{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T19:15:05Z","timestamp":1783624505202,"version":"3.55.0"},"reference-count":61,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,2]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Esophagectomy for esophageal cancer significantly impacts health-related quality of life. Identification of these predictors could enable early risk stratification and guide supportive care strategies preoperatively and immediately postoperatively. We aimed to systematically map preoperative and surgical factors associated with postoperative health-related quality of life in patients undergoing esophagectomy for esophageal cancer.<\/jats:p>\n                  <jats:p>MEDLINE, CENTRAL, EMBASE and Web of Science were searched through November 2024. We included cohort and case\u2013control studies examining preoperative and surgical factors affecting postoperative health-related quality of life.<\/jats:p>\n                  <jats:p>Nine studies (2285 patients) from Asia and Europe (2013\u20132021) met the inclusion criteria. EORTC QLQ-C30 questionnaires were used in all studies. Eight factors showed significant associations with postoperative health-related quality of life in multivariate analysis: age, sex, sarcopenia, tumor location, neoadjuvant therapy (NAT), surgical approach (open versus minimally invasive; transthoracic versus transhiatal), circumferential margin status, and systemic immune\u2013inflammation index. Temporal analysis revealed distinct patterns: early postoperative health-related quality of life (\u2264 6\u00a0months) was influenced by age, sex, sarcopenia, tumor location, NAT and margin status. In contrast, late health-related quality of life (&amp;gt; 6\u00a0months) was associated with age, sex, NAT, surgical approach, and systemic immune-inflammation index.Multiple preoperative and surgical predictors of health-related quality of life after esophagectomy were identified, with distinct factors affecting between the first \u22646 postoperative months and subsequently. These findings emphasize the importance of systematically assessing preoperative and surgical factors when developing supportive care strategies.<\/jats:p>","DOI":"10.1093\/dote\/doag071","type":"journal-article","created":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T19:09:39Z","timestamp":1783624179000},"source":"Crossref","is-referenced-by-count":0,"title":["Predictors of postoperative health-related quality of life in patients with esophageal cancer: a scoping review"],"prefix":"10.1093","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-1607-819X","authenticated-orcid":false,"given":"Hanako","family":"Himematsu","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine, University of Tsukuba Hospital , Tsukuba ,","place":["Japan"]},{"name":"Doctoral Program in Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba , Tsukuba ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Faculty of Rehabilitation, Kansai Medical University , Hirakata ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiji","family":"Matsumori","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Shinshu University Hospital , Nagano ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiro","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Okayama University Hospital , Okayama ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuyoshi","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Division of Rehabilitation Medicine, Shizuoka Cancer Center , Shizuoka ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shusuke","family":"Toyama","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy Sciences, Nagasaki University Graduate School of Biomedical Sciences , Nagasaki ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8224-1294","authenticated-orcid":false,"given":"Kazuki","family":"Okura","sequence":"additional","affiliation":[{"name":"Division of Rehabilitation, Akita University Hospital , Akita ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Sato","sequence":"additional","affiliation":[{"name":"Faculty of Rehabilitation, Kawasaki University of Medical Welfare , Okayama ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuya","family":"Tsuji","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, National Cancer Center Hospital East, Kashiwa , Chiba ,","place":["Japan"]},{"name":"Department of Rehabilitation Medicine, Keio University School of Medicine , Shinjuku ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsuyoshi","family":"Harada","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, National Cancer Center Hospital East, Kashiwa , Chiba ,","place":["Japan"]},{"name":"Department of Rehabilitation Medicine, Keio University School of Medicine , Shinjuku ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,7,9]]},"reference":[{"issue":"10466","key":"2026070915093163600_ref1","doi-asserted-by":"publisher","first-page":"1991","DOI":"10.1016\/S0140-6736(24)02226-8","article-title":"Oesophageal cancer","volume":"404","author":"Yang","year":"2024","journal-title":"Lancet [Internet]"},{"issue":"2","key":"2026070915093163600_ref2","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1097\/SLA.0000000000002611","article-title":"Benchmarking complications associated with esophagectomy","volume":"269","author":"Low","year":"2019","journal-title":"Annals of Surgery [Internet]"},{"issue":"10447","key":"2026070915093163600_ref3","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/S0140-6736(24)00745-1","article-title":"Doublet chemotherapy, triplet chemotherapy, or doublet chemotherapy combined with radiotherapy as neoadjuvant treatment for locally advanced oesophageal cancer (JCOG1109 NExT): a randomised, controlled, open-label, phase 3 trial","volume":"404","author":"Kato","year":"2024","journal-title":"Lancet [Internet]"},{"issue":"1","key":"2026070915093163600_ref4","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1097\/SLA.0b013e3182590603","article-title":"Outcomes after minimally invasive esophagectomy: review of over 1000 patients","volume":"256","author":"Luketich","year":"2012","journal-title":"Ann Surg [Internet]"},{"issue":"2","key":"2026070915093163600_ref5","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1002\/cncr.28382","article-title":"A global analysis of multitrial data investigating quality of life and symptoms as prognostic factors for survival in different tumor sites: quality of life prognostic for survival","volume":"120","author":"Quinten","year":"2014","journal-title":"Cancer [Internet]"},{"issue":"10","key":"2026070915093163600_ref6","doi-asserted-by":"publisher","first-page":"2631","DOI":"10.1007\/s11136-024-03691-3","article-title":"Global quality of life and mortality risk in patients with cancer: a systematic review and meta-analysis","volume":"33","author":"Fukushima","year":"2024","journal-title":"Qual Life Res [Internet]"},{"issue":"5","key":"2026070915093163600_ref7","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1200\/JCO.2012.46.6854","article-title":"American Society of Clinical Oncology statement: achieving high-quality cancer survivorship care","volume":"31","author":"McCabe","year":"2013","journal-title":"J Clin Oncol [Internet]"},{"issue":"1","key":"2026070915093163600_ref8","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/s10388-021-00874-6","article-title":"Health-related quality of life after esophagectomy in patients with esophageal cancer","volume":"19","author":"Toh","year":"2022","journal-title":"Esophagus [Internet]"},{"key":"2026070915093163600_ref9","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.ejca.2016.09.032","article-title":"Health-related quality of life 10 years after oesophageal cancer surgery","volume":"69","author":"Schandl","year":"2016","journal-title":"Eur J Cancer [Internet]"},{"issue":"1","key":"2026070915093163600_ref10","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1586\/egh.11.91","article-title":"Quality of life after esophagectomy for cancer","volume":"6","author":"Dj\u00e4rv","year":"2012","journal-title":"Expert Rev Gastroenterol Hepatol [Internet]"},{"issue":"4","key":"2026070915093163600_ref11","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1016\/j.jtcvs.2014.12.063","article-title":"Outcomes, quality of life, and survival after esophagectomy for squamous cell carcinoma: a propensity score-matched comparison of operative approaches","volume":"149","author":"Wang","year":"2015","journal-title":"J Thorac Cardiovasc Surg [Internet]"},{"issue":"4","key":"2026070915093163600_ref12","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1002\/jso.23837","article-title":"Impacts of anastomotic complications on the health-related quality of life after esophagectomy: HRQL after esophagectomy","volume":"111","author":"Huang","year":"2015","journal-title":"J Surg Oncol [Internet]"},{"issue":"12","key":"2026070915093163600_ref13","doi-asserted-by":"publisher","first-page":"1538","DOI":"10.1016\/j.ejca.2015.05.006","article-title":"Long-term quality of life after oesophagectomy with gastric conduit interposition for cancer","volume":"51","author":"Akkerman","year":"2015","journal-title":"Eur J Cancer [Internet]"},{"issue":"14","key":"2026070915093163600_ref14","doi-asserted-by":"publisher","first-page":"1615","DOI":"10.1200\/JCO.2011.40.3568","article-title":"Influence of major postoperative complications on health-related quality of life among long-term survivors of esophageal cancer surgery","volume":"30","author":"Derogar","year":"2012","journal-title":"J Clin Oncol [Internet]"},{"issue":"1","key":"2026070915093163600_ref15","doi-asserted-by":"publisher","first-page":"e140","DOI":"10.1097\/SLA.0000000000003829","article-title":"Assessment of health related quality of life and digestive symptoms in long-term, disease free survivors after esophagectomy","volume":"275","author":"Boshier","year":"2022","journal-title":"Ann Surg [Internet]"},{"issue":"1","key":"2026070915093163600_ref16","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1080\/1364557032000119616","article-title":"Scoping studies: towards a methodological framework","volume":"8","author":"Arksey","year":"2005","journal-title":"Int J Soc Res Methodol [Internet]"},{"issue":"1","key":"2026070915093163600_ref17","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1186\/1748-5908-5-69","article-title":"Scoping studies: advancing the methodology","volume":"5","author":"Levac","year":"2010","journal-title":"Implement Sci [Internet]"},{"issue":"7","key":"2026070915093163600_ref18","doi-asserted-by":"publisher","first-page":"467","DOI":"10.7326\/M18-0850","article-title":"PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation","volume":"169","author":"Tricco","year":"2018","journal-title":"Ann Intern Med [Internet]"},{"issue":"1","key":"2026070915093163600_ref19","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1186\/s13643-016-0384-4","article-title":"Rayyan-a web and mobile app for systematic reviews","volume":"5","author":"Ouzzani","year":"2016","journal-title":"Syst Rev [Internet]"},{"issue":"Pt 1","key":"2026070915093163600_ref20","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1016\/j.envint.2018.07.015","article-title":"Identifying the PECO: a framework for formulating good questions to explore the association of environmental and other exposures with health outcomes","volume":"121","author":"Morgan","year":"2018","journal-title":"Environ Int [Internet]"},{"issue":"11","key":"2026070915093163600_ref21","doi-asserted-by":"publisher","first-page":"CD010820","DOI":"10.1002\/14651858.CD010820.pub2","article-title":"Interventions for improving upper limb function after stroke","author":"Pollock","year":"2014","journal-title":"Cochrane Database Syst Rev [Internet]"},{"issue":"12","key":"2026070915093163600_ref22","doi-asserted-by":"publisher","first-page":"1963","DOI":"10.1200\/JCO.2008.20.5864","article-title":"Predictors of postoperative quality of life after esophagectomy for cancer","volume":"27","author":"Dj\u00e4rv","year":"2009","journal-title":"J Clin Oncol [Internet]."},{"issue":"1","key":"2026070915093163600_ref23","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1186\/s12957-018-1330-9","article-title":"The change of health-related quality of life after minimally invasive esophagectomy for esophageal cancer: a meta-analysis","volume":"16","author":"Zhang","year":"2018","journal-title":"World J Surg Oncol [Internet]"},{"issue":"10","key":"2026070915093163600_ref24","doi-asserted-by":"publisher","first-page":"2077","DOI":"10.1007\/s00432-017-2451-1","article-title":"A novel systemic immune-inflammation index predicts survival and quality of life of patients after curative resection for esophageal squamous cell carcinoma","volume":"143","author":"Wang","year":"2017","journal-title":"J Cancer Res Clin Oncol [Internet]"},{"key":"2026070915093163600_ref25","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.ijsu.2020.09.049","article-title":"Highlighting sarcopenia management for promoting surgical outcomes in esophageal cancers: evidence from a prospective cohort study","volume":"83","author":"Wang","year":"2020","journal-title":"Int J Surg [Internet]"},{"issue":"7","key":"2026070915093163600_ref26","doi-asserted-by":"publisher","first-page":"1657","DOI":"10.1007\/s11605-020-04783-4","article-title":"Long-term quality of life following transthoracic and transhiatal esophagectomy for esophageal cancer","volume":"25","author":"Jezerskyte","year":"2021","journal-title":"J Gastrointest Surg [Internet]."},{"issue":"11","key":"2026070915093163600_ref27","doi-asserted-by":"publisher","DOI":"10.1093\/dote\/doaa022","article-title":"Long-term health-related quality of life after McKeown and Ivor Lewis esophagectomy for esophageal carcinoma","volume":"33","author":"Jezerskyte","year":"2020","journal-title":"Dis Esophagus [Internet]"},{"issue":"3","key":"2026070915093163600_ref28","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1007\/s11605-012-2069-1","article-title":"Health-related quality of life in patients with oesophageal cancer: analysis at different steps of the treatment pathway","volume":"17","author":"Scarpa","year":"2013","journal-title":"J Gastrointest Surg [Internet]"},{"issue":"1","key":"2026070915093163600_ref29","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1097\/NCC.0b013e318277dc53","article-title":"Factors relating to quality of life after esophagectomy for cancer patients in Taiwan","volume":"37","author":"Chang","year":"2014","journal-title":"Cancer Nurs [Internet]"},{"issue":"103418","key":"2026070915093163600_ref30","doi-asserted-by":"publisher","first-page":"103418","DOI":"10.1016\/j.ijnurstu.2019.103418","article-title":"The effectiveness of a nurse-led exercise and health education informatics program on exercise capacity and quality of life among cancer survivors after esophagectomy: a randomized controlled trial","volume":"101","author":"Chang","year":"2020","journal-title":"Int J Nurs Stud [Internet]"},{"issue":"5","key":"2026070915093163600_ref31","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1093\/jnci\/85.5.365","article-title":"The European Organization for Research and Treatment of cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology","volume":"85","author":"Aaronson","year":"1993","journal-title":"J Natl Cancer Inst [Internet]"},{"issue":"11","key":"2026070915093163600_ref32","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1016\/0959-8049(96)00199-2","article-title":"Development of an EORTC questionnaire module to be used in quality of life assessment for patients with oesophageal cancer. The EORTC quality of life study group","volume":"32A","author":"Blazeby","year":"1996","journal-title":"Eur J Cancer [Internet]"},{"issue":"1","key":"2026070915093163600_ref33","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1186\/1477-7525-4-79","article-title":"Department of Health and Human Services FDA Center for devices and radiological health. Guidance for industry: patient-reported outcome measures: use in medical product development to support labeling claims: draft guidance","volume":"4","author":"U.S. Department of Health and Human Services FDA Center for Drug Evaluation and Research, U.S. Department of Health and Human Services FDA Center for Biologics Evaluation and Research, U.S","year":"2006","journal-title":"Health Qual Life Outcomes [Internet]"},{"issue":"2","key":"2026070915093163600_ref34","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1007\/s00268-018-4786-4","article-title":"Guidelines for perioperative care in esophagectomy: enhanced recovery after surgery (ERAS\u00ae) society recommendations","volume":"43","author":"Low","year":"2019","journal-title":"World J Surg [Internet]"},{"issue":"41","key":"2026070915093163600_ref35","doi-asserted-by":"publisher","first-page":"15423","DOI":"10.3748\/wjg.v20.i41.15423","article-title":"Safety of fast-track rehabilitation after gastrointestinal surgery: systematic review and meta-analysis","volume":"20","author":"Wang","year":"2014","journal-title":"World J Gastroenterol [Internet]"},{"issue":"6","key":"2026070915093163600_ref36","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.1007\/s12328-020-01237-x","article-title":"Epidemiology of esophageal cancer: update in global trends, etiology and risk factors","volume":"13","author":"Uhlenhopp","year":"2020","journal-title":"Clin J Gastroenterol [Internet]"},{"issue":"4","key":"2026070915093163600_ref37","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1007\/s10120-022-01309-6","article-title":"Systematic review of health-related quality of life (HRQoL) issues associated with gastric cancer: capturing cross-cultural differences","volume":"25","author":"Rowsell","year":"2022","journal-title":"Gastric Cancer [Internet]"},{"issue":"7","key":"2026070915093163600_ref38","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1111\/dote.12405","article-title":"Systematic review of patient-reported outcome measures in the surgical treatment of patients with esophageal cancer: PROMs in esophagectomy for cancer","volume":"29","author":"Straatman","year":"2016","journal-title":"Dis Esophagus [Internet]"},{"issue":"3","key":"2026070915093163600_ref39","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1200\/JCO.1993.11.3.570","article-title":"The functional assessment of cancer therapy scale: development and validation of the general measure","volume":"11","author":"Cella","year":"1993","journal-title":"J Clin Oncol [Internet]"},{"issue":"6","key":"2026070915093163600_ref40","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","article-title":"The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection","volume":"30","author":"Ware","year":"1992","journal-title":"Med Care [Internet]"},{"issue":"2","key":"2026070915093163600_ref41","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1245\/s10434-017-6294-4","article-title":"Impact of sarcopenia on unplanned readmission and survival after esophagectomy in patients with Esophageal cancer","volume":"25","author":"Makiura","year":"2018","journal-title":"Ann Surg Oncol [Internet]"},{"issue":"1","key":"2026070915093163600_ref42","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1186\/s12893-023-02149-6","article-title":"The impact of sarcopenia on esophagectomy for cancer: a systematic review and meta-analysis","volume":"23","author":"Park","year":"2023","journal-title":"BMC Surg [Internet]"},{"issue":"6","key":"2026070915093163600_ref43","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1016\/j.gassur.2024.03.001","article-title":"Sarcopenia impacts perioperative and survival outcomes after esophagectomy for cancer: a multicenter study","volume":"28","author":"Park","year":"2024","journal-title":"J Gastrointest Surg [Internet]."},{"issue":"5","key":"2026070915093163600_ref44","doi-asserted-by":"publisher","first-page":"822","DOI":"10.1097\/SLA.0000000000002398","article-title":"Sarcopenia: prevalence, and impact on operative and oncologic outcomes in the multimodal Management of Locally Advanced Esophageal Cancer","volume":"266","author":"Elliott","year":"2017","journal-title":"Ann Surg [Internet]."},{"issue":"3","key":"2026070915093163600_ref45","doi-asserted-by":"publisher","first-page":"1839","DOI":"10.1245\/s10434-021-11002-0","article-title":"Multimodal Prehabilitation during neoadjuvant therapy prior to esophagogastric cancer resection: effect on cardiopulmonary exercise test performance, muscle mass and quality of life-a pilot randomized clinical trial","volume":"29","author":"Allen","year":"2022","journal-title":"Ann Surg Oncol [Internet]"},{"issue":"10","key":"2026070915093163600_ref46","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1634\/theoncologist.2015-0178","article-title":"A walk-and-eat intervention improves outcomes for patients with Esophageal cancer undergoing neoadjuvant chemoradiotherapy","volume":"20","author":"Xu","year":"2015","journal-title":"Oncologist [Internet]"},{"issue":"ezaf271","key":"2026070915093163600_ref47","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezaf271\/8221936","article-title":"Sex differences in health-related quality of life following pulmonary resection: a systematic review","author":"Beushausen","year":"2025","journal-title":"Eur J Cardiothorac Surg [Internet]"},{"issue":"3","key":"2026070915093163600_ref48","doi-asserted-by":"publisher","first-page":"287","DOI":"10.3109\/13682820902994218","article-title":"Gender differences in health-related quality of life following total laryngectomy","volume":"45","author":"Lee","year":"2010","journal-title":"Int J Lang Commun Disord [Internet]"},{"issue":"1","key":"2026070915093163600_ref49","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1097\/SLE.0000000000000842","article-title":"Perioperative outcomes of minimally invasive esophagectomy versus open esophagectomy: a meta-analysis of randomized controlled trials","volume":"31","author":"Memon","year":"2020","journal-title":"Surg Laparosc Endosc Percutan Tech [Internet]"},{"issue":"3","key":"2026070915093163600_ref50","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1007\/s11605-011-1792-3","article-title":"Does minimally invasive esophagectomy (MIE) provide for comparable oncologic outcomes to open techniques? A systematic review","volume":"16","author":"Dantoc","year":"2012","journal-title":"J Gastrointest Surg [Internet]"},{"issue":"12","key":"2026070915093163600_ref51","doi-asserted-by":"publisher","DOI":"10.1093\/dote\/doab008","article-title":"Decrease of physical fitness during neoadjuvant chemoradiotherapy predicts the risk of pneumonia after esophagectomy","volume":"34","author":"Bor","year":"2021","journal-title":"Dis Esophagus [Internet]"},{"issue":"3","key":"2026070915093163600_ref52","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1159\/000050125","article-title":"Preoperative adjuvant radiochemotherapy may increase the risk in patients undergoing thoracoabdominal esophageal resections","volume":"18","author":"Liedman","year":"2001","journal-title":"Dig Surg [Internet]"},{"issue":"5","key":"2026070915093163600_ref53","doi-asserted-by":"publisher","first-page":"1569","DOI":"10.1007\/s00520-017-3993-0","article-title":"Sarcopenia during neoadjuvant therapy for oesophageal cancer: characterising the impact on muscle strength and physical performance","volume":"26","author":"Guinan","year":"2018","journal-title":"Support Care Cancer [Internet]"},{"issue":"8","key":"2026070915093163600_ref54","doi-asserted-by":"publisher","first-page":"2315","DOI":"10.31557\/APJCP.2020.21.8.2315","article-title":"Nutritional status in patients with esophageal cancer receiving chemoradiation and assessing the efficacy of usual care for nutritional managements","volume":"21","author":"Movahed","year":"2020","journal-title":"Asian Pac J Cancer Prev [Internet]"},{"key":"2026070915093163600_ref55","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.ijsu.2018.03.030","article-title":"Neoadjuvant therapy reduces cardiopulmunary function in patients undegoing oesophagectomy","volume":"53","author":"Thomson","year":"2018","journal-title":"Int J Surg [Internet]"},{"issue":"6","key":"2026070915093163600_ref56","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1016\/j.jgo.2019.02.010","article-title":"Predictive value of each geriatric assessment domain for older patients with cancer: a systematic review","volume":"10","author":"Bruijnen","year":"2019","journal-title":"J Geriatr Oncol [Internet]"},{"issue":"3","key":"2026070915093163600_ref57","doi-asserted-by":"publisher","first-page":"e53","DOI":"10.1016\/j.prro.2015.10.015","article-title":"Pulmonary function and cardiac stress test after multimodality treatment of esophageal cancer","volume":"6","author":"D\u00f6beln","year":"2016","journal-title":"Pract Radiat Oncol [Internet]"},{"issue":"7","key":"2026070915093163600_ref58","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1080\/17474124.2017.1325320","article-title":"Nutrition in peri-operative esophageal cancer management","volume":"11","author":"Steenhagen","year":"2017","journal-title":"Expert Rev Gastroenterol Hepatol [Internet]"},{"issue":"5","key":"2026070915093163600_ref59","doi-asserted-by":"publisher","first-page":"3148","DOI":"10.1245\/s10434-021-11122-7","article-title":"Physiotherapy regimens in esophagectomy and gastrectomy: a systematic review and meta-analysis","volume":"29","author":"Tukanova","year":"2022","journal-title":"Ann Surg Oncol [Internet]."},{"issue":"Suppl 5","key":"2026070915093163600_ref60","doi-asserted-by":"publisher","first-page":"S654","DOI":"10.21037\/jtd.2019.02.34","article-title":"Psychological support of esophageal cancer patient?","volume":"11","author":"Pinto","year":"2019","journal-title":"J Thorac Dis [Internet]"},{"issue":"7","key":"2026070915093163600_ref61","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1093\/bjs\/znab078","article-title":"Supervised exercise after oesophageal cancer surgery: the PERFECT multicentre randomized clinical trial","volume":"108","author":"Vulpen","year":"2021","journal-title":"Br J Surg [Internet]"}],"container-title":["Diseases of the Esophagus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/dote\/article-pdf\/39\/4\/doag071\/68740964\/doag071.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/dote\/article-pdf\/39\/4\/doag071\/68740964\/doag071.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T19:09:40Z","timestamp":1783624180000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/dote\/article\/doi\/10.1093\/dote\/doag071\/8729337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,2]]},"references-count":61,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,7,2]]}},"URL":"https:\/\/doi.org\/10.1093\/dote\/doag071","relation":{},"ISSN":["1120-8694","1442-2050"],"issn-type":[{"value":"1120-8694","type":"print"},{"value":"1442-2050","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,8]]},"published":{"date-parts":[[2026,7,2]]},"article-number":"doag071"}}