{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T18:31:02Z","timestamp":1789497062026,"version":"build-2803163510"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T00:00:00Z","timestamp":1757462400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Intraoral ultrasonography (US) is known for its high accuracy in evaluating the depth of invasion (DOI) in tongue squamous cell carcinoma (SCC). However, measurement discrepancies, such as overestimation or underestimation, can occur in certain cases. This study aimed to identify factors affecting the measurement accuracy of intraoral US.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 96 cases were included in this study. Patients who underwent imaging diagnosis for primary tongue SCC by oral and maxillofacial radiologists, followed by surgical resection by oral surgeons at our institution between April 2014 and March 2022, were included in the study. Cases were classified according to their clinical and histopathological characteristics, including clinical growth pattern, maximum pathological tumour diameter, pathological T classification, and pattern of invasion (Yamamoto-Kohama classification). Measurement accuracy was evaluated using Spearman\u2019s rank correlation coefficient and Bland-Altman analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 76 cases were analysed. Intraoral US demonstrated high diagnostic accuracy across various tumour characteristics. However, greater DOI and larger maximum tumour diameter were associated with increased variability in measurements. Exophytic lesions were more likely to be overestimated, whereas lesions with diffuse infiltration tended to be underestimated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although intraoral US provides high accuracy in the preoperative evaluation of tongue SCC, clinicians should be aware of specific tumour characteristics that may influence measurement precision, leading to potential overestimation or underestimation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/dmfr\/twaf062","type":"journal-article","created":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T17:23:47Z","timestamp":1757525027000},"page":"80-87","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of factors affecting depth of invasion measurement in tongue squamous cell carcinoma using intraoral ultrasonography"],"prefix":"10.1093","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-0034-7771","authenticated-orcid":false,"given":"Masaki","family":"Takamura","sequence":"first","affiliation":[{"name":"Division of Oral and Maxillofacial Radiology, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University , Niigata 951-8514,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taichi","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Division of Oral and Maxillofacial Radiology, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University , Niigata 951-8514,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Nikkuni","sequence":"additional","affiliation":[{"name":"Division of Oral and Maxillofacial Radiology, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University , Niigata 951-8514,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7341-4840","authenticated-orcid":false,"given":"Kouji","family":"Katsura","sequence":"additional","affiliation":[{"name":"Division of Oral and Maxillofacial Radiology, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University , Niigata 951-8514,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manabu","family":"Yamazaki","sequence":"additional","affiliation":[{"name":"Division of Oral Pathology, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University , Niigata 951-8514,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-ichi","family":"Tanuma","sequence":"additional","affiliation":[{"name":"Division of Oral Pathology, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University , Niigata 951-8514,","place":["Japan"]},{"name":"Oral Pathology Section, Department of Surgical Pathology, Niigata University Medical & Dental Hospital , Niigata 951-8520,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takafumi","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Division of Oral and Maxillofacial Radiology, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University , Niigata 951-8514,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,9,10]]},"reference":[{"key":"2026011303220053900_twaf062-B1","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.oraloncology.2008.06.002","article-title":"Global epidemiology of oral and oropharyngeal cancer","volume":"45","author":"Warnakulasuriya","year":"2009","journal-title":"Oral Oncol"},{"key":"2026011303220053900_twaf062-B2","first-page":"79","volume-title":"AJCC Cancer Staging Manual","author":"Ridge","year":"2017","edition":"8th ed"},{"key":"2026011303220053900_twaf062-B3","doi-asserted-by":"publisher","first-page":"e163","DOI":"10.4317\/medoral.25983","article-title":"Has the 8th American joint committee on cancer TNM staging improved prognostic performance in oral cancer? 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