{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T05:42:52Z","timestamp":1782538972355,"version":"3.54.5"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,2,29]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>To compare 5-year gastroesophageal reflux outcomes following Laparoscopic Vertical Sleeve Gastrectomy (LVSG) and Laparoscopic Roux-en-Y gastric bypass (LRYGB) based on high quality randomized controlled trials (RCTs). We conducted a sub-analysis of our systematic review and meta-analysis of RCTs of primary LVSG and LRYGB procedures in adults for 5-year post-operative complications (PROSPERO CRD42018112054). Electronic databases were searched from January 2015 to July 2021 for publications meeting inclusion criteria. The Hartung-Knapp-Sidik-Jonkman random effects model was utilized to estimate weighted mean differences where meta-analysis was possible. Bias and certainty of evidence was assessed using the Cochrane Risk of Bias Tool 2 and GRADE. Four RCTs were included (LVSG n = 266, LRYGB n = 259). An increase in adverse GERD outcomes were observed at 5 years postoperatively in LVSG compared to LRYGB in all outcomes considered: Overall worsened GERD, including the development de novo GERD, occurred more commonly following LVSG compared to LRYGB (OR 5.34, 95% CI 1.67 to 17.05; p = 0.02; I2 = 0%; (Moderate level of certainty); Reoperations to treat severe GERD (OR 7.22, 95% CI 0.82 to 63.63; p = 0.06; I2 = 0%; High level of certainty) and non-surgical management for worsened GERD (OR 3.42, 95% CI 1.16 to 10.05; p = 0.04; I2 = 0%; Low level of certainty) was more common in LVSG patients. LVSG is associated with the development and worsening of GERD symptoms compared to LRYGB at 5 years postoperatively leading to either introduction\/increased pharmacological requirement or further surgical treatment. Appropriate patient\/surgical selection is critical to minimize these postoperative risks.<\/jats:p>","DOI":"10.1093\/dote\/doad063","type":"journal-article","created":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T00:53:46Z","timestamp":1699404826000},"source":"Crossref","is-referenced-by-count":8,"title":["Gastroesophageal reflux disease following laparoscopic vertical sleeve gastrectomy and laparoscopic roux-en-Y gastric bypass: meta-analysis and systematic review of 5-year data"],"prefix":"10.1093","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2589-2338","authenticated-orcid":false,"given":"Muhammed A","family":"Memon","sequence":"first","affiliation":[{"name":"School of Mathematics , Physics and Computing and Centre for Health Research, , Toowoomba, QLD , Australia"},{"name":"University of Southern Queensland , Physics and Computing and Centre for Health Research, , Toowoomba, QLD , Australia"},{"name":"Sunnybank Obesity Centre & South & East Queensland Surgery (SEQS), McCullough Centre , Suite 9, 259 McCullough Street, Sunnybank, QLD , Australia"},{"name":"Mayne Medical School , School of Medicine, , Brisbane, QLD , Australia"},{"name":"University of Queensland , School of Medicine, , Brisbane, QLD , Australia"},{"name":"Faculty of Health Sciences and Medicine, Bond University , Gold Coast, QLD , Australia"},{"name":"Faculty of Health and Social Science, Bolton University , Bolton, Lancashire , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Osland","sequence":"additional","affiliation":[{"name":"Department of Dietetics and Food Services, Royal Brisbane and Women\u2019s Hospital , Herston, QLD 4019 , Australia"},{"name":"Department of Human Movements and Nutrition, University of Queensland , Brisbane, QLD , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rossita M","family":"Yunus","sequence":"additional","affiliation":[{"name":"Institute of Mathematical Sciences, Universiti Malaya , Kuala Lumpur , Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khorshed","family":"Alam","sequence":"additional","affiliation":[{"name":"School of Business , and Centre for Health Research, , Toowoomba, QLD 4350 , Australia"},{"name":"University of Southern Queensland , and Centre for Health Research, , Toowoomba, QLD 4350 , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahirul","family":"Hoque","sequence":"additional","affiliation":[{"name":"School of Mathematics , Physics and Computing, , Toowoomba, QLD , Australia"},{"name":"University of Sourthern Queensland , Physics and Computing, , Toowoomba, QLD , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahjahan","family":"Khan","sequence":"additional","affiliation":[{"name":"School of Mathematics , Physics and Computing and Centre for Health Research, , Toowoomba, QLD , Australia"},{"name":"University of Southern Queensland , Physics 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