{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T04:59:16Z","timestamp":1781240356318,"version":"3.54.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2022,1,17]],"date-time":"2022-01-17T00:00:00Z","timestamp":1642377600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,12]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Endoscopic surveillance of adults with esophageal atresia is advocated, but the optimal surveillance strategy remains uncertain. This study aimed to provide recommendations on appropriate starting age and intervals of endoscopic surveillance in adults with esophageal atresia.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Participants underwent standardized upper endoscopies with biopsies. Surveillance intervals of 3\u20135\u00a0years were applied, depending on age and histopathological results. Patient\u2019s age and time to development of (pre)malignant lesions were calculated.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 271 patients with esophageal atresia (55% male; median age at baseline endoscopy 26.7 (range 15.6\u201368.5) years; colon interposition n\u2009=\u200917) were included. Barrett\u2019s esophagus was found in 19 (7%) patients (median age 32.3 (17.8\u201356.0) years at diagnosis). Youngest patient with a clinically relevant Barrett\u2019s esophagus was 20.9\u00a0years. Follow-up endoscopies were performed in 108 patients (40%; median follow-up time 4.6\u00a0years). During surveillance, four patients developed Barrett\u2019s esophagus but no dysplasia or cancer was found. One 45-year-old woman with a colon interposition developed an adenoma with high-grade dysplasia which was radically removed. Two new cases of esophageal carcinoma were diagnosed in patients (55 and 66\u00a0years old) who were not under surveillance. One of them had been curatively treated for esophageal carcinoma 13\u00a0years ago.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This study shows that endoscopic screening of patients with esophageal atresia, including those with a colon interposition, can be started at 20\u00a0years of age. Up to the age of 40\u00a0years a surveillance interval of 10\u00a0years appeared to be safe. Endoscopic surveillance may also be warranted for patients after curative esophageal cancer treatment.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/dote\/doab095","type":"journal-article","created":{"date-parts":[[2022,1,16]],"date-time":"2022-01-16T19:01:36Z","timestamp":1642359696000},"source":"Crossref","is-referenced-by-count":12,"title":["Recommendations for endoscopic surveillance after esophageal atresia repair in adults"],"prefix":"10.1093","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9921-7776","authenticated-orcid":false,"given":"Chantal A","family":"ten Kate","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery and Intensive Care , Erasmus MC Sophia Children's Hospital, Rotterdam, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7297-1098","authenticated-orcid":false,"given":"Anne-Fleur R L","family":"van 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