{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T19:46:47Z","timestamp":1792007207835,"version":"4.4.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,12,1]]},"DOI":"10.1093\/cvr\/cvt184","type":"journal-article","created":{"date-parts":[[2013,7,19]],"date-time":"2013-07-19T02:10:52Z","timestamp":1374199852000},"page":"354-362","source":"Crossref","is-referenced-by-count":68,"title":["Induction of pulmonary hypertensive changes by extracellular vesicles from monocrotaline-treated mice"],"prefix":"10.1093","volume":"100","author":[{"given":"Jason M.","family":"Aliotta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mandy","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Amaral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arina","family":"Sorokina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zenas","family":"Igbinoba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Hasslinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabih","family":"El-Bizri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon I.","family":"Rounds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Quesenberry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James R.","family":"Klinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,7,18]]},"reference":[{"key":"key\n\t\t\t\t20170519080014_CVT184C1","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1172\/JCI1910","article-title":"Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension","volume":"101","author":"Lee","year":"1998","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20170519080014_CVT184C2","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1097\/MED.0b013e32835057e9","article-title":"Microvesicles: potential markers and mediators of endothelial dysfunction","volume":"19","author":"Liu","year":"2012","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"key":"key\n\t\t\t\t20170519080014_CVT184C3","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1164\/rccm.200710-1458OC","article-title":"Circulating endothelial microparticle levels predict hemodynamic severity of pulmonary hypertension","volume":"177","author":"Amabile","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"key\n\t\t\t\t20170519080014_CVT184C4","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1164\/rccm.200706-840OC","article-title":"Procoagulant membrane microparticles correlate with the severity of pulmonary arterial hypertension","volume":"177","author":"Bakouboula","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"key\n\t\t\t\t20170519080014_CVT184C5","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.healun.2009.06.005","article-title":"Increased CD62e(+) endothelial microparticle levels predict poor outcome in pulmonary hypertension patients","volume":"28","author":"Amabile","year":"2009","journal-title":"J Heart Lung Transplant"},{"key":"key\n\t\t\t\t20170519080014_CVT184C6","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1164\/rccm.200909-1347OC","article-title":"Circulating microparticles from pulmonary hypertensive rats induce endothelial dysfunction","volume":"182","author":"Tual-Chalot","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"key\n\t\t\t\t20170519080014_CVT184C7","doi-asserted-by":"crossref","first-page":"3.22.1","DOI":"10.1002\/0471143030.cb0322s30","article-title":"Isolation and characterization of exosomes from cell culture supernatants and biological fluids","volume":"30","author":"Thery","year":"2006","journal-title":"Curr Protoc Cell Biol"},{"key":"key\n\t\t\t\t20170519080014_CVT184C8","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.ceb.2009.03.007","article-title":"Exosomes-vesicular carriers for intercellular communication","volume":"21","author":"Simons","year":"2009","journal-title":"Curr Opin Cell Biol"},{"key":"key\n\t\t\t\t20170519080014_CVT184C9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3402\/jev.v2i0.20389","article-title":"As we wait: coping with an imperfect nomenclature for extracellular vesicles","volume":"2","author":"Gould","year":"2013","journal-title":"J Extracell Vesicle"},{"key":"key\n\t\t\t\t20170519080014_CVT184C10","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1634\/stemcells.2007-0128","article-title":"Alteration of marrow cell gene expression, protein production, and engraftment into lung by lung-derived microvesicles: a novel mechanism for phenotype modulation","volume":"25","author":"Aliotta","year":"2007","journal-title":"Stem Cells"},{"key":"key\n\t\t\t\t20170519080014_CVT184C11","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1089\/152581600319577","article-title":"Hematopoiesis and angiogenesis: a link between two apparently independent processes","volume":"9","author":"Ribatti","year":"2000","journal-title":"J Hematother Stem Cell Res"},{"key":"key\n\t\t\t\t20170519080014_CVT184C12","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1182\/blood-2005-04-1509","article-title":"Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells","volume":"106","author":"Ingram","year":"2005","journal-title":"Blood"},{"key":"key\n\t\t\t\t20170519080014_CVT184C13","doi-asserted-by":"crossref","first-page":"615","DOI":"10.2353\/ajpath.2008.070705","article-title":"Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension","volume":"172","author":"Asosingh","year":"2008","journal-title":"Am J Pathol"},{"key":"key\n\t\t\t\t20170519080014_CVT184C14","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1055\/s-0028-1104547","article-title":"Microparticles in health and disease","volume":"34","author":"Enjeti","year":"2008","journal-title":"Semin Thromb Hemost"},{"key":"key\n\t\t\t\t20170519080014_CVT184C15","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1038\/sj.leu.2404296","article-title":"Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication","volume":"20","author":"Ratajczak","year":"2006","journal-title":"Leukemia"},{"key":"key\n\t\t\t\t20170519080014_CVT184C16","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.exphem.2010.01.002","article-title":"Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription","volume":"38","author":"Aliotta","year":"2010","journal-title":"Exp Hematol"},{"key":"key\n\t\t\t\t20170519080014_CVT184C17","doi-asserted-by":"crossref","first-page":"18163","DOI":"10.3402\/jev.v1i0.18163","article-title":"Persistence of microvesicle-induced bone marrow cell phenotypic changes in long term in vitro and in vivo transplantation models","volume":"1","author":"Aliotta","year":"2012","journal-title":"J Extracell Vesicle"},{"key":"key\n\t\t\t\t20170519080014_CVT184C18","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1183\/09031936.00112809","article-title":"Endothelial progenitors in pulmonary hypertension: new pathophysiology and therapeutic implications","volume":"35","author":"Fadini","year":"2010","journal-title":"Eur Respir J"},{"key":"key\n\t\t\t\t20170519080014_CVT184C19","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1183\/09031936.00130809","article-title":"Distinct patterns of circulating endothelial cells in pulmonary hypertension","volume":"36","author":"Smadja","year":"2010","journal-title":"Eur Respir J"},{"key":"key\n\t\t\t\t20170519080014_CVT184C20","doi-asserted-by":"crossref","first-page":"201","DOI":"10.4103\/2045-8932.97606","article-title":"Metabolomic analysis of bone morphogenetic protein receptor type 2 mutations in human pulmonary endothelium reveals widespread metabolic reprogramming","volume":"2","author":"Fessel","year":"2012","journal-title":"Pulm Circ"},{"key":"key\n\t\t\t\t20170519080014_CVT184C21","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1164\/rccm.201108-1536PP","article-title":"Targeting energetic metabolism: a new frontier in the pathogenesis and treatment of pulmonary hypertension","volume":"185","author":"Tuder","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"key\n\t\t\t\t20170519080014_CVT184C22","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1164\/rccm.200909-1347OC","article-title":"Circulating microparticles from pulmonary hypertensive rats induce endothelial dysfunction","volume":"182","author":"Tual-Chalot","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"key\n\t\t\t\t20170519080014_CVT184C23","doi-asserted-by":"crossref","first-page":"L196","DOI":"10.1152\/ajplung.00433.2004","article-title":"Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells","volume":"289","author":"Zhu","year":"2005","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"key\n\t\t\t\t20170519080014_CVT184C24","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1161\/ATVBAHA.109.202028","article-title":"Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline","volume":"30","author":"Caruso","year":"2010","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"key\n\t\t\t\t20170519080014_CVT184C25","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1158\/0008-5472.CAN-12-0271","article-title":"MicroRNAs regulate tumor angiogenesis modulated by endothelial progenitor cells","volume":"73","author":"Plummer","year":"2013","journal-title":"Cancer Res"}],"container-title":["Cardiovascular Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cardiovascres\/article-pdf\/100\/3\/354\/17235251\/cvt184.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,18]],"date-time":"2019-07-18T21:36:55Z","timestamp":1563485815000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cardiovascres\/article-lookup\/doi\/10.1093\/cvr\/cvt184"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,18]]},"references-count":25,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2013,7,18]]},"published-print":{"date-parts":[[2013,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/cvr\/cvt184","relation":{},"ISSN":["1755-3245","0008-6363"],"issn-type":[{"value":"1755-3245","type":"electronic"},{"value":"0008-6363","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7,18]]}}}