{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:31:40Z","timestamp":1792042300987,"version":"4.4.0"},"reference-count":134,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T00:00:00Z","timestamp":1545350400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","award":["PG\/16\/85\/32471"],"award-info":[{"award-number":["PG\/16\/85\/32471"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","award":["PG\/18\/44\/33790"],"award-info":[{"award-number":["PG\/18\/44\/33790"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Institute for Health Research University College London Hospitals Biomedical Research Centre"},{"DOI":"10.13039\/100000050","name":"National Heart, Lung and Blood Institute","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"name":"United States of America","award":["R56 HL136816"],"award-info":[{"award-number":["R56 HL136816"]}]},{"name":"Russian Government Programme"},{"DOI":"10.13039\/501100012528","name":"Kazan Federal University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100012528","id-type":"DOI","asserted-by":"crossref"}]},{"name":"SHF-Foundation","award":["SHF\/FG657P\/2017"],"award-info":[{"award-number":["SHF\/FG657P\/2017"]}]},{"name":"von Behring-R\u00f6ntgen-Foundation"},{"DOI":"10.13039\/501100006692","name":"University of Turin","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006692","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Horizon 2020 Taxinomisis","award":["755320-2"],"award-info":[{"award-number":["755320-2"]}]},{"name":"Netherlands Cardiovascular Researeach Initiative"},{"name":"COST Action EU-CARDIOPROTECTION","award":["CA16225"],"award-info":[{"award-number":["CA16225"]}]},{"DOI":"10.13039\/501100000921","name":"European Cooperation in Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000921","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,6,1]]},"DOI":"10.1093\/cvr\/cvy304","type":"journal-article","created":{"date-parts":[[2018,12,15]],"date-time":"2018-12-15T07:08:53Z","timestamp":1544857733000},"page":"1131-1142","source":"Crossref","is-referenced-by-count":137,"title":["Innate immunity as a target for acute cardioprotection"],"prefix":"10.1093","volume":"115","author":[{"given":"Coert J","family":"Zuurbier","sequence":"first","affiliation":[{"name":"Laboratory of Experimental Intensive Care and Anesthesiology, Department of Anesthesiology, Amsterdam UMC, University of Amsterdam, Amsterdam Cardiovascular Sciences, 1081 HV Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Abbate","sequence":"additional","affiliation":[{"name":"VCU Pauley Heart Center and Wright Center for Clinical and Translational Research, Richmond, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hector A","family":"Cabrera-Fuentes","sequence":"additional","affiliation":[{"name":"Cardiovascular and Metabolic Disorders Program, Duke-NUS Medical School, Singapore, Singapore"},{"name":"National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore"},{"name":"Escuela de Ingenier\u00eda y Ciencias, Tecnologico de Monterrey, Centro de Biotecnolog\u00eda-FEMSA, Monterrey, Nuevo Le\u00f3n, M\u00e9xico"},{"name":"Department of Microbiology, Kazan Federal University, Kazan, Russian Federation"},{"name":"Institute of Biochemistry, Medical School, Justus-Liebig-University, Giessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael V","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of South Alabama College of Medicine, Mobile, AL, USA"},{"name":"Department of Physiology and Cell Biology, University of South Alabama College of Medicine, Mobile, AL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Collino","sequence":"additional","affiliation":[{"name":"Department of Drug Science and Technology, University of Turin, Torino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique P V","family":"De Kleijn","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, UMC Utrecht, Utrecht University, Utrecht, the Netherlands"},{"name":"Netherlands Heart Institute, Utrecht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James M","family":"Downey","sequence":"additional","affiliation":[{"name":"Department of Physiology and Cell Biology, University of South Alabama College of Medicine, Mobile, AL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasquale","family":"Pagliaro","sequence":"additional","affiliation":[{"name":"Department of Biological and Clinical Sciences, University of Turin, Torino, Italy"},{"name":"National Institute for Cardiovascular Research, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus T","family":"Preissner","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Medical School, Justus-Liebig-University, Giessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masafumi","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean M","family":"Davidson","sequence":"additional","affiliation":[{"name":"The Hatter Cardiovascular Institute, University College London, 67 Chenies Mews, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,12,21]]},"reference":[{"key":"2019052205002549600_cvy304-B1","first-page":"935","article-title":"Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations","volume":"38","author":"Hausenloy","year":"2017","journal-title":"Eur Heart J"},{"key":"2019052205002549600_cvy304-B2","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1016\/j.jacc.2016.01.069","article-title":"Relationship between infarct size and outcomes following primary PCI: patient-level analysis from 10 randomized trials","volume":"67","author":"Stone","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"2019052205002549600_cvy304-B3","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1093\/cvr\/cvx049","article-title":"Novel targets and future strategies for acute cardioprotection: position paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart","volume":"113","author":"Hausenloy","year":"2017","journal-title":"Cardiovasc Res"},{"key":"2019052205002549600_cvy304-B4","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1007\/s00395-016-0588-8","article-title":"Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery","volume":"111","author":"Hausenloy","year":"2016","journal-title":"Basic Res Cardiol"},{"key":"2019052205002549600_cvy304-B5","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s00395-016-0558-1","article-title":"9th Hatter Biannual Meeting: position document on ischaemia\/reperfusion injury, conditioning and the ten commandments of cardioprotection","volume":"111","author":"Bell","year":"2016","journal-title":"Basic Res Cardiol"},{"key":"2019052205002549600_cvy304-B6","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s00395-018-0704-z","article-title":"The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection-evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology","volume":"113","author":"Davidson","year":"2018","journal-title":"Basic Res Cardiol"},{"key":"2019052205002549600_cvy304-B7","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1093\/cvr\/cvz050","article-title":"Immune cells as targets for cardioprotection: new players and novel therapeutic opportunities","volume":"115","author":"Andreadou","year":"2019","journal-title":"Cardiovasc Res"},{"key":"2019052205002549600_cvy304-B8","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/nrcardio.2017.161","article-title":"The NLRP3 inflammasome in acute myocardial infarction","volume":"15","author":"Toldo","year":"2018","journal-title":"Nat Rev Cardiol"},{"key":"2019052205002549600_cvy304-B9","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1038\/nrcardio.2011.38","article-title":"Innate immune signaling in cardiac ischemia","volume":"8","author":"Arslan","year":"2011","journal-title":"Nat Rev Cardiol"},{"key":"2019052205002549600_cvy304-B10","doi-asserted-by":"crossref","first-page":"496","DOI":"10.3389\/fphys.2014.00496","article-title":"Ischemia\/reperfusion activates myocardial innate immune response: the key role of the toll-like receptor","volume":"5","author":"Vilahur","year":"2014","journal-title":"Front Physiol"},{"key":"2019052205002549600_cvy304-B11","first-page":"653","article-title":"Innate immune inflammatory response in the acutely ischemic myocardium","volume":"10","author":"Deftereos","year":"2014","journal-title":"Med Clin"},{"key":"2019052205002549600_cvy304-B12","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/nature00858","article-title":"Release of chromatin protein HMGB1 by necrotic cells triggers inflammation","volume":"418","author":"Scaffidi","year":"2002","journal-title":"Nature"},{"key":"2019052205002549600_cvy304-B13","doi-asserted-by":"crossref","first-page":"828354","DOI":"10.1155\/2013\/828354","article-title":"S100A8 and S100A9: DAMPs at the crossroads between innate immunity, traditional risk factors, and cardiovascular disease","volume":"2013","author":"Schiopu","year":"2013","journal-title":"Mediators Inflamm"},{"key":"2019052205002549600_cvy304-B14","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1160\/TH-16-11-0858","article-title":"Extracellular nucleic acids in immunity and cardiovascular responses: between alert and disease","volume":"117","author":"Preissner","year":"2017","journal-title":"Thromb Haemost"},{"key":"2019052205002549600_cvy304-B15","doi-asserted-by":"crossref","first-page":"851","DOI":"10.2119\/molmed.2012.00011","article-title":"Mammalian DNA is an endogenous danger signal that stimulates local synthesis and release of complement factor B","volume":"18","author":"Kaczorowski","year":"2012","journal-title":"Mol Med"},{"key":"2019052205002549600_cvy304-B16","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1038\/ncomms2023","article-title":"Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors","volume":"3","author":"Kurashima","year":"2012","journal-title":"Nat Commun"},{"key":"2019052205002549600_cvy304-B17","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1093\/cvr\/cvs018","article-title":"The innate immune response in reperfused myocardium","volume":"94","author":"Timmers","year":"2012","journal-title":"Cardiovasc Res"},{"key":"2019052205002549600_cvy304-B18","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1253\/circj.72.1178","article-title":"Effects of HMGB1 on ischemia-reperfusion injury in the rat heart","volume":"72","author":"Oozawa","year":"2008","journal-title":"Circ J"},{"key":"2019052205002549600_cvy304-B19","doi-asserted-by":"crossref","first-page":"302","DOI":"10.3389\/fimmu.2016.00302","article-title":"New insights into neutrophil extracellular traps: mechanisms of formation and role in inflammation","volume":"7","author":"Yang","year":"2016","journal-title":"Front Immunol"},{"key":"2019052205002549600_cvy304-B20","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1161\/CIRCRESAHA.116.304944","article-title":"Coronary neutrophil extracellular trap burden and deoxyribonuclease activity in ST-elevation acute coronary syndrome are predictors of ST-segment resolution and infarct size","volume":"116","author":"Mangold","year":"2015","journal-title":"Circ Res"},{"key":"2019052205002549600_cvy304-B21","doi-asserted-by":"crossref","first-page":"e32366.","DOI":"10.1371\/journal.pone.0032366","article-title":"Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones","volume":"7","author":"Saffarzadeh","year":"2012","journal-title":"PLoS One"},{"key":"2019052205002549600_cvy304-B22","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1111\/1440-1681.12602","article-title":"The role of Toll-like receptor 4 (TLR4) in cardiac ischaemic-reperfusion injury, cardioprotection and preconditioning","volume":"43","author":"Lee","year":"2016","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"2019052205002549600_cvy304-B23","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1084\/jem.20112322","article-title":"Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo","volume":"209","author":"von Bruhl","year":"2012","journal-title":"J Exp Med"},{"key":"2019052205002549600_cvy304-B24","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1160\/th14-08-0703","article-title":"RNase1 prevents the damaging interplay between extracellular RNA and tumour necrosis factor-alpha in cardiac ischaemia\/reperfusion injury","volume":"112","author":"Cabrera-Fuentes","year":"2014","journal-title":"Thromb Haemost"},{"key":"2019052205002549600_cvy304-B25","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.yjmcc.2013.04.023","article-title":"Temporal dynamics of cardiac immune cell accumulation following acute myocardial infarction","volume":"62","author":"Yan","year":"2013","journal-title":"J Mol Cell Cardiol"},{"key":"2019052205002549600_cvy304-B26","doi-asserted-by":"crossref","first-page":"e36814.","DOI":"10.1371\/journal.pone.0036814","article-title":"An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile","volume":"7","author":"Pinto","year":"2012","journal-title":"PLoS One"},{"key":"2019052205002549600_cvy304-B27","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1038\/s41591-018-0059-x","article-title":"The human heart contains distinct macrophage subsets with divergent origins and functions","volume":"24","author":"Bajpai","year":"2018","journal-title":"Nat Med"},{"key":"2019052205002549600_cvy304-B28","doi-asserted-by":"crossref","first-page":"e34730.","DOI":"10.1371\/journal.pone.0034730","article-title":"Resident cardiac immune cells and expression of the ectonucleotidase enzymes CD39 and CD73 after ischemic injury","volume":"7","author":"Bonner","year":"2012","journal-title":"PLoS One"},{"key":"2019052205002549600_cvy304-B29","doi-asserted-by":"crossref","first-page":"e0150606.","DOI":"10.1371\/journal.pone.0150606","article-title":"A protocol for the comprehensive flow cytometric analysis of immune cells in normal and inflamed murine non-lymphoid tissues","volume":"11","author":"Yu","year":"2016","journal-title":"PLoS One"},{"key":"2019052205002549600_cvy304-B30","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/978-1-4939-1568-2_8","article-title":"The emerging prominence of the cardiac mast cell as a potent mediator of adverse myocardial remodeling","volume":"1220","author":"Janicki","year":"2015","journal-title":"Methods Mol Biol"},{"key":"2019052205002549600_cvy304-B31","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1177\/0192623311436177","article-title":"Immunophenotypic alterations in resident immune cells and myocardial fibrosis in the aging rhesus macaque (Macaca mulatta) heart","volume":"40","author":"Macri","year":"2012","journal-title":"Toxicol Pathol"},{"key":"2019052205002549600_cvy304-B32","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1161\/01.CIR.98.7.699","article-title":"Resident cardiac mast cells degranulate and release preformed TNF-alpha, initiating the cytokine cascade in experimental canine myocardial ischemia\/reperfusion","volume":"98","author":"Frangogiannis","year":"1998","journal-title":"Circulation"},{"key":"2019052205002549600_cvy304-B33","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1177\/039463200702000108","article-title":"Mast cell deficient W\/Wv mice have lower serum IL-6 and less cardiac tissue necrosis than their normal littermates following myocardial ischemia-reperfusion","volume":"20","author":"Bhattacharya","year":"2007","journal-title":"Int J Immunopathol Pharmacol"},{"key":"2019052205002549600_cvy304-B34","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1007\/s00011-014-0763-z","article-title":"The role of mast cells in ischemia and reperfusion injury","volume":"63","author":"Yang","year":"2014","journal-title":"Inflamm Res"},{"key":"2019052205002549600_cvy304-B35","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s00395-017-0652-z","article-title":"Dual inhibition of cathepsin G and chymase reduces myocyte death and improves cardiac remodeling after myocardial ischemia reperfusion injury","volume":"112","author":"Hooshdaran","year":"2017","journal-title":"Basic Res Cardiol"},{"key":"2019052205002549600_cvy304-B36","doi-asserted-by":"crossref","first-page":"H1825","DOI":"10.1152\/ajpheart.495.2008","article-title":"Adenosine A2A receptor activation reduces infarct size in the isolated, perfused mouse heart by inhibiting resident cardiac mast cell degranulation","volume":"295","author":"Rork","year":"2008","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2019052205002549600_cvy304-B37","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1093\/cvr\/cvq272","article-title":"Cardiac mast cells: the centrepiece in adverse myocardial remodelling","volume":"89","author":"Levick","year":"2011","journal-title":"Cardiovasc Res"},{"key":"2019052205002549600_cvy304-B38","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.yjmcc.2006.09.020","article-title":"Insights from knock-out models concerning postischemic release of TNFalpha from isolated mouse hearts","volume":"42","author":"Reil","year":"2007","journal-title":"J Mol Cell Cardiol"},{"key":"2019052205002549600_cvy304-B39","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1007\/BF00788727","article-title":"Mast cell degranulation does not contribute to ischemic preconditioning in isolated rabbit hearts","volume":"91","author":"Wang","year":"1996","journal-title":"Basic Res Cardiol"},{"key":"2019052205002549600_cvy304-B40","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1097\/00005344-199805000-00018","article-title":"Cardiac mast cell stabilization and cardioprotective effect of ischemic preconditioning in isolated rat heart","volume":"31","author":"Parikh","year":"1998","journal-title":"J Cardiovasc Pharmacol"},{"key":"2019052205002549600_cvy304-B41","doi-asserted-by":"crossref","first-page":"480","DOI":"10.3389\/fimmu.2016.00480","article-title":"Immune regulation by pericytes: modulating innate and adaptive immunity","volume":"7","author":"Navarro","year":"2016","journal-title":"Front Immunol"},{"key":"2019052205002549600_cvy304-B42","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/ni.2477","article-title":"Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and \u2018instruct\u2019 them with pattern-recognition and motility programs","volume":"14","author":"Stark","year":"2013","journal-title":"Nat Immunol"},{"key":"2019052205002549600_cvy304-B43","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.29280","article-title":"Capillary pericytes mediate coronary no-reflow after myocardial ischaemia","volume":"6","author":"O'Farrell","year":"2017","journal-title":"Elife"},{"key":"2019052205002549600_cvy304-B44","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1126\/science.1071059","article-title":"The danger model: a renewed sense of self","volume":"296","author":"Matzinger","year":"2002","journal-title":"Science"},{"key":"2019052205002549600_cvy304-B45","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1038\/nri1372","article-title":"Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses","volume":"4","author":"Seong","year":"2004","journal-title":"Nat Rev Immunol"},{"key":"2019052205002549600_cvy304-B46","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S0008-6363(99)00012-7","article-title":"Myocardial injury leads to a release of heat shock protein (hsp) 60 and a suppression of the anti-hsp65 immune response","volume":"42","author":"Schett","year":"1999","journal-title":"Cardiovasc Res"},{"key":"2019052205002549600_cvy304-B47","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1161\/CIRCRESAHA.109.209643","article-title":"Extracellular heat shock protein 60, cardiac myocytes, and apoptosis","volume":"105","author":"Kim","year":"2009","journal-title":"Circ Res"},{"key":"2019052205002549600_cvy304-B48","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.yrtph.2017.07.028","article-title":"Exogenous administration of mitochondrial DNA promotes ischemia reperfusion injury via TLR9-p38 MAPK pathway","volume":"89","author":"Xie","year":"2017","journal-title":"Regul Toxicol Pharmacol"},{"key":"2019052205002549600_cvy304-B49","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/nature10992","article-title":"Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure","volume":"485","author":"Oka","year":"2012","journal-title":"Nature"},{"key":"2019052205002549600_cvy304-B50","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1097\/01.shk.0000209540.99176.72","article-title":"Elevated high-mobility group box 1 levels in patients with cerebral and myocardial ischemia","volume":"25","author":"Goldstein","year":"2006","journal-title":"Shock"},{"key":"2019052205002549600_cvy304-B51","doi-asserted-by":"crossref","first-page":"7370","DOI":"10.1074\/jbc.M306793200","article-title":"Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein","volume":"279","author":"Park","year":"2004","journal-title":"J Biol Chem"},{"key":"2019052205002549600_cvy304-B52","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/ni1457","article-title":"Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE","volume":"8","author":"Tian","year":"2007","journal-title":"Nat Immunol"},{"key":"2019052205002549600_cvy304-B53","doi-asserted-by":"crossref","first-page":"3216","DOI":"10.1161\/CIRCULATIONAHA.108.769331","article-title":"High-mobility group box-1 in ischemia-reperfusion injury of the heart","volume":"117","author":"Andrassy","year":"2008","journal-title":"Circulation"},{"key":"2019052205002549600_cvy304-B54","doi-asserted-by":"crossref","first-page":"64534","DOI":"10.18632\/oncotarget.17885","article-title":"The dual role and therapeutic potential of high-mobility group box 1 in cancer","volume":"8","author":"He","year":"2017","journal-title":"Oncotarget"},{"key":"2019052205002549600_cvy304-B55","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s00441-005-0144-6","article-title":"Extracellular matrix remodeling in canine and mouse myocardial infarcts","volume":"324","author":"Dobaczewski","year":"2006","journal-title":"Cell Tissue Res"},{"key":"2019052205002549600_cvy304-B56","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.4049\/jimmunol.181.3.2103","article-title":"Low molecular weight hyaluronic acid increases the self-defense of skin epithelium by induction of beta-defensin 2 via TLR2 and TLR4","volume":"181","author":"Gariboldi","year":"2008","journal-title":"J Immunol"},{"key":"2019052205002549600_cvy304-B57","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1038\/nm1315","article-title":"Regulation of lung injury and repair by Toll-like receptors and hyaluronan","volume":"11","author":"Jiang","year":"2005","journal-title":"Nat Med"},{"key":"2019052205002549600_cvy304-B58","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.atherosclerosis.2007.08.004","article-title":"Atherosclerotic lesion development and Toll like receptor 2 and 4 responsiveness","volume":"197","author":"Schoneveld","year":"2008","journal-title":"Atherosclerosis"},{"key":"2019052205002549600_cvy304-B59","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1161\/CIRCRESAHA.110.224428","article-title":"Lack of fibronectin-EDA promotes survival and prevents adverse remodeling and heart function deterioration after myocardial infarction","volume":"108","author":"Arslan","year":"2011","journal-title":"Circ Res"},{"key":"2019052205002549600_cvy304-B60","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1172\/JCI6709","article-title":"Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium","volume":"104","author":"Frantz","year":"1999","journal-title":"J Clin Invest"},{"key":"2019052205002549600_cvy304-B61","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.coph.2012.06.002","article-title":"New developments in Toll-like receptor targeted therapeutics","volume":"12","author":"Connolly","year":"2012","journal-title":"Curr Opin Pharmacol"},{"key":"2019052205002549600_cvy304-B62","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1161\/CIRCINTERVENTIONS.111.967596","article-title":"Treatment with OPN-305, a humanized anti-Toll-Like receptor-2 antibody, reduces myocardial ischemia\/reperfusion injury in pigs","volume":"5","author":"Arslan","year":"2012","journal-title":"Circ Cardiovasc Interv"},{"key":"2019052205002549600_cvy304-B63","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1161\/CIRCULATIONAHA.109.880187","article-title":"Myocardial ischemia\/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibody","volume":"121","author":"Arslan","year":"2010","journal-title":"Circulation"},{"key":"2019052205002549600_cvy304-B64","doi-asserted-by":"crossref","first-page":"H1079","DOI":"10.1152\/ajpheart.00306.2009","article-title":"Innate immunity mediates myocardial preconditioning through Toll-like receptor 2 and TIRAP-dependent signaling pathways","volume":"298","author":"Dong","year":"2010","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2019052205002549600_cvy304-B65","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.bbadis.2013.10.006","article-title":"Toll-like receptor 3 plays a role in myocardial infarction and ischemia\/reperfusion injury","volume":"1842","author":"Lu","year":"2014","journal-title":"Biochim Biophys Acta"},{"key":"2019052205002549600_cvy304-B66","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.gene.2013.05.041","article-title":"The HMGB1-TLR4 axis contributes to myocardial ischemia\/reperfusion injury via regulation of cardiomyocyte apoptosis","volume":"527","author":"Ding","year":"2013","journal-title":"Gene"},{"key":"2019052205002549600_cvy304-B67","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1161\/01.CIR.0000112575.66565.84","article-title":"Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice","volume":"109","author":"Oyama","year":"2004","journal-title":"Circulation"},{"key":"2019052205002549600_cvy304-B68","doi-asserted-by":"crossref","first-page":"I270","DOI":"10.1161\/CIRCULATIONAHA.105.000901","article-title":"Inhibition of Toll-like receptor 4 with eritoran attenuates myocardial ischemia-reperfusion injury","volume":"114","author":"Shimamoto","year":"2006","journal-title":"Circulation"},{"key":"2019052205002549600_cvy304-B69","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/nature02664","article-title":"Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf","volume":"430","author":"Mariathasan","year":"2004","journal-title":"Nature"},{"key":"2019052205002549600_cvy304-B70","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S1097-2765(02)00599-3","article-title":"The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta","volume":"10","author":"Martinon","year":"2002","journal-title":"Mol Cell"},{"key":"2019052205002549600_cvy304-B71","doi-asserted-by":"crossref","first-page":"R568","DOI":"10.1016\/j.cub.2016.02.019","article-title":"Pyroptosis","volume":"26","author":"Vande Walle","year":"2016","journal-title":"Curr Biol"},{"key":"2019052205002549600_cvy304-B72","doi-asserted-by":"crossref","first-page":"19725","DOI":"10.1073\/pnas.1108586108","article-title":"The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse","volume":"108","author":"Mezzaroma","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"2019052205002549600_cvy304-B73","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1177\/1074248417702890","article-title":"The highly selective caspase-1 inhibitor VX-765 provides additive protection against myocardial infarction in rat hearts when combined with a platelet inhibitor","volume":"22","author":"Yang","year":"2017","journal-title":"J Cardiovasc Pharmacol Ther"},{"key":"2019052205002549600_cvy304-B74","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s10557-018-6781-2","article-title":"The caspase 1 inhibitor VX-765 protects the isolated rat heart via the RISK pathway","volume":"32","author":"Do Carmo","year":"2018","journal-title":"Cardiovasc Drugs Ther"},{"key":"2019052205002549600_cvy304-B75","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1161\/CIRCULATIONAHA.110.982777","article-title":"Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia\/reperfusion injury","volume":"123","author":"Kawaguchi","year":"2011","journal-title":"Circulation"},{"key":"2019052205002549600_cvy304-B76","doi-asserted-by":"crossref","first-page":"e40643.","DOI":"10.1371\/journal.pone.0040643","article-title":"Deletion of the innate immune NLRP3 receptor abolishes cardiac ischemic preconditioning and is associated with decreased IL-6\/STAT3 signaling","volume":"7","author":"Zuurbier","year":"2012","journal-title":"PLoS One"},{"key":"2019052205002549600_cvy304-B77","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1093\/cvr\/cvt091","article-title":"The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury","volume":"99","author":"Sandanger","year":"2013","journal-title":"Cardiovasc Res"},{"key":"2019052205002549600_cvy304-B78","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s00395-014-0415-z","article-title":"TXNIP mediates NLRP3 inflammasome activation in cardiac microvascular endothelial cells as a novel mechanism in myocardial ischemia\/reperfusion injury","volume":"109","author":"Liu","year":"2014","journal-title":"Basic Res Cardiol"},{"key":"2019052205002549600_cvy304-B79","doi-asserted-by":"crossref","first-page":"5271251.","DOI":"10.1155\/2016\/5271251","article-title":"Pharmacological inhibition of NLRP3 inflammasome attenuates myocardial ischemia\/reperfusion injury by activation of RISK and mitochondrial pathways","volume":"2016","author":"Mastrocola","year":"2016","journal-title":"Oxid Med Cell Longev"},{"key":"2019052205002549600_cvy304-B80","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.ijcard.2014.09.148","article-title":"Nlrp3 plays no role in acute cardiac infarction due to low cardiac expression","volume":"177","author":"Jong","year":"2014","journal-title":"Int J Cardiol"},{"key":"2019052205002549600_cvy304-B81","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1097\/FJC.0000000000000053","article-title":"A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia-reperfusion in the mouse","volume":"63","author":"Marchetti","year":"2014","journal-title":"J Cardiovasc Pharmacol"},{"key":"2019052205002549600_cvy304-B82","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.ijcard.2016.02.043","article-title":"Inhibition of the NLRP3 inflammasome limits the inflammatory injury following myocardial ischemia-reperfusion in the mouse","volume":"209","author":"Toldo","year":"2016","journal-title":"Int J Cardiol"},{"key":"2019052205002549600_cvy304-B83","first-page":"828","article-title":"The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction","volume":"38","author":"van Hout","year":"2017","journal-title":"Eur Heart J"},{"key":"2019052205002549600_cvy304-B84","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1016\/j.bbrc.2015.12.051","article-title":"NLRP3 inflammasome activation during myocardial ischemia reperfusion is cardioprotective","volume":"469","author":"Sandanger","year":"2016","journal-title":"Biochem Biophys Res Commun"},{"key":"2019052205002549600_cvy304-B85","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1084\/jem.20161031","article-title":"NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity","volume":"214","author":"Stokman","year":"2017","journal-title":"J Exp Med"},{"key":"2019052205002549600_cvy304-B86","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1038\/nrd.2018.97","article-title":"Targeting the NLRP3 inflammasome in inflammatory diseases","volume":"17","author":"Mangan","year":"2018","journal-title":"Nat Rev Drug Discov"},{"key":"2019052205002549600_cvy304-B87","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1152\/japplphysiol.00436.2005","article-title":"Short-term hyperglycemia increases endothelial glycocalyx permeability and acutely decreases lineal density of capillaries with flowing red blood cells","volume":"99","author":"Zuurbier","year":"2005","journal-title":"J Appl Physiol (1985)"},{"key":"2019052205002549600_cvy304-B88","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1016\/j.biopha.2016.10.073","article-title":"MicroRNAs regulate mitochondrial apoptotic pathway in myocardial ischemia-reperfusion-injury","volume":"84","author":"Makhdoumi","year":"2016","journal-title":"Biomed Pharmacother"},{"key":"2019052205002549600_cvy304-B89","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1111\/bph.12363","article-title":"Targeting hexokinase II to mitochondria to modulate energy metabolism and reduce ischaemia-reperfusion injury in heart","volume":"171","author":"Nederlof","year":"2014","journal-title":"Br J Pharmacol"},{"key":"2019052205002549600_cvy304-B90","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.1016\/j.celrep.2018.07.098","article-title":"A membrane potential- and calpain-dependent reversal of caspase-1 inhibition regulates canonical NLRP3 inflammasome","volume":"24","author":"Zhang","year":"2018","journal-title":"Cell Rep"},{"key":"2019052205002549600_cvy304-B91","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/nature18629","article-title":"Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores","volume":"535","author":"Liu","year":"2016","journal-title":"Nature"},{"key":"2019052205002549600_cvy304-B92","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1038\/nature15514","article-title":"Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death","volume":"526","author":"Shi","year":"2015","journal-title":"Nature"},{"key":"2019052205002549600_cvy304-B93","doi-asserted-by":"crossref","first-page":"3001","DOI":"10.1038\/s41467-018-05321-2","article-title":"SUMO-mediated regulation of NLRP3 modulates inflammasome activity","volume":"9","author":"Barry","year":"2018","journal-title":"Nat Commun"},{"key":"2019052205002549600_cvy304-B94","doi-asserted-by":"crossref","first-page":"9792","DOI":"10.1074\/jbc.M109.082305","article-title":"Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome","volume":"285","author":"Juliana","year":"2010","journal-title":"J Biol Chem"},{"key":"2019052205002549600_cvy304-B95","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1536\/ihj.51.348","article-title":"BAY 11-7082, a nuclear factor-\u03baB inhibitor, reduces inflammation and apoptosis in a rat cardiac ischemia-reperfusion injury model","volume":"51","author":"Kim","year":"2010","journal-title":"Int Heart J"},{"key":"2019052205002549600_cvy304-B96","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1002\/cmdc.201600055","article-title":"Design, synthesis, and evaluation of acrylamide derivatives as direct NLRP3 inflammasome inhibitors","volume":"11","author":"Cocco","year":"2016","journal-title":"ChemMedChem"},{"key":"2019052205002549600_cvy304-B97","doi-asserted-by":"crossref","first-page":"E1530","DOI":"10.1073\/pnas.1716095115","article-title":"OLT1177, a beta-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation","volume":"115","author":"Marchetti","year":"2018","journal-title":"Proc Natl Acad Sci USA"},{"key":"2019052205002549600_cvy304-B98","article-title":"Novel NLRP3 inflammasome inhibitor OLT1177 reduces infarct size in a mouse model of myocardial ischemia reperfusion injury","volume":"136","author":"Toldo","year":"2018","journal-title":"Circulation"},{"key":"2019052205002549600_cvy304-B99","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1038\/ni.2639","article-title":"CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation","volume":"14","author":"Sheedy","year":"2013","journal-title":"Nat Immunol"},{"key":"2019052205002549600_cvy304-B100","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1038\/nature08938","article-title":"NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals","volume":"464","author":"Duewell","year":"2010","journal-title":"Nature"},{"key":"2019052205002549600_cvy304-B101","doi-asserted-by":"crossref","first-page":"6119","DOI":"10.4049\/jimmunol.1002843","article-title":"Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway","volume":"186","author":"Niemi","year":"2011","journal-title":"J Immunol"},{"key":"2019052205002549600_cvy304-B102","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1038\/ni.2022","article-title":"Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling","volume":"12","author":"Wen","year":"2011","journal-title":"Nat Immunol"},{"key":"2019052205002549600_cvy304-B103","doi-asserted-by":"crossref","first-page":"4331","DOI":"10.4049\/jimmunol.1502340","article-title":"The receptor for advanced glycation end products activates the AIM2 inflammasome in acute pancreatitis","volume":"196","author":"Kang","year":"2016","journal-title":"J Immunol"},{"key":"2019052205002549600_cvy304-B104","doi-asserted-by":"crossref","first-page":"e0172575.","DOI":"10.1371\/journal.pone.0172575","article-title":"Microvesicles released from fat-laden cells promote activation of hepatocellular NLRP3 inflammasome: a pro-inflammatory link between lipotoxicity and non-alcoholic steatohepatitis","volume":"12","author":"Cannito","year":"2017","journal-title":"PLoS One"},{"key":"2019052205002549600_cvy304-B105","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.2174\/0929867324666170407123522","article-title":"Metaflammation: tissue-specific alterations of the NLRP3 inflammasome platform in metabolic syndrome","volume":"25","author":"Mastrocola","year":"2018","journal-title":"CMC"},{"key":"2019052205002549600_cvy304-B106","doi-asserted-by":"crossref","first-page":"678627.","DOI":"10.1155\/2013\/678627","article-title":"The NLRP3 inflammasome as a novel player of the intercellular crosstalk in metabolic disorders","volume":"2013","author":"Benetti","year":"2013","journal-title":"Mediators Inflamm"},{"key":"2019052205002549600_cvy304-B107","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.atherosclerosis.2015.07.043","article-title":"Expression of NLRP3 in subcutaneous adipose tissue is associated with coronary atherosclerosis","volume":"242","author":"Bando","year":"2015","journal-title":"Atherosclerosis"},{"key":"2019052205002549600_cvy304-B108","doi-asserted-by":"crossref","first-page":"3480637.","DOI":"10.1155\/2016\/3480637","article-title":"Maladaptive modulations of NLRP3 inflammasome and cardioprotective pathways are involved in diet-induced exacerbation of myocardial ischemia\/reperfusion injury in mice","volume":"2016","author":"Mastrocola","year":"2016","journal-title":"Oxid Med Cell Longev"},{"key":"2019052205002549600_cvy304-B109","first-page":"1.","article-title":"Inhibition of NLRP3 inflammasome ameliorates cerebral ischemia-reperfusion injury in diabetic mice","volume":"2018","author":"Hong","year":"2018","journal-title":"Neural Plast"},{"key":"2019052205002549600_cvy304-B110","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.immuni.2012.01.009","article-title":"Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis","volume":"36","author":"Shimada","year":"2012","journal-title":"Immunity"},{"key":"2019052205002549600_cvy304-B111","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00395-014-0459-0","article-title":"Mitochondrially targeted Endonuclease III has a powerful anti-infarct effect in an in vivo rat model of myocardial ischemia\/reperfusion","volume":"110","author":"Yang","year":"2015","journal-title":"Basic Res Cardiol"},{"key":"2019052205002549600_cvy304-B112","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/imr.12293","article-title":"The NAIP-NLRC4 inflammasome in innate immune detection of bacterial flagellin and type III secretion apparatus","volume":"265","author":"Zhao","year":"2015","journal-title":"Immunol Rev"},{"key":"2019052205002549600_cvy304-B113","doi-asserted-by":"crossref","first-page":"36321","DOI":"10.1074\/jbc.M708182200","article-title":"The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock","volume":"282","author":"Shao","year":"2007","journal-title":"J Biol Chem"},{"key":"2019052205002549600_cvy304-B114","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1073\/pnas.041611398","article-title":"Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1\u03b2","volume":"98","author":"Pomerantz","year":"2001","journal-title":"Proc Natl Acad Sci USA"},{"key":"2019052205002549600_cvy304-B115","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/s00395-018-0692-z","article-title":"Caspase-1 inhibition by VX-765 administered at reperfusion in P2Y12 receptor antagonist-treated rats provides long-term reduction in myocardial infarct size and preservation of ventricular function","volume":"113","author":"Audia","year":"2018","journal-title":"Basic Res Cardiol"},{"key":"2019052205002549600_cvy304-B116","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1161\/CIRCULATIONAHA.116.024014","article-title":"Protective effects of ticagrelor on myocardial injury after infarction","volume":"134","author":"Vilahur","year":"2016","journal-title":"Circulation"},{"key":"2019052205002549600_cvy304-B117","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1161\/ATVBAHA.115.305655","article-title":"Ticagrelor protects the heart against reperfusion injury and improves remodeling after myocardial infarction","volume":"35","author":"Ye","year":"2015","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"2019052205002549600_cvy304-B118","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s10557-013-6474-9","article-title":"Triple therapy greatly increases myocardial salvage during ischemia\/reperfusion in the in situ rat heart","volume":"27","author":"Yang","year":"2013","journal-title":"Cardiovasc Drugs Ther"},{"key":"2019052205002549600_cvy304-B119","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1093\/cvr\/cvy314","article-title":"Circulating blood cells and extracellular vesicles in acute cardioprotection","volume":"115","author":"Davidson","year":"2019","journal-title":"Cardiovasc Res"},{"key":"2019052205002549600_cvy304-B120","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1124\/pr.113.008300","article-title":"Interaction of risk factors, comorbidities, and comedications with ischemia\/reperfusion injury and cardioprotection by preconditioning, postconditioning, and remote conditioning","volume":"66","author":"Ferdinandy","year":"2014","journal-title":"Pharmacol Rev"},{"key":"2019052205002549600_cvy304-B121","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1093\/cvr\/cvu225","article-title":"ESC working group cellular biology of the heart: position paper: improving the preclinical assessment of novel cardioprotective therapies","volume":"104","author":"Lecour","year":"2014","journal-title":"Cardiovasc Res"},{"key":"2019052205002549600_cvy304-B122","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3389\/fendo.2017.00072","article-title":"Diabetic cardiomyopathy: an immunometabolic perspective","volume":"8","author":"Mishra","year":"2017","journal-title":"Front Endocrinol (Lausanne"},{"key":"2019052205002549600_cvy304-B123","doi-asserted-by":"crossref","first-page":"aaf1098.","DOI":"10.1126\/science.aaf1098","article-title":"Trained immunity: a program of innate immune memory in health and disease","volume":"352","author":"Netea","year":"2016","journal-title":"Science"},{"key":"2019052205002549600_cvy304-B124","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.molimm.2015.06.019","article-title":"Trained immunity: a smart way to enhance innate immune defence","volume":"68","author":"van der Meer","year":"2015","journal-title":"Mol Immunol"},{"key":"2019052205002549600_cvy304-B125","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.cardiores.2003.09.007","article-title":"Modulating Toll-like receptor mediated signaling by (1\u2013>3)-beta-D-glucan rapidly induces cardioprotection","volume":"61","author":"Li","year":"2004","journal-title":"Cardiovasc Res"},{"key":"2019052205002549600_cvy304-B126","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1038\/aps.2009.102","article-title":"Protective effects of betaglucin on myocardial tissue during myocardial infarction in rats and dogs","volume":"30","author":"Qian","year":"2009","journal-title":"Acta Pharmacol Sin"},{"key":"2019052205002549600_cvy304-B127","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/nri3042","article-title":"Reciprocal regulation of the neural and innate immune systems","volume":"11","author":"Irwin","year":"2011","journal-title":"Nat Rev Immunol"},{"key":"2019052205002549600_cvy304-B128","doi-asserted-by":"crossref","first-page":"14780.","DOI":"10.1038\/ncomms14780","article-title":"Neutrophil stunning by metoprolol reduces infarct size","volume":"8","author":"Garcia-Prieto","year":"2017","journal-title":"Nat Commun"},{"key":"2019052205002549600_cvy304-B129","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1056\/NEJMoa1109400","article-title":"Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk","volume":"368","author":"Tang","year":"2013","journal-title":"N Engl J Med"},{"key":"2019052205002549600_cvy304-B130","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1182\/blood-2016-11-754416","article-title":"Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2","volume":"130","author":"Jackel","year":"2017","journal-title":"Blood"},{"key":"2019052205002549600_cvy304-B131","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1161\/ATVBAHA.118.311023","article-title":"Gut microbiota-dependent trimethylamine n-oxide predicts risk of cardiovascular events in patients with stroke and is related to proinflammatory monocytes","volume":"38","author":"Haghikia","year":"2018","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"2019052205002549600_cvy304-B132","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/s40168-018-0441-4","article-title":"Gut-dependent microbial translocation induces inflammation and cardiovascular events after ST-elevation myocardial infarction","volume":"6","author":"Zhou","year":"2018","journal-title":"Microbiome"},{"key":"2019052205002549600_cvy304-B133","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1056\/NEJMoa1707914","article-title":"Antiinflammatory therapy with canakinumab for atherosclerotic disease","volume":"377","author":"Ridker","year":"2017","journal-title":"N Engl J Med"},{"key":"2019052205002549600_cvy304-B134","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1093\/cvr\/cvy145","article-title":"Immunomodulatory interventions in myocardial infarction and heart failure: a systematic review of clinical trials and meta-analysis of IL-1 inhibition","volume":"114","author":"Panahi","year":"2018","journal-title":"Cardiovasc Res"}],"container-title":["Cardiovascular Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cardiovascres\/article-pdf\/115\/7\/1131\/28679730\/cvy304.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T17:44:59Z","timestamp":1605635099000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cardiovascres\/article\/115\/7\/1131\/5255892"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,21]]},"references-count":134,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2018,12,21]]},"published-print":{"date-parts":[[2019,6,1]]}},"URL":"https:\/\/doi.org\/10.1093\/cvr\/cvy304","relation":{},"ISSN":["0008-6363","1755-3245"],"issn-type":[{"value":"0008-6363","type":"print"},{"value":"1755-3245","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,6,1]]},"published":{"date-parts":[[2018,12,21]]}}}