{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T22:46:31Z","timestamp":1765233991349,"version":"3.41.2"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T00:00:00Z","timestamp":1746230400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,3]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Caustic esophageal injury can cause severe morbidity and mortality. Despite the need for emergent treatment, individual experience in diagnosis and management can be limited. Computed tomography (CT) has emerged as a promising non-invasive modality for assessing injury severity, but the clinical utility of both CT and endoscopy should be investigated. A systematic review was conducted following PRISMA guidelines. A comprehensive search of the PubMed database identified relevant articles published from January 1, 2000 to December 31, 2023. Inclusion criteria encompassed studies investigating the use of CT and\/or endoscopy in diagnosing and managing caustic esophageal injury. Twelve articles were selected from a pool of 931 studies. Findings suggested that CT was superior in diagnostic capability to endoscopy in high-grade injury and stricture formation, but less so for low grade injuries. Diagnostic algorithms incorporating imaging with laboratory studies have emerged in the literature, which are promising pending additional validation. CT can serve as a valuable, non-invasive tool in the initial evaluation of caustic esophageal injury and is postulated to accurately predict both the need for emergent surgery and the risk of stricture formation. However, CT should not replace but rather complement the use of endoscopy to comprehensively evaluate these potentially highly morbid situations.<\/jats:p>","DOI":"10.1093\/dote\/doaf037","type":"journal-article","created":{"date-parts":[[2025,5,18]],"date-time":"2025-05-18T03:40:26Z","timestamp":1747539626000},"source":"Crossref","is-referenced-by-count":1,"title":["The role of computed tomography and endoscopy in caustic esophageal injury in adults: a systematic review"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0039-5677","authenticated-orcid":false,"given":"Elisa","family":"Bass","sequence":"first","affiliation":[{"name":"Mayo Clinic Alix School of Medicine, Mayo Clinic Arizona , Phoenix, AZ ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John Asher","family":"Jenkins","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Mayo Clinic Arizona , Phoenix, AZ ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan M","family":"Farina","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Mayo Clinic Arizona , Phoenix, AZ ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Saleeb","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Mayo Clinic Arizona , Phoenix, AZ ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Staci E","family":"Beamer","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Mayo Clinic Arizona , Phoenix, AZ ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawn E","family":"Jaroszewski","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Mayo Clinic Arizona , Phoenix, AZ ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samine","family":"Ravanbakhsh","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Mayo Clinic Arizona , Phoenix, AZ ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia","family":"Benz","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Mayo Clinic Arizona , Phoenix, AZ ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Reck dos Santos","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Mayo Clinic Arizona , Phoenix, AZ ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"D\u2019Cunha","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Mayo Clinic Arizona , Phoenix, AZ ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,5,18]]},"reference":[{"key":"2025052712492200300_ref1","doi-asserted-by":"crossref","first-page":"274","DOI":"10.4253\/wjge.v10.i10.274","article-title":"Role of endoscopy in caustic injury of the esophagus","volume":"10","author":"Methasate","year":"2018","journal-title":"World J Gastrointest Endosc"},{"key":"2025052712492200300_ref2","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1164\/ajrccm.165.8.2104105","article-title":"Surgical aspects of esophageal disease: perforation and caustic injury","volume":"165","author":"Zwischenberger","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"2025052712492200300_ref3","doi-asserted-by":"crossref","first-page":"3918","DOI":"10.3748\/wjg.v19.i25.3918","article-title":"Caustic injury of the upper gastrointestinal tract: a comprehensive review","volume":"19","author":"Contini","year":"2013","journal-title":"World J Gastroenterol"},{"key":"2025052712492200300_ref4","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1016\/S0140-6736(16)30313-0","article-title":"Caustic ingestion","volume":"389","author":"Chirica","year":"2017","journal-title":"The Lancet"},{"key":"2025052712492200300_ref5"},{"key":"2025052712492200300_ref6","first-page":"55","article-title":"Risk-of-bias VISualization (robvis): an R package and shiny web app for visualizing risk-of-bias assessments. 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