988","article-title":"Practice variation in anticoagulation prescription and outcomes after device-detected atrial fibrillation","volume":"139","author":"Perino","year":"2019","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B26","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.ahj.2017.04.008","article-title":"Rationale and design of the Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation (ARTESiA) trial","volume":"189","author":"Lopes","year":"2017","journal-title":"Am Heart J"},{"key":"2021122415314915800_cvab147-B27","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.ahj.2017.04.015","article-title":"Probing oral anticoagulation in patients with atrial high rate episodes: rationale and design of the Non-vitamin K antagonist Oral anticoagulants in patients with Atrial High rate episodes (NOAH-AFNET 6) trial","volume":"190","author":"Kirchhof","year":"2017","journal-title":"Am Heart J"},{"key":"2021122415314915800_cvab147-B28","doi-asserted-by":"crossref","first-page":"O42","DOI":"10.1093\/eurheartj\/suaa179","article-title":"What do we do about atrial high rate episodes?","volume":"22","author":"Boriani","year":"2020","journal-title":"Eur Heart J Suppl"},{"key":"2021122415314915800_cvab147-B29","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.hrthm.2017.11.007","article-title":"Detection of new atrial fibrillation in patients with cardiac implanted electronic devices and factors associated with transition to higher device-detected atrial fibrillation burden","volume":"15","author":"Boriani","year":"2018","journal-title":"Heart Rhythm"},{"key":"2021122415314915800_cvab147-B30","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1093\/europace\/euaa123","article-title":"Temporal patterns and short-term progression of paroxysmal atrial fibrillation: data from RACE V","volume":"22","author":"De With","year":"2020","journal-title":"Europace"},{"key":"2021122415314915800_cvab147-B31","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.jacc.2015.05.018","article-title":"Excessive atrial ectopy and short atrial runs increase the risk of stroke beyond incident atrial fibrillation","volume":"66","author":"Larsen","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B32","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1161\/CIRCULATIONAHA.112.098079","article-title":"A comprehensive evaluation of rhythm monitoring strategies for the detection of atrial fibrillation recurrence: insights from 647 continuously monitored patients and implications for monitoring after therapeutic interventions","volume":"126","author":"Charitos","year":"2012","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B33","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.hrthm.2020.10.017","article-title":"Relationship between device-detected burden and duration of atrial fibrillation and risk of ischemic stroke","volume":"18","author":"Al-Gibbawi","year":"2021","journal-title":"Heart Rhythm"},{"key":"2021122415314915800_cvab147-B34","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1161\/STROKEAHA.110.609297","article-title":"Improving stroke risk stratification using the CHADS2 and CHA2DS2-VASc risk scores in patients with paroxysmal atrial fibrillation by continuous arrhythmia burden monitoring","volume":"42","author":"Boriani","year":"2011","journal-title":"Stroke"},{"key":"2021122415314915800_cvab147-B35","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1161\/CIRCULATIONAHA.119.041303","article-title":"Stroke risk as a function of atrial fibrillation duration and CHA2DS2-VASc score","volume":"140","author":"Kaplan","year":"2019","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B36","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.ahj.2019.09.009","article-title":"Incidence and predictors of atrial fibrillation episodes as detected by implantable loop recorder in patients at risk: from the LOOP study","volume":"219","author":"Diederichsen","year":"2020","journal-title":"Am Heart J"},{"key":"2021122415314915800_cvab147-B37","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.hrthm.2017.04.026","article-title":"Predicting determinants of atrial fibrillation or flutter for therapy elucidation in patients at risk for thromboembolic events (PREDATE AF) study","volume":"14","author":"Nasir","year":"2017","journal-title":"Heart Rhythm"},{"key":"2021122415314915800_cvab147-B38","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1001\/jamacardio.2017.3180","article-title":"Incidence of previously undiagnosed atrial fibrillation using insertable cardiac monitors in a high-risk population: the REVEAL AF study","volume":"2","author":"Reiffel","year":"2017","journal-title":"JAMA Cardiol"},{"key":"2021122415314915800_cvab147-B39","doi-asserted-by":"crossref","first-page":"e007953","DOI":"10.1161\/CIRCEP.120.007953","article-title":"Digital health and the care of the patient with arrhythmia: what every electrophysiologist needs to know","volume":"13","author":"Tarakji","year":"2020","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2021122415314915800_cvab147-B40","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.ejim.2020.09.005","article-title":"Consumer-led screening for atrial fibrillation using consumer-facing wearables, devices and apps: a survey of health care professionals by AF-SCREEN international collaboration","volume":"82","author":"Boriani","year":"2020","journal-title":"Eur J Intern Med"},{"key":"2021122415314915800_cvab147-B41","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1161\/CIRCEP.114.003057","article-title":"Atrial fibrillation burden and short-term risk of stroke: case-crossover analysis of continuously recorded heart rhythm from cardiac electronic implanted devices","volume":"8","author":"Turakhia","year":"2015","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2021122415314915800_cvab147-B42","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1161\/STROKEAHA.115.012004","article-title":"Atrial fibrillation and mechanisms of stroke: time for a new model","volume":"47","author":"Kamel","year":"2016","journal-title":"Stroke"},{"key":"2021122415314915800_cvab147-B43","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1161\/CIRCULATIONAHA.113.007825","article-title":"Temporal relationship between subclinical atrial fibrillation and embolic events","volume":"129","author":"Brambatti","year":"2014","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B44","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1093\/europace\/euw161","article-title":"EHRA\/HRS\/APHRS\/SOLAECE expert consensus on atrial cardiomyopathies: definition, characterization, and clinical implication","volume":"18","author":"Goette","year":"2016","journal-title":"Europace"},{"key":"2021122415314915800_cvab147-B45","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.jacc.2019.11.013","article-title":"Atrial failure as a clinical entity: JACC review topic of the week","volume":"75","author":"Bisbal","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B46","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1161\/01.CIR.89.2.724","article-title":"Echocardiographic predictors of nonrheumatic atrial fibrillation. The Framingham Heart Study","volume":"89","author":"Vaziri","year":"1994","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B47","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1161\/01.CIR.96.7.2455","article-title":"Incidence of and risk factors for atrial fibrillation in older adults","volume":"96","author":"Psaty","year":"1997","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B48","doi-asserted-by":"crossref","first-page":"467","DOI":"10.4065\/76.5.467","article-title":"Left atrial volume: important risk marker of incident atrial fibrillation in 1655 older men and women","volume":"76","author":"Tsang","year":"2001","journal-title":"Mayo Clinic Proc"},{"key":"2021122415314915800_cvab147-B49","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.jacc.2005.08.077","article-title":"Prediction of cardiovascular outcomes with left atrial size: is volume superior to area or diameter?","volume":"47","author":"Tsang","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B50","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1016\/j.amjcard.2008.01.051","article-title":"Left atrial reservoir function as a potent marker for first atrial fibrillation or flutter in persons &gt; or = 65 years of age","volume":"101","author":"Abhayaratna","year":"2008","journal-title":"Am J Cardiol"},{"key":"2021122415314915800_cvab147-B51","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.141656","article-title":"Characterization of cardiac mechanics and incident atrial fibrillation in participants of the Cardiovascular Health Study","volume":"5","author":"Patel","year":"2020","journal-title":"JCI Insight"},{"key":"2021122415314915800_cvab147-B52","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/S0008-6363(02)00258-4","article-title":"Electrical, contractile and structural remodeling during atrial fibrillation","volume":"54","author":"Allessie","year":"2002","journal-title":"Cardiovasc Res"},{"key":"2021122415314915800_cvab147-B53","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1093\/europace\/euy028","article-title":"Atrial fibrillation progression and outcome in patients with young-onset atrial fibrillation","volume":"20","author":"De With","year":"2018","journal-title":"Europace"},{"key":"2021122415314915800_cvab147-B54","article-title":"Atrial fibrillation pattern and factors affecting the progression to permanent atrial fibrillation","author":"Malavasi","year":"2020","journal-title":"Intern Emerg Med"},{"key":"2021122415314915800_cvab147-B55","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1161\/01.CIR.92.4.835","article-title":"Left atrial size and the risk of stroke and death. The Framingham Heart Study","volume":"92","author":"Benjamin","year":"1995","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B56","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1161\/STROKEAHA.115.008711","article-title":"Left atrial enlargement and stroke recurrence: the Northern Manhattan Stroke Study","volume":"46","author":"Yaghi","year":"2015","journal-title":"Stroke"},{"key":"2021122415314915800_cvab147-B57","doi-asserted-by":"crossref","first-page":"797","DOI":"10.2459\/JCM.0000000000000886","article-title":"Left atrium: a forgotten biomarker and a potential target in cardiovascular medicine","volume":"20","author":"Inciardi","year":"2019","journal-title":"J Cardiovasc Med (Hagerstown)"},{"key":"2021122415314915800_cvab147-B58","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1161\/STROKEAHA.117.020059","article-title":"Atrial cardiopathy and the risk of ischemic stroke in the CHS (Cardiovascular Health Study)","volume":"49","author":"Kamel","year":"2018","journal-title":"Stroke"},{"key":"2021122415314915800_cvab147-B59","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.jns.2019.05.012","article-title":"Atrial fibrillation, not atrial cardiopathy, is associated with stroke: a single center retrospective study","volume":"402","author":"Affan","year":"2019","journal-title":"J Neurolog Sci"},{"key":"2021122415314915800_cvab147-B60","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1161\/01.CIR.0000055314.10801.4F","article-title":"Electrical and contractile remodeling during the first days of atrial fibrillation go hand in hand","volume":"107","author":"Schotten","year":"2003","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B61","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1067\/mhj.2002.123113","article-title":"Transient atrial mechanical dysfunction (stunning) after cardioversion of atrial fibrillation and flutter","volume":"144","author":"Khan","year":"2002","journal-title":"Am Heart J"},{"key":"2021122415314915800_cvab147-B62","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1016\/0735-1097(94)90652-1","article-title":"Impaired left atrial mechanical function after cardioversion: relation to the duration of atrial fibrillation","volume":"23","author":"Manning","year":"1994","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B63","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.jacep.2016.02.010","article-title":"The substrate in \"early persistent\" atrial fibrillation: arrhythmia induced, risk factor induced, or from a specific fibrotic atrial cardiomyopathy?","volume":"2","author":"Kottkamp","year":"2016","journal-title":"JACC Clin Electrophysiol"},{"key":"2021122415314915800_cvab147-B64","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.jacep.2017.03.002","article-title":"Molecular and cellular mechanisms of atrial fibrosis in atrial fibrillation","volume":"3","author":"Nattel","year":"2017","journal-title":"JACC Clin Electrophysiol"},{"key":"2021122415314915800_cvab147-B65","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1161\/CIRCRESAHA.120.316340","article-title":"Epidemiology of atrial fibrillation in the 21st century: novel methods and new insights","volume":"127","author":"Kornej","year":"2020","journal-title":"Circ Res"},{"key":"2021122415314915800_cvab147-B66","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1161\/CIRCRESAHA.114.303211","article-title":"The clinical profile and pathophysiology of atrial fibrillation: relationships among clinical features, epidemiology, and mechanisms","volume":"114","author":"Andrade","year":"2014","journal-title":"Circ Res"},{"key":"2021122415314915800_cvab147-B67","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1161\/CIRCRESAHA.117.309732","article-title":"Atrial fibrillation: epidemiology, pathophysiology, and clinical outcomes","volume":"120","author":"Staerk","year":"2017","journal-title":"Circ Res"},{"key":"2021122415314915800_cvab147-B68","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1001\/jama.1994.03510350050036","article-title":"Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study","volume":"271","author":"Benjamin","year":"1994","journal-title":"JAMA"},{"key":"2021122415314915800_cvab147-B69","article-title":"The management of atrial fibrillation in heart failure: an expert panel consensus","author":"Farmakis","year":"2020","journal-title":"Heart Fail Rev"},{"key":"2021122415314915800_cvab147-B70","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1161\/CIRCULATIONAHA.115.018614","article-title":"Atrial fibrillation begets heart failure and vice versa: temporal associations and differences in preserved versus reduced ejection fraction","volume":"133","author":"Santhanakrishnan","year":"2016","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B71","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1002\/ejhf.510","article-title":"Physicians' adherence to guideline-recommended medications in heart failure with reduced ejection fraction: data from the QUALIFY global survey","volume":"18","author":"Komajda","year":"2016","journal-title":"Eur J Heart Fail"},{"key":"2021122415314915800_cvab147-B72","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/nrcardio.2015.191","article-title":"Comorbidity of atrial fibrillation and heart failure","volume":"13","author":"Ling","year":"2016","journal-title":"Nat Rev Cardiol"},{"key":"2021122415314915800_cvab147-B73","doi-asserted-by":"crossref","first-page":"e012554","DOI":"10.1161\/JAHA.119.012554","article-title":"Incidence and predictors of atrial fibrillation progression","volume":"8","author":"Blum","year":"2019","journal-title":"J Am Heart Assoc"},{"key":"2021122415314915800_cvab147-B74","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.jchf.2019.03.005","article-title":"Heart failure and atrial fibrillation, like fire and fury","volume":"7","author":"Carlisle","year":"2019","journal-title":"JACC Heart Fail"},{"key":"2021122415314915800_cvab147-B75","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.1016\/j.jacc.2017.09.027","article-title":"Type of atrial fibrillation and outcomes in patients with heart failure and reduced ejection fraction","volume":"70","author":"Mogensen","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B76","doi-asserted-by":"crossref","first-page":"2603","DOI":"10.1016\/j.jacc.2018.03.519","article-title":"Progression of device-detected subclinical atrial fibrillation and the risk of heart failure","volume":"71","author":"Wong","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B77","doi-asserted-by":"crossref","first-page":"2920","DOI":"10.1161\/01.CIR.0000072767.89944.6E","article-title":"Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: the Framingham Heart Study","volume":"107","author":"Wang","year":"2003","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B78","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1093\/eurjhf\/hfp085","article-title":"A meta-analysis of the prognostic significance of atrial fibrillation in chronic heart failure","volume":"11","author":"Mamas","year":"2009","journal-title":"Eur J Heart Fail"},{"key":"2021122415314915800_cvab147-B79","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ijcard.2018.04.093","article-title":"Heart failure subtypes and thromboembolic risk in patients with atrial fibrillation: the PREFER in AF-HF substudy","volume":"265","author":"Siller-Matula","year":"2018","journal-title":"Int J Cardiol"},{"key":"2021122415314915800_cvab147-B80","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1016\/j.amjcard.2019.02.027","article-title":"Impact of heart failure type on thromboembolic and bleeding risk in patients with atrial fibrillation on oral anticoagulation","volume":"123","author":"Mentias","year":"2019","journal-title":"Am J Cardiol"},{"key":"2021122415314915800_cvab147-B81","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1161\/01.CIR.100.1.87","article-title":"Promotion of atrial fibrillation by heart failure in dogs: atrial remodeling of a different sort","volume":"100","author":"Li","year":"1999","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B82","doi-asserted-by":"crossref","first-page":"C45","DOI":"10.1093\/eurheartj\/18.suppl_C.45","article-title":"Management of atrial fibrillation in the setting of heart failure","volume":"18(Suppl. C","author":"Crijns","year":"1997","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B83","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1056\/NEJMoa2019422","article-title":"Early rhythm-control therapy in patients with atrial fibrillation","volume":"383","author":"Kirchhof","year":"2020","journal-title":"N Engl J Med"},{"key":"2021122415314915800_cvab147-B84","doi-asserted-by":"crossref","first-page":"3021","DOI":"10.1093\/eurheartj\/ehy339","article-title":"2018 ESC\/ESH Guidelines for the management of arterial hypertension","volume":"39","author":"Williams","year":"2018","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B85","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1056\/NEJM198204293061703","article-title":"Epidemiologic features of chronic atrial fibrillation: the Framingham study","volume":"306","author":"Kannel","year":"1982","journal-title":"N Engl J Med"},{"key":"2021122415314915800_cvab147-B86","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/S0002-9343(99)80348-9","article-title":"The natural history of atrial fibrillation: incidence, risk factors, and prognosis in the Manitoba Follow-Up Study","volume":"98","author":"Krahn","year":"1995","journal-title":"Am J Med"},{"key":"2021122415314915800_cvab147-B87","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1161\/CIRCULATIONAHA.110.009035","article-title":"Absolute and attributable risks of atrial fibrillation in relation to optimal and borderline risk factors: the Atherosclerosis Risk in Communities (ARIC) study","volume":"123","author":"Huxley","year":"2011","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B88","doi-asserted-by":"crossref","first-page":"2988","DOI":"10.3390\/jcm9092988","article-title":"What is the ideal blood pressure threshold for the prevention of atrial fibrillation in elderly general population?","volume":"9","author":"Park","year":"2020","journal-title":"J Clin Med"},{"key":"2021122415314915800_cvab147-B89","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1161\/01.HYP.0000052830.02773.E4","article-title":"Atrial fibrillation in hypertension: predictors and outcome","volume":"41","author":"Verdecchia","year":"2003","journal-title":"Hypertension"},{"key":"2021122415314915800_cvab147-B90","doi-asserted-by":"crossref","first-page":"6366","DOI":"10.1038\/s41598-018-24875-1","article-title":"Association between atrial fibrillation, atrial enlargement, and left ventricular geometric remodeling","volume":"8","author":"Seko","year":"2018","journal-title":"Sci Rep"},{"key":"2021122415314915800_cvab147-B91","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1016\/j.jacc.2014.01.066","article-title":"Association of electrocardiographic and imaging surrogates of left ventricular hypertrophy with incident atrial fibrillation: MESA (Multi-Ethnic Study of Atherosclerosis)","volume":"63","author":"Chrispin","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B92","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.jacc.2004.10.068","article-title":"Angiotensin II receptor blockade reduces new-onset atrial fibrillation and subsequent stroke compared to atenolol: the Losartan Intervention For End Point Reduction in Hypertension (LIFE) study","volume":"45","author":"Wachtell","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B93","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1001\/jama.296.10.1242","article-title":"Regression of electrocardiographic left ventricular hypertrophy and decreased incidence of new-onset atrial fibrillation in patients with hypertension","volume":"296","author":"Okin","year":"2006","journal-title":"JAMA"},{"key":"2021122415314915800_cvab147-B94","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.ahj.2012.02.015","article-title":"Progression of atrial fibrillation in the REgistry on Cardiac rhythm disORDers assessing the control of Atrial Fibrillation cohort: clinical correlates and the effect of rhythm-control therapy","volume":"163","author":"De Vos","year":"2012","journal-title":"Am Heart J"},{"key":"2021122415314915800_cvab147-B95","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.amjcard.2018.04.053","article-title":"Effect of systemic hypertension with versus without left ventricular hypertrophy on the progression of atrial fibrillation (from the Euro Heart Survey)","volume":"122","author":"Erk\u00fcner","year":"2018","journal-title":"Am J Cardiol"},{"key":"2021122415314915800_cvab147-B96","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1093\/eurheartj\/ehs341","article-title":"Gender-specific differences in left ventricular remodelling in obesity: insights from cardiovascular magnetic resonance imaging","volume":"34","author":"Rider","year":"2013","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B97","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1093\/eurheartj\/ehl504","article-title":"Effect of hypertension on anticoagulated patients with atrial fibrillation","volume":"28","author":"Lip","year":"2007","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B98","doi-asserted-by":"crossref","first-page":"e002015","DOI":"10.1161\/JAHA.115.002015","article-title":"Blood pressure control and risk of stroke or systemic embolism in patients with atrial fibrillation: results from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial","volume":"4","author":"Rao","year":"2015","journal-title":"J Am Heart Assoc"},{"key":"2021122415314915800_cvab147-B99","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ahj.2016.05.001","article-title":"Blood pressure control and stroke or bleeding risk in anticoagulated patients with atrial fibrillation: results from the ROCKET AF Trial","volume":"178","author":"Vemulapalli","year":"2016","journal-title":"Am Heart J"},{"key":"2021122415314915800_cvab147-B100","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1161\/HYPERTENSIONAHA.120.16025","article-title":"Blood pressure and brain lesions in patients with atrial fibrillation","volume":"77","author":"Aeschbacher","year":"2021","journal-title":"Hypertension"},{"key":"2021122415314915800_cvab147-B101","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1093\/ajh\/hpaa157","article-title":"Why is atrial fibrillation so frequent in hypertensive patients?","volume":"33","author":"Vitolo","year":"2020","journal-title":"Am J Hypertens"},{"key":"2021122415314915800_cvab147-B102","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1038\/s41371-019-0279-7","article-title":"Invited review: hypertension and atrial fibrillation: epidemiology, pathophysiology, and implications for management","volume":"33","author":"Gumprecht","year":"2019","journal-title":"J Hum Hypertens"},{"key":"2021122415314915800_cvab147-B103","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1152\/physrev.00031.2009","article-title":"Pathophysiological mechanisms of atrial fibrillation: a translational appraisal","volume":"91","author":"Schotten","year":"2011","journal-title":"Physiol Rev"},{"key":"2021122415314915800_cvab147-B104","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s40256-019-00374-0","article-title":"Obesity paradox in atrial fibrillation: implications for outcomes and relationship with oral anticoagulant drugs","volume":"20","author":"Proietti","year":"2020","journal-title":"Am J Cardiovasc Drugs"},{"key":"2021122415314915800_cvab147-B105","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.ahj.2007.10.004","article-title":"Atrial fibrillation and obesity\u2014results of a meta-analysis","volume":"155","author":"Wanahita","year":"2008","journal-title":"Am Heart J"},{"key":"2021122415314915800_cvab147-B106","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s10654-017-0232-4","article-title":"Body mass index, abdominal fatness, fat mass and the risk of atrial fibrillation: a systematic review and dose-response meta-analysis of prospective studies","volume":"32","author":"Aune","year":"2017","journal-title":"Eur J Epidemiol"},{"key":"2021122415314915800_cvab147-B107","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.amjcard.2010.10.018","article-title":"Relation of obesity to recurrence rate and burden of atrial fibrillation","volume":"107","author":"Guglin","year":"2011","journal-title":"Am J Cardiol"},{"key":"2021122415314915800_cvab147-B108","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.1093\/eurheartj\/ehn324","article-title":"Obesity as a risk factor for the progression of paroxysmal to permanent atrial fibrillation: a longitudinal cohort study of 21 years","volume":"29","author":"Tsang","year":"2008","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B109","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.amjmed.2009.11.026","article-title":"Influence of obesity on outcomes in atrial fibrillation: yet another obesity paradox","volume":"123","author":"Badheka","year":"2010","journal-title":"Am J Med"},{"key":"2021122415314915800_cvab147-B110","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1093\/eurheartj\/ehy861","article-title":"Relationship between body mass index and outcomes in patients with atrial fibrillation treated with edoxaban or warfarin in the ENGAGE AF-TIMI 48 trial","volume":"40","author":"Boriani","year":"2019","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B111","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.pcad.2018.07.003","article-title":"An overview and update on obesity and the obesity paradox in cardiovascular diseases","volume":"61","author":"Elagizi","year":"2018","journal-title":"Prog Cardiovasc Dis"},{"key":"2021122415314915800_cvab147-B112","doi-asserted-by":"crossref","first-page":"e004006","DOI":"10.1161\/JAHA.116.004006","article-title":"Relation of body mass index with adverse outcomes among patients with atrial fibrillation: a meta-analysis and systematic review","volume":"5","author":"Zhu","year":"2016","journal-title":"JAHA"},{"key":"2021122415314915800_cvab147-B113","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1161\/STROKEAHA.116.015984","article-title":"Is there an obesity paradox for outcomes in atrial fibrillation? A systematic review and meta-analysis of non-vitamin K antagonist oral anticoagulant trials","volume":"48","author":"Proietti","year":"2017","journal-title":"Stroke"},{"key":"2021122415314915800_cvab147-B114","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1016\/j.jacc.2017.09.002","article-title":"Obesity and atrial fibrillation prevalence, pathogenesis, and prognosis: effects of weight loss and exercise","volume":"70","author":"Lavie","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B115","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.ijcard.2015.05.129","article-title":"Pericardial fat and atrial fibrillation: epidemiology, mechanisms and interventions","volume":"195","author":"Al-Rawahi","year":"2015","journal-title":"Int J Cardiol"},{"key":"2021122415314915800_cvab147-B116","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1136\/heartjnl-2011-300503","article-title":"Type 2 diabetes, glucose homeostasis and incident atrial fibrillation: the Atherosclerosis Risk in Communities study","volume":"98","author":"Huxley","year":"2012","journal-title":"Heart"},{"key":"2021122415314915800_cvab147-B117","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.amjcard.2011.03.004","article-title":"Meta-analysis of cohort and case-control studies of type 2 diabetes mellitus and risk of atrial fibrillation","volume":"108","author":"Huxley","year":"2011","journal-title":"Am J Cardiol"},{"key":"2021122415314915800_cvab147-B118","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1161\/CIRCULATIONAHA.117.028981","article-title":"Sex differences and similarities in atrial fibrillation epidemiology, risk factors, and mortality in community cohorts: results from the BiomarCaRE Consortium (Biomarker for Cardiovascular Risk Assessment in Europe)","volume":"136","author":"Magnussen","year":"2017","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B119","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1093\/ehjcvp\/pvx037","article-title":"Management and prognosis of atrial fibrillation in diabetic patients: an EORP-AF General Pilot Registry report","volume":"4","author":"Fumagalli","year":"2018","journal-title":"Eur Heart J Cardiovasc Pharmacother"},{"key":"2021122415314915800_cvab147-B120","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/j.jacc.2017.07.755","article-title":"Care patterns and outcomes in atrial fibrillation patients with and without diabetes: ORBIT-AF registry","volume":"70","author":"Echouffo-Tcheugui","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B121","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/j.jacc.2019.07.020","article-title":"Atrial fibrillation and diabetes mellitus: JACC review topic of the week","volume":"74","author":"Wang","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B122","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.3389\/fphys.2018.01669","article-title":"Diabetes and arrhythmias: pathophysiology, mechanisms and therapeutic outcomes","volume":"9","author":"Grisanti","year":"2018","journal-title":"Front Physiol"},{"key":"2021122415314915800_cvab147-B123","doi-asserted-by":"crossref","first-page":"239","DOI":"10.5761\/atcs.oa.17-00045","article-title":"Glucose variability based on continuous glucose monitoring assessment is associated with postoperative complications after cardiovascular surgery","volume":"23","author":"Sato","year":"2017","journal-title":"Ann Thorac Cardiovasc Surg"},{"key":"2021122415314915800_cvab147-B124","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1093\/europace\/euv202","article-title":"Chronic kidney disease in patients with cardiac rhythm disturbances or implantable electrical devices: clinical significance and implications for decision making\u2014a position paper of the European Heart Rhythm Association endorsed by the Heart Rhythm Society and the Asia Pacific Heart Rhythm Society","volume":"17","author":"Boriani","year":"2015","journal-title":"Europace"},{"key":"2021122415314915800_cvab147-B125","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1016\/j.ahj.2010.03.027","article-title":"Chronic kidney disease and prevalent atrial fibrillation: the Chronic Renal Insufficiency Cohort (CRIC)","volume":"159","author":"Soliman","year":"2010","journal-title":"Am Heart J"},{"key":"2021122415314915800_cvab147-B126","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.2215\/CJN.04060318","article-title":"Incident atrial fibrillation and the risk of stroke in adults with chronic kidney disease: the Stockholm CREAtinine Measurements (SCREAM) Project","volume":"13","author":"Carrero","year":"2018","journal-title":"CJASN"},{"key":"2021122415314915800_cvab147-B127","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.ahj.2009.06.031","article-title":"Close bidirectional relationship between chronic kidney disease and atrial fibrillation: the Niigata preventive medicine study","volume":"158","author":"Watanabe","year":"2009","journal-title":"Am Heart J"},{"key":"2021122415314915800_cvab147-B128","doi-asserted-by":"crossref","first-page":"30271","DOI":"10.1038\/srep30271","article-title":"Glomerular filtration rate in patients with atrial fibrillation and 1-year outcomes","volume":"6","author":"Boriani","year":"2016","journal-title":"Sci Rep"},{"key":"2021122415314915800_cvab147-B129","doi-asserted-by":"crossref","first-page":"2794","DOI":"10.2174\/1381612824666180829112019","article-title":"Meta-analysis of clinical outcomes of electrical cardioversion and catheter ablation in patients with atrial fibrillation and chronic kidney disease","volume":"24","author":"Diemberger","year":"2018","journal-title":"CPD"},{"key":"2021122415314915800_cvab147-B130","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1093\/cvr\/cvaa258","article-title":"Pathophysiology of atrial fibrillation and chronic kidney disease","volume":"117","author":"Ding","year":"2020","journal-title":"Cardiovasc Res"},{"key":"2021122415314915800_cvab147-B131","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.amjcard.2014.05.048","article-title":"Meta-analysis of the influence of chronic kidney disease on the risk of thromboembolism among patients with nonvalvular atrial fibrillation","volume":"114","author":"Provid\u00eancia","year":"2014","journal-title":"Am J Cardiol"},{"key":"2021122415314915800_cvab147-B132","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1016\/j.jacc.2013.02.035","article-title":"Renal impairment and ischemic stroke risk assessment in patients with atrial fibrillation: the Loire Valley Atrial Fibrillation Project","volume":"61","author":"Banerjee","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B133","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1160\/TH13-01-0054","article-title":"Does chronic kidney disease improve the predictive value of the CHADS2 and CHA2DS2-VASc stroke stratification risk scores for atrial fibrillation?","volume":"109","author":"Rold\u00e1n","year":"2013","journal-title":"Thromb Haemost"},{"key":"2021122415314915800_cvab147-B134","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1016\/S0735-1097(00)00611-2","article-title":"Increased expression of extracellular signal-regulated kinase and angiotensin-converting enzyme in human atria during atrial fibrillation","volume":"35","author":"Goette","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B135","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.3389\/fphys.2018.01726","article-title":"Chronic kidney disease increases atrial fibrillation inducibility: involvement of inflammation, atrial fibrosis, and connexins","volume":"9","author":"Qiu","year":"2018","journal-title":"Front Physiol"},{"key":"2021122415314915800_cvab147-B136","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1016\/j.hrthm.2012.08.019","article-title":"Establishment of a model of atrial fibrillation associated with chronic kidney disease in rats and the role of oxidative stress","volume":"9","author":"Fukunaga","year":"2012","journal-title":"Heart Rhythm"},{"key":"2021122415314915800_cvab147-B137","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.advms.2017.06.005","article-title":"Patients with atrial fibrillation and coronary artery disease\u2014double trouble","volume":"63","author":"Michniewicz","year":"2018","journal-title":"Adv Med Sci"},{"key":"2021122415314915800_cvab147-B138","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ijcard.2018.03.058","article-title":"Atrial fibrillation and prediction of mortality by conventional clinical score systems according to the setting of care","volume":"261","author":"Diemberger","year":"2018","journal-title":"Int J Cardiol"},{"key":"2021122415314915800_cvab147-B139","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1001\/archinte.167.4.382","article-title":"Subclinical atherosclerosis and risk of atrial fibrillation: the Rotterdam study","volume":"167","author":"Heeringa","year":"2007","journal-title":"Arch Intern Med"},{"key":"2021122415314915800_cvab147-B140","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1093\/ehjci\/jex201","article-title":"Coronary artery calcium score and the long-term risk of atrial fibrillation in patients undergoing non-contrast cardiac computed tomography for suspected coronary artery disease: a Danish registry-based cohort study","volume":"19","author":"Vinter","year":"2018","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2021122415314915800_cvab147-B141","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1016\/j.amjcard.2020.03.015","article-title":"Burden of arrhythmias in acute myocardial infarction complicated by cardiogenic shock","volume":"125","author":"Vallabhajosyula","year":"2020","journal-title":"Am J Cardiol"},{"key":"2021122415314915800_cvab147-B142","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1161\/01.CIR.97.10.965","article-title":"Significance of paroxysmal atrial fibrillation complicating acute myocardial infarction in the thrombolytic era. SPRINT and Thrombolytic Survey Groups","volume":"97","author":"Eldar","year":"1998","journal-title":"Circulation"},{"key":"2021122415314915800_cvab147-B143","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/S0735-1097(97)00194-0","article-title":"Atrial fibrillation in the setting of acute myocardial infarction: the GUSTO-I experience. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries","volume":"30","author":"Crenshaw","year":"1997","journal-title":"J Am Coll Cardiol"},{"key":"2021122415314915800_cvab147-B144","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.amjcard.2019.12.009","article-title":"Changing trends in the landscape of patients hospitalized with acute myocardial infarction (2001 to 2011) (from the Worcester Heart Attack Study)","volume":"125","author":"Mercado-Lubo","year":"2020","journal-title":"Am J Cardiol"},{"key":"2021122415314915800_cvab147-B145","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1378\/chest.06-2733","article-title":"Transient atrial fibrillation complicating acute inferior myocardial infarction: implications for future risk of ischemic stroke","volume":"132","author":"Siu","year":"2007","journal-title":"Chest"},{"key":"2021122415314915800_cvab147-B146","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1160\/TH16-11-0876","article-title":"Stroke prevention in atrial fibrillation: past, present and future. Comparing the guidelines and practical decision-making","volume":"117","author":"Lip","year":"2017","journal-title":"Thromb Haemost"},{"key":"2021122415314915800_cvab147-B147","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1055\/s-0038-1675401","article-title":"Should the presence or extent of coronary artery disease be quantified in the CHA2DS2-VASc score in atrial fibrillation? A report from the Western Denmark Heart Registry","volume":"118","author":"Steensig","year":"2018","journal-title":"Thromb Haemost"},{"key":"2021122415314915800_cvab147-B148","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.amjcard.2018.09.011","article-title":"Comparison of frequency of ischemic stroke in patients with versus without coronary heart disease and without atrial fibrillation","volume":"123","author":"Olesen","year":"2019","journal-title":"Am J Cardiol"},{"key":"2021122415314915800_cvab147-B149","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/j.amjmed.2019.06.008","article-title":"Outcomes in newly diagnosed atrial fibrillation and history of acute coronary syndromes: insights from GARFIELD-AF","volume":"132","author":"Verheugt","year":"2019","journal-title":"Am J Med"},{"key":"2021122415314915800_cvab147-B150","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1136\/hrt.4.1-2.17","article-title":"INFARCTION OF THE CARDIAC AURICLES (ATRIA): CLINICAL, PATHOLOGICAL, AND EXPERIMENTAL STUDIES","volume":"4","author":"Cushing","year":"1942","journal-title":"Br Heart J"},{"key":"2021122415314915800_cvab147-B151","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.cardiores.2007.01.018","article-title":"The pharmacological response of ischemia-related atrial fibrillation in dogs: evidence for substrate-specific efficacy","volume":"74","author":"Rivard","year":"2007","journal-title":"Cardiovasc Res"},{"key":"2021122415314915800_cvab147-B152","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1161\/CIRCRESAHA.116.303849","article-title":"Epidemiology of peripheral artery disease","volume":"116","author":"Criqui","year":"2015","journal-title":"Circ Res"},{"key":"2021122415314915800_cvab147-B153","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1093\/eurheartj\/ehx095","article-title":"2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteriesEndorsed by: the European Stroke Organization (ESO)The Task Force for the Diagnosis and Treatment of Peripheral Arterial Diseases of the European Society of Cardiology (ESC) and of the European Society for Vascular Surgery (ESVS)","volume":"39","author":"Aboyans","year":"2018","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B154","doi-asserted-by":"crossref","first-page":"e009126","DOI":"10.1161\/JAHA.118.009126","article-title":"Association between peripheral artery disease and incident risk of atrial fibrillation: strong evidence coming from population-based cohort studies","volume":"7","author":"Proietti","year":"2018","journal-title":"J Am Heart Assoc"},{"key":"2021122415314915800_cvab147-B155","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1093\/europace\/euw169","article-title":"Adverse outcomes in patients with atrial fibrillation and peripheral arterial disease: a report from the EURObservational research programme pilot survey on atrial fibrillation","volume":"19","author":"Proietti","year":"2017","journal-title":"Europace"},{"key":"2021122415314915800_cvab147-B156","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.atherosclerosis.2014.12.022","article-title":"Relationship between carotid intima-media thickness and non valvular atrial fibrillation type","volume":"238","author":"Proietti","year":"2015","journal-title":"Atherosclerosis"},{"key":"2021122415314915800_cvab147-B157","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1093\/eurheartj\/eht492","article-title":"Efficacy and safety of rivaroxaban compared with warfarin in patients with peripheral artery disease and non-valvular atrial fibrillation: insights from ROCKET AF","volume":"35","author":"Jones","year":"2014","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B158","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1093\/eurheartj\/ehi825","article-title":"Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study","volume":"27","author":"Heeringa","year":"2006","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B159","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1007\/s11325-019-01945-w","article-title":"Obstructive sleep apnea and cardiovascular disease, a story of confounders!","volume":"24","author":"Collen","year":"2020","journal-title":"Sleep Breath"},{"key":"2021122415314915800_cvab147-B160","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1164\/rccm.200509-1442OC","article-title":"Association of nocturnal arrhythmias with sleep-disordered breathing: the Sleep Heart Health Study","volume":"173","author":"Mehra","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"2021122415314915800_cvab147-B161","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/eurheartj\/ehq327","article-title":"Cheyne-Stokes respiration and obstructive sleep apnoea are independent risk factors for malignant ventricular arrhythmias requiring appropriate cardioverter-defibrillator therapies in patients with congestive heart failure","volume":"32","author":"Bitter","year":"2011","journal-title":"Eur Heart J"},{"key":"2021122415314915800_cvab147-B162","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1378\/chest.106.2.466","article-title":"Cardiac arrhythmias, snoring, and sleep apnea","volume":"106","author":"Hoffstein","year":"1994","journal-title":"Chest"},{"key":"2021122415314915800_cvab147-B163","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.sleep.2012.08.021","article-title":"The association between atrial fibrillation and stroke in patients with obstructive sleep apnea: a population-based case-control study","volume":"14","author":"Mansukhani","year":"2013","journal-title":"Sleep Med"},{"key":"2021122415314915800_cvab147-B164","first-page":"E575","article-title":"Atrial fibrillation and sleep-disordered breathing","volume":"7","author":"Lavergne","year":"2015","journal-title":"J Thorac Dis"},{"key":"2021122415314915800_cvab147-B165","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1016\/j.amjcard.2015.08.046","article-title":"Meta-analysis of continuous positive airway pressure as a therapy of atrial fibrillation in obstructive sleep apnea","volume":"116","author":"Qureshi","year":"2015","journal-title":"Am J Cardiol"},{"key":"2021122415314915800_cvab147-B166","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1007\/s11325-020-02046-9","article-title":"Association between excessive daytime sleepiness and measures of supraventricular arrhythmia burden: evidence from the Atherosclerosis Risk in Communities (ARIC) study","volume":"24","author":"Full","year":"2020","journal-title":"Sleep Breath"},{"key":"2021122415314915800_cvab147-B167","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1007\/s11325-017-1469-6","article-title":"Stratification of cardiovascular risk in patients with atrial fibrillation and obstructive sleep apnea-validity of the 2MACE score","volume":"21","author":"Platek","year":"2017","journal-title":"Sleep Breath"},{"key":"2021122415314915800_cvab147-B168","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.amjcard.2014.11.027","article-title":"Effect of obstructive sleep apnea on frequency of stroke in patients with atrial fibrillation","volume":"115","author":"Yaranov","year":"2015","journal-title":"Am J Cardiol"},{"key":"2021122415314915800_cvab147-B169","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ahj.2020.01.001","article-title":"Risk of major cardiovascular and neurologic events with obstructive sleep apnea among patients with atrial fibrillation","volume":"223","author":"Dalgaard","year":"2020","journal-title":"Am Heart J"},{"key":"2021122415314915800_cvab147-B170","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1056\/NEJMoa1606599","article-title":"CPAP for prevention of cardiovascular events in obstructive sleep apnea","volume":"375","author":"McEvoy","year":"2016","journal-title":"N Engl J Med"},{"key":"2021122415314915800_cvab147-B171","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.tcm.2008.11.008","article-title":"Inflammation, oxidative stress, and the vascular endothelium in obstructive sleep apnea","volume":"18","author":"Jelic","year":"2008","journal-title":"Trends Cardiovasc Med"},{"key":"2021122415314915800_cvab147-B172","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1007\/s40675-018-0130-7","article-title":"Connexins and atrial fibrillation in obstructive sleep apnea","volume":"4","author":"Khalyfa","year":"2018","journal-title":"Curr Sleep Med Rep"},{"key":"2021122415314915800_cvab147-B173","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"J Chronic Dis"},{"key":"2021122415314915800_cvab147-B174","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/00005650-199801000-00004","article-title":"Comorbidity measures for use with administrative data","volume":"36","author":"Elixhauser","year":"1998","journal-title":"Med Care"},{"key":"2021122415314915800_cvab147-B175","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1016\/j.mayocp.2019.06.012","article-title":"Long-term relationship between atrial fibrillation, multimorbidity and oral anticoagulant drug use","volume":"94","author":"Proietti","year":"2019","journal-title":"Mayo Clin Proc"},{"key":"2021122415314915800_cvab147-B176","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1093\/europace\/euy046","article-title":"European Heart Rhythm Association (EHRA)\/Heart Rhythm Society (HRS)\/Asia Pacific Heart Rhythm Society (APHRS)\/Latin American Heart Rhythm Society (LAHRS) expert consensus on arrhythmias and cognitive function: what is the best practice?","volume":"20","author":"Dagres","year":"2018","journal-title":"Europace"},{"key":"2021122415314915800_cvab147-B177","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.ijcard.2020.08.028","article-title":"Cognitive impairment in patients with atrial fibrillation: implications for outcome in a cohort study","volume":"323","author":"Malavasi","year":"2020","journal-title":"Int J Cardiol"},{"key":"2021122415314915800_cvab147-B178","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-3-030-33330-0_1","article-title":"Frailty: what is it?","volume":"1216","author":"Proietti","year":"2020","journal-title":"Adv Exp Med Biol"},{"key":"2021122415314915800_cvab147-B179","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1093\/ehjqcco\/qcaa002","article-title":"Frailty to predict unplanned hospitalization, stroke, bleeding, and death in atrial fibrillation","volume":"7","author":"Gugganig","year":"2021","journal-title":"Eur Heart J Qual Care Clin Outcomes"},{"key":"2021122415314915800_cvab147-B180","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.ejim.2018.04.018","article-title":"Frailty and atrial fibrillation: a systematic review","volume":"56","author":"Villani","year":"2018","journal-title":"Eur J Intern Med"},{"key":"2021122415314915800_cvab147-B181","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1093\/ageing\/afy180","article-title":"Management of atrial fibrillation for older people with frailty: a systematic review and meta-analysis","volume":"48","author":"Wilkinson","year":"2019","journal-title":"Age Ageing"},{"key":"2021122415314915800_cvab147-B182","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.ahj.2019.01.005","article-title":"Association of frailty and cognitive impairment with benefits of oral anticoagulation in patients with atrial fibrillation","volume":"211","author":"Madhavan","year":"2019","journal-title":"Am Heart J"},{"key":"2021122415314915800_cvab147-B183","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1002\/joa3.12364","article-title":"Application of the simple atrial fibrillation better care pathway for integrated care management in frail patients with atrial fibrillation: a nationwide cohort study","volume":"36","author":"Yang","year":"2020","journal-title":"J Arrhythmia"},{"key":"2021122415314915800_cvab147-B184","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1177\/1535370217744775","article-title":"Biomarkers: delivering on the expectation of molecularly driven, quantitative health","volume":"243","author":"Wilson","year":"2018","journal-title":"Exp Biol Med (Maywood)"},{"key":"2021122415314915800_cvab147-B185","doi-asserted-by":"crossref","first-page":"429","DOI":"10.2459\/JCM.0000000000001103","article-title":"Machine learning and network medicine: a novel approach for precision medicine and personalized therapy in cardiomyopathies","volume":"22","author":"Infante","year":"2020","journal-title":"J Cardiovasc Med (Hagerstown)"},{"key":"2021122415314915800_cvab147-B186","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.ejim.2019.07.017","article-title":"Screening for atrial fibrillation: need for an integrated, structured approach","volume":"67","author":"Boriani","year":"2019","journal-title":"Eur J Intern Med"},{"key":"2021122415314915800_cvab147-B187","doi-asserted-by":"crossref","first-page":"729","DOI":"10.3390\/jcm10040729","article-title":"Clinical factors associated with atrial fibrillation detection on single-time point screening using a hand-held single-lead ECG device","volume":"10","author":"Boriani","year":"2021","journal-title":"J Clin Med"},{"key":"2021122415314915800_cvab147-B188","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1161\/CIRCRESAHA.120.316363","article-title":"Molecular basis of atrial fibrillation pathophysiology and therapy: a translational perspective","volume":"127","author":"Nattel","year":"2020","journal-title":"Circ Res"},{"key":"2021122415314915800_cvab147-B189","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1093\/europace\/euv252","article-title":"The European Network for Translational Research in Atrial Fibrillation (EUTRAF): objectives and initial results","volume":"17","author":"Schotten","year":"2015","journal-title":"Europace"},{"key":"2021122415314915800_cvab147-B190","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.ejim.2020.09.024","article-title":"Mobile health technology-supported atrial fibrillation screening and integrated care: a report from the mAFA-II trial Long-term Extension Cohort","volume":"82","author":"Guo","year":"2020","journal-title":"Eur J Intern Med"},{"key":"2021122415314915800_cvab147-B191","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1002\/clc.23469","article-title":"On-demand mobile health infrastructures to allow comprehensive remote atrial fibrillation and risk factor management through teleconsultation","volume":"43","author":"Hermans","year":"2020","journal-title":"Clin Cardiol"},{"key":"2021122415314915800_cvab147-B192","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1093\/europace\/euaa201","article-title":"Implementation of an on-demand app-based heart rate and rhythm monitoring infrastructure for the management of atrial fibrillation through teleconsultation: teleCheck-AF","volume":"23","author":"Pluymaekers","year":"2020","journal-title":"Europace"},{"key":"2021122415314915800_cvab147-B193","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1111\/j.1365-2753.2010.01461.x","article-title":"W(h)ither complexity? The emperor's new toolkit? Or elucidating the evolution of health systems knowledge?","volume":"16","author":"Martin","year":"2010","journal-title":"J Eval Clin Pract"},{"key":"2021122415314915800_cvab147-B194","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1001\/jamacardio.2017.4665","article-title":"Association of atrial fibrillation clinical phenotypes with treatment patterns and outcomes: a multicenter registry study","volume":"3","author":"Inohara","year":"2018","journal-title":"JAMA Cardiol"}],"container-title":["Cardiovascular Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cardiovascres\/advance-article-pdf\/doi\/10.1093\/cvr\/cvab147\/38427533\/cvab147.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/cardiovascres\/article-pdf\/117\/7\/1\/41927162\/cvab147.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/cardiovascres\/article-pdf\/117\/7\/1\/41927162\/cvab147.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,24]],"date-time":"2021-12-24T10:34:04Z","timestamp":1640342044000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cardiovascres\/article\/117\/7\/1\/6258174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,29]]},"references-count":194,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2021,4,29]]},"published-print":{"date-parts":[[2021,6,16]]}},"URL":"https:\/\/doi.org\/10.1093\/cvr\/cvab147","relation":{},"ISSN":["0008-6363","1755-3245"],"issn-type":[{"value":"0008-6363","type":"print"},{"value":"1755-3245","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,6,15]]},"published":{"date-parts":[[2021,4,29]]}}}