{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T00:04:22Z","timestamp":1793059462482,"version":"4.5.0"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Esophageal manometry is utilized for the evaluation and classification of esophageal motility disorders. EndoFlip has been introduced as an adjunctive test to evaluate esophagogastric junction (EGJ) distensibility. Treatment options for achalasia and EGJ outflow obstruction (EGJOO) include pneumatic dilation, myotomy, and botulinum toxin. Recently, a therapeutic 30\u00a0mm hydrostatic balloon dilator (EsoFLIP, Medtronic, Minneapolis, MN, USA) has been introduced, which uses impedance planimetry technology like EndoFlip. We performed a systematic review to evaluate the safety and efficacy of EsoFLIP in the management of esophageal motility disorders. A systematic literature search was performed with Medline, Embase, Web of science, and Cochrane library databases from inception to November 2022 to identify studies utilizing EsoFLIP for management of esophageal motility disorders. Our primary outcome was clinical success, and secondary outcomes were adverse events. Eight observational studies including 222 patients met inclusion criteria. Diagnoses included achalasia (158), EGJOO (48), post-reflux surgery dysphagia (8), and achalasia-like disorder (8). All studies used 30\u00a0mm maximum balloon dilation except one which used 25\u00a0mm. The clinical success rate was 68.7%. Follow-up duration ranged from 1\u00a0week to a mean of 5.7\u00a0months. Perforation or tear occurred in four patients. EsoFLIP is a new therapeutic option for the management of achalasia and EGJOO and appears to be effective and safe. Future comparative studies with other therapeutic modalities are needed to understand its role in the management of esophageal motility disorders.<\/jats:p>","DOI":"10.1093\/dote\/doae036","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T18:53:54Z","timestamp":1712602434000},"source":"Crossref","is-referenced-by-count":12,"title":["Safety and efficacy of EsoFLIP dilation in patients with esophageal dysmotility: a systematic review"],"prefix":"10.1093","volume":"37","author":[{"given":"Umair","family":"Iqbal","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Wellspan York Hospital , York, PA , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2738-2606","authenticated-orcid":false,"given":"Michael","family":"Yodice","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Geisinger Medical Center , Danville, PA , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zohaib","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Toledo Medical Center , Toledo, OH , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hafsa","family":"Anwar","sequence":"additional","affiliation":[{"name":"Department of Medicine, Capital Health Regional Medical Center , Trenton, NJ , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syeda Faiza","family":"Arif","sequence":"additional","affiliation":[{"name":"Dow University of Health Sciences , Karachi , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wade M","family":"Lee-Smith","sequence":"additional","affiliation":[{"name":"Department of University Libraries, University of Toledo Medical Center , Toledo, OH , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David L","family":"Diehl","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Geisinger Medical Center , Danville, PA , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"issue":"12","key":"2024080106274897900_ref1","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1038\/ajg.2016.454","article-title":"Evaluation of esophageal motility utilizing the functional lumen imaging probe","volume":"111","author":"Carlson","year":"2016","journal-title":"Am J Gastroenterol"},{"issue":"2","key":"2024080106274897900_ref2","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.gie.2019.04.231","article-title":"ASGE guideline on the management of achalasia","volume":"91","author":"Khashab","year":"2020","journal-title":"Gastrointest 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