{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:16:36Z","timestamp":1790705796531,"version":"4.1.0"},"reference-count":161,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2019,2,23]],"date-time":"2019-02-23T00:00:00Z","timestamp":1550880000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"National Institute for Health Research University College London Hospitals Biomedical Research Centre"},{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","award":["FS\/10\/039\/28270"],"award-info":[{"award-number":["FS\/10\/039\/28270"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","award":["FS\/12\/2\/29300"],"award-info":[{"award-number":["FS\/12\/2\/29300"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","award":["PG\/13\/57\/30385"],"award-info":[{"award-number":["PG\/13\/57\/30385"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","award":["RG\/17\/3\/32774"],"award-info":[{"award-number":["RG\/17\/3\/32774"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Duke-National University Singapore Medical School"},{"name":"Singapore Ministry of Health\u2019s National Medical Research Council"},{"name":"Clinician Scientist-Senior Investigator","award":["NMRC\/CSA-SI\/0011\/2017"],"award-info":[{"award-number":["NMRC\/CSA-SI\/0011\/2017"]}]},{"name":"Collaborative Centre Grant","award":["NMRC\/CGAug16C006"],"award-info":[{"award-number":["NMRC\/CGAug16C006"]}]},{"name":"Singapore Ministry of Education Academic Research Fund Tier 2","award":["MOE2016-T2-2-021"],"award-info":[{"award-number":["MOE2016-T2-2-021"]}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"name":"CIBERCV-Instituto de Salud Carlos III","award":["CB16\/11\/00479"],"award-info":[{"award-number":["CB16\/11\/00479"]}]},{"name":"European Regional Development Fund-FEDER","award":["PIE\/2013-00047"],"award-info":[{"award-number":["PIE\/2013-00047"]}]},{"name":"European Regional Development Fund-FEDER","award":["PI 17\/1397"],"award-info":[{"award-number":["PI 17\/1397"]}]},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["SFB 1116"],"award-info":[{"award-number":["SFB 1116"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007398","name":"Danish Council for Strategic Research","doi-asserted-by":"publisher","award":["11-108354"],"award-info":[{"award-number":["11-108354"]}],"id":[{"id":"10.13039\/100007398","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Conditioning Based Intervention Strategies \u2013 ConBis"},{"name":"National Research, Development and Innovation Office of Hungary","award":["NVKP_16-1-2016-0017"],"award-info":[{"award-number":["NVKP_16-1-2016-0017"]}]},{"name":"National Research, Development and Innovation Office of Hungary","award":["OTKA KH 125570"],"award-info":[{"award-number":["OTKA KH 125570"]}]},{"name":"National Research, Development and Innovation Office of Hungary","award":["OTKA 115378"],"award-info":[{"award-number":["OTKA 115378"]}]},{"name":"Higher Education Institutional Excellence Programme of the Ministry of Human Capacities in Hungary"},{"name":"Therapeutic Development"},{"DOI":"10.13039\/501100002332","name":"Semmelweis University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002332","id-type":"DOI","asserted-by":"publisher"}]},{"name":"COST Action EU-CARDIOPROTECTION","award":["CA16225"],"award-info":[{"award-number":["CA16225"]}]},{"DOI":"10.13039\/501100000921","name":"European Cooperation in Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000921","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,6,1]]},"DOI":"10.1093\/cvr\/cvz053","type":"journal-article","created":{"date-parts":[[2019,2,21]],"date-time":"2019-02-21T07:13:53Z","timestamp":1550733233000},"page":"1167-1177","source":"Crossref","is-referenced-by-count":55,"title":["Cardiac innervation in acute myocardial ischaemia\/reperfusion injury and cardioprotection"],"prefix":"10.1093","volume":"115","author":[{"given":"Derek J","family":"Hausenloy","sequence":"first","affiliation":[{"name":"Cardiovascular & Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore"},{"name":"National Heart Research Institute Singapore, National Heart Centre, Singapore"},{"name":"Yong Loo Lin School of Medicine, National University Singapore, Singapore"},{"name":"The Hatter Cardiovascular Institute, University College London, London, UK"},{"name":"The National Institute of Health Research University College London Hospitals Biomedical Research Centre, Research & Development, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans Erik","family":"B\u00f8tker","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Aarhus University Hospital, Aarhus N, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Ferdinandy","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary"},{"name":"Pharmahungary Group, Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerd","family":"Heusch","sequence":"additional","affiliation":[{"name":"Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G Andr\u00e9","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Sciences, University of Leicester, NIHR Leicester Biomedical Research Centre, Glenfield Hospital, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Redington","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center, Heart Institute, Cincinnati, OH, USA"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Garcia-Dorado","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Vascular Biology and Metabolism Area, Vall d\u2019Hebron University Hospital and Research Institute (VHIR), Universitat Aut\u00f3noma de Barcelona, Spain"},{"name":"Instituto CIBER de Enfermedades Cardiovasculares (CIBERCV): Instituto de Salud Carlos III, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,2,23]]},"reference":[{"key":"2019052205004238900_cvz053-B1","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1113\/expphysiol.2007.041178","article-title":"Potential clinical relevance of the \u2018little brain\u2019 on the mammalian heart","volume":"93","author":"Armour","year":"2008","journal-title":"Exp Physiol"},{"key":"2019052205004238900_cvz053-B2","doi-asserted-by":"crossref","first-page":"508","DOI":"10.4330\/wjc.v9.i6.508","article-title":"Influence of cardiac nerve status on cardiovascular regulation and cardioprotection","volume":"9","author":"Kingma","year":"2017","journal-title":"World J Cardiol"},{"key":"2019052205004238900_cvz053-B3","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.autneu.2016.08.006","article-title":"Characterization of the intrinsic cardiac nervous system","volume":"199","author":"Wake","year":"2016","journal-title":"Auton Neurosci"},{"key":"2019052205004238900_cvz053-B4","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1016\/j.hrthm.2018.05.018","article-title":"The electrophysiological effects of nicotinic and electrical stimulation of intrinsic cardiac ganglia in the absence of extrinsic autonomic nerves in the rabbit heart","volume":"15","author":"Allen","year":"2018","journal-title":"Heart Rhythm"},{"key":"2019052205004238900_cvz053-B5","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0165-1838(94)00139-B","article-title":"The physiological and anatomical demonstration of functionally selective parasympathetic ganglia located in discrete fat pads on the feline myocardium","volume":"51","author":"Gatti","year":"1995","journal-title":"J Auton Nerv Syst"},{"key":"2019052205004238900_cvz053-B6","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.1152\/japplphysiol.00616.2003","article-title":"Parasympathetic control of the heart. II. A novel interganglionic intrinsic cardiac circuit mediates neural control of heart rate","volume":"96","author":"Gray","year":"2004","journal-title":"J Appl Physiol (1985)"},{"key":"2019052205004238900_cvz053-B7","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0165-1838(98)00048-4","article-title":"Parasympathetic neurons in the cranial medial ventricular fat pad on the dog heart selectively decrease ventricular contractility","volume":"70","author":"Dickerson","year":"1998","journal-title":"J Auton Nerv Syst"},{"key":"2019052205004238900_cvz053-B8","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.autneu.2011.08.004","article-title":"Differential cardiac responses to unilateral sympathetic nerve stimulation in the isolated innervated rabbit heart","volume":"166","author":"Winter","year":"2012","journal-title":"Auton Neurosci"},{"key":"2019052205004238900_cvz053-B9","doi-asserted-by":"crossref","first-page":"4515","DOI":"10.1113\/jphysiol.2013.259382","article-title":"Network interactions within the canine intrinsic cardiac nervous system: implications for reflex control of regional cardiac function","volume":"591","author":"Beaumont","year":"2013","journal-title":"J Physiol"},{"key":"2019052205004238900_cvz053-B10","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1007\/BF00175791","article-title":"Actions of calcitonin gene-related peptide and tachykinins in relation to the contractile effects of capsaicin in the guinea-pig and rat heart in vitro","volume":"337","author":"Franco-Cereceda","year":"1988","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"2019052205004238900_cvz053-B11","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0014-2999(03)02117-4","article-title":"Capsaicin-sensitive sensory neurons regulate myocardial nitric oxide and cGMP signaling","volume":"476","author":"Csont","year":"2003","journal-title":"Eur J Pharmacol"},{"key":"2019052205004238900_cvz053-B12","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1007\/PL00005062","article-title":"Capsaicin-sensitive local sensory innervation is involved in pacing-induced preconditioning in rat hearts: role of nitric oxide and CGRP?","volume":"356","author":"Ferdinandy","year":"1997","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"2019052205004238900_cvz053-B13","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1096\/fj.05-4060fje","article-title":"Capsaicin-sensitive sensory neurons regulate myocardial function and gene expression pattern of rat hearts: a DNA microarray study","volume":"20","author":"Zvara","year":"2006","journal-title":"FASEB J"},{"key":"2019052205004238900_cvz053-B14","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1038\/sj.bjp.0707599","article-title":"Cardiac capsaicin-sensitive sensory nerves regulate myocardial relaxation via S-nitrosylation of SERCA: role of peroxynitrite","volume":"153","author":"Bencsik","year":"2008","journal-title":"Br J Pharmacol"},{"key":"2019052205004238900_cvz053-B15","doi-asserted-by":"crossref","first-page":"3617","DOI":"10.1161\/CIRCULATIONAHA.105.556274","article-title":"TRPV1 gene knockout impairs postischemic recovery in isolated perfused heart in mice","volume":"112","author":"Wang","year":"2005","journal-title":"Circulation"},{"key":"2019052205004238900_cvz053-B16","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1007\/s00210-004-0985-7","article-title":"Selective sensory denervation by capsaicin aggravates adriamycin-induced cardiomyopathy in rats","volume":"370","author":"Katona","year":"2004","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"2019052205004238900_cvz053-B17","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1161\/HYPERTENSIONAHA.114.03699","article-title":"Cardiac sympathetic afferent denervation attenuates cardiac remodeling and improves cardiovascular dysfunction in rats with heart failure","volume":"64","author":"Wang","year":"2014","journal-title":"Hypertension"},{"key":"2019052205004238900_cvz053-B18","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1016\/j.jacc.2017.08.056","article-title":"Renal sympathetic denervation protects the failing heart via inhibition of neprilysin activity in the kidney","volume":"70","author":"Polhemus","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2019052205004238900_cvz053-B19","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1161\/CIRCRESAHA.107.165183","article-title":"Beneficial effect of the central nervous system beta-adrenoceptor blockade on the failing heart","volume":"102","author":"Gourine","year":"2008","journal-title":"Circ Res"},{"key":"2019052205004238900_cvz053-B20","doi-asserted-by":"crossref","first-page":"3853","DOI":"10.1113\/JP271840","article-title":"Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease","volume":"594","author":"Habecker","year":"2016","journal-title":"J Physiol (Lond)"},{"key":"2019052205004238900_cvz053-B21","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1523\/JNEUROSCI.23-02-00416.2003","article-title":"The second galanin receptor GalR2 plays a key role in neurite outgrowth from adult sensory neurons","volume":"23","author":"Mahoney","year":"2003","journal-title":"J Neurosci"},{"key":"2019052205004238900_cvz053-B22","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/s00259-015-3171-x","article-title":"Sympathetic nerve damage and restoration after ischemia-reperfusion injury as assessed by (11)C-hydroxyephedrine","volume":"43","author":"Werner","year":"2016","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"2019052205004238900_cvz053-B23","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.autneu.2013.10.008","article-title":"Dynamic remodeling of the guinea pig intrinsic cardiac plexus induced by chronic myocardial infarction","volume":"181","author":"Hardwick","year":"2014","journal-title":"Auton Neurosci"},{"key":"2019052205004238900_cvz053-B24","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1002\/1097-0185(20000801)259:4<424::AID-AR60>3.0.CO;2-J","article-title":"Pathology of intrinsic cardiac neurons from ischemic human hearts","volume":"259","author":"Hopkins","year":"2000","journal-title":"Anat Rec"},{"key":"2019052205004238900_cvz053-B25","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1113\/JP271165","article-title":"Myocardial infarction induces structural and functional remodelling of the intrinsic cardiac nervous system","volume":"594","author":"Rajendran","year":"2016","journal-title":"J Physiol (Lond)"},{"key":"2019052205004238900_cvz053-B26","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1161\/01.RES.78.4.573","article-title":"Transient ischemia reduces norepinephrine release during sustained ischemia. Neural preconditioning in isolated rat heart","volume":"78","author":"Seyfarth","year":"1996","journal-title":"Circ Res"},{"key":"2019052205004238900_cvz053-B27","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/S0022-2828(08)80058-2","article-title":"Intermittent v continuous ischemia decelerates adenylate breakdown and prevents norepinephrine release in reperfused rabbit heart","volume":"27","author":"de Jong","year":"1995","journal-title":"J Mol Cell Cardiol"},{"key":"2019052205004238900_cvz053-B28","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1161\/hc3501.093800","article-title":"Ischemic preconditioning attenuates cardiac sympathetic nerve injury via ATP-sensitive potassium channels during myocardial ischemia","volume":"104","author":"Miura","year":"2001","journal-title":"Circulation"},{"key":"2019052205004238900_cvz053-B29","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1093\/bja\/aes144","article-title":"Blockade of spinal nerves inhibits expression of neural growth factor in the myocardium at an early stage of acute myocardial infarction in rats","volume":"109","author":"Yue","year":"2012","journal-title":"Br J Anaesth"},{"key":"2019052205004238900_cvz053-B30","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1515\/jbcpp-2012-0045","article-title":"Nerve growth factor reduces myocardial ischemia\/reperfusion injury in rat hearts","volume":"24","author":"Strande","year":"2013","journal-title":"J Basic Clin Physiol Pharmacol"},{"key":"2019052205004238900_cvz053-B31","doi-asserted-by":"crossref","first-page":"H364","DOI":"10.1152\/ajpheart.00369.2016","article-title":"Sympathetic nervous response to ischemia-reperfusion injury in humans is altered with remote ischemic preconditioning","volume":"311","author":"Lambert","year":"2016","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2019052205004238900_cvz053-B32","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1136\/hrt.2010.209304","article-title":"Heart-brain interactions in cardiac arrhythmia","volume":"97","author":"Taggart","year":"2011","journal-title":"Heart"},{"key":"2019052205004238900_cvz053-B33","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/0165-1838(85)90020-7","article-title":"Cardiac sympathetic nerve activity and progressive vasoconstriction distal to coronary stenoses: feed-back aggravation of myocardial ischemia","volume":"13","author":"Heusch","year":"1985","journal-title":"J Auton Nerv Syst"},{"key":"2019052205004238900_cvz053-B34","doi-asserted-by":"crossref","first-page":"H2687","DOI":"10.1152\/ajpheart.00291.2002","article-title":"Disruption of vagal efferent axon and nerve terminal function in the postischemic myocardium","volume":"283","author":"Kawada","year":"2002","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2019052205004238900_cvz053-B35","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1093\/cvr\/8.5.602","article-title":"Ventricular vulnerability during sympathetic stimulation: role of heart rate and blood pressure","volume":"8","author":"Verrier","year":"1974","journal-title":"Cardiovasc Res"},{"key":"2019052205004238900_cvz053-B36","first-page":"F72","article-title":"The autonomic nervous system and sudden death","volume":"19 Suppl F","author":"Schwartz","year":"1998","journal-title":"Eur Heart J"},{"key":"2019052205004238900_cvz053-B37","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1161\/01.RES.68.5.1471","article-title":"Vagal stimulation and prevention of sudden death in conscious dogs with a healed myocardial infarction","volume":"68","author":"Vanoli","year":"1991","journal-title":"Circ Res"},{"key":"2019052205004238900_cvz053-B38","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1113\/expphysiol.2013.072652","article-title":"Vagal modulation of cardiac ventricular arrhythmia","volume":"99","author":"Ng","year":"2014","journal-title":"Exp Physiol"},{"key":"2019052205004238900_cvz053-B39","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1161\/01.RES.14.1.44","article-title":"Nonuniform recovery of excitability in ventricular muscle","volume":"14","author":"Han","year":"1964","journal-title":"Circ Res"},{"key":"2019052205004238900_cvz053-B40","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1093\/cvr\/27.11.1954","article-title":"Dispersion of refractoriness in normal and ischaemic canine ventricle: effects of sympathetic stimulation","volume":"27","author":"Opthof","year":"1993","journal-title":"Cardiovasc Res"},{"key":"2019052205004238900_cvz053-B41","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1113\/eph8602146","article-title":"Effects of direct sympathetic and vagus nerve stimulation on the physiology of the whole heart\u2014a novel model of isolated Langendorff perfused rabbit heart with intact dual autonomic innervation","volume":"86","author":"Ng","year":"2001","journal-title":"Exp Physiol"},{"key":"2019052205004238900_cvz053-B42","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.cardiores.2006.12.001","article-title":"Autonomic modulation of electrical restitution, alternans and ventricular fibrillation initiation in the isolated heart","volume":"73","author":"Ng","year":"2007","journal-title":"Cardiovasc Res"},{"key":"2019052205004238900_cvz053-B43","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1113\/jphysiol.2007.138461","article-title":"Nitric oxide mediates the vagal protective effect on ventricular fibrillation via effects on action potential duration restitution in the rabbit heart","volume":"583","author":"Brack","year":"2007","journal-title":"J Physiol"},{"key":"2019052205004238900_cvz053-B44","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1093\/cvr\/cvr105","article-title":"Vagus nerve stimulation protects against ventricular fibrillation independent of muscarinic receptor activation","volume":"91","author":"Brack","year":"2011","journal-title":"Cardiovasc Res"},{"key":"2019052205004238900_cvz053-B45","doi-asserted-by":"crossref","first-page":"4044","DOI":"10.1161\/01.CIR.96.11.4044","article-title":"Intrapericardial delivery of L-arginine reduces the increased severity of ventricular arrhythmias during sympathetic stimulation in dogs with acute coronary occlusion: nitric oxide modulates sympathetic effects on ventricular electrophysiological properties","volume":"96","author":"Fei","year":"1997","journal-title":"Circulation"},{"key":"2019052205004238900_cvz053-B46","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1016\/j.jcin.2017.04.036","article-title":"Low-level tragus stimulation for the treatment of ischemia and reperfusion injury in patients with ST-segment elevation myocardial infarction: a proof-of-concept study","volume":"10","author":"Yu","year":"2017","journal-title":"JACC Cardiovasc Interv"},{"key":"2019052205004238900_cvz053-B47","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1016\/0735-1097(89)90391-4","article-title":"Regional sympathetic denervation after myocardial infarction in humans detected noninvasively using I-123-metaiodobenzylguanidine","volume":"14","author":"Stanton","year":"1989","journal-title":"J Am Coll Cardiol"},{"key":"2019052205004238900_cvz053-B48","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1161\/01.CIR.101.16.1960","article-title":"Relationship between regional cardiac hyperinnervation and ventricular arrhythmia","volume":"101","author":"Cao","year":"2000","journal-title":"Circulation"},{"key":"2019052205004238900_cvz053-B49","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.hrthm.2015.01.045","article-title":"Remodeling of stellate ganglion neurons after spatially targeted myocardial infarction: neuropeptide and morphologic changes","volume":"12","author":"Ajijola","year":"2015","journal-title":"Heart Rhythm"},{"key":"2019052205004238900_cvz053-B50","doi-asserted-by":"crossref","first-page":"e004172.","DOI":"10.1161\/CIRCINTERVENTIONS.116.004172","article-title":"Effects of renal artery denervation on ventricular arrhythmias in a postinfarct model","volume":"10","author":"Jackson","year":"2017","journal-title":"Circ Cardiovasc Interv"},{"key":"2019052205004238900_cvz053-B51","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1159\/000489653","article-title":"Renal denervation effects on myocardial fibrosis and ventricular arrhythmias in rats with ischemic cardiomyopathy","volume":"46","author":"Zhang","year":"2018","journal-title":"Cell Physiol Biochem"},{"key":"2019052205004238900_cvz053-B52","doi-asserted-by":"crossref","first-page":"3070","DOI":"10.1016\/j.jacc.2017.04.035","article-title":"Cardiac sympathetic denervation for refractory ventricular arrhythmias","volume":"69","author":"Vaseghi","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2019052205004238900_cvz053-B53","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ijcard.2018.03.119","article-title":"Functional selectivity of cardiac preganglionic sympathetic neurones in the rabbit heart","volume":"264","author":"Chauhan","year":"2018","journal-title":"Int J Cardiol"},{"key":"2019052205004238900_cvz053-B54","doi-asserted-by":"crossref","first-page":"2715.","DOI":"10.1113\/jphysiol.2009.174466","article-title":"Cardiac defibrillator neurones","volume":"587","author":"Jones","year":"2009","journal-title":"J Physiol (Lond)"},{"key":"2019052205004238900_cvz053-B55","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.autneu.2016.07.001","article-title":"Neuro-cardiac interaction in malignant ventricular arrhythmia and sudden cardiac death","volume":"199","author":"Ng","year":"2016","journal-title":"Auton Neurosci"},{"key":"2019052205004238900_cvz053-B56","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1038\/sj.bjp.0707673","article-title":"Heart rate in the pathophysiology of coronary blood flow and myocardial ischaemia: benefit from selective bradycardic agents","volume":"153","author":"Heusch","year":"2008","journal-title":"Br J Pharmacol"},{"key":"2019052205004238900_cvz053-B57","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1097\/00005344-198409000-00034","article-title":"adrenoceptor-mediated vasoconstriction of large and small canine coronary arteries in vivo","volume":"6","author":"Heusch","year":"1984","journal-title":"J Cardiovasc Pharmacol"},{"key":"2019052205004238900_cvz053-B58","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1161\/01.RES.53.1.8","article-title":"The effects of cardiac sympathetic nerve stimulation on perfusion of stenotic coronary arteries in the dog","volume":"53","author":"Heusch","year":"1983","journal-title":"Circ Res"},{"key":"2019052205004238900_cvz053-B59","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1161\/01.RES.62.3.436","article-title":"Intracoronary alpha 2-adrenergic receptor blockade attenuates ischemia in conscious dogs during exercise","volume":"62","author":"Seitelberger","year":"1988","journal-title":"Circ Res"},{"key":"2019052205004238900_cvz053-B60","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1161\/01.RES.59.2.133","article-title":"Absence of functioning alpha-adrenergic receptors in mature canine coronary collaterals","volume":"59","author":"Harrison","year":"1986","journal-title":"Circ Res"},{"key":"2019052205004238900_cvz053-B61","first-page":"H525","article-title":"Responses to coronary artery occlusion in conscious dogs with selective cardiac denervation","volume":"255","author":"Shen","year":"1988","journal-title":"Am J Physiol"},{"key":"2019052205004238900_cvz053-B62","first-page":"H1322","article-title":"Chronic whole body sympathectomy fails to protect ischemic rabbit hearts","volume":"256","author":"Matsuki","year":"1989","journal-title":"Am J Physiol"},{"key":"2019052205004238900_cvz053-B63","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/S1053-0770(97)90257-3","article-title":"High spinal anesthesia does not alter experimental myocardial infarction size or ischemic preconditioning","volume":"11","author":"Haessler","year":"1997","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"2019052205004238900_cvz053-B64","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1093\/cvr\/cvx227","article-title":"Local sympathetic denervation attenuates myocardial inflammation and improves cardiac function after myocardial infarction in mice","volume":"114","author":"Ziegler","year":"2018","journal-title":"Cardiovasc Res"},{"key":"2019052205004238900_cvz053-B65","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.ijcard.2006.03.017","article-title":"Carvedilol preserves endothelial junctions and reduces myocardial no-reflow after acute myocardial infarction and reperfusion","volume":"115","author":"Zhao","year":"2007","journal-title":"Int J Cardiol"},{"key":"2019052205004238900_cvz053-B66","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1161\/01.CIR.101.6.689","article-title":"alpha-adrenergic coronary vasoconstriction and myocardial ischemia in humans","volume":"101","author":"Heusch","year":"2000","journal-title":"Circulation"},{"key":"2019052205004238900_cvz053-B67","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1161\/01.CIR.99.4.482","article-title":"Alpha-adrenergic blockade improves recovery of myocardial perfusion and function after coronary stenting in patients with acute myocardial infarction","volume":"99","author":"Gregorini","year":"1999","journal-title":"Circulation"},{"key":"2019052205004238900_cvz053-B68","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1016\/j.jcin.2017.05.063","article-title":"Vagal cardioprotection in reperfused acute myocardial infarction","volume":"10","author":"Heusch","year":"2017","journal-title":"JACC Cardiovasc Interv"},{"key":"2019052205004238900_cvz053-B69","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.ijcard.2016.10.074","article-title":"Intravenous electrical vagal nerve stimulation prior to coronary reperfusion in a canine ischemia-reperfusion model markedly reduces infarct size and prevents subsequent heart failure","volume":"227","author":"Arimura","year":"2017","journal-title":"Int J Cardiol"},{"key":"2019052205004238900_cvz053-B70","doi-asserted-by":"crossref","first-page":"508.","DOI":"10.1007\/s00395-015-0508-3","article-title":"Vagal nerve stimulation started just prior to reperfusion limits infarct size and no-reflow","volume":"110","author":"Uitterdijk","year":"2015","journal-title":"Basic Res Cardiol"},{"key":"2019052205004238900_cvz053-B71","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/nature06685","article-title":"Haematopoietic stem cell release is regulated by circadian oscillations","volume":"452","author":"Mendez-Ferrer","year":"2008","journal-title":"Nature"},{"key":"2019052205004238900_cvz053-B72","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.cell.2015.12.023","article-title":"Neuro-immune interactions drive tissue programming in intestinal macrophages","volume":"164","author":"Gabanyi","year":"2016","journal-title":"Cell"},{"key":"2019052205004238900_cvz053-B73","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.bbi.2007.03.008","article-title":"Autonomic innervation and regulation of the immune system (1987-2007)","volume":"21","author":"Nance","year":"2007","journal-title":"Brain Behav Immun"},{"key":"2019052205004238900_cvz053-B74","doi-asserted-by":"crossref","first-page":"680","DOI":"10.4049\/jimmunol.165.2.680","article-title":"Stimulation of the B cell receptor, CD86 (B7-2), and the beta 2-adrenergic receptor intrinsically modulates the level of IgG1 and IgE produced per B cell","volume":"165","author":"Kasprowicz","year":"2000","journal-title":"J Immunol"},{"key":"2019052205004238900_cvz053-B75","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1161\/HYPERTENSIONAHA.111.186833","article-title":"Autonomic neural regulation of the immune system: implications for hypertension and cardiovascular disease","volume":"59","author":"Abboud","year":"2012","journal-title":"Hypertension"},{"key":"2019052205004238900_cvz053-B76","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.2174\/0929867324666170329100619","article-title":"The role of redox dysregulation in the inflammatory response to acute myocardial ischaemia-reperfusion injury\u2014adding fuel to the fire","volume":"25","author":"Hernandez-Resendiz","year":"2018","journal-title":"Curr Med Chem"},{"key":"2019052205004238900_cvz053-B77","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.pharmthera.2018.01.001","article-title":"Inflammation following acute myocardial infarction: multiple players, dynamic roles, and novel therapeutic opportunities","volume":"186","author":"Ong","year":"2018","journal-title":"Pharmacol Ther"},{"key":"2019052205004238900_cvz053-B78","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1007\/s00395-009-0033-3","article-title":"Macrophage depletion suppresses sympathetic hyperinnervation following myocardial infarction","volume":"104","author":"Wernli","year":"2009","journal-title":"Basic Res Cardiol"},{"key":"2019052205004238900_cvz053-B79","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1161\/01.CIR.74.5.1124","article-title":"Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium","volume":"74","author":"Murry","year":"1986","journal-title":"Circulation"},{"key":"2019052205004238900_cvz053-B80","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.yjmcc.2018.10.013","article-title":"The non-neuronal cholinergic system in the heart: a comprehensive review","volume":"125","author":"Saw","year":"2018","journal-title":"J Mol Cell Cardiol"},{"key":"2019052205004238900_cvz053-B81","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1161\/hh1501.094266","article-title":"Acetylcholine, bradykinin, opioids, and phenylephrine, but not adenosine, trigger preconditioning by generating free radicals and opening mitochondrial K(ATP) channels","volume":"89","author":"Cohen","year":"2001","journal-title":"Circ Res"},{"key":"2019052205004238900_cvz053-B82","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.lfs.2009.08.015","article-title":"Detection of endogenous acetylcholine release during brief ischemia in the rabbit ventricle: a possible trigger for ischemic preconditioning","volume":"85","author":"Kawada","year":"2009","journal-title":"Life Sci"},{"key":"2019052205004238900_cvz053-B83","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1006\/jmcc.1999.1087","article-title":"Differential acetylcholine release mechanisms in the ischemic and non-ischemic myocardium","volume":"32","author":"Kawada","year":"2000","journal-title":"J Mol Cell Cardiol"},{"key":"2019052205004238900_cvz053-B84","doi-asserted-by":"crossref","first-page":"11.","DOI":"10.1007\/s00395-017-0601-x","article-title":"Intrinsic cardiac ganglia and acetylcholine are important in the mechanism of ischaemic preconditioning","volume":"112","author":"Pickard","year":"2017","journal-title":"Basic Res Cardiol"},{"key":"2019052205004238900_cvz053-B85","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1161\/01.RES.0000251282.79411.44","article-title":"Obligatory role of cardiac nerves and alpha1-adrenergic receptors for the second window of ischemic preconditioning in conscious pigs","volume":"99","author":"Kudej","year":"2006","journal-title":"Circ Res"},{"key":"2019052205004238900_cvz053-B86","doi-asserted-by":"crossref","first-page":"1532.","DOI":"10.1111\/j.1476-5381.1995.tb16647.x","article-title":"Myocardial and coronary endothelial protective effects of acetylcholine after myocardial ischaemia and reperfusion in rats: role of nitric oxide","volume":"115","author":"Richard","year":"1995","journal-title":"Br J Pharmacol"},{"key":"2019052205004238900_cvz053-B87","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1113\/expphysiol.2012.064923","article-title":"Remote ischaemic pre- and delayed postconditioning\u2014similar degree of cardioprotection but distinct mechanisms","volume":"97","author":"Basalay","year":"2012","journal-title":"Exp Physiol"},{"key":"2019052205004238900_cvz053-B88","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1161\/01.CIR.87.3.893","article-title":"Regional ischemic \u2018preconditioning\u2019 protects remote virgin myocardium from subsequent sustained coronary occlusion","volume":"87","author":"Przyklenk","year":"1993","journal-title":"Circulation"},{"key":"2019052205004238900_cvz053-B89","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1093\/cvr\/cvn114","article-title":"Remote ischaemic preconditioning: underlying mechanisms and clinical application","volume":"79","author":"Hausenloy","year":"2008","journal-title":"Cardiovasc Res"},{"key":"2019052205004238900_cvz053-B90","doi-asserted-by":"crossref","first-page":"453.","DOI":"10.1007\/s00395-014-0453-6","article-title":"Remote ischemic conditioning: from experimental observation to clinical application: report from the 8th Biennial Hatter Cardiovascular Institute Workshop","volume":"110","author":"Pickard","year":"2015","journal-title":"Basic Res Cardiol"},{"key":"2019052205004238900_cvz053-B91","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1111\/anae.12973","article-title":"Remote ischaemic conditioning: cardiac protection from afar","volume":"70","author":"Sivaraman","year":"2015","journal-title":"Anaesthesia"},{"key":"2019052205004238900_cvz053-B92","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.jacc.2014.10.031","article-title":"Remote ischemic conditioning","volume":"65","author":"Heusch","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"2019052205004238900_cvz053-B93","doi-asserted-by":"crossref","first-page":"15.","DOI":"10.1007\/s00395-018-0673-2","article-title":"25 years of remote ischemic conditioning: from laboratory curiosity to clinical outcome","volume":"113","author":"Heusch","year":"2018","journal-title":"Basic Res Cardiol"},{"key":"2019052205004238900_cvz053-B94","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s00424-016-1922-6","article-title":"Cardioprotection by remote ischemic conditioning and its signal transduction","volume":"469","author":"Kleinbongard","year":"2017","journal-title":"Pflugers Arch"},{"key":"2019052205004238900_cvz053-B95","doi-asserted-by":"crossref","first-page":"25.","DOI":"10.1007\/s00395-018-0684-z","article-title":"Neural mechanisms in remote ischaemic conditioning in the heart and brain: mechanistic and translational aspects","volume":"113","author":"Basalay","year":"2018","journal-title":"Basic Res Cardiol"},{"key":"2019052205004238900_cvz053-B96","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1161\/01.CIR.94.9.2193","article-title":"Myocardial protection by brief ischemia in noncardiac tissue","volume":"94","author":"Gho","year":"1996","journal-title":"Circulation"},{"key":"2019052205004238900_cvz053-B97","first-page":"41","article-title":"Limb ischemic preconditioning reduces infarct size following myocardial ischemia-reperfusion in rats","volume":"56","author":"Dong","year":"2004","journal-title":"Sheng Li Xue Bao"},{"key":"2019052205004238900_cvz053-B98","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1007\/s00395-010-0099-y","article-title":"The neural and humoral pathways in remote limb ischemic preconditioning","volume":"105","author":"Lim","year":"2010","journal-title":"Basic Res Cardiol"},{"key":"2019052205004238900_cvz053-B99","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1042\/CS20080523","article-title":"Transient limb ischaemia remotely preconditions through a humoral mechanism acting directly on the myocardium: evidence suggesting cross-species protection","volume":"117","author":"Shimizu","year":"2009","journal-title":"Clin Sci"},{"key":"2019052205004238900_cvz053-B100","doi-asserted-by":"crossref","first-page":"50.","DOI":"10.1007\/s00395-016-0568-z","article-title":"Co-dependence of the neural and humoral pathways in the mechanism of remote ischemic conditioning","volume":"111","author":"Pickard","year":"2016","journal-title":"Basic Res Cardiol"},{"key":"2019052205004238900_cvz053-B101","doi-asserted-by":"crossref","first-page":"H1598","DOI":"10.1152\/ajpheart.00396.2010","article-title":"Pretreatment with the nitric oxide donor SNAP or nerve transection blocks humoral preconditioning by remote limb ischemia or intra-arterial adenosine","volume":"299","author":"Steensrud","year":"2010","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2019052205004238900_cvz053-B102","doi-asserted-by":"crossref","first-page":"39.","DOI":"10.1007\/s00395-018-0696-8","article-title":"Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection","volume":"113","author":"Botker","year":"2018","journal-title":"Basic Res Cardiol"},{"key":"2019052205004238900_cvz053-B103","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00395-011-0241-5","article-title":"Remote cardioprotection by direct peripheral nerve stimulation and topical capsaicin is mediated by circulating humoral factors","volume":"107","author":"Redington","year":"2012","journal-title":"Basic Res Cardiol"},{"key":"2019052205004238900_cvz053-B104","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0014-2999(96)00426-8","article-title":"Calcitonin gene-related peptide-induced preconditioning protects against ischemia-reperfusion injury in isolated rat hearts","volume":"311","author":"Li","year":"1996","journal-title":"Eur J Pharmacol"},{"key":"2019052205004238900_cvz053-B105","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1161\/CIRCULATIONAHA.108.843938","article-title":"Peripheral nociception associated with surgical incision elicits remote nonischemic cardioprotection via neurogenic activation of protein kinase C signaling","volume":"120","author":"Jones","year":"2009","journal-title":"Circulation"},{"key":"2019052205004238900_cvz053-B106","doi-asserted-by":"crossref","first-page":"406.","DOI":"10.1007\/s00395-014-0406-0","article-title":"Transcutaneous electrical nerve stimulation as a novel method of remote preconditioning: in vitro validation in an animal model and first human observations","volume":"109","author":"Merlocco","year":"2014","journal-title":"Basic Res Cardiol"},{"key":"2019052205004238900_cvz053-B107","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s12576-013-0259-6","article-title":"Electroacupuncture reduces myocardial infarct size and improves post-ischemic recovery by invoking release of humoral, dialyzable, cardioprotective factors","volume":"63","author":"Redington","year":"2013","journal-title":"J Physiol Sci"},{"key":"2019052205004238900_cvz053-B108","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/j.athoracsur.2009.12.003","article-title":"Cardioprotective effects of electroacupuncture pretreatment on patients undergoing heart valve replacement surgery: a randomized controlled trial","volume":"89","author":"Yang","year":"2010","journal-title":"Ann Thorac Surg"},{"key":"2019052205004238900_cvz053-B109","first-page":"6243630.","article-title":"Cardioprotection of electroacupuncture for enhanced recovery after surgery on patients undergoing heart valve replacement with cardiopulmonary bypass: a randomized control clinical trial","volume":"2017","author":"Zhang","year":"2017","journal-title":"Evid Based Complement Alternat Med"},{"key":"2019052205004238900_cvz053-B110","doi-asserted-by":"crossref","first-page":"285.","DOI":"10.1007\/s00395-012-0285-1","article-title":"Release of a humoral circulating cardioprotective factor by remote ischemic preconditioning is dependent on preserved neural pathways in diabetic patients","volume":"107","author":"Jensen","year":"2012","journal-title":"Basic Res Cardiol"},{"key":"2019052205004238900_cvz053-B111","doi-asserted-by":"crossref","first-page":"381.","DOI":"10.1007\/s00395-013-0381-x","article-title":"Nociceptive-induced myocardial remote conditioning is mediated by neuronal gamma protein kinase C","volume":"108","author":"Gross","year":"2013","journal-title":"Basic Res Cardiol"},{"key":"2019052205004238900_cvz053-B112","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s10557-016-6661-6","article-title":"Remote postconditioning induced by trauma protects the mouse heart against ischemia reperfusion injury. Involvement of the neural pathway and molecular mechanisms","volume":"30","author":"Song","year":"2016","journal-title":"Cardiovasc Drugs Ther"},{"key":"2019052205004238900_cvz053-B113","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.lfs.2012.08.037","article-title":"Cardioprotection from remote preconditioning involves spinal opioid receptor activation","volume":"91","author":"Wong","year":"2012","journal-title":"Life Sci"},{"key":"2019052205004238900_cvz053-B114","doi-asserted-by":"crossref","first-page":"H311","DOI":"10.1152\/ajpheart.00087.2006","article-title":"Preemptive, but not reactive, spinal cord stimulation mitigates transient ischemia-induced myocardial infarction via cardiac adrenergic neurons","volume":"292","author":"Southerland","year":"2007","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2019052205004238900_cvz053-B115","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1213\/01.ANE.0000105878.96434.05","article-title":"Intrathecal morphine reduces infarct size in a rat model of ischemia-reperfusion injury","volume":"98","author":"Groban","year":"2004","journal-title":"Anesth Analg"},{"key":"2019052205004238900_cvz053-B116","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jss.2014.08.014","article-title":"Remote intrathecal morphine preconditioning confers cardioprotection via spinal cord nitric oxide\/cyclic guanosine monophosphate\/protein kinase G pathway","volume":"193","author":"Lu","year":"2015","journal-title":"J Surg Res"},{"key":"2019052205004238900_cvz053-B117","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1124\/jpet.116.234021","article-title":"Spinal neuronal NOS signaling contributes to morphine cardioprotection in ischemia reperfusion injury in rats","volume":"358","author":"Jiang","year":"2016","journal-title":"J Pharmacol Exp Ther"},{"key":"2019052205004238900_cvz053-B118","doi-asserted-by":"crossref","first-page":"H1571","DOI":"10.1152\/ajpheart.2000.278.5.H1571","article-title":"Bradykinin mediates cardiac preconditioning at a distance","volume":"278","author":"Schoemaker","year":"2000","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2019052205004238900_cvz053-B119","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/S0008-6363(02)00446-7","article-title":"Remote preconditioning by infrarenal occlusion of the aorta protects the heart from infarction: a newly identified non-neuronal but PKC-dependent pathway","volume":"55","author":"Weinbrenner","year":"2002","journal-title":"Cardiovasc Res"},{"key":"2019052205004238900_cvz053-B120","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.jacc.2005.04.044","article-title":"Remote ischemic preconditioning provides early and late protection against endothelial ischemia-reperfusion injury in humans: role of the autonomic nervous system","volume":"46","author":"Loukogeorgakis","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"2019052205004238900_cvz053-B121","doi-asserted-by":"crossref","first-page":"H1289","DOI":"10.1152\/ajpheart.00286.2017","article-title":"Vagal stimulation mimics preconditioning and postconditioning of ischemic myocardium in mice by activating different protection mechanisms","volume":"314","author":"Buchholz","year":"2018","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2019052205004238900_cvz053-B122","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1113\/expphysiol.2012.066217","article-title":"Role of the parasympathetic nervous system in cardioprotection by remote hindlimb ischaemic preconditioning","volume":"98","author":"Donato","year":"2013","journal-title":"Exp Physiol"},{"key":"2019052205004238900_cvz053-B123","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1093\/cvr\/cvs212","article-title":"Cardioprotection evoked by remote ischaemic preconditioning is critically dependent on the activity of vagal pre-ganglionic neurones","volume":"95","author":"Mastitskaya","year":"2012","journal-title":"Cardiovasc Res"},{"key":"2019052205004238900_cvz053-B124","doi-asserted-by":"crossref","first-page":"e0150108.","DOI":"10.1371\/journal.pone.0150108","article-title":"Identifying the source of a humoral factor of remote (pre)conditioning cardioprotection","volume":"11","author":"Mastitskaya","year":"2016","journal-title":"PLoS One"},{"key":"2019052205004238900_cvz053-B125","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1093\/cvr\/cvw216","article-title":"Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning","volume":"112","author":"Basalay","year":"2016","journal-title":"Cardiovasc Res"},{"key":"2019052205004238900_cvz053-B126","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.jacc.2008.10.033","article-title":"Exenatide reduces infarct size and improves cardiac function in a porcine model of ischemia and reperfusion injury","volume":"53","author":"Timmers","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"2019052205004238900_cvz053-B127","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1093\/eurheartj\/ehr309","article-title":"Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction","volume":"33","author":"Lonborg","year":"2012","journal-title":"Eur Heart J"},{"key":"2019052205004238900_cvz053-B128","doi-asserted-by":"crossref","first-page":"e23570.","DOI":"10.1371\/journal.pone.0023570","article-title":"Albiglutide, a long lasting glucagon-like peptide-1 analog, protects the rat heart against ischemia\/reperfusion injury: evidence for improving cardiac metabolic efficiency","volume":"6","author":"Bao","year":"2011","journal-title":"PLoS One"},{"key":"2019052205004238900_cvz053-B129","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1093\/cvr\/cvv171","article-title":"Combination therapy with remote ischaemic conditioning and insulin or exenatide enhances infarct size limitation in pigs","volume":"107","author":"Alburquerque-B\u00e9jar","year":"2015","journal-title":"Cardiovasc Res"},{"key":"2019052205004238900_cvz053-B130","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1161\/CIRCRESAHA.118.313859","article-title":"Vago-splenic axis in signal transduction of remote ischemic preconditioning in pigs and rats","volume":"123","author":"Lieder","year":"2018","journal-title":"Circ Res"},{"key":"2019052205004238900_cvz053-B131","doi-asserted-by":"crossref","first-page":"167.","DOI":"10.1186\/s12974-018-1190-9","article-title":"Splenic responses play an important role in remote ischemic preconditioning-mediated neuroprotection against stroke","volume":"15","author":"Chen","year":"2018","journal-title":"J Neuroinflammation"},{"key":"2019052205004238900_cvz053-B132","doi-asserted-by":"crossref","first-page":"826.","DOI":"10.1038\/s41467-017-00891-z","article-title":"Cardioprotection induced in a mouse model of neuropathic pain via anterior nucleus of paraventricular thalamus","volume":"8","author":"Cheng","year":"2017","journal-title":"Nat Commun"},{"key":"2019052205004238900_cvz053-B133","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/0002-8703(78)90504-5","article-title":"The effect of chronic cardiac denervation on infarct size following acute coronary occlusion","volume":"95","author":"Jones","year":"1978","journal-title":"Am Heart J"},{"key":"2019052205004238900_cvz053-B134","first-page":"H429","article-title":"Effects of coronary ligation of the chromically sympathectomized dog ventricle","volume":"235","author":"Jones","year":"1978","journal-title":"Am J Physiol"},{"key":"2019052205004238900_cvz053-B135","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1177\/1074248416687874","article-title":"Remote ischemic conditioning in cardiovascular surgery","volume":"22","author":"Heusch","year":"2017","journal-title":"J Cardiovasc Pharmacol Ther"},{"key":"2019052205004238900_cvz053-B136","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.neuropharm.2007.11.001","article-title":"Propofol enhances both tonic and phasic inhibitory currents in second-order neurons of the solitary tract nucleus (NTS)","volume":"54","author":"McDougall","year":"2008","journal-title":"Neuropharmacology"},{"key":"2019052205004238900_cvz053-B137","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1097\/00000542-200405000-00023","article-title":"Propofol modulates gamma-aminobutyric acid-mediated inhibitory neurotransmission to cardiac vagal neurons in the nucleus ambiguus","volume":"100","author":"Wang","year":"2004","journal-title":"Anesthesiology"},{"key":"2019052205004238900_cvz053-B138","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1213\/ANE.0000000000002563","article-title":"Impact of anesthetic regimen on remote ischemic preconditioning in the rat heart in vivo","volume":"126","author":"Behmenburg","year":"2018","journal-title":"Anesth Analg"},{"key":"2019052205004238900_cvz053-B139","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1399-6576.2011.02585.x","article-title":"Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol\u2014a clinical trial","volume":"56","author":"Kottenberg","year":"2012","journal-title":"Acta Anaesthesiol Scand"},{"key":"2019052205004238900_cvz053-B140","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.jtcvs.2013.01.005","article-title":"Interference of propofol with signal transducer and activator of transcription 5 activation and cardioprotection by remote ischemic preconditioning during coronary artery bypass grafting","volume":"147","author":"Kottenberg","year":"2014","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2019052205004238900_cvz053-B141","doi-asserted-by":"crossref","first-page":"e0134264.","DOI":"10.1371\/journal.pone.0134264","article-title":"Additive effect on survival of anaesthetic cardiac protection and remote ischemic preconditioning in cardiac surgery: a Bayesian network meta-analysis of randomized trials","volume":"10","author":"Zangrillo","year":"2015","journal-title":"PLoS One"},{"key":"2019052205004238900_cvz053-B142","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1056\/NEJMoa1413534","article-title":"Remote ischemic preconditioning and outcomes of cardiac surgery","volume":"373","author":"Hausenloy","year":"2015","journal-title":"N Engl J Med"},{"key":"2019052205004238900_cvz053-B143","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1056\/NEJMoa1413579","article-title":"A multicenter trial of remote ischemic preconditioning for heart surgery","volume":"373","author":"Meybohm","year":"2015","journal-title":"N Engl J Med"},{"key":"2019052205004238900_cvz053-B144","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1093\/eurheartj\/ehv606","article-title":"ERICCA and RIPHeart: two nails in the coffin for cardioprotection by remote ischemic conditioning? Probably not!","volume":"37","author":"Heusch","year":"2016","journal-title":"Eur Heart J"},{"key":"2019052205004238900_cvz053-B145","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/S0008-6363(95)00217-0","article-title":"The evolution of diabetic response to ischemia\/reperfusion and preconditioning in isolated working rat hearts","volume":"31","author":"Tosaki","year":"1996","journal-title":"Cardiovasc Res"},{"key":"2019052205004238900_cvz053-B146","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/S0008-6363(97)00234-4","article-title":"Protection afforded by preconditioning to the diabetic heart against ischaemic injury","volume":"37","author":"Bouchard","year":"1998","journal-title":"Cardiovasc Res"},{"key":"2019052205004238900_cvz053-B147","doi-asserted-by":"crossref","first-page":"H1218","DOI":"10.1152\/ajpheart.2000.278.4.H1218","article-title":"Diabetes abolishes ischemic preconditioning: role of glucose, insulin, and osmolality","volume":"278","author":"Kersten","year":"2000","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2019052205004238900_cvz053-B148","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1007\/s00125-004-1514-4","article-title":"Ischaemic preconditioning does not protect the heart in obese and lean animal models of type 2 diabetes","volume":"47","author":"Kristiansen","year":"2004","journal-title":"Diabetologia"},{"key":"2019052205004238900_cvz053-B149","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.2337\/diabetes.54.8.2360","article-title":"Preconditioning the diabetic heart: the importance of AKT phosphorylation","volume":"54","author":"Tsang","year":"2005","journal-title":"Diabetes"},{"key":"2019052205004238900_cvz053-B150","doi-asserted-by":"crossref","first-page":"845698.","DOI":"10.1155\/2012\/845698","article-title":"The diabetic heart: too sweet for its own good?","volume":"2012","author":"Whittington","year":"2012","journal-title":"Cardiol Res Pract"},{"key":"2019052205004238900_cvz053-B151","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1111\/j.1582-4934.2009.00796.x","article-title":"Preconditioning the diabetic human myocardium","volume":"14","author":"Sivaraman","year":"2010","journal-title":"J Cell Mol Med"},{"key":"2019052205004238900_cvz053-B152","doi-asserted-by":"crossref","first-page":"e006923.","DOI":"10.1136\/bmjopen-2014-006923","article-title":"Impact of cardiovascular risk factors and medication use on the efficacy of remote ischaemic conditioning: post hoc subgroup analysis of a randomised controlled trial","volume":"5","author":"Sloth","year":"2015","journal-title":"BMJ Open"},{"key":"2019052205004238900_cvz053-B153","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/aas.12278","article-title":"Myocardial protection by remote ischaemic pre-conditioning is abolished in sulphonylurea-treated diabetics undergoing coronary revascularisation","volume":"58","author":"Kottenberg","year":"2014","journal-title":"Acta Anaesthesiol Scand"},{"key":"2019052205004238900_cvz053-B154","doi-asserted-by":"crossref","first-page":"e0192981.","DOI":"10.1371\/journal.pone.0192981","article-title":"Influence of diabetes mellitus duration on the efficacy of ischemic preconditioning in a Zucker diabetic fatty rat model","volume":"13","author":"Hjortbak","year":"2018","journal-title":"PLoS One"},{"key":"2019052205004238900_cvz053-B155","doi-asserted-by":"crossref","first-page":"e64093.","DOI":"10.1371\/journal.pone.0064093","article-title":"Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation","volume":"8","author":"Povlsen","year":"2013","journal-title":"PLoS One"},{"key":"2019052205004238900_cvz053-B156","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1046\/j.1365-2362.2000.00631.x","article-title":"Ultrastructural changes of human cardiac atrial nerve endings in diabetes mellitus","volume":"30","author":"Schramm","year":"2000","journal-title":"Eur J Clin Invest"},{"key":"2019052205004238900_cvz053-B157","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1679\/aohc.54.41","article-title":"The cardiac ganglia in streptozotocin-induced diabetic rats","volume":"54","author":"Kamal","year":"1991","journal-title":"Arch Histol Cytol"},{"key":"2019052205004238900_cvz053-B158","doi-asserted-by":"crossref","first-page":"85.","DOI":"10.1186\/1475-2840-12-85","article-title":"Remodelling of the intracardiac ganglia in diabetic Goto-Kakizaki rats: an anatomical study","volume":"12","author":"Batulevicius","year":"2013","journal-title":"Cardiovasc Diabetol"},{"key":"2019052205004238900_cvz053-B159","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.autneu.2011.01.008","article-title":"Remodeling of cardiac cholinergic innervation and control of heart rate in mice with streptozotocin-induced diabetes","volume":"162","author":"Mabe","year":"2011","journal-title":"Auton Neurosci"},{"key":"2019052205004238900_cvz053-B160","first-page":"935","article-title":"Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations","volume":"38","author":"Hausenloy","year":"2017","journal-title":"Eur Heart J"},{"key":"2019052205004238900_cvz053-B161","first-page":"1846","article-title":"Effect of remote ischaemic conditioning on clinical outcomes in patients presenting with an ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention","volume":"36","author":"Hausenloy","year":"2015","journal-title":"Eur Heart J"}],"container-title":["Cardiovascular Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cardiovascres\/article-pdf\/115\/7\/1167\/28679750\/cvz053.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T07:32:22Z","timestamp":1558510342000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cardiovascres\/article\/115\/7\/1167\/5364019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,23]]},"references-count":161,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2019,2,23]]},"published-print":{"date-parts":[[2019,6,1]]}},"URL":"https:\/\/doi.org\/10.1093\/cvr\/cvz053","relation":{},"ISSN":["0008-6363","1755-3245"],"issn-type":[{"value":"0008-6363","type":"print"},{"value":"1755-3245","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,6,1]]},"published":{"date-parts":[[2019,2,23]]}}}