{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T12:49:51Z","timestamp":1763642991976,"version":"3.41.2"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T00:00:00Z","timestamp":1600387200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,6,14]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>We investigated changes in anastomotic stricture indexes (SIs) and stricture diameter (SD) between before and 6\u00a0months after the first dilatation in children with anastomotic stricture after esophageal atresia (EA) repair and identified predictors of medium-term dilatation success (success for at least 3\u00a0months). We retrospectively reviewed the records and measurement indexes of patients who underwent post-EA repair endoscopic balloon dilatation between November 2017 and August 2019 in our hospital. We identified diagnostic and performance indicators that predicted medium-term dilatation success by univariate and multivariate analyses and receiver operator characteristic (ROC) curve analysis. Sixty patients (34 boys and 26 girls) showed post-EA repair anastomotic stricture. Paired sample t-tests showed that SD (P\u2009&amp;lt;\u20090.001), upper pouch SI (U-SI, P\u2009&amp;lt;\u20090.001), lower pouch SI (L-SI, P\u2009&amp;lt;\u20090.001), upper pouch esophageal anastomotic SI (U-EASI, P\u2009&amp;lt;\u20090.001) and lower pouch EASI (L-EASI, P\u2009&amp;lt;\u20090.001) were significantly better at 6\u00a0months after than before the first dilatation. Logistic regression analysis showed that dilatation number (P\u2009=\u20090.002) and U-SI at 6\u00a0months after the first dilatation (P\u2009=\u20090.019) significantly predicted medium-term dilatation success. ROC curve analysis revealed that combining U-SI (cut-off value\u2009=\u200955.6%) and dilatation number (cut-off value\u2009=\u200910) had good accuracy in predicting medium-term dilatation success 6\u00a0months after the first dilatation (area under the curve-ROC: 0.95). In conclusion, endoscopic balloon dilatation significantly improved SD and SIs in children with post-EA repair anastomotic stricture. Dilatation number and U-SI at 6\u00a0months after the first dilatation were useful in predicting medium-term dilatation success and could represent a supplementary method to improve judgment regarding whether further dilatation is needed 6\u00a0months after the first dilatation.<\/jats:p>","DOI":"10.1093\/dote\/doaa103","type":"journal-article","created":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T04:24:24Z","timestamp":1600403064000},"source":"Crossref","is-referenced-by-count":6,"title":["Anastomotic stricture indexes for endoscopic balloon dilation after esophageal atresia repair: a single-center study"],"prefix":"10.1093","volume":"34","author":[{"given":"Jinshi","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Neonatal Surgery, The Affiliated Children's Hospital of Nanchang University, Nanchang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junmin","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Neonatal Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2029-3977","authenticated-orcid":false,"given":"Shen","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Neonatal Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neonatal Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Neonatal Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yichao","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Neonatal Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaiyun","family":"Hua","sequence":"additional","affiliation":[{"name":"Department of Neonatal Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuangshuang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neonatal Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leizhen","family":"Xia","sequence":"additional","affiliation":[{"name":"Assisted Reproductive Center, Jiangxi Maternal and Child Health Hospital, Nanchang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siyu","family":"Cai","sequence":"additional","affiliation":[{"name":"Center for Clinical Epidemiology & Evidence-based Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,9,18]]},"reference":[{"key":"2021061405192683700_ref1","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.giec.2015.09.002","article-title":"Endoscopic management of anastomotic esophageal strictures secondary to esophageal atresia","volume":"26","author":"Manfredi","year":"2016","journal-title":"Gastrointest Endosc 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