{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T19:12:14Z","timestamp":1786821134486,"version":"build-2736575974"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T00:00:00Z","timestamp":1607731200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,9,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The purpose of the current study was to clarify the relationship between clinical features of dysphagia after esophagectomy and preoperative sarcopenia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 187 cases were included in the current study. The psoas cross-sectional area on pre-treatment computed tomography was measured in thoracic esophageal cancer patients who underwent curative resection. The psoas muscle index (PMI) cut-off levels for sarcopenia were 6.36\u00a0cm2\/m2 for men and 3.92\u00a0cm2\/m2 for women. Swallowing function was evaluated using videofluoroscopic swallowing study (VFSS) and fiberoptic endoscopic evaluation of swallowing (FEES) at postoperative days 7\u201315, and classified according to the food intake level scale (FILS). Perioperative swallowing rehabilitation was performed in all cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the 187 included patients, the median PMI was 5.42\u00a0cm2\/m2 for men and 3.43\u00a0cm2\/m2 for women, and 133 cases (71%) met the sarcopenia criteria. The FILS &amp;lt;4 (no oral intake) was 15% in the non-sarcopenia group, and 38% in the sarcopenia group (P\u2009=\u20090.003). There was no significant difference in the incidence of postoperative complications, including pneumonia and re-admission due to pneumonia, between the two groups. Preoperative sarcopenia and recurrent laryngeal nerve palsy were be independent risk factors for postoperative dysphagia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Sarcopenic patients with esophageal cancer develop postoperative dysphagia more often than non-sarcopenic patients. Prehabilitation and nutritional support for patients with preoperative sarcopenia could play an important role to mitigate postoperative dysphagia.<\/jats:p><\/jats:sec>","DOI":"10.1093\/dote\/doaa121","type":"journal-article","created":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T07:40:03Z","timestamp":1607758803000},"source":"Crossref","is-referenced-by-count":30,"title":["Association of preoperative sarcopenia with postoperative dysphagia in patients with thoracic esophageal cancer"],"prefix":"10.1093","volume":"34","author":[{"given":"Shuhei","family":"Mayanagi","sequence":"first","affiliation":[{"name":"Department of Surgery, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aiko","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Keio University School of Medicine, Tokyo, 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