{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T15:42:08Z","timestamp":1768923728062,"version":"3.49.0"},"reference-count":0,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:p>To discuss challenges concerning treatment for chronic prostatitis\/chronic pelvic pain syndrome (CP\/CPPS) and review complementary and alternative medical (CAM) therapies being evaluated for this condition, we performed a comprehensive search of articles published from 1990\u20132005 using the PubMed, Medline databases.  Data from the articles were abstracted and pooled by subject.  Keywords cross\u2010searched with CP\/CPPS included: complementary, alternative, integrative, therapies, interventions, nutrition, antioxidants, herbs, supplements, biofeedback and acupuncture.  Listed articles with no abstracts were not included.  Various CAM therapies for CP\/CPPS exist including biofeedback, acupuncture, hyperthermia and electrostimulation.  Additionally, a variety of <jats:italic>in vitro<\/jats:italic> and <jats:italic>in vivo<\/jats:italic> studies testing herbal and nutritional supplements were found.  Saw palmetto, cernilton and quercetin were the most frequently tested supplements for CP\/CPP Although many CAM therapies demonstrate positive preliminary observations as prospective treatments for CP\/CPPS, further exploratory studies including more randomized, controlled trials are necessary for significant validation as treatment options for this complex disorder.<\/jats:p>","DOI":"10.1093\/ecam\/neh128","type":"journal-article","created":{"date-parts":[[2005,10,11]],"date-time":"2005-10-11T00:13:49Z","timestamp":1128989629000},"page":"495-501","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Complementary and Alternative Medicine for Chronic Prostatitis\/Chronic Pelvic Pain Syndrome"],"prefix":"10.1155","volume":"2","author":[{"given":"Jillian L.","family":"Capodice","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debra L.","family":"Bemis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph","family":"Buttyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven A.","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron E.","family":"Katz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,9,12]]},"container-title":["Evidence-Based Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2005\/649274.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1093\/ecam\/neh128","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T15:26:46Z","timestamp":1723130806000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1093\/ecam\/neh128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["10.1093\/ecam\/neh128"],"URL":"https:\/\/doi.org\/10.1093\/ecam\/neh128","archive":["Portico"],"relation":{},"ISSN":["1741-427X","1741-4288"],"issn-type":[{"value":"1741-427X","type":"print"},{"value":"1741-4288","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,1]]},"assertion":[{"value":"2005-04-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2005-09-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2005-09-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}