{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T02:29:30Z","timestamp":1791944970492,"version":"4.3.4"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Achalasia Quality of Life (ASQ) and Eckardt scores are two patient-reported instruments widely used to assess symptom severity in achalasia patients. ASQ is validated and reliable. Although Eckardt is commonly used, it has not been rigorously assessed for validity or reliability. This study aims to evaluate (i) the accuracy of Eckardt and ASQ for assessing improvement post-treatment (predictive validity), (ii) accuracy of Eckardt and ASQ for assessing improvement post-treatment with pneumatic dilatation (PD) versus surgical myotomy (predictive validity), and (iii) convergent validity of Eckardt and ASQ tools. Patients with achalasia treated between 2011 and 2018 were eligible. Both instruments were administered by telephone. Treatment failure was determined by the review of medical records by two clinicians. The predictive ability of ASQ and Eckardt instruments in identifying treatment successes and failures was determined using receiver operating characteristics analysis and summarized as area under the curve (AUC). A total of 106 patients met inclusion criteria with 39 PD, 51 Heller myotomy, and 16 per-oral endoscopic myotomy. A review of medical records and esophageal testing revealed 13 failures (12%). AUC for Eckardt was 0.96 (95% confidence interval [CI] 0.87\u20130.99] and ASQ 0.97 (95% CI 0.92\u20130.99). The Eckardt cutoff 4, and ASQ, cutoff\u00a015, were 94% and 87% accurate in identifying treatment successes versus failures, respectively. The correlation coefficient between the two tools was 0.85. In conclusions, (i) ASQ and Eckardt scores are valid and reliable tools to assess symptom severity in achalasia patients, (ii) both instruments accurately classify treatment successes versus failures, and (iii) the choice of tool should be informed by the physicians and patients\u2019 values and preferences and repeat physiologic testing may be reserved for treatment failures with either instrument and patients classified, as treatment successes may be spared routine physiologic testing in the long term.<\/jats:p>","DOI":"10.1093\/dote\/doaa080","type":"journal-article","created":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T06:22:23Z","timestamp":1599027743000},"source":"Crossref","is-referenced-by-count":48,"title":["Accuracy of Achalasia Quality of Life and Eckardt scores for assessment of clinical improvement post treatment for achalasia"],"prefix":"10.1093","volume":"34","author":[{"given":"Samuel","family":"Slone","sequence":"first","affiliation":[{"name":"Division of Digestive Diseases and Nutrition"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambuj","family":"Kumar","sequence":"additional","affiliation":[{"name":"Research Methodology and Biostatistics Core"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases and Nutrition"},{"name":"Joy McCann Culverhouse Center for Swallowing Disorders"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vic","family":"Velanovich","sequence":"additional","affiliation":[{"name":"Joy McCann Culverhouse Center for Swallowing Disorders"},{"name":"Division of General Surgery, Morsani College of Medicine University of South Florida, Tampa, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel E","family":"Richter","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases and Nutrition"},{"name":"Joy McCann Culverhouse Center for Swallowing Disorders"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,9,1]]},"reference":[{"issue":"9911","key":"2021021010564803200_ref1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0140-6736(13)60651-0","article-title":"Achalasia","volume":"383","author":"Boeckxstaens","year":"2014","journal-title":"The Lancet"},{"key":"2021021010564803200_ref2","first-page":"160","article-title":"The Chicago classification of esophageal motility disorders, v3.0","author":"Kahrilas","year":"2015"},{"issue":"2","key":"2021021010564803200_ref3","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1038\/ajg.2017.370","article-title":"Timed barium swallow: diagnostic role and predictive value in untreated achalasia, esophagogastric junction outflow obstruction, and non-achalasia dysphagia","volume":"113","author":"Blonski","year":"2018","journal-title":"Am J 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surgical research and practice","volume":"21","author":"Fernandez","year":"2017","journal-title":"J Gastrointest Surg"},{"issue":"19","key":"2021021010564803200_ref8","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1056\/NEJMoa1010502","article-title":"Pneumatic dilation versus laparoscopic Heller's myotomy for idiopathic achalasia","volume":"364","author":"Boeckxstaens","year":"2011","journal-title":"N Engl J Med"},{"issue":"2","key":"2021021010564803200_ref9","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1001\/jama.2019.8859","article-title":"Effect of peroral endoscopic motomy vs pneumatic dilation on symptom severity and treatment outcomes among treatment-naive patients with achalasia: a randomized clinical trial","volume":"322","author":"Ponds","year":"2019","journal-title":"JAMA"},{"issue":"23","key":"2021021010564803200_ref10","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.1056\/NEJMoa1905380","article-title":"Endoscopic or surgical myotomy in patients with idiopathic achalasia","volume":"381","author":"Werner","year":"2019","journal-title":"N Engl J Med"},{"issue":"8","key":"2021021010564803200_ref11","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1111\/j.1572-0241.2005.50141.x","article-title":"A measure of disease-specific health-related quality of life for achalasia","volume":"100","author":"Urbach","year":"2005","journal-title":"Am J Gastroenterol"},{"issue":"11","key":"2021021010564803200_ref12","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1038\/ajg.2016.402","article-title":"Achalasia-specific quality of life after pneumatic dilation or laparoscopic Heller myotomy with partial fundoplication: a multicenter, randomized clinical trial","volume":"111","author":"Chrystoja","year":"2016","journal-title":"Am J Gastroenterol"},{"issue":"1","key":"2021021010564803200_ref13","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/ajg.2012.318","article-title":"Esophageal stasis on a timed barium esophagogram predicts recurrent symptoms in patients with long-standing achalasia","volume":"108","author":"Rohof","year":"2013","journal-title":"Am J Gastroenterol"},{"issue":"6","key":"2021021010564803200_ref14","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1136\/gut.50.6.765","article-title":"Timed barium oesophagram: better predictor of long term success after pneumatic dilation in achalasia than symptom assessment","volume":"50","author":"Vaezi","year":"2002","journal-title":"Gut"}],"container-title":["Diseases of the 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