{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T18:38:32Z","timestamp":1792521512000,"version":"4.5.0"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovascular Research"],"published-print":{"date-parts":[[2011,5,1]]},"DOI":"10.1093\/cvr\/cvq376","type":"journal-article","created":{"date-parts":[[2010,11,30]],"date-time":"2010-11-30T05:04:52Z","timestamp":1291093492000},"page":"276-284","source":"Crossref","is-referenced-by-count":302,"title":["Sirt1 acts in association with PPAR\u00a0 to protect the heart from hypertrophy, metabolic dysregulation, and inflammation"],"prefix":"10.1093","volume":"90","author":[{"given":"A.","family":"Planavila","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Iglesias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Giralt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Villarroya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2010,11,29]]},"reference":[{"issue":"1","key":"1_6230838","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1007\/s004240050739","volume":"437","author":"van Bilsen","year":"1998","journal-title":"Pfl  gers Archiv : European journal of physiology","ISSN":"https:\/\/id.crossref.org\/issn\/0031-6768","issn-type":"print"},{"issue":"7121","key":"2_23129053","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1038\/nature05486","volume":"444","author":"Guarente","year":"2006","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"6","key":"3_23135956","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1016\/j.cell.2006.11.013","volume":"127","author":"Lagouge","year":"2006","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"6993","key":"4_18226604","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1038\/nature02583","volume":"429","author":"Picard","year":"2004","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"5-6","key":"5_36933028","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1242\/dmm.004655","volume":"3","year":"2010","journal-title":"Disease Models & Mechanisms","ISSN":"https:\/\/id.crossref.org\/issn\/1754-8403","issn-type":"print"},{"issue":"4","key":"6_18690681","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1016\/j.cardiores.2004.11.011","volume":"65","author":"Planavila","year":"2005","journal-title":"Cardiovascular Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-6363","issn-type":"print"},{"issue":"9","key":"7_17779165","doi-asserted-by":"publisher","first-page":"4187","DOI":"10.1210\/en.2002-0217","volume":"144","year":"2003","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"issue":"4","key":"8_34560402","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.cmet.2009.02.006","volume":"9","author":"Purushotham","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1550-4131","issn-type":"print"},{"issue":"7","key":"9_16872637","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1016\/S0022-2275(20)37421-6","volume":"38","author":"de Vries","year":"1997","journal-title":"The Journal of Lipid Research","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2275","issn-type":"print"},{"issue":"33","key":"10_35113720","doi-asserted-by":"publisher","first-page":"21872","DOI":"10.1074\/jbc.M109.022749","volume":"284","year":"2009","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"17","key":"11_19574151","doi-asserted-by":"publisher","first-page":"17464","DOI":"10.1074\/jbc.M414220200","volume":"280","year":"2005","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"43","key":"12_31702780","doi-asserted-by":"publisher","first-page":"29109","DOI":"10.1074\/jbc.M802143200","volume":"283","year":"2008","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"2","key":"13_32613716","doi-asserted-by":"publisher","first-page":"344","DOI":"10.2337\/db07-1795","volume":"58","year":"2009","journal-title":"Diabetes","ISSN":"https:\/\/id.crossref.org\/issn\/0012-1797","issn-type":"print"},{"issue":"12","key":"14_18224634","doi-asserted-by":"publisher","first-page":"2369","DOI":"10.1038\/sj.emboj.7600244","volume":"23","year":"2004","journal-title":"The EMBO Journal","ISSN":"https:\/\/id.crossref.org\/issn\/0261-4189","issn-type":"print"},{"issue":"5","key":"15_32968665","doi-asserted-by":"publisher","first-page":"1363","DOI":"10.1128\/MCB.00705-08","volume":"29","year":"2009","journal-title":"Molecular and Cellular Biology","ISSN":"https:\/\/id.crossref.org\/issn\/0270-7306","issn-type":"print"},{"key":"16_34039216","first-page":"91","volume":"160","year":"2002","ISSN":"https:\/\/id.crossref.org\/issn\/1879-1484","issn-type":"print"},{"issue":"45","key":"17_6350521","doi-asserted-by":"publisher","first-page":"32048","DOI":"10.1074\/jbc.274.45.32048","volume":"274","author":"Delerive","year":"1999","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"7029","key":"18_18714057","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1038\/nature03354","volume":"434","author":"Rodgers","year":"2005","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"10","key":"19_28391856","doi-asserted-by":"publisher","first-page":"1512","DOI":"10.1161\/01.RES.0000267723.65696.4a","volume":"100","year":"2007","journal-title":"Circulation Research","ISSN":"https:\/\/id.crossref.org\/issn\/0009-7330","issn-type":"print"},{"issue":"10","key":"20_18517886","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1161\/01.RES.0000147557.75257.ff","volume":"95","year":"2004","journal-title":"Circulation Research","ISSN":"https:\/\/id.crossref.org\/issn\/0009-7330","issn-type":"print"},{"issue":"11","key":"21_36325997","doi-asserted-by":"publisher","first-page":"8340","DOI":"10.1074\/jbc.M109.088682","volume":"285","year":"2010","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"3","key":"22_37203242","doi-asserted-by":"publisher","first-page":"196","DOI":"10.3109\/08037051.2010.481808","volume":"19","author":"Biala","year":"2010","journal-title":"Blood pressure","ISSN":"https:\/\/id.crossref.org\/issn\/0803-7051","issn-type":"print"},{"issue":"2","key":"23_36079840","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1038\/ajh.2009.228","volume":"23","author":"Thandapilly","year":"2010","journal-title":"American journal of hypertension : journal of the American Society of Hypertension","ISSN":"https:\/\/id.crossref.org\/issn\/0895-7061","issn-type":"print"},{"issue":"5","key":"24_36928339","doi-asserted-by":"publisher","first-page":"962","DOI":"10.3945\/jn.109.115006","volume":"140","year":"2010","journal-title":"The Journal of Nutrition","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3166","issn-type":"print"},{"issue":"7","key":"25_11096610","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1172\/JCI10947","volume":"107","author":"Chiu","year":"2001","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"issue":"8","key":"26_10804850","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1096\/fasebj.13.8.805","volume":"13","author":"BINAS","year":"1999","journal-title":"The FASEB Journal","ISSN":"https:\/\/id.crossref.org\/issn\/0892-6638","issn-type":"print"},{"issue":"5","key":"27_4906487","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1161\/01.HYP.11.5.416","volume":"11","author":"Taegtmeyer","year":"1988","journal-title":"Hypertension","ISSN":"https:\/\/id.crossref.org\/issn\/0194-911X","issn-type":"print"},{"issue":"4","key":"28_5694603","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1056\/NEJM199007263230405","volume":"323","author":"Levine","year":"1990","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"12","key":"29_19671160","doi-asserted-by":"publisher","first-page":"6668","DOI":"10.1073\/pnas.111155798","volume":"98","year":"2001","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"4","key":"30_16891022","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1161\/hc0402.102863","volume":"105","author":"Hirotani","year":"2002","journal-title":"Circulation","ISSN":"https:\/\/id.crossref.org\/issn\/0009-7322","issn-type":"print"},{"issue":"2","key":"31_16921731","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1006\/jmcc.2001.1505","volume":"34","author":"Higuchi","year":"2002","journal-title":"Journal of molecular and cellular cardiology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2828","issn-type":"print"},{"issue":"6","key":"32_17385044","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1083\/jcb.200207149","volume":"159","year":"2002","journal-title":"The Journal of Cell Biology","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9525","issn-type":"print"},{"issue":"4","key":"33_19645096","doi-asserted-by":"publisher","first-page":"H1712","DOI":"10.1152\/ajpheart.00124.2004","volume":"287","year":"2004","journal-title":"American Journal of Physiology - Heart and Circulatory Physiology","ISSN":"https:\/\/id.crossref.org\/issn\/0363-6135","issn-type":"print"},{"issue":"7","key":"34_28303087","doi-asserted-by":"publisher","first-page":"1913","DOI":"10.1038\/sj.emboj.7601633","volume":"26","author":"Gerhart-Hines","year":"2007","journal-title":"The EMBO Journal","ISSN":"https:\/\/id.crossref.org\/issn\/0261-4189","issn-type":"print"}],"container-title":["Cardiovascular Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cardiovascres\/article-pdf\/90\/2\/276\/789567\/cvq376.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,14]],"date-time":"2021-11-14T10:23:28Z","timestamp":1636885408000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cardiovascres\/article-lookup\/doi\/10.1093\/cvr\/cvq376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11,29]]},"references-count":34,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2011,4,18]]},"published-print":{"date-parts":[[2011,5,1]]}},"URL":"https:\/\/doi.org\/10.1093\/cvr\/cvq376","relation":{},"ISSN":["0008-6363"],"issn-type":[{"value":"0008-6363","type":"print"}],"subject":[],"published":{"date-parts":[[2010,11,29]]}}}