{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T13:10:56Z","timestamp":1772889056878,"version":"3.50.1"},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2009,1]]},"abstract":"<jats:p>We examined how acupuncture affected the blood flow of muscle, kidney, stomach, small intestine, brain, lung, heart, spleen and liver. Wistar rats anesthetized with urethane (<jats:italic>n<\/jats:italic> = 27) were allocated into the control (<jats:italic>n<\/jats:italic> = 10), ST\u20107 (Hsia\u2010Kuan, <jats:italic>n<\/jats:italic> = 10) and LI\u20104 (Hoku, <jats:italic>n<\/jats:italic> = 7) groups. To measure organ blood flow, colored microspheres (CMS) were injected through a catheter positioned in the left ventricle and blood samples were drawn from the femoral artery. Yellow CMS (3.6\u20134.2 \u00d7 10<jats:sup>5<\/jats:sup>) and blue CMS (6.0\u20136.9 \u00d7 10<jats:sup>5<\/jats:sup>) were injected at intervals of about 30 min. An acupuncture needle (\u03c6 340 \u03bcm) was inserted into the left ST\u20107 point (left masseter muscle) or the right LI\u20104 point after the first sampling and left for about 30 min (10 twists at 1 Hz, 2\u2010min intervals). The mean blood flow of nine organs varied widely from 4.03 to 0.20 (ml\/min\/g). Acupuncture to the ST\u20107 produced significant changes of the blood flow (percentage change from baseline) in the muscle, kidney, brain and heart (<jats:italic>P<\/jats:italic> &lt; 0.05, versus control), but those of LI\u20104 were not significant. The blood flow of the left masseter muscle after acupuncture to ST\u20107 (left masseter muscle) tended to increase (<jats:italic>P<\/jats:italic> = 0.08). Changes in blood pressure during the experimental periods were almost similar among these three groups. Acupuncture stimulation increases the blood flow of several organs by modulating the central circulatory systems, and the effects differed with sites of stimulation.<\/jats:p>","DOI":"10.1093\/ecam\/nem068","type":"journal-article","created":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:25:25Z","timestamp":1183249525000},"page":"77-83","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Acupuncture on the Blood Flow of Various Organs Measured Simultaneously by Colored Microspheres in Rats"],"prefix":"10.1155","volume":"6","author":[{"given":"Hiroyuki","family":"Tsuru","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Kawakita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,4,12]]},"container-title":["Evidence-Based Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2009\/760269.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1093\/ecam\/nem068","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T15:22:41Z","timestamp":1723130561000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1093\/ecam\/nem068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4,12]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["10.1093\/ecam\/nem068"],"URL":"https:\/\/doi.org\/10.1093\/ecam\/nem068","archive":["Portico"],"relation":{},"ISSN":["1741-427X","1741-4288"],"issn-type":[{"value":"1741-427X","type":"print"},{"value":"1741-4288","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,4,12]]},"assertion":[{"value":"2006-09-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2007-04-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2007-04-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}