{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:49:17Z","timestamp":1753876157617,"version":"3.41.2"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T00:00:00Z","timestamp":1718064000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>High-resolution esophageal manometry [HRM] has become the gold standard for the evaluation of esophageal motility disorders. It is unclear whether there are HRM differences in diagnostic outcome based on regional or geographic distribution. The diagnostic outcome of HRM in a diverse geographical population of Mexico was compared and determined if there is variability in diagnostic results among referral centers. Consecutive patients referred for HRM during 2016\u20132020 were included. Four major referral centers in Mexico participated in the study: northeastern, southeastern, and central (Mexico City, two centers). All studies were interpreted by experienced investigators using Chicago Classification 3 and the same technology. A total of 2293 consecutive patients were included. More abnormal studies were found in the center (61.3%) versus south (45.8%) or north (45.2%) P\u00a0&amp;lt;\u20090.001. Higher prevalence of achalasia was noted in the south (21.5%) versus center (12.4%) versus north (9.5%) P\u00a0&amp;lt;\u20090.001. Hypercontractile disorders were more common in the north (11.0%) versus the south (5.2%) or the center (3.6%) P.001. A higher frequency of weak peristalsis occurred in the center (76.8%) versus the north (74.2%) or the south (69.2%) P\u00a0&amp;lt;\u20090.033. Gastroesophageal junction obstruction was diagnosed in (7.2%) in the center versus the (5.3%) in the north and (4.2%) in the south p.141 (ns). This is the first study to address the diagnostic outcome of HRM in diverse geographical regions of Mexico. We identified several significant diagnostic differences across geographical centers. Our study provides the basis for further analysis of the causes contributing to these differences.<\/jats:p>","DOI":"10.1093\/dote\/doae049","type":"journal-article","created":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T20:00:51Z","timestamp":1718049651000},"source":"Crossref","is-referenced-by-count":1,"title":["Diagnostic differences in high-resolution esophageal motility in a large Mexican cohort based on geographic distribution"],"prefix":"10.1093","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5295-3781","authenticated-orcid":false,"given":"Genaro","family":"V\u00e1zquez-Elizondo","sequence":"first","affiliation":[{"name":"Gastroenterology Department, Centro de Enfermedades Digestivas ONCARE , Monterrrey, Nuevo Le\u00f3n ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Mar\u00eda","family":"Remes-Troche","sequence":"additional","affiliation":[{"name":"Gastroenterology Department , Laboratorio de Motilidad Gastrointestinal y Fisiolog\u00eda Digestiva, , Veracruz ,","place":["M\u00e9xico"]},{"name":"Instituto de Investigaciones M\u00e9dico-Biol\u00f3gicas, Universidad Veracruzana , Laboratorio de Motilidad Gastrointestinal y Fisiolog\u00eda Digestiva, , Veracruz ,","place":["M\u00e9xico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel \u00c1ngel","family":"Valdovinos-D\u00edaz","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n , Mexico City ,","place":["M\u00e9xico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrique","family":"Coss-Adame","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n , Mexico City ,","place":["M\u00e9xico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edgardo Su\u00e1rez","family":"Mor\u00e1n","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Hospital Espa\u00f1ol , Mexico City ,","place":["M\u00e9xico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sami R","family":"Achem","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Mayo College of Medicine, Mayo Clinic , Florida ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,6,11]]},"reference":[{"issue":"5","key":"2024100305361176900_ref1","doi-asserted-by":"crossref","first-page":"e14043","DOI":"10.1111\/nmo.14043","article-title":"ESNM HRM consensus group. 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