{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T04:08:34Z","timestamp":1777090114131,"version":"3.51.4"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"3","funder":[{"DOI":"10.13039\/501100003246","name":"Netherlands Organisation for Scientific Research","doi-asserted-by":"crossref","award":["91714336"],"award-info":[{"award-number":["91714336"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Ammodo"},{"name":"Japanese Society of Electrocardiology","award":["2013"],"award-info":[{"award-number":["2013"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,3,1]]},"DOI":"10.1093\/cvr\/cvx003","type":"journal-article","created":{"date-parts":[[2017,1,30]],"date-time":"2017-01-30T13:24:41Z","timestamp":1485782681000},"page":"354-366","source":"Crossref","is-referenced-by-count":31,"title":["Optogenetic manipulation of anatomical re-entry by light-guided generation of a reversible local conduction block"],"prefix":"10.1093","volume":"113","author":[{"given":"Masaya","family":"Watanabe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iolanda","family":"Feola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rupamanjari","family":"Majumder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanchana","family":"Jangsangthong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander S.","family":"Teplenin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk L.","family":"Ypey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin J.","family":"Schalij","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katja","family":"Zeppenfeld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoine A. F.","family":"de Vries","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dani\u00ebl A.","family":"Pijnappels","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2017,1,10]]},"reference":[{"key":"key\n\t\t\t\t20180328162300_cvx003-B1","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1023\/A:1021109130276","article-title":"Electrophysiology studies in patients with dilated cardiomyopathies","volume":"6","author":"Hsia","year":"2002","journal-title":"Card Electrophysiol Rev"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B2","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1161\/01.CIR.57.3.431","article-title":"Recurrent sustained ventricular tachycardia. 1. Mechanisms","volume":"57","author":"Josephson","year":"1978","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B3","first-page":"III41","article-title":"Mechanisms of ventricular tachycardia","volume":"75","author":"Josephson","year":"1987","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B4","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1001\/jama.295.2.165","article-title":"Optimal pharmacological therapy in cardioverter defibrillator patients I. Comparison of beta-blockers, amiodarone plus beta-blockers, or sotalol for prevention of shocks from implantable cardioverter defibrillators: the OPTIC Study: a randomized trial","volume":"295","author":"Connolly","year":"2006","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B5","doi-asserted-by":"crossref","first-page":"3760","DOI":"10.1161\/01.CIR.0000150390.04704.B7","article-title":"Long-term clinical course of patients after termination of ventricular tachyarrhythmia by an implanted defibrillator","volume":"110","author":"Moss","year":"2004","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B6","doi-asserted-by":"crossref","first-page":"2750","DOI":"10.1161\/CIRCULATIONAHA.106.655720","article-title":"Catheter ablation for ventricular tachycardia","volume":"115","author":"Stevenson","year":"2007","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B7","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.pbiomolbio.2014.07.001","article-title":"Cardiac applications of optogenetics","volume":"115","author":"Ambrosi","year":"2014","journal-title":"Prog Biophys Mol Biol"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B8","doi-asserted-by":"crossref","first-page":"H1179","DOI":"10.1152\/ajpheart.00432.2012","article-title":"Cardiac optogenetics","volume":"304","author":"Entcheva","year":"2013","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B9","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1038\/nmeth.1512","article-title":"Optogenetic control of heart muscle in vitro and in vivo","volume":"7","author":"Bruegmann","year":"2010","journal-title":"Nat Methods"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B10","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1093\/cvr\/cvu037","article-title":"Modulation of cardiac tissue electrophysiological properties with light-sensitive proteins","volume":"102","author":"Nussinovitch","year":"2014","journal-title":"Cardiovasc Res"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B11","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1038\/nbt.3268","article-title":"Optogenetics for in vivo cardiac pacing and resynchronization therapies","volume":"33","author":"Nussinovitch","year":"2015","journal-title":"Nat Biotechnol"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B12","doi-asserted-by":"crossref","first-page":"031204","DOI":"10.1117\/1.NPh.2.3.031204","article-title":"Optogenetics for suppression of cardiac electrical activity in human and rat cardiomyocyte cultures","volume":"2","author":"Nussinovitch","year":"2015","journal-title":"Neurophotonics"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B13","doi-asserted-by":"crossref","first-page":"6125","DOI":"10.1038\/srep06125","article-title":"Optical mapping of optogenetically shaped cardiac action potentials","volume":"4","author":"Park","year":"2014","journal-title":"Sci Rep"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B14","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.jneumeth.2014.12.002","article-title":"Optical dissection of brain circuits with patterned illumination through the phase modulation of light","volume":"241","author":"Bovetti","year":"2015","journal-title":"J Neurosci Methods"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B15","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1038\/nn.3427","article-title":"Targeting neurons and photons for optogenetics","volume":"16","author":"Packer","year":"2013","journal-title":"Nat Neurosci"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B16","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/boc.201200087","article-title":"Optical developments for optogenetics","volume":"105","author":"Papagiakoumou","year":"2013","journal-title":"Biol Cell"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B17","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1038\/ncomms2500","article-title":"Holographic optogenetic stimulation of patterned neuronal activity for vision restoration","volume":"4","author":"Reutsky-Gefen","year":"2013","journal-title":"Nat Commun"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B18","doi-asserted-by":"crossref","first-page":"3894","DOI":"10.1172\/JCI88950","article-title":"Optogenetic defibrillation terminates ventricular arrhythmia in mouse hearts and human simulations","volume":"126","author":"Bruegmann","year":"2016","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B19","doi-asserted-by":"crossref","first-page":"35628","DOI":"10.1038\/srep35628","article-title":"Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation","volume":"6","author":"Crocini","year":"2016","journal-title":"Sci Rep"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B20","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/nn.2776","article-title":"Ultra light-sensitive and fast neuronal activation with the Ca(2)+-permeable channelrhodopsin CatCh","volume":"14","author":"Kleinlogel","year":"2011","journal-title":"Nat Neurosci"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B21","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/j.bpj.2008.10.026","article-title":"Model of excitation-contraction coupling of rat neonatal ventricular myocytes","volume":"96","author":"Korhonen","year":"2009","journal-title":"Biophys J"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B22","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1161\/CIRCRESAHA.110.232470","article-title":"A major role for HERG in determining frequency of reentry in neonatal rat ventricular myocyte monolayer","volume":"107","author":"Hou","year":"2010","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B23","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1113\/expphysiol.2008.044065","article-title":"Organization of ventricular fibrillation in the human heart: experiments and models","volume":"94","author":"ten Tusscher","year":"2009","journal-title":"Exp Physiol"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B24","doi-asserted-by":"crossref","first-page":"4121","DOI":"10.1529\/biophysj.106.101410","article-title":"A mathematical model of electrotonic interactions between ventricular myocytes and fibroblasts","volume":"92","author":"MacCannell","year":"2007","journal-title":"Biophys J"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B25","doi-asserted-by":"crossref","first-page":"e1003220","DOI":"10.1371\/journal.pcbi.1003220","article-title":"Computational optogenetics: empirically-derived voltage- and light-sensitive channelrhodopsin-2 model","volume":"9","author":"Williams","year":"2013","journal-title":"PLoS Comput Biol"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B26","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1038\/ncomms3370","article-title":"A comprehensive multiscale framework for simulating optogenetics in the heart","volume":"4","author":"Boyle","year":"2013","journal-title":"Nat Commun"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B27","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1093\/cvr\/cvu179","article-title":"Light-induced termination of spiral wave arrhythmias by optogenetic engineering of atrial cardiomyocytes","volume":"104","author":"Bingen","year":"2014","journal-title":"Cardiovasc Res"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B28","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1152\/physrev.00025.2003","article-title":"Basic mechanisms of cardiac impulse propagation and associated arrhythmias","volume":"84","author":"Kleber","year":"2004","journal-title":"Physiol Rev"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B29","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1126\/science.275.5301.841","article-title":"Paradoxical improvement of impulse conduction in cardiac tissue by partial cellular uncoupling","volume":"275","author":"Rohr","year":"1997","journal-title":"Science"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B30","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1126\/science.1195929","article-title":"Optogenetic control of cardiac function","volume":"330","author":"Arrenberg","year":"2010","journal-title":"Science"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B31","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1161\/01.RES.75.6.1014","article-title":"Wave-front curvature as a cause of slow conduction and block in isolated cardiac muscle","volume":"75","author":"Cabo","year":"1994","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B32","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0008-6363(95)00071-2","article-title":"Block of impulse propagation at an abrupt tissue expansion: evaluation of the critical strand diameter in 2- and 3-dimensional computer models","volume":"30","author":"Fast","year":"1995","journal-title":"Cardiovasc Res"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B33","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0008-6363(03)00360-2","article-title":"Developmental changes in IKr and IKs contribute to age-related expression of dofetilide effects on repolarization and proarrhythmia","volume":"59","author":"Obreztchikova","year":"2003","journal-title":"Cardiovasc Res."},{"key":"key\n\t\t\t\t20180328162300_cvx003-B34","first-page":"127","article-title":"Are M cells present in the ventricular myocardium of the pig? A question of maturity","volume":"36","author":"Antzelevitch","year":"1997","journal-title":"Cardiovasc Res"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B35","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.yjmcc.2013.09.001","article-title":"Developmental changes in expression and biophysics of ion channels in the canine ventricle","volume":"64","author":"Cordeiro","year":"2013","journal-title":"J Mol Cell Cardiol."},{"key":"key\n\t\t\t\t20180328162300_cvx003-B36","doi-asserted-by":"crossref","first-page":"4","DOI":"10.4172\/2157-7013.1000126","article-title":"Histological validation of heart slices as a model in cardiac research","volume":"3","author":"Kaneko","year":"2012","journal-title":"J Cell Sci Ther"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B37","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1161\/01.RES.68.6.1638","article-title":"Spatial distribution of connexin43, the major cardiac gap junction protein, in the developing and adult rat heart","volume":"68","author":"van Kempen","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B38","first-page":"4","article-title":"An in vitro method for adhesion of fresh adult murine heart slices on Collagen-coated surfaces","volume":"20","author":"Popa","year":"2015","journal-title":"Ann Roman Soc Cell Biol"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B39","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1093\/cvr\/cvv004","article-title":"Systemic gene transfer enables optogenetic pacing of mouse hearts","volume":"106","author":"Vogt","year":"2015","journal-title":"Cardiovasc Res"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B40","doi-asserted-by":"crossref","first-page":"E4495","DOI":"10.1073\/pnas.1509380112","article-title":"Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific targeting of ChannelRhodopsin-2","volume":"112","author":"Zaglia","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B41","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1038\/nn.3502","article-title":"ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation","volume":"16","author":"Lin","year":"2013","journal-title":"Nat Neurosci."},{"key":"key\n\t\t\t\t20180328162300_cvx003-B42","doi-asserted-by":"crossref","first-page":"31804","DOI":"10.1074\/jbc.M112.391185","article-title":"Color-tuned channelrhodopsins for multiwavelength optogenetics","volume":"287","author":"Prigge","year":"2012","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B43","doi-asserted-by":"crossref","first-page":"3329","DOI":"10.1038\/ncomms4329","article-title":"3D multifunctional integumentary membranes for spatiotemporal cardiac measurements and stimulation across the entire epicardium","volume":"5","author":"Xu","year":"2014","journal-title":"Nat Commun"},{"key":"key\n\t\t\t\t20180328162300_cvx003-B44","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1126\/science.1232437","article-title":"Injectable, cellular-scale optoelectronics with applications for wireless optogenetics","volume":"340","author":"Kim","year":"2013","journal-title":"Science"}],"container-title":["Cardiovascular Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cardiovascres\/article-pdf\/113\/3\/354\/10815098\/cvx003.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,14]],"date-time":"2025-06-14T21:38:53Z","timestamp":1749937133000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cardiovascres\/article\/113\/3\/354\/3003403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,10]]},"references-count":44,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2017,1,10]]},"published-print":{"date-parts":[[2017,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/cvr\/cvx003","relation":{},"ISSN":["0008-6363","1755-3245"],"issn-type":[{"value":"0008-6363","type":"print"},{"value":"1755-3245","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,3]]},"published":{"date-parts":[[2017,1,10]]}}}