{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:48:46Z","timestamp":1753876126673,"version":"3.41.2"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T00:00:00Z","timestamp":1730937600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,7]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Managing esophageal squamous cell carcinoma (ESCC) in patients with a history of cervical radiotherapy for a head and neck cancer (HNC) often requires a careful evaluation of esophagectomy due to concerns regarding complications and prognosis. This study evaluates the periesophagectomy and oncological outcomes of such patients. Patients diagnosed with ESCC between January 2010 and August 2023 and who had undergone esophagectomy with cervical anastomosis were retrospectively reviewed. Patients were categorized into two groups based on the presence (group 1) or absence (group 2) of a history of radiotherapy for as HNC. After 1: 2 propensity score matching, the perioperative and oncological outcomes, including overall survival (OS) and recurrence-free survival (RFS), were evaluated. A total of 481 patients, 32 in group 1 and 449 in group 2, were included. After matching, group 1 patients and 64 patients in the group 2 were analyzed. All the patients in group 1 were males, and their mean age was 56\u00a0years. The median radiation dose was 69\u00a0Gy. The rates of anastomosis leakage, pneumonia, respiratory failure, and reoperation were comparable between the two groups. However, vocal cord palsy occurred more frequently in group 1, particularly in those with recurrent laryngeal nerve lymph node dissection (37.5%). The 3-year OS (69.6% vs. 75.2%; p\u2009=\u20090.26) and RFS (50.8% vs. 55.9%; p\u2009=\u20090.63) were similar between groups 1 and 2. In conclusion, perioperative and oncological outcomes were comparable between ESCC patients with and without prior HNC radiotherapy, supporting esophagectomy as a feasible option.<\/jats:p>","DOI":"10.1093\/dote\/doae099","type":"journal-article","created":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T17:39:52Z","timestamp":1731001192000},"source":"Crossref","is-referenced-by-count":0,"title":["Managing esophageal squamous cell carcinoma after cervical radiotherapy for a head and neck cancer: esophagectomy remains a viable option"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-0284-3570","authenticated-orcid":false,"given":"Chia","family":"Liu","sequence":"first","affiliation":[{"name":"Division of Thoracic Surgery , Department of Surgery, , Taipei,","place":["Taiwan"]},{"name":"Taipei Veterans General Hospital , Department of Surgery, , Taipei,","place":["Taiwan"]},{"name":"School of Medicine, National Yang Ming Chiao Tung University , Taipei,","place":["Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tien-Li","family":"Lan","sequence":"additional","affiliation":[{"name":"School of Medicine, National Yang Ming Chiao Tung University , Taipei,","place":["Taiwan"]},{"name":"Department of Heavy Particles and Radiation Oncology, Taipei Veterans General Hospital , Taipei,","place":["Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3697-669X","authenticated-orcid":false,"given":"Ping-Chung","family":"Tsai","sequence":"additional","affiliation":[{"name":"School of Medicine, National Yang Ming Chiao Tung University , Taipei,","place":["Taiwan"]},{"name":"Division of Thoracic Surgery , Department of Surgery, , Kaohsiung,","place":["Taiwan"]},{"name":"Kaohsiung Veterans General Hospital , Department of Surgery, , Kaohsiung,","place":["Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling-I","family":"Chien","sequence":"additional","affiliation":[{"name":"Department of Nursing, Taipei Veterans General Hospital , Taipei,","place":["Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chien-Sheng","family":"Huang","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery , Department of Surgery, , Taipei,","place":["Taiwan"]},{"name":"Taipei Veterans General Hospital , Department of Surgery, , Taipei,","place":["Taiwan"]},{"name":"School of Medicine, National Yang Ming Chiao Tung University , Taipei,","place":["Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pin-I","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Medicine, National Yang Ming Chiao Tung University , Taipei,","place":["Taiwan"]},{"name":"Department of Heavy Particles and Radiation Oncology, Taipei Veterans General 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