{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:59:18Z","timestamp":1767833958011,"version":"3.49.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,9,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Recent guidelines recommend screening for patients with chronic gastroesophageal reflux disease who have three or more additional risk factors for Barrett\u2019s esophagus (BE). Failure to screen high-risk individuals represents a missed opportunity in esophageal adenocarcinoma prevention and early detection. We aimed to determine the frequency of upper endoscopy and prevalence of BE and esophageal cancer in a cohort of United States veterans who possessed four or more risk factors for BE. All patients at VA New York Harbor Healthcare System with at least four risk factors for BE between 2012 and 2017 were identified. Procedure records were reviewed for upper endoscopies performed between January 2012 and December 2019. Multivariable logistic regression was used to determine risk factors associated with undergoing endoscopy and factors associated with BE and esophageal cancer. 4505 patients with at least four risk factors for BE were included. 828 patients (18.4%) underwent upper endoscopy, of which 42 (5.1%) were diagnosed with BE and 11 (1.3%) with esophageal cancer (10 adenocarcinoma; 1 squamous cell carcinoma). Among individuals who underwent upper endoscopy, risk factors associated with undergoing endoscopy included obesity (OR, 1.79; 95% CI, 1.41\u20132.30; P\u2009&amp;lt;\u20090.001) and chronic reflux (OR, 3.86; 95% CI, 3.04\u20134.90; P\u2009&amp;lt;\u20090.001). There were no individual risk factors associated with BE or BE\/esophageal cancer. In this retrospective analysis of patients with 4 or more risk factors for BE, fewer than one-fifth of patients underwent upper endoscopy, supporting the need for efforts aimed at improving BE screening rates.<\/jats:p>","DOI":"10.1093\/dote\/doad007","type":"journal-article","created":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T14:49:12Z","timestamp":1678373352000},"source":"Crossref","is-referenced-by-count":5,"title":["Veterans with multiple risk factors for Barrett\u2019s esophagus are infrequently evaluated with upper endoscopy"],"prefix":"10.1093","volume":"36","author":[{"given":"Brooks R","family":"Crowe","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology , Department of Medicine, , Brooklyn, NY , USA"},{"name":"SUNY Downstate Medical Center , Department of Medicine, , Brooklyn, NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9791-6490","authenticated-orcid":false,"given":"Anna","family":"Krigel","sequence":"additional","affiliation":[{"name":"Division of Digestive and Liver Diseases , Department of Medicine, , New York, NY , USA"},{"name":"Columbia University Medical Center , Department of Medicine, , New York, NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tian","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medicine, SUNY Downstate Medical Center , Brooklyn, NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rozina","family":"Haile","sequence":"additional","affiliation":[{"name":"Department of Medicine, SUNY Downstate Medical Center , Brooklyn, NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Firas","family":"Al-Ani","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology , Department of Medicine, , Brooklyn, NY , USA"},{"name":"SUNY Downstate Medical Center , Department of Medicine, , Brooklyn, NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Lebwohl","sequence":"additional","affiliation":[{"name":"Division of Digestive and Liver Diseases , Department of Medicine, , New York, NY , USA"},{"name":"Columbia University Medical Center , Department of Medicine, , New York, NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian A","family":"Abrams","sequence":"additional","affiliation":[{"name":"Division of Digestive and Liver Diseases , Department of Medicine, , New York, NY , USA"},{"name":"Columbia University Medical Center , Department of Medicine, , New York, NY , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1960-4133","authenticated-orcid":false,"given":"James L","family":"Araujo","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology , Department of Internal Medicine, , Seattle, WA , USA"},{"name":"University of Washington School of Medicine , Department of Internal Medicine, , Seattle, WA , USA"},{"name":"Division of Gastroenterology, Veterans Affairs Puget Sound Healthcare System , Seattle, WA , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,3,9]]},"reference":[{"key":"2023090116253502500_ref1","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1002\/cncr.27834","article-title":"Trends in esophageal adenocarcinoma incidence and mortality","volume":"119","author":"Hur","year":"2013","journal-title":"Cancer"},{"key":"2023090116253502500_ref2","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.canep.2016.01.013","article-title":"The epidemic of oesophageal carcinoma: where are we 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the National Veteran Population","volume":"62","author":"Gawron","year":"2017","journal-title":"Dig Dis Sci"}],"container-title":["Diseases of the 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