{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T02:09:18Z","timestamp":1785550158635,"version":"3.56.0"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2018,12,17]],"date-time":"2018-12-17T00:00:00Z","timestamp":1545004800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,6,1]]},"DOI":"10.1093\/dote\/doy112","type":"journal-article","created":{"date-parts":[[2019,6,12]],"date-time":"2019-06-12T16:41:02Z","timestamp":1560357662000},"source":"Crossref","is-referenced-by-count":18,"title":["Intraoperative pyloric botulinum toxin injection during Ivor\u2013Lewis gastroesophagectomy to prevent delayed gastric emptying"],"prefix":"10.1093","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1796-9347","authenticated-orcid":false,"given":"J C","family":"Tham","sequence":"first","affiliation":[{"name":"Peninsula Oesophago-gastric Centre, University Hospitals Plymouth NHS Trust, united Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Nixon","sequence":"additional","affiliation":[{"name":"Peninsula Oesophago-gastric Centre, University Hospitals Plymouth NHS Trust, united Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A V","family":"Ariyarathenam","sequence":"additional","affiliation":[{"name":"Peninsula Oesophago-gastric Centre, University Hospitals Plymouth NHS Trust, united Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Humphreys","sequence":"additional","affiliation":[{"name":"Peninsula Oesophago-gastric Centre, University Hospitals Plymouth NHS Trust, united Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Berrisford","sequence":"additional","affiliation":[{"name":"Peninsula Oesophago-gastric Centre, University Hospitals Plymouth NHS Trust, united Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Wheatley","sequence":"additional","affiliation":[{"name":"Peninsula Oesophago-gastric Centre, University Hospitals Plymouth NHS Trust, united Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Sanders","sequence":"additional","affiliation":[{"name":"Peninsula Oesophago-gastric Centre, University Hospitals Plymouth NHS Trust, united Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,12,17]]},"reference":[{"key":"2019061212395610400_bib1","author":"Varagunam","year":"2017"},{"key":"2019061212395610400_bib2","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1016\/j.athoracsur.2014.06.057","article-title":"Surgical techniques to prevent delayed gastric emptying after esophagectomy with gastric interposition: a systematic review","volume":"98","author":"Akkerman","year":"2014","journal-title":"Ann Thorac Surg"},{"key":"2019061212395610400_bib3","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.athoracsur.2010.12.055","article-title":"Management of delayed gastric emptying after esophagectomy with endoscopic balloon dilatation of the pylorus","volume":"91","author":"Lanuti","year":"2011","journal-title":"Ann Thorac Surg"},{"key":"2019061212395610400_bib4","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/dote.12191","article-title":"The impact of pyloric drainage on clinical outcome following esophagectomy: a systematic review","volume":"28","author":"Arya","year":"2015","journal-title":"Dis Esophagus"},{"key":"2019061212395610400_bib5","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1016\/j.athoracsur.2014.02.046","article-title":"Comparison of pyloric intervention strategies at the time of esophagectomy: Is more better?","volume":"97","author":"Antonoff","year":"2014","journal-title":"Ann Thorac Surg"},{"key":"2019061212395610400_bib6","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/jso.24084","article-title":"Functional outcome after Ivor\u2013Lewis esophagectomy for cancer","volume":"113","author":"Deldycke","year":"2016","journal-title":"J Surg Oncol"},{"key":"2019061212395610400_bib7","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1089\/lap.2015.0575","article-title":"Intraoperative endoscopic botox injection during total esophagectomy prevents the need for pyloromyotomy or dilatation","volume":"26","author":"Fuchs","year":"2016","journal-title":"J Laparoendosc Adv Surg Tech A"},{"key":"2019061212395610400_bib8","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1177\/000313481007601026","article-title":"Outcomes of minimally invasive esophagectomy without pyloroplasty: analysis of 109 cases","volume":"76","author":"Nguyen","year":"2010","journal-title":"Am Surg"},{"key":"2019061212395610400_bib9","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1159\/000064206","article-title":"Pyloric drainage (pyloroplasty) or no drainage in gastric reconstruction after esophagectomy: a meta-analysis of randomized controlled trials","volume":"19","author":"Urschel","year":"2002","journal-title":"Dig Surg"},{"key":"2019061212395610400_bib10","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.jtcvs.2008.08.049","article-title":"Is botulinum toxin injection of the pylorus during Ivor\u2013Lewis esophagogastrectomy the optimal drainage strategy?","volume":"137","author":"Cerfolio","year":"2009","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2019061212395610400_bib11","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1016\/j.athoracsur.2013.11.026","article-title":"Intrapyloric botulinum injection increases postoperative esophagectomy complications","volume":"97","author":"Eldaif","year":"2014","journal-title":"Ann Thorac Surg"},{"key":"2019061212395610400_bib12","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1111\/dote.12035","article-title":"Should we continue to drain the pylorus in patients undergoing an esophagectomy?","volume":"27","author":"Gaur","year":"2014","journal-title":"Dis Esophagus"},{"key":"2019061212395610400_bib13","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1510\/icvts.2006.149500","article-title":"Does pyloroplasty following esophagectomy improve early clinical outcomes?","volume":"6","author":"Khan","year":"2007","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"2019061212395610400_bib14","doi-asserted-by":"crossref","first-page":"A281.2","DOI":"10.1136\/gutjnl-2015-309861.605","article-title":"PWE-157 Reducing anastomotic leak rate in Ivor Lewis oesophagectomy\u2014testing a change from mechanical to semi-mechanical anastomosis","volume":"64","author":"Clark","year":"2015","journal-title":"Gut"},{"key":"2019061212395610400_bib15","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.ijsu.2014.01.015","article-title":"The implementation and effectiveness of an enhanced recovery programme after oesophago-gastrectomy: a prospective cohort study","volume":"12","author":"Ford","year":"2014","journal-title":"Int J Surg"},{"key":"2019061212395610400_bib16","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1016\/j.athoracsur.2009.01.075","article-title":"Prevention of delayed gastric emptying after esophagectomy: a single center's experience with botulinum toxin","volume":"87","author":"Martin","year":"2009","journal-title":"Ann Thorac Surg"},{"key":"2019061212395610400_bib17","article-title":"Benchmarking complications associated with esophagectomy","volume":"1","author":"Low","year":"2017","journal-title":"Ann Surg"},{"key":"2019061212395610400_bib18","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1097\/SLA.0b013e3181afde41","article-title":"The accordion severity grading system of surgical complications","volume":"250","author":"Strasberg","year":"2009","journal-title":"Ann Surg"},{"key":"2019061212395610400_bib19","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1111\/apt.13053","article-title":"Impaired fasting pyloric compliance in gastroparesis and the therapeutic response to pyloric dilatation","volume":"41","author":"Gourcerol","year":"2015","journal-title":"Aliment Pharmacol Ther"},{"key":"2019061212395610400_bib20","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.3748\/wjg.v11.i8.1172","article-title":"Synchronous electrogastrographic and manometric study of the stomach as an esophageal substitute","volume":"11","author":"Izb\u00e9ki","year":"2005","journal-title":"World J Gastroenterol"},{"key":"2019061212395610400_bib21","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1097\/SLA.0000000000001465","article-title":"Gut hormone suppression increases food intake after esophagectomy with gastric conduit reconstruction","volume":"262","author":"Elliott","year":"2015","journal-title":"Ann Surg"},{"key":"2019061212395610400_bib22","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1097\/SLA.0000000000001918","article-title":"Weight loss, satiety, and the postprandial gut hormone response after esophagectomy","volume":"266","author":"Elliott","year":"2017","journal-title":"Ann Surg"},{"key":"2019061212395610400_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/dote\/dox006","article-title":"Diabetes mellitus and risk of anastomotic leakage after esophagectomy: a systematic review and meta-analysis","volume":"30","author":"Li","year":"2017","journal-title":"Dis Esophagus"},{"key":"2019061212395610400_bib24","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/S1470-2045(15)00040-6","article-title":"Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): long-term results of a randomised controlled trial","volume":"16","author":"Shapiro","year":"2015","journal-title":"Lancet Oncol"}],"container-title":["Diseases of the Esophagus"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/dote\/article-pdf\/32\/6\/doy112\/28797352\/doy112.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,5]],"date-time":"2021-01-05T20:44:38Z","timestamp":1609879478000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/dote\/article\/doi\/10.1093\/dote\/doy112\/5250777"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,17]]},"references-count":24,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2018,12,17]]},"published-print":{"date-parts":[[2019,6,1]]}},"URL":"https:\/\/doi.org\/10.1093\/dote\/doy112","relation":{},"ISSN":["1120-8694","1442-2050"],"issn-type":[{"value":"1120-8694","type":"print"},{"value":"1442-2050","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,6]]},"published":{"date-parts":[[2018,12,17]]},"article-number":"doy112"}}