{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:17:59Z","timestamp":1787008679997,"version":"build-2736575974"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T00:00:00Z","timestamp":1758067200000},"content-version":"vor","delay-in-days":16,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>Esophageal food impaction (EFI) is the leading complication in patients with undiagnosed eosinophilic esophagitis (EoE). Limited data exists on pre-hospital care, in-hospital management, and post-hospital follow-up in suspected EoE-associated EFI. This study aims to assess deviations between real-life management and guideline-based recommendations in suspected EoE-associated EFI. This retrospective multicenter study analyzed data from four major Swiss gastroenterology units on patients with EoE-associated EFI. Patients with GERD-related strictures or esophageal cancer were excluded. Data on demographics, emergency department (ED), endoscopy management, and follow-up were obtained from electronic health records. Associations between clinical factors and odds of biopsy were analyzed using logistic regression. Between January 2015 and December 2020, 198 EFI cases (median age 51\u00a0years, 29.8% female, 28% with previous EFI) were recorded. Patient delay\u2014the time between symptom onset and ED admission\u2014was ~ 270\u00a0minutes. Nearly all patients (94%) required endoscopic bolus removal. The median time from ED presentation to endoscopy was ~150\u00a0minutes. Esophageal biopsies were taken in just over half of the individuals (n\u2009=\u200997, 52%), leading to a new EoE diagnosis in 71 (68.9% of those biopsied). Biopsy odds decreased significantly with older age (OR 0.96; 95% CI 0.94\u20130.98, P &amp;lt;\u00a00.05) and known EoE (OR 0.26; 95% 0.09\u20130.69, P &amp;lt;\u00a00.05). Although EoE is a leading cause of EFI, too few patients with a high baseline probability of EoE undergo biopsy in the emergency setting. Among those biopsied, the majority received a new EoE diagnosis, highlighting the importance of histological assessment.<\/jats:p>","DOI":"10.1093\/dote\/doaf073","type":"journal-article","created":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T11:43:42Z","timestamp":1756295022000},"source":"Crossref","is-referenced-by-count":2,"title":["Wide discrepancy between best practice recommendations and real-life management of suspected eosinophilic esophagitis-associated food bolus impaction"],"prefix":"10.1093","volume":"38","author":[{"given":"Yangzom","family":"Siegfried","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Zurich , Zurich ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7331-587X","authenticated-orcid":false,"given":"Jagoda","family":"Pokryszka","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna , Vienna ,","place":["Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petr","family":"Hruz","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Center for Gastrointestinal and Liver Diseases St. Clara Hospital and University Hospital of Basel , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Buetikofer","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Luzerner Kantonsspital (LUKS) , Lucerne ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8507-0619","authenticated-orcid":false,"given":"Bernhard","family":"Morell","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology & Hepatology, Stadtspital Triemli Zurich , Zurich ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fritz R","family":"Murray","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology & Hepatology, Stadtspital Triemli Zurich , Zurich ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekaterina","family":"Safroneeva","sequence":"additional","affiliation":[{"name":"Institute of Social and Preventive Medicine, University of Bern , Bern ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Kreienbuehl","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Zurich , Zurich ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Greuter","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, EOC Lugano, Universit\u00e0 della Svizzera italiana , Lugano ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Straumann","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Zurich , Zurich ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Rogler","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Zurich , Zurich ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Biedermann","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Zurich , Zurich ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Schoepfer","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne , Lausanne ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Schreiner","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Zurich , Zurich ,","place":["Switzerland"]},{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna , Vienna ,","place":["Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,9,17]]},"reference":[{"key":"2025091919234967900_ref1","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1097\/MPG.0b013e3181de7685","article-title":"Comparative analysis of fc\u03b5ri expression patterns in patients with eosinophilic and reflux esophagitis","volume":"51","author":"Yen","year":"2010","journal-title":"J Pediatr Gastroenterol 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In: Gastrointestinal Endoscopy","author":"Aceves","year":"2022"},{"key":"2025091919234967900_ref30","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jaci.2011.02.040","article-title":"Eosinophilic esophagitis: updated consensus recommendations for children and adults","volume":"128","author":"Liacouras","year":"2011","journal-title":"Journal of Allergy and Clinical Immunology Mosby Inc"},{"key":"2025091919234967900_ref31","doi-asserted-by":"crossref","DOI":"10.1007\/s00508-025-02542-6","article-title":"No increase of biopsy rates despite high rates of probable eosinophilic esophagitis in patients with esophageal food impaction","author":"Neumann","year":"2025","journal-title":"Wien Klin Wochenschr"},{"key":"2025091919234967900_ref32","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12113768","article-title":"Diagnosis of eosinophilic esophagitis at the time of Esophageal food impaction","volume":"12","author":"Lee","year":"2023","journal-title":"J Clin Med"},{"key":"2025091919234967900_ref33","article-title":"Loss to follow-up after food impaction among patients with and without eosinophilic esophagitis","volume":"32","author":"Chang","year":"2020","journal-title":"Dis Esophagus"},{"key":"2025091919234967900_ref34","doi-asserted-by":"crossref","DOI":"10.1007\/s10620-024-08590-8","article-title":"Performing Esophageal biopsies is safe during upper endoscopy for food impaction but are underperformed in certain populations","author":"Barlowe","year":"2024","journal-title":"Dig Dis Sci"}],"container-title":["Diseases of the Esophagus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/dote\/article-pdf\/38\/5\/doaf073\/64302540\/doaf073.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/dote\/article-pdf\/38\/5\/doaf073\/64302540\/doaf073.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T23:23:56Z","timestamp":1758324236000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/dote\/article\/doi\/10.1093\/dote\/doaf073\/8256730"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,1]]},"references-count":34,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/dote\/doaf073","relation":{},"ISSN":["1120-8694","1442-2050"],"issn-type":[{"value":"1120-8694","type":"print"},{"value":"1442-2050","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,10]]},"published":{"date-parts":[[2025,9,1]]},"article-number":"doaf073"}}