{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:34:33Z","timestamp":1790739273020,"version":"4.1.0"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,9,1]]},"DOI":"10.1093\/cvr\/cvu161","type":"journal-article","created":{"date-parts":[[2014,6,21]],"date-time":"2014-06-21T05:43:40Z","timestamp":1403329420000},"page":"509-520","source":"Crossref","is-referenced-by-count":33,"title":["Expression of fibulin-6 in failing hearts and its role for cardiac fibroblast migration"],"prefix":"10.1093","volume":"103","author":[{"given":"Arpita","family":"Chowdhury","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Herzog","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Hasselbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houra","family":"Loghmani Khouzani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinli","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Hammerschmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten","family":"Rudat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Kispert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Gaestel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoj B.","family":"Menon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Tudorache","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Hilfiker-Kleiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"M\u00fchlfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan Dieter","family":"Schmitto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor","family":"Theilmeier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,6,20]]},"reference":[{"key":"key\n\t\t\t\t20170518150010_CVU161C1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1097\/00004872-200401000-00011","article-title":"Fibrosis in hypertensive heart disease: focus on cardiac fibroblasts","volume":"22","author":"Weber","year":"2004","journal-title":"J Hypertens"},{"key":"key\n\t\t\t\t20170518150010_CVU161C2","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.yjmcc.2009.08.024","article-title":"The extracellular matrix: at the center of it all","volume":"48","author":"Bowers","year":"2010","journal-title":"J Mol Cell Cardiol"},{"key":"key\n\t\t\t\t20170518150010_CVU161C3","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1242\/jcs.006064","article-title":"Extracellular matrix dynamics in development and regenerative medicine","volume":"121","author":"Daley","year":"2008","journal-title":"J Cell Sci"},{"key":"key\n\t\t\t\t20170518150010_CVU161C4","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1007\/s00018-009-8632-6","article-title":"Fibulins: multiple roles in matrix structures and tissue functions","volume":"66","author":"de Vega","year":"2009","journal-title":"Cell Mol Life Sci"},{"key":"key\n\t\t\t\t20170518150010_CVU161C5","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1242\/dev.128.6.883","article-title":"Hemicentin, a conserved extracellular member of the immunoglobulin superfamily, organizes epithelial and other cell attachments into oriented line-shaped junctions","volume":"128","author":"Vogel","year":"2001","journal-title":"Development"},{"key":"key\n\t\t\t\t20170518150010_CVU161C6","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1038\/sj.cr.7310100","article-title":"Hemicentins: what have we learned from worms?","volume":"16","author":"Vogel","year":"2006","journal-title":"Cell Res"},{"key":"key\n\t\t\t\t20170518150010_CVU161C7","doi-asserted-by":"crossref","first-page":"e1000907","DOI":"10.1371\/journal.pgen.1000907","article-title":"Genetic analysis of fin development in zebrafish identifies furin and hemicentin1 as potential novel fraser syndrome disease genes","volume":"6","author":"Carney","year":"2010","journal-title":"PLoS Genet"},{"key":"key\n\t\t\t\t20170518150010_CVU161C8","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1369\/jhc.6A6975.2006","article-title":"Hemicentins assemble on diverse epithelia in the mouse","volume":"55","author":"Xu","year":"2007","journal-title":"J Histochem Cytochem"},{"key":"key\n\t\t\t\t20170518150010_CVU161C9","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.cub.2010.12.006","article-title":"A secreted protein promotes cleavage furrow maturation during cytokinesis","volume":"21","author":"Xu","year":"2011","journal-title":"Curr Biol"},{"key":"key\n\t\t\t\t20170518150010_CVU161C10","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/2045-3701-3-27","article-title":"Specific structure and unique function define the hemicentin","volume":"3","author":"Xu","year":"2013","journal-title":"Cell Biosci"},{"key":"key\n\t\t\t\t20170518150010_CVU161C11","doi-asserted-by":"crossref","first-page":"R119","DOI":"10.1016\/j.cub.2010.12.040","article-title":"Cytokinesis: thinking outside the cell","volume":"21","author":"Jordan","year":"2011","journal-title":"Curr Biol"},{"key":"key\n\t\t\t\t20170518150010_CVU161C12","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1475-2840-12-6","article-title":"Plasma concentrations of extracellular matrix protein fibulin-1 are related to cardiovascular risk markers in chronic kidney disease and diabetes","volume":"12","author":"Scholze","year":"2013","journal-title":"Cardiovasc Diabetol"},{"key":"key\n\t\t\t\t20170518150010_CVU161C13","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.yjmcc.2011.11.001","article-title":"Loss of fibulin-2 protects against progressive ventricular dysfunction after myocardial infarction","volume":"52","author":"Tsuda","year":"2012","journal-title":"J Mol Cell Cardiol"},{"key":"key\n\t\t\t\t20170518150010_CVU161C14","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1161\/01.RES.0000260181.19449.95","article-title":"Perturbations of vascular homeostasis and aortic valve abnormalities in fibulin-4 deficient mice","volume":"100","author":"Hanada","year":"2007","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20170518150010_CVU161C15","doi-asserted-by":"crossref","first-page":"2946","DOI":"10.1073\/pnas.0500058102","article-title":"Altered vascular remodeling in fibulin-5-deficient mice reveals a role of fibulin-5 in smooth muscle cell proliferation and migration","volume":"102","author":"Spencer","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170518150010_CVU161C16","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.gene.2010.05.003","article-title":"Molecular evolution of the fibulins: implications on the functionality of the elastic fibulins","volume":"464","author":"Segade","year":"2010","journal-title":"Gene"},{"key":"key\n\t\t\t\t20170518150010_CVU161C17","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1007\/s000180050188","article-title":"Ultrastructural localization of microfibrillar fibulin-1 and fibulin-2 during heart development indicates a switch in molecular associations","volume":"54","author":"Miosge","year":"1998","journal-title":"Cell Mol Life Sci"},{"key":"key\n\t\t\t\t20170518150010_CVU161C18","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1161\/01.RES.86.9.939","article-title":"Altered patterns of gene expression in response to myocardial infarction","volume":"86","author":"Stanton","year":"2000","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20170518150010_CVU161C19","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1161\/CIRCULATIONAHA.111.056952","article-title":"Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia\/reperfusion injury","volume":"125","author":"Barallobre-Barreiro","year":"2012","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20170518150010_CVU161C20","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1083\/jcb.17.2.299","article-title":"Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines","volume":"17","author":"Todaro","year":"1963","journal-title":"J Cell Biol"},{"key":"key\n\t\t\t\t20170518150010_CVU161C21","doi-asserted-by":"crossref","first-page":"107","DOI":"10.22203\/eCM.v021a09","article-title":"Cardiogel supports adhesion, proliferation and differentiation of stem cells with increased oxidative stress protection","volume":"21","author":"Sreejit","year":"2011","journal-title":"Eur Cell Mater"},{"key":"key\n\t\t\t\t20170518150010_CVU161C22","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1002\/cm.20418","article-title":"Fluorescence-based quantitative scratch wound healing assay demonstrating the role of mapkapk-2\/3 in fibroblast migration","volume":"66","author":"Menon","year":"2009","journal-title":"Cell Motil Cytoskeleton"},{"key":"key\n\t\t\t\t20170518150010_CVU161C23","doi-asserted-by":"crossref","first-page":"10647","DOI":"10.1074\/jbc.M611339200","article-title":"Cleavage and oligomerization of gliomedin, a transmembrane collagen required for node of ranvier formation","volume":"282","author":"Maertens","year":"2007","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170518150010_CVU161C24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/002215540104900101","article-title":"Sensitive nonradioactive detection of mRNA in tissue sections: novel application of the whole-mount in situ hybridization protocol","volume":"49","author":"Moorman","year":"2001","journal-title":"J Histochem Cytochem"},{"key":"key\n\t\t\t\t20170518150010_CVU161C25","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1091\/mbc.E09-07-0567","article-title":"The RhoA activator GEF-H1\/Lfc is a transforming growth factor-beta target gene and effector that regulates alpha-smooth muscle actin expression and cell migration","volume":"21","author":"Tsapara","year":"2010","journal-title":"Mol Biol Cell"},{"key":"key\n\t\t\t\t20170518150010_CVU161C26","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1161\/HYPERTENSIONAHA.106.080242","article-title":"Angiotensin II induces angiogenesis in the hypoxic adult mouse heart in vitro through an AT2-B2 receptor pathway","volume":"49","author":"Munk","year":"2007","journal-title":"Hypertension"},{"key":"key\n\t\t\t\t20170518150010_CVU161C27","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1755-1536-5-15","article-title":"Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease","volume":"5","author":"Fan","year":"2012","journal-title":"Fibrogenesis Tissue Repair"},{"key":"key\n\t\t\t\t20170518150010_CVU161C28","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1146\/annurev.pharmtox.45.120403.095802","article-title":"The cardiac fibroblast: therapeutic target in myocardial remodeling and failure","volume":"45","author":"Brown","year":"2005","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"key\n\t\t\t\t20170518150010_CVU161C29","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.cardiores.2004.08.020","article-title":"Structural and functional characterisation of cardiac fibroblasts","volume":"65","author":"Camelliti","year":"2005","journal-title":"Cardiovasc Res"},{"key":"key\n\t\t\t\t20170518150010_CVU161C30","doi-asserted-by":"crossref","first-page":"H1015","DOI":"10.1152\/ajpheart.00023.2006","article-title":"Cardiac fibroblasts: friend or foe?","volume":"291","author":"Baudino","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"Suppl 2","key":"key\n\t\t\t\t20170518150010_CVU161C31","first-page":"183","article-title":"Cardiac fibroblasts: function, regulation of gene expression, and phenotypic modulation","volume":"87","author":"Eghbali","year":"1992","journal-title":"Basic Res Cardiol"},{"key":"key\n\t\t\t\t20170518150010_CVU161C32","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1165\/ajrcmb\/8.5.538","article-title":"Fibulin's organization into the extracellular matrix of fetal lung fibroblasts is dependent on fibronectin matrix assembly","volume":"8","author":"Roman","year":"1993","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"Pt 12","key":"key\n\t\t\t\t20170518150010_CVU161C33","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1242\/jcs.109.12.2895","article-title":"Expression of fibulin-2 by fibroblasts and deposition with fibronectin into a fibrillar matrix","volume":"109","author":"Sasaki","year":"1996","journal-title":"J Cell Sci"},{"key":"key\n\t\t\t\t20170518150010_CVU161C34","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1080\/02713680701411269","article-title":"Expression of extracellular matrix proteins fibulin-1 and fibulin-2 by human corneal fibroblasts","volume":"32","author":"Ducros","year":"2007","journal-title":"Curr Eye Res"},{"key":"key\n\t\t\t\t20170518150010_CVU161C35","doi-asserted-by":"crossref","first-page":"L1147","DOI":"10.1152\/ajplung.00098.2003","article-title":"Coordinate expression of fibulin-5\/DANCE and elastin during lung injury repair","volume":"285","author":"Kuang","year":"2003","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"key\n\t\t\t\t20170518150010_CVU161C36","doi-asserted-by":"crossref","first-page":"3315","DOI":"10.1093\/hmg\/ddg348","article-title":"Analysis of the ARMD1 locus: evidence that a mutation in hemicentin-1 is associated with age-related macular degeneration in a large family","volume":"12","author":"Schultz","year":"2003","journal-title":"Hum Mol Genet"},{"key":"key\n\t\t\t\t20170518150010_CVU161C37","first-page":"89","article-title":"TGF-beta receptor expression and SMAD2 localization are cell density dependent in fibroblasts","volume":"41","author":"Petridou","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"key\n\t\t\t\t20170518150010_CVU161C38","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1161\/CIRCRESAHA.109.209809","article-title":"Cardiac fibroblast: the renaissance cell","volume":"105","author":"Souders","year":"2009","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20170518150010_CVU161C39","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1038\/nature07511","article-title":"Microrna-21 contributes to myocardial disease by stimulating map kinase signalling in fibroblasts","volume":"456","author":"Thum","year":"2008","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170518150010_CVU161C40","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0945-053X(00)00077-9","article-title":"Fibroblast-matrix interactions in wound healing and fibrosis","volume":"19","author":"Eckes","year":"2000","journal-title":"Matrix Biol"},{"key":"key\n\t\t\t\t20170518150010_CVU161C41","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1524-475X.2011.00673.x","article-title":"Dynamic reciprocity in the wound microenvironment","volume":"19","author":"Schultz","year":"2011","journal-title":"Wound Repair Regen"},{"key":"key\n\t\t\t\t20170518150010_CVU161C42","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1242\/jcs.031187","article-title":"Wound repair at a glance","volume":"122","author":"Shaw","year":"2009","journal-title":"J Cell Sci"},{"key":"key\n\t\t\t\t20170518150010_CVU161C43","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1042\/BJ20110348","article-title":"Fibulin-5 binds urokinase-type plasminogen activator and mediates urokinase-stimulated beta1-integrin-dependent cell migration","volume":"443","author":"Kapustin","year":"2012","journal-title":"Biochem J"},{"key":"key\n\t\t\t\t20170518150010_CVU161C44","doi-asserted-by":"crossref","first-page":"540","DOI":"10.3109\/02713683.2012.665561","article-title":"Overexpression of fibulin-5 in retinal pigment epithelial cells inhibits cell proliferation and migration and downregulates VEGF, CXCR4, and TGFB1 expression in cocultured choroidal endothelial cells","volume":"37","author":"Li","year":"2012","journal-title":"Curr Eye Res"},{"key":"key\n\t\t\t\t20170518150010_CVU161C45","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.cardiores.2005.12.001","article-title":"Fibulin-2 is present in murine vascular lesions and is important for smooth muscle cell migration","volume":"69","author":"Strom","year":"2006","journal-title":"Cardiovasc Res"},{"key":"key\n\t\t\t\t20170518150010_CVU161C46","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.ydbio.2012.06.023","article-title":"Hemicentin 2 and fibulin 1 are required for epidermal-dermal junction formation and fin mesenchymal cell migration during zebrafish development","volume":"369","author":"Feitosa","year":"2012","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170518150010_CVU161C47","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1038\/nm1613","article-title":"Endothelial-to-mesenchymal transition contributes to cardiac fibrosis","volume":"13","author":"Zeisberg","year":"2007","journal-title":"Nat Med"},{"key":"key\n\t\t\t\t20170518150010_CVU161C48","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.pharmthera.2009.05.002","article-title":"Cardiac fibroblasts: at the heart of myocardial remodeling","volume":"123","author":"Porter","year":"2009","journal-title":"Pharmacol Ther"},{"key":"key\n\t\t\t\t20170518150010_CVU161C49","first-page":"1122","article-title":"Alpha-smooth muscle actin expression in cultured lens epithelial cells","volume":"41","author":"Nagamoto","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"key\n\t\t\t\t20170518150010_CVU161C50","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.3748\/wjg.15.1431","article-title":"Transforming growth factor-beta 1 induces intestinal myofibroblast differentiation and modulates their migration","volume":"15","author":"Brenmoehl","year":"2009","journal-title":"World J Gastroenterol"}],"container-title":["Cardiovascular Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cardiovascres\/article-pdf\/103\/4\/509\/17194475\/cvu161.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,9]],"date-time":"2022-04-09T01:41:58Z","timestamp":1649468518000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cardiovascres\/article-lookup\/doi\/10.1093\/cvr\/cvu161"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,20]]},"references-count":50,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2014,6,20]]},"published-print":{"date-parts":[[2014,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/cvr\/cvu161","relation":{},"ISSN":["1755-3245","0008-6363"],"issn-type":[{"value":"1755-3245","type":"electronic"},{"value":"0008-6363","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6,20]]}}}