{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:25:02Z","timestamp":1792002302058,"version":"4.4.0"},"reference-count":192,"publisher":"Oxford University Press (OUP)","issue":"14","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"University Funds for basic research","award":["FARB 2019, 2020"],"award-info":[{"award-number":["FARB 2019, 2020"]}]},{"name":"Fundamental Research of excellence in Strategic"},{"DOI":"10.13039\/501100022434","name":"Walloon Excellence in Life Sciences and Biotechnology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022434","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001711","name":"Fonds National de la Recherche Scientifique","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Action de Recherche Concert\u00e9e"},{"name":"Wallonia-Brussels Federation"},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["KFO311 and SFB1470"],"award-info":[{"award-number":["KFO311 and SFB1470"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002428","name":"Austrian Science Fund","doi-asserted-by":"publisher","award":["PRE-CARE ML, I 5898-B to P.R."],"award-info":[{"award-number":["PRE-CARE ML, I 5898-B to P.R."]}],"id":[{"id":"10.13039\/501100002428","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002428","name":"Austrian Science Fund","doi-asserted-by":"publisher","award":["AIR-MI, I 4168-B to P.R."],"award-info":[{"award-number":["AIR-MI, I 4168-B to P.R."]}],"id":[{"id":"10.13039\/501100002428","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001030","name":"Netherlands Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Dekker Senior Clinical Scientist 2019","award":["2019T056"],"award-info":[{"award-number":["2019T056"]}]},{"DOI":"10.13039\/501100005416","name":"Norwegian Research Council","doi-asserted-by":"publisher","award":["91818602 VICI grant"],"award-info":[{"award-number":["91818602 VICI grant"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001030","name":"ZonMW and Heart Foundation","doi-asserted-by":"publisher","award":["95105003"],"award-info":[{"award-number":["95105003"]}],"id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018890","name":"Dutch Cardiovascular Alliance","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018890","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001674","name":"Leducq Foundation","doi-asserted-by":"publisher","award":["20CVD01"],"award-info":[{"award-number":["20CVD01"]}],"id":[{"id":"10.13039\/501100001674","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Human Models","award":["18953"],"award-info":[{"award-number":["18953"]}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["HA 7512\/2-4"],"award-info":[{"award-number":["HA 7512\/2-4"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000085","name":"DFG","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000085","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009584","name":"Clinical Research","doi-asserted-by":"publisher","award":["KFO 311"],"award-info":[{"award-number":["KFO 311"]}],"id":[{"id":"10.13039\/501100009584","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Fundamental Research of excellence in Strategic"},{"DOI":"10.13039\/501100002661","name":"FNRS","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002661","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Wallonia-Brussels Federation"},{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002915","name":"Fondation pour la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002915","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006544","name":"Italian Ministry of Health","doi-asserted-by":"publisher","award":["PNRR-MAD-2022-12376632 and RF-2016-02362988"],"award-info":[{"award-number":["PNRR-MAD-2022-12376632 and RF-2016-02362988"]}],"id":[{"id":"10.13039\/501100006544","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>While chronic heart failure (CHF) treatment has considerably improved patient prognosis and survival, the therapeutic management of acute heart failure (AHF) has remained virtually unchanged in the last decades. This is partly due to the scarcity of pre-clinical models for the pathophysiological assessment and, consequently, the limited knowledge of molecular mechanisms involved in the different AHF phenotypes. This scientific statement outlines the different trajectories from acute to CHF originating from the interaction between aetiology, genetic and environmental factors, and comorbidities. Furthermore, we discuss the potential molecular targets capable of unveiling new therapeutic perspectives to improve the outcome of the acute phase and counteracting the evolution towards CHF.<\/jats:p>","DOI":"10.1093\/cvr\/cvad088","type":"journal-article","created":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T17:13:46Z","timestamp":1698426826000},"page":"2390-2404","source":"Crossref","is-referenced-by-count":9,"title":["Acute heart failure: mechanisms and pre-clinical models\u2014a Scientific Statement of the ESC Working Group on Myocardial Function"],"prefix":"10.1093","volume":"119","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2379-1960","authenticated-orcid":false,"given":"Michele","family":"Ciccarelli","sequence":"first","affiliation":[{"name":"Cardiovascular Research Unit, Department of Medicine and Surgery, University of Salerno , Via Salvador Allende , 84081 Baronissi,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u00eas Falc\u00e3o","family":"Pires","sequence":"additional","affiliation":[{"name":"UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto , Alameda Prof. Hern\u00e2ni Monteiro , 4200-319 Porto,","place":["Portugal"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9341-117X","authenticated-orcid":false,"given":"Johann","family":"Bauersachs","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, Hannover Medical School , Carl-Neuberg-Str. 1 , 30625 Hannover,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0655-7099","authenticated-orcid":false,"given":"Luc","family":"Bertrand","sequence":"additional","affiliation":[{"name":"Pole of Cardiovascular Research, Institut de Recherche Exp\u00e9rimentale et Clinique, Universit\u00e9 Catholique de Louvain , 1200 Brussels ,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Beauloye","sequence":"additional","affiliation":[{"name":"Pole of Cardiovascular Research, Institut de Recherche Exp\u00e9rimentale et Clinique, Universit\u00e9 Catholique de Louvain , 1200 Brussels ,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2815-4469","authenticated-orcid":false,"given":"Dana","family":"Dawson","sequence":"additional","affiliation":[{"name":"Aberdeen Cardiovascular and Diabetes Centre, School of Medicine and Dentistry, University of Aberdeen , Aberdeen ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3053-0008","authenticated-orcid":false,"given":"Nazha","family":"Hamdani","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Forschung und Lehre (IFL), Molecular and Experimental Cardiology, Ruhr University Bochum , 44801 Bochum ,","place":["Germany"]},{"name":"Department of Cardiology, St.Josef-Hospital and Bergmannsheil, Ruhr University Bochum , 44801 Bochum ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Hilfiker-Kleiner","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, Hannover Medical School , Carl-Neuberg Str. 1 , 30625 Hannover,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda W","family":"van Laake","sequence":"additional","affiliation":[{"name":"Division Heart and Lungs, Department of Cardiology and Regenerative Medicine Center, University Medical Center Utrecht , Heidelberglaan 100 , 3584 CX Utrecht,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Lezoualc\u2019h","sequence":"additional","affiliation":[{"name":"Institut des Maladies M\u00e9taboliques et Cardiovasculaires, Inserm, Universit\u00e9 Paul Sabatier, UMR 1297-I2MC , Toulouse ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0801-3773","authenticated-orcid":false,"given":"Wolfgang A","family":"Linke","sequence":"additional","affiliation":[{"name":"Institute of Physiology II, University Hospital M\u00fcnster , Robert-Koch-Str. 27B , M\u00fcnster 48149,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ida G","family":"Lunde","sequence":"additional","affiliation":[{"name":"Division of Diagnostics and Technology (DDT), Akershus University Hospital, and KG Jebsen Center for Cardiac Biomarkers, University of Oslo , Oslo ,","place":["Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter P","family":"Rainer","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine, Medical University of Graz , 8036 Graz ,","place":["Austria"]},{"name":"BioTechMed Graz - University of Graz , 8036 Graz ,","place":["Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Rispoli","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Unit, Department of Medicine and Surgery, University of Salerno , Via Salvador Allende , 84081 Baronissi,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Visco","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Unit, Department of Medicine and Surgery, University of Salerno , Via Salvador Allende , 84081 Baronissi,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albino","family":"Carrizzo","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Unit, Department of Medicine and Surgery, University of Salerno , Via Salvador Allende , 84081 Baronissi,","place":["Italy"]},{"name":"Laboratory of Vascular Physiopathology-I.R.C.C.S. Neuromed , 86077 Pozzilli ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2310-0448","authenticated-orcid":false,"given":"Matteo Dal","family":"Ferro","sequence":"additional","affiliation":[{"name":"Cardiothoracovascular Department, Azienda Sanitaria-Universitaria Giuliano Isontina (ASUGI) , Trieste ,","place":["Italy"]},{"name":"Laboratory of Cardiovascular Biology, The International Centre for Genetic Engineering and Biotechnology , Trieste ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Stolfo","sequence":"additional","affiliation":[{"name":"Cardiothoracovascular Department, Azienda Sanitaria-Universitaria Giuliano Isontina (ASUGI) , Trieste ,","place":["Italy"]},{"name":"Division of Cardiology, Department of Medicine, Karolinska Institutet , Stockholm ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolanda","family":"van der Velden","sequence":"additional","affiliation":[{"name":"Department of Physiology, Amsterdam Cardiovascular Sciences, Amsterdam UMC , Amsterdam ,","place":["Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serena","family":"Zacchigna","sequence":"additional","affiliation":[{"name":"Laboratory of Cardiovascular Biology, The International Centre for Genetic Engineering and Biotechnology , Trieste ,","place":["Italy"]},{"name":"Department of Medicine, Surgery and Health Sciences, University of Trieste , Trieste ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9477-7803","authenticated-orcid":false,"given":"Stephane","family":"Heymans","sequence":"additional","affiliation":[{"name":"Department of Cardiology, CARIM School for Cardiovascular Diseases, Maastricht University Medical Centre , Maastricht ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4360-1511","authenticated-orcid":false,"given":"Thomas","family":"Thum","sequence":"additional","affiliation":[{"name":"Institute of Molecular and Translational Therapeutic Strategies, Hannover Medical School , Hannover ,","place":["Germany"]},{"name":"Fraunhofer Institute for Toxicology and Experimental medicine , Hannover ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo Gabriele","family":"Tocchetti","sequence":"additional","affiliation":[{"name":"Cardio-Oncology Unit, Department of Translational Medical Sciences (DISMET), Center for Basic and Clinical Immunology Research (CISI), Interdepartmental Center of Clinical and Translational Sciences (CIRCET), Interdepartmental Hypertension Research Center (CIRIAPA), Federico II University , Via Pansini 5 , 80131 Naples,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,11,15]]},"reference":[{"key":"2026080909164683500_cvad088-B1","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.jacc.2021.06.040","article-title":"Device therapy in chronic heart failure: JACC state-of-the-art review","volume":"78","author":"Fudim","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"2026080909164683500_cvad088-B2","doi-asserted-by":"crossref","first-page":"874433","DOI":"10.3389\/fcvm.2022.874433","article-title":"A multistep approach to deal with advanced heart failure: a case report on the positive effect of cardiac contractility modulation therapy on pulmonary pressure measured by CardioMEMS","volume":"9","author":"Visco","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"2026080909164683500_cvad088-B3","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1056\/NEJMoa1409077","article-title":"Angiotensin-neprilysin inhibition versus enalapril in heart failure","volume":"371","author":"McMurray","year":"2014","journal-title":"N Engl J Med"},{"key":"2026080909164683500_cvad088-B4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ehjcr\/ytaa205","article-title":"It is easy to see, but it is better to foresee: a case report on the favourable alliance between CardioMEMS and levosimendan","volume":"4","author":"Visco","year":"2020","journal-title":"Eur Heart J Case Rep"},{"key":"2026080909164683500_cvad088-B5","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","article-title":"2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"42","author":"McDonagh","year":"2021","journal-title":"Eur Heart J"},{"key":"2026080909164683500_cvad088-B6","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/nrcardio.2015.134","article-title":"Pathophysiology and clinical evaluation of acute heart failure","volume":"13","author":"Mentz","year":"2016","journal-title":"Nat Rev Cardiol"},{"key":"2026080909164683500_cvad088-B7","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1002\/ejhf.1567","article-title":"Departments involved during the first episode of acute heart failure and subsequent emergency department revisits and rehospitalisations: an outlook through the NOVICA cohort","volume":"21","author":"Miro","year":"2019","journal-title":"Eur J Heart Fail"},{"key":"2026080909164683500_cvad088-B8","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.pcad.2020.04.007","article-title":"Acute heart failure: more questions than answers","volume":"63","author":"Tomasoni","year":"2020","journal-title":"Prog Cardiovasc Dis"},{"key":"2026080909164683500_cvad088-B9","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1093\/eurheartj\/ehl193","article-title":"Euroheart Failure Survey II (EHFS II): a survey on hospitalized acute heart failure patients: description of population","volume":"27","author":"Nieminen","year":"2006","journal-title":"Eur Heart J"},{"key":"2026080909164683500_cvad088-B10","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1002\/ejhf.1492","article-title":"Acute heart failure congestion and perfusion status\u2014impact of the clinical classification on in-hospital and long-term outcomes; insights from the ESC-EORP-HFA Heart Failure Long-Term Registry","volume":"21","author":"Chioncel","year":"2019","journal-title":"Eur J Heart Fail"},{"key":"2026080909164683500_cvad088-B11","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1002\/ejhf.890","article-title":"Clinical phenotypes and outcome of patients hospitalized for acute heart failure: the ESC Heart Failure Long-Term Registry","volume":"19","author":"Chioncel","year":"2017","journal-title":"Eur J Heart Fail"},{"key":"2026080909164683500_cvad088-B12","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.1093\/cvr\/cvab009","article-title":"Reciprocal organ interactions during heart failure: a position paper from the ESC Working Group on Myocardial Function","volume":"117","author":"Ciccarelli","year":"2021","journal-title":"Cardiovasc Res"},{"key":"2026080909164683500_cvad088-B13","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s11897-017-0351-y","article-title":"Acute heart failure: definition, classification and epidemiology","volume":"14","author":"Kurmani","year":"2017","journal-title":"Curr Heart Fail Rep"},{"key":"2026080909164683500_cvad088-B14","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1002\/ejhf.333","article-title":"In-hospital worsening heart failure","volume":"17","author":"Butler","year":"2015","journal-title":"Eur J Heart Fail"},{"key":"2026080909164683500_cvad088-B15","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/s41572-020-0151-7","article-title":"Acute heart failure","volume":"6","author":"Arrigo","year":"2020","journal-title":"Nat Rev Dis Primers"},{"key":"2026080909164683500_cvad088-B16","doi-asserted-by":"crossref","first-page":"e02","DOI":"10.15420\/cfr.2020.20","article-title":"Clinical characteristics of de novo heart failure and acute decompensated chronic heart failure: are they distinctive phenotypes that contribute to different outcomes?","volume":"7","author":"Raffaello","year":"2020","journal-title":"Card Fail Rev"},{"key":"2026080909164683500_cvad088-B17","first-page":"510","article-title":"Acute decompensated heart failure: contemporary medical management","volume":"36","author":"Joseph","year":"2009","journal-title":"Tex Heart Inst J"},{"key":"2026080909164683500_cvad088-B18","doi-asserted-by":"crossref","first-page":"553","DOI":"10.2459\/JCM.0000000000001173","article-title":"Predictors of complications in initially haemodynamically stable patients admitted in a modern coronary care unit","volume":"22","author":"Campanile","year":"2021","journal-title":"J Cardiovasc Med (Hagerstown)"},{"key":"2026080909164683500_cvad088-B19","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0140-6736(18)32484-X","article-title":"Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial","volume":"393","author":"Halliday","year":"2019","journal-title":"Lancet"},{"key":"2026080909164683500_cvad088-B20","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1002\/ehf2.13139","article-title":"Time-sensitive approach in the management of acute heart failure","volume":"8","author":"Shiraishi","year":"2021","journal-title":"ESC Heart Fail"},{"key":"2026080909164683500_cvad088-B21","doi-asserted-by":"crossref","first-page":"e007132","DOI":"10.1161\/CIRCHEARTFAILURE.120.007132","article-title":"Risk profiles in heart failure: baseline, residual, worsening, and advanced heart failure risk","volume":"13","author":"Greene","year":"2020","journal-title":"Circ Heart Fail"},{"key":"2026080909164683500_cvad088-B22","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1016\/j.jacc.2019.08.001","article-title":"2019 ACC expert consensus decision pathway on risk assessment, management, and clinical trajectory of patients hospitalized with heart failure: a report of the American College of Cardiology Solution Set oversight Committee","volume":"74","author":"Hollenberg","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2026080909164683500_cvad088-B23","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1056\/NEJM200101043440103","article-title":"The pathogenesis of acute pulmonary edema associated with hypertension","volume":"344","author":"Gandhi","year":"2001","journal-title":"N Engl J Med"},{"key":"2026080909164683500_cvad088-B24","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.cardfail.2021.01.022","article-title":"Universal definition and classification of heart failure: a report of the Heart Failure Society of America, Heart Failure Association of the European society of Cardiology, Japanese Heart Failure Society and Writing Committee of the Universal Definition of Heart Failure","volume":"27","author":"Bozkurt","year":"2021","journal-title":"J Card Fail"},{"key":"2026080909164683500_cvad088-B25","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s00134-015-4041-5","article-title":"Acute heart failure and cardiogenic shock: a multidisciplinary practical guidance","volume":"42","author":"Mebazaa","year":"2016","journal-title":"Intensive Care Med"},{"key":"2026080909164683500_cvad088-B26","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nrcardio.2016.25","article-title":"Epidemiology and aetiology of heart failure","volume":"13","author":"Ziaeian","year":"2016","journal-title":"Nat Rev Cardiol"},{"key":"2026080909164683500_cvad088-B27","doi-asserted-by":"crossref","first-page":"k5287","DOI":"10.1136\/bmj.k5287","article-title":"Peripartum cardiomyopathy","volume":"364","author":"Honigberg","year":"2019","journal-title":"BMJ"},{"key":"2026080909164683500_cvad088-B28","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1161\/CIRCRESAHA.117.310221","article-title":"Inflammatory cardiomyopathic syndromes","volume":"121","author":"Trachtenberg","year":"2017","journal-title":"Circ Res"},{"key":"2026080909164683500_cvad088-B29","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1038\/s41392-020-00360-y","article-title":"Fulminant myocarditis: a comprehensive review from etiology to treatments and outcomes","volume":"5","author":"Hang","year":"2020","journal-title":"Signal Transduct Target Ther"},{"key":"2026080909164683500_cvad088-B30","doi-asserted-by":"crossref","first-page":"e015502","DOI":"10.1161\/JAHA.119.015502","article-title":"Stunned and hibernating myocardium: where are we nearly 4 decades later?","volume":"9","author":"Kloner","year":"2020","journal-title":"J Am Heart Assoc"},{"key":"2026080909164683500_cvad088-B31","doi-asserted-by":"crossref","first-page":"2549","DOI":"10.1093\/eurheartj\/ehac223","article-title":"Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies","volume":"43","author":"Frantz","year":"2022","journal-title":"Eur Heart J"},{"key":"2026080909164683500_cvad088-B32","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ejim.2008.04.007","article-title":"Hyperuricemia in acute heart failure. More than a simple spectator?","volume":"20","author":"Alimonda","year":"2009","journal-title":"Eur J Intern Med"},{"key":"2026080909164683500_cvad088-B33","doi-asserted-by":"crossref","first-page":"570000","DOI":"10.3389\/fcvm.2020.570000","article-title":"Serum uric acid and left ventricular mass in essential hypertension","volume":"7","author":"Visco","year":"2020","journal-title":"Front Cardiovasc Med"},{"key":"2026080909164683500_cvad088-B34","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.amjmed.2020.08.043","article-title":"Impact of coronavirus disease 2019 (COVID-19) outbreak on acute admissions at the emergency and cardiology departments across Europe","volume":"134","author":"Sokolski","year":"2021","journal-title":"Am J Med"},{"key":"2026080909164683500_cvad088-B35","doi-asserted-by":"crossref","first-page":"82","DOI":"10.15420\/aer.2013.2.2.82","article-title":"What about tachycardia-induced cardiomyopathy?","volume":"2","author":"Ellis","year":"2013","journal-title":"Arrhythm Electrophysiol Rev"},{"key":"2026080909164683500_cvad088-B36","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0002-9343(02)01472-9","article-title":"Tachycardia-induced cardiomyopathy","volume":"114","author":"Umana","year":"2003","journal-title":"Am J Med"},{"key":"2026080909164683500_cvad088-B37","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1002\/ejhf.1461","article-title":"Heart failure in cardiomyopathies: a position paper from the Heart Failure Association of the European Society of Cardiology","volume":"21","author":"Seferovic","year":"2019","journal-title":"Eur J Heart Fail"},{"key":"2026080909164683500_cvad088-B38","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1093\/cvr\/cvy122","article-title":"Complex roads from genotype to phenotype in dilated cardiomyopathy: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology","volume":"114","author":"Bondue","year":"2018","journal-title":"Cardiovasc Res"},{"key":"2026080909164683500_cvad088-B39","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1161\/CIRCULATIONAHA.118.037934","article-title":"Genetic variants associated with cancer therapy-induced cardiomyopathy","volume":"140","author":"Garcia-Pavia","year":"2019","journal-title":"Circulation"},{"key":"2026080909164683500_cvad088-B40","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1016\/j.jacc.2015.07.023","article-title":"Prognostic relevance of gene-environment interactions in patients with dilated cardiomyopathy: applying the MOGE(S) classification","volume":"66","author":"Hazebroek","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"2026080909164683500_cvad088-B41","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1161\/CIRCHEARTFAILURE.112.969246","article-title":"Markers of decongestion, dyspnea relief, and clinical outcomes among patients hospitalized with acute heart failure","volume":"6","author":"Kociol","year":"2013","journal-title":"Circ Heart Fail"},{"key":"2026080909164683500_cvad088-B42","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1007\/s10741-017-9651-2","article-title":"Pathophysiology of acute heart failure syndrome: a knowledge gap","volume":"22","author":"Sabbah","year":"2017","journal-title":"Heart Fail Rev"},{"key":"2026080909164683500_cvad088-B43","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s10741-019-09881-3","article-title":"Role of endothelial dysfunction in heart failure","volume":"25","author":"Zuchi","year":"2020","journal-title":"Heart Fail Rev"},{"key":"2026080909164683500_cvad088-B44","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.cell.2006.12.036","article-title":"A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy","volume":"128","author":"Hilfiker-Kleiner","year":"2007","journal-title":"Cell"},{"key":"2026080909164683500_cvad088-B45","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1172\/JCI64365","article-title":"MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy","volume":"123","author":"Halkein","year":"2013","journal-title":"J Clin Invest"},{"key":"2026080909164683500_cvad088-B46","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0008-6363(03)00397-3","article-title":"Molecular basis of endothelial dysfunction in sepsis","volume":"60","author":"Peters","year":"2003","journal-title":"Cardiovasc Res"},{"key":"2026080909164683500_cvad088-B47","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1136\/heartjnl-2015-308852","article-title":"Microvascular endothelial dysfunction in heart failure with preserved ejection fraction","volume":"102","author":"Lam","year":"2016","journal-title":"Heart"},{"key":"2026080909164683500_cvad088-B48","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1136\/heartjnl-2015-307461","article-title":"The pathophysiology of hypertensive acute heart failure","volume":"101","author":"Viau","year":"2015","journal-title":"Heart"},{"key":"2026080909164683500_cvad088-B49","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1002\/ejhf.1138","article-title":"The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC","volume":"20","author":"Frantz","year":"2018","journal-title":"Eur J Heart Fail"},{"key":"2026080909164683500_cvad088-B50","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1038\/nrcardio.2015.108","article-title":"Viral myocarditis\u2013diagnosis, treatment options, and current controversies","volume":"12","author":"Pollack","year":"2015","journal-title":"Nat Rev Cardiol"},{"key":"2026080909164683500_cvad088-B51","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S1388-9842(03)00104-1","article-title":"Invasive assessment of bacterial endotoxin and inflammatory cytokines in patients with acute heart failure","volume":"5","author":"Peschel","year":"2003","journal-title":"Eur J Heart Fail"},{"key":"2026080909164683500_cvad088-B52","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.1172\/JCI116834","article-title":"Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart","volume":"92","author":"Yokoyama","year":"1993","journal-title":"J Clin Invest"},{"key":"2026080909164683500_cvad088-B53","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1536\/ihj.13-388","article-title":"NLRP3 inflammasome as a novel player in myocardial infarction","volume":"55","author":"Takahashi","year":"2014","journal-title":"Int Heart J"},{"key":"2026080909164683500_cvad088-B54","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1096\/fj.02-0419com","article-title":"TNF-alpha signal transduction in rat neonatal cardiac myocytes: definition of pathways generating from the TNF-alpha receptor","volume":"16","author":"Condorelli","year":"2002","journal-title":"FASEB J"},{"key":"2026080909164683500_cvad088-B55","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1111\/j.1582-4934.2008.00647.x","article-title":"TNF-alpha induces TGF-beta1 expression in lung fibroblasts at the transcriptional level via AP-1 activation","volume":"13","author":"Sullivan","year":"2009","journal-title":"J Cell Mol Med"},{"key":"2026080909164683500_cvad088-B56","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1161\/01.RES.0000047090.08299.D5","article-title":"Tumor necrosis factor-alpha-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosis","volume":"91","author":"Peng","year":"2002","journal-title":"Circ Res"},{"key":"2026080909164683500_cvad088-B57","doi-asserted-by":"crossref","first-page":"20221","DOI":"10.1074\/jbc.M313980200","article-title":"Activation of intrinsic and extrinsic proapoptotic signaling pathways in interleukin-18-mediated human cardiac endothelial cell death","volume":"279","author":"Chandrasekar","year":"2004","journal-title":"J Biol Chem"},{"key":"2026080909164683500_cvad088-B58","doi-asserted-by":"crossref","first-page":"6246","DOI":"10.1182\/blood-2008-11-188375","article-title":"Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1","volume":"113","author":"Woodfin","year":"2009","journal-title":"Blood"},{"key":"2026080909164683500_cvad088-B59","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1161\/01.ATV.18.8.1292","article-title":"Interleukin-1beta induces tissue- and cell type-specific expression of adhesion molecules in vivo","volume":"18","author":"Tamaru","year":"1998","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"2026080909164683500_cvad088-B60","doi-asserted-by":"crossref","first-page":"3228","DOI":"10.1182\/blood.V89.9.3228","article-title":"L-selectin-dependent leukocyte adhesion to microvascular but not to macrovascular endothelial cells of the human coronary system","volume":"89","author":"Zakrzewicz","year":"1997","journal-title":"Blood"},{"key":"2026080909164683500_cvad088-B61","first-page":"134","volume-title":"Acute Heart Failure","author":"Kirkwood","year":"2008"},{"key":"2026080909164683500_cvad088-B62","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1161\/01.CIR.0000156469.96135.0D","article-title":"Interleukin-6 causes myocardial failure and skeletal muscle atrophy in rats","volume":"111","author":"Janssen","year":"2005","journal-title":"Circulation"},{"key":"2026080909164683500_cvad088-B63","doi-asserted-by":"crossref","first-page":"e32","DOI":"10.1016\/S2213-2600(21)00085-0","article-title":"Delayed-onset myocarditis following COVID-19","volume":"9","author":"Bajaj","year":"2021","journal-title":"Lancet Respir Med"},{"key":"2026080909164683500_cvad088-B64","doi-asserted-by":"crossref","first-page":"6151","DOI":"10.1172\/JCI141374","article-title":"Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis","volume":"130","author":"Skendros","year":"2020","journal-title":"J Clin Invest"},{"key":"2026080909164683500_cvad088-B65","doi-asserted-by":"crossref","first-page":"e007485","DOI":"10.1161\/CIRCHEARTFAILURE.120.007485","article-title":"Cardiogenic shock and hyperinflammatory syndrome in young males with COVID-19","volume":"13","author":"Chau","year":"2020","journal-title":"Circ Heart Fail"},{"key":"2026080909164683500_cvad088-B66","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1016\/j.jacc.2022.02.003","article-title":"2022 ACC expert consensus decision pathway on cardiovascular sequelae of COVID-19 in adults: myocarditis and other myocardial involvement, post-acute sequelae of SARS-CoV-2 infection, and return to play: a report of the American College of Cardiology Solution Set Oversight Committee","volume":"79","author":"Writing","year":"2022","journal-title":"J Am Coll Cardiol"},{"key":"2026080909164683500_cvad088-B67","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1124\/jpet.122.001210","article-title":"Cardiovascular implications of microRNAs in coronavirus disease 2019","volume":"384","author":"Izzo","year":"2023","journal-title":"J Pharmacol Exp Ther"},{"key":"2026080909164683500_cvad088-B68","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.thromres.2020.06.029","article-title":"The hypercoagulable state in COVID-19: incidence, pathophysiology, and management","volume":"194","author":"Abou-Ismail","year":"2020","journal-title":"Thromb Res"},{"key":"2026080909164683500_cvad088-B69","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1161\/CIRCRESAHA.111.243360","article-title":"Autoantibodies in heart failure and cardiac dysfunction","volume":"110","author":"Kaya","year":"2012","journal-title":"Circ Res"},{"key":"2026080909164683500_cvad088-B70","doi-asserted-by":"crossref","first-page":"3348","DOI":"10.1002\/ehf2.13376","article-title":"Adaptive anti-myocardial immune response following hospitalization for acute heart failure","volume":"8","author":"Morbach","year":"2021","journal-title":"ESC Heart Fail"},{"key":"2026080909164683500_cvad088-B71","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1080\/14740338.2021.1906860","article-title":"How can we manage the cardiac toxicity of immune checkpoint inhibitors?","volume":"20","author":"Poto","year":"2021","journal-title":"Expert Opin Drug Saf"},{"key":"2026080909164683500_cvad088-B72","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1172\/JCI44583","article-title":"Impaired thymic tolerance to alpha-myosin directs autoimmunity to the heart in mice and humans","volume":"121","author":"Lv","year":"2011","journal-title":"J Clin Invest"},{"key":"2026080909164683500_cvad088-B73","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1126\/science.aav3487","article-title":"Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy","volume":"366","author":"Gil-Cruz","year":"2019","journal-title":"Science"},{"key":"2026080909164683500_cvad088-B74","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1080\/08916930802258651","article-title":"HLA-DQB1* polymorphism and associations with dilated cardiomyopathy, inflammatory dilated cardiomyopathy and myocarditis","volume":"42","author":"Portig","year":"2009","journal-title":"Autoimmunity"},{"key":"2026080909164683500_cvad088-B75","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1002\/ehf2.12945","article-title":"Impact of residual inflammation on myocardial recovery and cardiovascular outcome in Takotsubo patients","volume":"8","author":"Lachmet-Thebaud","year":"2021","journal-title":"ESC Heart Fail"},{"key":"2026080909164683500_cvad088-B76","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1536\/ihj.17-313","article-title":"Catecholamine-Induced senescence of endothelial cells and bone marrow cells promotes cardiac dysfunction in mice","volume":"59","author":"Katsuumi","year":"2018","journal-title":"Int Heart J"},{"key":"2026080909164683500_cvad088-B77","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.jacc.2014.11.025","article-title":"The pathophysiological role of interstitial sodium in heart failure","volume":"65","author":"Nijst","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"2026080909164683500_cvad088-B78","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1038\/nrcardio.2014.125","article-title":"Noncoding RNAs and myocardial fibrosis","volume":"11","author":"Thum","year":"2014","journal-title":"Nat Rev Cardiol"},{"key":"2026080909164683500_cvad088-B79","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/s41467-020-14349-2","article-title":"Preclinical development of a miR-132 inhibitor for heart failure treatment","volume":"11","author":"Foinquinos","year":"2020","journal-title":"Nat Commun"},{"key":"2026080909164683500_cvad088-B80","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1093\/eurheartj\/ehaa898","article-title":"Novel antisense therapy targeting microRNA-132 in patients with heart failure","volume":"42","author":"Taubel","year":"2021","journal-title":"Eur Heart J"},{"key":"2026080909164683500_cvad088-B81","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/j.biocel.2004.09.010","article-title":"Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress","volume":"37","author":"Lee","year":"2005","journal-title":"Int J Biochem Cell Biol"},{"key":"2026080909164683500_cvad088-B82","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.echo.2017.03.016","article-title":"Alterations in cardiac deformation, timing of contraction and relaxation, and early myocardial fibrosis accompany the apparent recovery of acute stress-induced (Takotsubo) cardiomyopathy: an End to the concept of transience","volume":"30","author":"Schwarz","year":"2017","journal-title":"J Am Soc Echocardiogr"},{"key":"2026080909164683500_cvad088-B83","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1161\/CIRCULATIONAHA.117.031841","article-title":"Persistent long-term structural, functional, and metabolic changes after stress-induced (Takotsubo) cardiomyopathy","volume":"137","author":"Scally","year":"2018","journal-title":"Circulation"},{"key":"2026080909164683500_cvad088-B84","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1093\/cvr\/cvab081","article-title":"Metabolic alterations in a rat model of Takotsubo syndrome","volume":"118","author":"Godsman","year":"2022","journal-title":"Cardiovasc Res"},{"key":"2026080909164683500_cvad088-B85","doi-asserted-by":"crossref","first-page":"6571","DOI":"10.1111\/jcmm.15384","article-title":"Targeting mitochondrial fusion and fission proteins for cardioprotection","volume":"24","author":"Hernandez-Resendiz","year":"2020","journal-title":"J Cell Mol Med"},{"key":"2026080909164683500_cvad088-B86","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/nature10230","article-title":"A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter","volume":"476","author":"De Stefani","year":"2011","journal-title":"Nature"},{"key":"2026080909164683500_cvad088-B87","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/nature22082","article-title":"The mitochondrial Na(+)\/Ca(2+) exchanger is essential for Ca(2+) homeostasis and viability","volume":"545","author":"Luongo","year":"2017","journal-title":"Nature"},{"key":"2026080909164683500_cvad088-B88","doi-asserted-by":"crossref","first-page":"102884","DOI":"10.1016\/j.ebiom.2020.102884","article-title":"Mitochondria in acute myocardial infarction and cardioprotection","volume":"57","author":"Ramachandra","year":"2020","journal-title":"EBioMedicine"},{"key":"2026080909164683500_cvad088-B89","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1007\/s10557-020-07096-5","article-title":"Searching for preclinical models of acute decompensated heart failure: a concise narrative overview and a novel swine model","volume":"36","author":"Olivari","year":"2022","journal-title":"Cardiovasc Drugs Ther"},{"key":"2026080909164683500_cvad088-B90","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s10741-018-9762-4","article-title":"Current animal models for the study of congestion in heart failure: an overview","volume":"24","author":"Cops","year":"2019","journal-title":"Heart Fail Rev"},{"key":"2026080909164683500_cvad088-B91","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/1479-5876-12-137","article-title":"Comparison of two preclinical myocardial infarct models: coronary coil deployment versus surgical ligation","volume":"12","author":"Galvez-Monton","year":"2014","journal-title":"J Transl Med"},{"key":"2026080909164683500_cvad088-B92","doi-asserted-by":"crossref","first-page":"H1478","DOI":"10.1152\/ajpheart.00797.2013","article-title":"Characterizing preclinical models of ischemic heart failure: differences between LAD and LCx infarctions","volume":"307","author":"Ishikawa","year":"2014","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2026080909164683500_cvad088-B93","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/S0022-5223(98)70221-1","article-title":"A canine model of dilated cardiomyopathy induced by repetitive intracoronary doxorubicin administration","volume":"115","author":"Toyoda","year":"1998","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2026080909164683500_cvad088-B94","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1046\/j.1525-1594.2003.07133.x","article-title":"Effects of direct mechanical ventricular assistance on regional myocardial function in an animal model of acute heart failure","volume":"27","author":"Kaczmarek","year":"2003","journal-title":"Artif Organs"},{"key":"2026080909164683500_cvad088-B95","first-page":"244","article-title":"Pathogenesis of radiation-induced myocardial fibrosis","volume":"29","author":"Fajardo","year":"1973","journal-title":"Lab Invest"},{"key":"2026080909164683500_cvad088-B96","first-page":"H499","article-title":"Systemic and regional effects of vasopressin and angiotensin in acute left ventricular failure","volume":"260","author":"Arnolda","year":"1991","journal-title":"Am J Physiol"},{"key":"2026080909164683500_cvad088-B97","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1002\/ehf2.13094","article-title":"Transient heart rate reduction improves acute decompensated heart failure-induced left ventricular and coronary dysfunction","volume":"8","author":"Peschanski","year":"2021","journal-title":"ESC Heart Fail"},{"key":"2026080909164683500_cvad088-B98","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.ijcard.2018.12.045","article-title":"Effects of pretreatment with cardiostimulants and beta-blockers on isoprenaline-induced takotsubo-like cardiac dysfunction in rats","volume":"281","author":"Ali","year":"2019","journal-title":"Int J Cardiol"},{"key":"2026080909164683500_cvad088-B99","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1161\/CIRCULATIONAHA.112.111591","article-title":"High levels of circulating epinephrine trigger apical cardiodepression in a beta2-adrenergic receptor\/Gi-dependent manner: a new model of Takotsubo cardiomyopathy","volume":"126","author":"Paur","year":"2012","journal-title":"Circulation"},{"key":"2026080909164683500_cvad088-B100","first-page":"20","article-title":"Doxorubicin cardiotoxicity in the rat: an in vivo characterization","volume":"46","author":"Hayward","year":"2007","journal-title":"J Am Assoc Lab Anim Sci"},{"key":"2026080909164683500_cvad088-B101","doi-asserted-by":"crossref","first-page":"12479","DOI":"10.3390\/ijms232012479","article-title":"Early doxorubicin myocardial injury: inflammatory, oxidative stress, and apoptotic role of galectin-3","volume":"23","author":"Al-Salam","year":"2022","journal-title":"Int J Mol Sci"},{"key":"2026080909164683500_cvad088-B102","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1016\/j.ijcard.2012.12.092","article-title":"Novel rat model reveals important roles of beta-adrenoreceptors in stress-induced cardiomyopathy","volume":"168","author":"Shao","year":"2013","journal-title":"Int J Cardiol"},{"key":"2026080909164683500_cvad088-B103","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0735-1097(96)00592-X","article-title":"Tachycardia-induced cardiomyopathy: a review of animal models and clinical studies","volume":"29","author":"Shinbane","year":"1997","journal-title":"J Am Coll Cardiol"},{"key":"2026080909164683500_cvad088-B104","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.vascn.2019.02.001","article-title":"A mouse model of heart failure exhibiting pulmonary edema and pleural effusion: useful for testing new drugs","volume":"96","author":"Ma","year":"2019","journal-title":"J Pharmacol Toxicol Methods"},{"key":"2026080909164683500_cvad088-B105","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.cardiores.2004.10.014","article-title":"Mouse model of post-infarct ventricular rupture: time course, strain- and gender-dependency, tensile strength, and histopathology","volume":"65","author":"Gao","year":"2005","journal-title":"Cardiovasc Res"},{"key":"2026080909164683500_cvad088-B106","doi-asserted-by":"crossref","first-page":"2414","DOI":"10.1093\/cvr\/cvab290","article-title":"A mouse model of cardiogenic shock","volume":"117","author":"Wang","year":"2021","journal-title":"Cardiovasc Res"},{"key":"2026080909164683500_cvad088-B107","doi-asserted-by":"crossref","first-page":"3820591","DOI":"10.1155\/2022\/3820591","article-title":"Preparation and evaluation of animal models of cardiotoxicity in antineoplastic therapy","volume":"2022","author":"Meng","year":"2022","journal-title":"Oxid Med Cell Longev"},{"key":"2026080909164683500_cvad088-B108","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.ijcard.2019.01.064","article-title":"What can we learn from animal models of Takotsubo syndrome?","volume":"281","author":"Angelini","year":"2019","journal-title":"Int J Cardiol"},{"key":"2026080909164683500_cvad088-B109","first-page":"H722","article-title":"Chronic heart failure induced by coronary artery ligation in Lewis inbred rats","volume":"272","author":"Liu","year":"1997","journal-title":"Am J Physiol"},{"key":"2026080909164683500_cvad088-B110","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.cmet.2015.07.008","article-title":"Reversal of mitochondrial transhydrogenase causes oxidative stress in heart failure","volume":"22","author":"Nickel","year":"2015","journal-title":"Cell Metab"},{"key":"2026080909164683500_cvad088-B111","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1056\/NEJMra0800239","article-title":"Biomarkers in heart failure","volume":"358","author":"Braunwald","year":"2008","journal-title":"N Engl J Med"},{"key":"2026080909164683500_cvad088-B112","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1056\/NEJMoa020233","article-title":"Breathing not properly multinational study I. Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure","volume":"347","author":"Maisel","year":"2002","journal-title":"N Engl J Med"},{"key":"2026080909164683500_cvad088-B113","first-page":"e895","article-title":"2022 AHA\/ACC\/HFSA guideline for the management of heart failure: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"145","author":"Heidenreich","year":"2022","journal-title":"Circulation"},{"key":"2026080909164683500_cvad088-B114","doi-asserted-by":"crossref","first-page":"e006541","DOI":"10.1161\/CIRCHEARTFAILURE.119.006541","article-title":"Comparison of BNP and NT-proBNP in patients with heart failure and reduced ejection fraction","volume":"13","author":"Rorth","year":"2020","journal-title":"Circ Heart Fail"},{"key":"2026080909164683500_cvad088-B115","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.hfc.2017.08.007","article-title":"Troponin in heart failure","volume":"14","author":"Shah","year":"2018","journal-title":"Heart Fail Clin"},{"key":"2026080909164683500_cvad088-B116","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.cca.2019.10.029","article-title":"sST2 as a value-added biomarker in heart failure","volume":"501","author":"Lotierzo","year":"2020","journal-title":"Clin Chim Acta"},{"key":"2026080909164683500_cvad088-B117","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00392-012-0500-y","article-title":"Galectin-3 is an independent marker for ventricular remodeling and mortality in patients with chronic heart failure","volume":"102","author":"Lok","year":"2013","journal-title":"Clin Res Cardiol"},{"key":"2026080909164683500_cvad088-B118","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1002\/ejhf.2346","article-title":"Circulating heart failure biomarkers beyond natriuretic peptides: review from the Biomarker Study Group of the Heart Failure Association (HFA), European Society of Cardiology (ESC)","volume":"23","author":"Meijers","year":"2021","journal-title":"Eur J Heart Fail"},{"key":"2026080909164683500_cvad088-B119","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1111\/j.1527-5299.2006.05595.x","article-title":"Inflammatory biomarkers in heart failure","volume":"12","author":"Petersen","year":"2006","journal-title":"Congest Heart Fail"},{"key":"2026080909164683500_cvad088-B120","doi-asserted-by":"crossref","first-page":"2442","DOI":"10.1016\/j.bbadis.2012.12.014","article-title":"Biomarkers and diagnostics in heart failure","volume":"1832","author":"Gaggin","year":"2013","journal-title":"Biochim Biophys Acta"},{"key":"2026080909164683500_cvad088-B121","doi-asserted-by":"crossref","first-page":"893","DOI":"10.2217\/bmm-2017-0160","article-title":"Procalcitonin in heart failure: hic et nunc","volume":"11","author":"Cvetinovic","year":"2017","journal-title":"Biomark Med"},{"key":"2026080909164683500_cvad088-B122","doi-asserted-by":"crossref","first-page":"e146343","DOI":"10.1172\/JCI146343","article-title":"Targeting the ASMase\/S1P pathway protects from sortilin-evoked vascular damage in hypertension","volume":"132","author":"Di Pietro","year":"2022","journal-title":"J Clin Invest"},{"key":"2026080909164683500_cvad088-B123","doi-asserted-by":"crossref","first-page":"3850","DOI":"10.3390\/ijms22083850","article-title":"Endothelial dysfunction, inflammation and coronary artery disease: potential biomarkers and promising therapeutical approaches","volume":"22","author":"Medina-Leyte","year":"2021","journal-title":"Int J Mol Sci"},{"key":"2026080909164683500_cvad088-B124","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.amjcard.2006.04.018","article-title":"Plasma myeloperoxidase levels in patients with chronic heart failure","volume":"98","author":"Tang","year":"2006","journal-title":"Am J Cardiol"},{"key":"2026080909164683500_cvad088-B125","doi-asserted-by":"crossref","first-page":"2380","DOI":"10.1161\/CIRCULATIONAHA.113.006855","article-title":"Heart failure with recovered ejection fraction: clinical description, biomarkers, and outcomes","volume":"129","author":"Basuray","year":"2014","journal-title":"Circulation"},{"key":"2026080909164683500_cvad088-B126","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1016\/j.jacc.2012.06.062","article-title":"Myocardial recovery and the failing heart: myth, magic, or molecular target?","volume":"60","author":"Mann","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"2026080909164683500_cvad088-B127","first-page":"60","article-title":"The role of oxidative stress in cardiovascular aging and cardiovascular diseases","volume":"11","author":"Izzo","year":"2021","journal-title":"Life (Basel)"},{"key":"2026080909164683500_cvad088-B128","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.freeradbiomed.2020.12.026","article-title":"Discovery of new therapeutic redox targets for cardioprotection against ischemia\/reperfusion injury and heart failure","volume":"163","author":"Daiber","year":"2021","journal-title":"Free Radic Biol Med"},{"key":"2026080909164683500_cvad088-B129","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1177\/10742484211042706","article-title":"The role of sGC stimulators and activators in heart failure with reduced ejection fraction","volume":"26","author":"Cordwin","year":"2021","journal-title":"J Cardiovasc Pharmacol Ther"},{"key":"2026080909164683500_cvad088-B130","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1056\/NEJMoa1915928","article-title":"Vericiguat in patients with heart failure and reduced ejection fraction","volume":"382","author":"Armstrong","year":"2020","journal-title":"N Engl J Med"},{"key":"2026080909164683500_cvad088-B131","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1002\/ejhf.1366","article-title":"Adrenomedullin in heart failure: pathophysiology and therapeutic application","volume":"21","author":"Voors","year":"2019","journal-title":"Eur J Heart Fail"},{"key":"2026080909164683500_cvad088-B132","first-page":"1437","article-title":"Mesenchymal stem cells overexpressing adrenomedullin improve heart function through antifibrotic action in rats experiencing heart failure","volume":"17","author":"Li","year":"2018","journal-title":"Mol Med Rep"},{"key":"2026080909164683500_cvad088-B133","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/sj.bjp.0706771","article-title":"Adrenomedullin acts via nitric oxide and peroxynitrite to protect against myocardial ischaemia-induced arrhythmias in anaesthetized rats","volume":"148","author":"Looi","year":"2006","journal-title":"Br J Pharmacol"},{"key":"2026080909164683500_cvad088-B134","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1161\/01.CIR.0000136085.34185.83","article-title":"Adrenomedullin administration immediately after myocardial infarction ameliorates progression of heart failure in rats","volume":"110","author":"Nakamura","year":"2004","journal-title":"Circulation"},{"key":"2026080909164683500_cvad088-B135","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1161\/01.CIR.0000109214.30211.7C","article-title":"Adrenomedullin infusion attenuates myocardial ischemia\/reperfusion injury through the phosphatidylinositol 3-kinase\/Akt-dependent pathway","volume":"109","author":"Okumura","year":"2004","journal-title":"Circulation"},{"key":"2026080909164683500_cvad088-B136","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1097\/FJC.0b013e3181f15b45","article-title":"The first clinical pilot study of intravenous adrenomedullin administration in patients with acute myocardial infarction","volume":"56","author":"Kataoka","year":"2010","journal-title":"J Cardiovasc Pharmacol"},{"key":"2026080909164683500_cvad088-B137","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1253\/circj.CJ-08-0487","article-title":"Effects of long-term intravenous administration of adrenomedullin (AM) plus hANP therapy in acute decompensated heart failure: a pilot study","volume":"73","author":"Nishikimi","year":"2009","journal-title":"Circ J"},{"key":"2026080909164683500_cvad088-B138","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1161\/01.CIR.101.5.498","article-title":"Hemodynamic, renal, and hormonal effects of adrenomedullin infusion in patients with congestive heart failure","volume":"101","author":"Nagaya","year":"2000","journal-title":"Circulation"},{"key":"2026080909164683500_cvad088-B139","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1161\/01.CIR.95.5.1214","article-title":"Potent and long-lasting vasodilatory effects of adrenomedullin in humans. Comparisons between normal subjects and patients with chronic heart failure","volume":"95","author":"Nakamura","year":"1997","journal-title":"Circulation"},{"key":"2026080909164683500_cvad088-B140","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1097\/SHK.0000000000001103","article-title":"Vascular effects of adrenomedullin and the anti-adrenomedullin antibody adrecizumab in sepsis","volume":"50","author":"Geven","year":"2018","journal-title":"Shock"},{"key":"2026080909164683500_cvad088-B141","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.ejphar.2016.02.028","article-title":"ORM-3819 promotes cardiac contractility through Ca(2+) sensitization in combination with selective PDE III inhibition, a novel approach to inotropy","volume":"775","author":"Nagy","year":"2016","journal-title":"Eur J Pharmacol"},{"key":"2026080909164683500_cvad088-B142","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/FJC.0000000000000700","article-title":"The novel inodilator ORM-3819 relaxes isolated porcine coronary arteries: role of voltage-gated potassium channel activation","volume":"74","author":"Marton","year":"2019","journal-title":"J Cardiovasc Pharmacol"},{"key":"2026080909164683500_cvad088-B143","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1056\/NEJMoa1801291","article-title":"Effects of serelaxin in patients with acute heart failure","volume":"381","author":"Metra","year":"2019","journal-title":"N Engl J Med"},{"key":"2026080909164683500_cvad088-B144","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1111\/bph.13523","article-title":"The actions of relaxin on the human cardiovascular system","volume":"174","author":"Sarwar","year":"2017","journal-title":"Br J Pharmacol"},{"key":"2026080909164683500_cvad088-B145","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1002\/ejhf.678","article-title":"Metabolic support for the heart: complementary therapy for heart failure?","volume":"18","author":"Heggermont","year":"2016","journal-title":"Eur J Heart Fail"},{"key":"2026080909164683500_cvad088-B146","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1161\/CIRCULATIONAHA.108.778019","article-title":"Trimetazidine, a metabolic modulator, has cardiac and extracardiac benefits in idiopathic dilated cardiomyopathy","volume":"118","author":"Tuunanen","year":"2008","journal-title":"Circulation"},{"key":"2026080909164683500_cvad088-B147","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.ijcard.2012.09.123","article-title":"Effect of partial fatty acid oxidation inhibition with trimetazidine on mortality and morbidity in heart failure: results from an international multicentre retrospective cohort study","volume":"163","author":"Fragasso","year":"2013","journal-title":"Int J Cardiol"},{"key":"2026080909164683500_cvad088-B148","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.jacc.2006.03.060","article-title":"A randomized clinical trial of trimetazidine, a partial free fatty acid oxidation inhibitor, in patients with heart failure","volume":"48","author":"Fragasso","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"2026080909164683500_cvad088-B149","doi-asserted-by":"crossref","first-page":"e0179509","DOI":"10.1371\/journal.pone.0179509","article-title":"Trimetazidine therapy for diabetic mouse hearts subjected to ex vivo acute heart failure","volume":"12","author":"Breedt","year":"2017","journal-title":"PLoS One"},{"key":"2026080909164683500_cvad088-B150","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1016\/j.jacc.2019.02.051","article-title":"Cardiac calcitropes, myotropes, and mitotropes: JACC review topic of the week","volume":"73","author":"Psotka","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2026080909164683500_cvad088-B151","doi-asserted-by":"crossref","first-page":"e021949","DOI":"10.1161\/JAHA.121.021949","article-title":"SGLT2 Inhibition on cardiac mitochondrial function: searching for a sweet spot","volume":"10","author":"Sawicki","year":"2021","journal-title":"J Am Heart Assoc"},{"key":"2026080909164683500_cvad088-B152","doi-asserted-by":"crossref","first-page":"e019995","DOI":"10.1161\/JAHA.120.019995","article-title":"Effects of sodium-glucose linked transporter 2 inhibition with ertugliflozin on mitochondrial function, energetics, and metabolic gene expression in the presence and absence of diabetes Mellitus in mice","volume":"10","author":"Croteau","year":"2021","journal-title":"J Am Heart Assoc"},{"key":"2026080909164683500_cvad088-B153","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1038\/s41591-021-01659-1","article-title":"The SGLT2 inhibitor empagliflozin in patients hospitalized for acute heart failure: a multinational randomized trial","volume":"28","author":"Voors","year":"2022","journal-title":"Nat Med"},{"key":"2026080909164683500_cvad088-B154","doi-asserted-by":"crossref","first-page":"4370","DOI":"10.1002\/ehf2.13760","article-title":"A year in heart failure: an update of recent findings","volume":"8","author":"Stretti","year":"2021","journal-title":"ESC Heart Fail"},{"key":"2026080909164683500_cvad088-B155","doi-asserted-by":"crossref","first-page":"2415","DOI":"10.1161\/ATVBAHA.113.302262","article-title":"Endothelial G protein-coupled receptor kinase 2 regulates vascular homeostasis through the control of free radical oxygen species","volume":"33","author":"Ciccarelli","year":"2013","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"2026080909164683500_cvad088-B156","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1161\/CIRCULATIONAHA.110.988642","article-title":"G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia","volume":"123","author":"Ciccarelli","year":"2011","journal-title":"Circulation"},{"key":"2026080909164683500_cvad088-B157","doi-asserted-by":"crossref","first-page":"167","DOI":"10.3390\/cells10010167","article-title":"The metabolic role of GRK2 in insulin resistance and associated conditions","volume":"10","author":"Sorriento","year":"2021","journal-title":"Cells"},{"key":"2026080909164683500_cvad088-B158","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.3390\/ijms20061492","article-title":"Antidiabetic and cardioprotective effects of pharmacological inhibition of GRK2 in db\/db mice","volume":"20","author":"Cipolletta","year":"2019","journal-title":"Int J Mol Sci"},{"key":"2026080909164683500_cvad088-B159","doi-asserted-by":"crossref","first-page":"64","DOI":"10.3389\/fphar.2019.00064","article-title":"GRKs and beta-arrestins: \u201cgatekeepers\u201d of mitochondrial function in the failing heart","volume":"10","author":"Sorriento","year":"2019","journal-title":"Front Pharmacol"},{"key":"2026080909164683500_cvad088-B160","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1002\/ehf2.12706","article-title":"Pharmacological inhibition of GRK2 improves cardiac metabolism and function in experimental heart failure","volume":"7","author":"Ciccarelli","year":"2020","journal-title":"ESC Heart Fail"},{"key":"2026080909164683500_cvad088-B161","doi-asserted-by":"crossref","first-page":"3879","DOI":"10.3390\/ijms20163879","article-title":"Inflammation and cardiovascular diseases: the most recent findings","volume":"20","author":"Sorriento","year":"2019","journal-title":"Int J Mol Sci"},{"key":"2026080909164683500_cvad088-B162","doi-asserted-by":"crossref","first-page":"48","DOI":"10.3389\/fcvm.2016.00048","article-title":"\u201cFreeze, don't move\u201d: how to arrest a suspect in heart failure\u2014a review on available GRK2 inhibitors","volume":"3","author":"Sorriento","year":"2016","journal-title":"Front Cardiovasc Med"},{"key":"2026080909164683500_cvad088-B163","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1089\/ars.2015.6430","article-title":"Pharmacology and clinical drug candidates in redox medicine","volume":"23","author":"Dao","year":"2015","journal-title":"Antioxid Redox Signal"},{"key":"2026080909164683500_cvad088-B164","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1096\/fj.05-3718com","article-title":"Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury","volume":"19","author":"Adlam","year":"2005","journal-title":"FASEB J"},{"key":"2026080909164683500_cvad088-B165","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.ejphar.2015.04.009","article-title":"Differences in the profile of protection afforded by TRO40303 and mild hypothermia in models of cardiac ischemia\/reperfusion injury","volume":"760","author":"Hansson","year":"2015","journal-title":"Eur J Pharmacol"},{"key":"2026080909164683500_cvad088-B166","doi-asserted-by":"crossref","first-page":"2549","DOI":"10.1113\/jphysiol.2013.268680","article-title":"Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice","volume":"592","author":"Gioscia-Ryan","year":"2014","journal-title":"J Physiol"},{"key":"2026080909164683500_cvad088-B167","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1152\/japplphysiol.00822.2015","article-title":"Pharmacological targeting of mitochondrial reactive oxygen species counteracts diaphragm weakness in chronic heart failure","volume":"120","author":"Laitano","year":"2016","journal-title":"J Appl Physiol (1985)"},{"key":"2026080909164683500_cvad088-B168","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1161\/CIRCRESAHA.115.303062","article-title":"Inhibiting mitochondrial Na+\/Ca2+ exchange prevents sudden death in a Guinea pig model of heart failure","volume":"115","author":"Liu","year":"2014","journal-title":"Circ Res"},{"key":"2026080909164683500_cvad088-B169","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1161\/CIRCRESAHA.118.312708","article-title":"Mitochondrial ROS drive sudden cardiac death and chronic proteome remodeling in heart failure","volume":"123","author":"Dey","year":"2018","journal-title":"Circ Res"},{"key":"2026080909164683500_cvad088-B170","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1161\/CIRCHEARTFAILURE.113.001062","article-title":"Oxidative post-translational modifications develop LONP1 dysfunction in pressure overload heart failure","volume":"7","author":"Hoshino","year":"2014","journal-title":"Circ Heart Fail"},{"key":"2026080909164683500_cvad088-B171","first-page":"349","article-title":"Low STAT3 expression sensitizes to toxic effects of beta-adrenergic receptor stimulation in peripartum cardiomyopathy","volume":"38","author":"Stapel","year":"2017","journal-title":"Eur Heart J"},{"key":"2026080909164683500_cvad088-B172","doi-asserted-by":"crossref","first-page":"3375","DOI":"10.1002\/ehf2.13412","article-title":"Perhexiline treatment improves toxic effects of beta-adrenergic receptor stimulation in experimental peripartum cardiomyopathy","volume":"8","author":"Pfeffer","year":"2021","journal-title":"ESC Heart Fail"},{"key":"2026080909164683500_cvad088-B173","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s00395-012-0273-5","article-title":"Emerging beneficial roles of sirtuins in heart failure","volume":"107","author":"Tanno","year":"2012","journal-title":"Basic Res Cardiol"},{"key":"2026080909164683500_cvad088-B174","doi-asserted-by":"crossref","first-page":"8706","DOI":"10.3390\/ijms21228706","article-title":"A novel promising frontier for human health: the beneficial effects of nutraceuticals in cardiovascular diseases","volume":"21","author":"Carrizzo","year":"2020","journal-title":"Int J Mol Sci"},{"key":"2026080909164683500_cvad088-B175","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.fct.2013.07.021","article-title":"Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases","volume":"61","author":"Carrizzo","year":"2013","journal-title":"Food Chem Toxicol"},{"key":"2026080909164683500_cvad088-B176","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1126\/science.1231097","article-title":"Evidence for a common mechanism of SIRT1 regulation by allosteric activators","volume":"339","author":"Hubbard","year":"2013","journal-title":"Science"},{"key":"2026080909164683500_cvad088-B177","doi-asserted-by":"crossref","first-page":"104308","DOI":"10.1155\/2013\/104308","article-title":"Nrf2 and cardiovascular defense","volume":"2013","author":"Howden","year":"2013","journal-title":"Oxid Med Cell Longev"},{"key":"2026080909164683500_cvad088-B178","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1002\/ejhf.2204","article-title":"The multifaceted mechanisms of nitroxyl in heart failure: inodilator or \u2018only\u2019 vasodilator?","volume":"23","author":"Tocchetti","year":"2021","journal-title":"Eur J Heart Fail"},{"key":"2026080909164683500_cvad088-B179","doi-asserted-by":"crossref","first-page":"3626","DOI":"10.1093\/eurheartj\/ehy600","article-title":"Treatments targeting inotropy","volume":"40","author":"Maack","year":"2019","journal-title":"Eur Heart J"},{"key":"2026080909164683500_cvad088-B180","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1002\/ejhf.897","article-title":"A phase 2a dose-escalation study of the safety, tolerability, pharmacokinetics and haemodynamic effects of BMS-986231 in hospitalized patients with heart failure with reduced ejection fraction","volume":"19","author":"Tita","year":"2017","journal-title":"Eur J Heart Fail"},{"key":"2026080909164683500_cvad088-B181","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1161\/CIRCRESAHA.119.313682","article-title":"Leveraging signaling pathways to treat heart failure with reduced ejection fraction","volume":"124","author":"Pinilla-Vera","year":"2019","journal-title":"Circ Res"},{"key":"2026080909164683500_cvad088-B182","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.jchf.2020.10.012","article-title":"Effects of a novel nitroxyl donor in acute heart failure: the STAND-UP AHF Study","volume":"9","author":"Felker","year":"2021","journal-title":"JACC Heart failure"},{"key":"2026080909164683500_cvad088-B183","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.3390\/ijms20071599","article-title":"NFkappab is a key player in the crosstalk between inflammation and cardiovascular diseases","volume":"20","author":"Fiordelisi","year":"2019","journal-title":"Int J Mol Sci"},{"key":"2026080909164683500_cvad088-B184","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1161\/CIRCRESAHA.116.302317","article-title":"Innate immunity and the failing heart: the cytokine hypothesis revisited","volume":"116","author":"Mann","year":"2015","journal-title":"Circ Res"},{"key":"2026080909164683500_cvad088-B185","doi-asserted-by":"crossref","first-page":"3099","DOI":"10.1016\/j.jacc.2019.10.038","article-title":"Cardiovascular events among adults treated with chimeric antigen receptor T-cells (CAR-T)","volume":"74","author":"Alvi","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2026080909164683500_cvad088-B186","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/j.annonc.2020.05.005","article-title":"Tocilizumab for refractory severe immune checkpoint inhibitor-associated myocarditis","volume":"31","author":"Doms","year":"2020","journal-title":"Ann Oncol"},{"key":"2026080909164683500_cvad088-B187","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s40425-017-0300-z","article-title":"Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group","volume":"5","author":"Puzanov","year":"2017","journal-title":"J Immunother Cancer"},{"key":"2026080909164683500_cvad088-B188","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1056\/NEJMc1903064","article-title":"Alemtuzumab for immune-related myocarditis due to PD-1 therapy","volume":"380","author":"Esfahani","year":"2019","journal-title":"N Engl J Med"},{"key":"2026080909164683500_cvad088-B189","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1056\/NEJMc1901677","article-title":"Abatacept for severe immune checkpoint inhibitor-associated myocarditis","volume":"380","author":"Salem","year":"2019","journal-title":"N Engl J Med"},{"key":"2026080909164683500_cvad088-B190","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1158\/2159-8290.CD-20-0856","article-title":"A genetic mouse model recapitulates immune checkpoint inhibitor-associated myocarditis and supports a mechanism-based therapeutic intervention","volume":"11","author":"Wei","year":"2021","journal-title":"Cancer Discov"},{"key":"2026080909164683500_cvad088-B191","doi-asserted-by":"crossref","first-page":"3016","DOI":"10.1093\/cvr\/cvab370","article-title":"Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Feart","volume":"118","author":"van der Velden","year":"2022","journal-title":"Cardiovasc Res"},{"key":"2026080909164683500_cvad088-B192","doi-asserted-by":"crossref","first-page":"6569","DOI":"10.2174\/0929867328666201218122633","article-title":"Artificial intelligence as a business partner in cardiovascular precision medicine: an emerging approach for disease detection and treatment optimization","volume":"28","author":"Visco","year":"2021","journal-title":"Curr Med Chem"}],"container-title":["Cardiovascular Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/cardiovascres\/article-pdf\/119\/14\/2390\/60907783\/cvad088.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/cardiovascres\/article-pdf\/119\/14\/2390\/60907783\/cvad088.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T13:17:41Z","timestamp":1786281461000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cardiovascres\/article\/119\/14\/2390\/7421377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":192,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2023,11,15]]},"published-print":{"date-parts":[[2023,11,15]]}},"URL":"https:\/\/doi.org\/10.1093\/cvr\/cvad088","relation":{},"ISSN":["0008-6363","1755-3245"],"issn-type":[{"value":"0008-6363","type":"print"},{"value":"1755-3245","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,10]]},"published":{"date-parts":[[2023,10]]}}}