{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:35:22Z","timestamp":1790699722054,"version":"4.1.0"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,6,23]],"date-time":"2011-06-23T00:00:00Z","timestamp":1308787200000},"content-version":"vor","delay-in-days":173,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2011,1]]},"abstract":"\n The objective of this study was to assess the evidence for or against the effectiveness of cupping as a treatment option for pain. Fourteen databases were searched. Randomized clinical trials (RCTs) testing cupping in patients with pain of any origin were considered. Trials using cupping with or without drawing blood were included, while trials comparing cupping with other treatments of unproven efficacy were excluded. Trials with cupping as concomitant treatment together with other treatments of unproven efficacy were excluded. Trials were also excluded if pain was not a central symptom of the condition. The selection of studies, data extraction and validation were performed independently by three reviewers. Seven RCTs met all the inclusion criteria. Two RCTs suggested significant pain reduction for cupping in low back pain compared with usual care (\n P<\/jats:italic>\n < .01) and analgesia (\n P<\/jats:italic>\n < .001). Another two RCTs also showed positive effects of cupping in cancer pain (\n P<\/jats:italic>\n < .05) and trigeminal neuralgia (\n P<\/jats:italic>\n < .01) compared with anticancer drugs and analgesics, respectively. Two RCTs reported favorable effects of cupping on pain in brachialgia compared with usual care (\n P<\/jats:italic>\n = .03) or heat pad (\n P<\/jats:italic>\n < .001). The other RCT failed to show superior effects of cupping on pain in herpes zoster compared with anti\u2010viral medication (\n P<\/jats:italic>\n = .065). Currently there are few RCTs testing the effectiveness of cupping in the management of pain. Most of the existing trials are of poor quality. Therefore, more rigorous studies are required before the effectiveness of cupping for the treatment of pain can be determined.\n <\/jats:p>","DOI":"10.1093\/ecam\/nep035","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T20:45:04Z","timestamp":1241729104000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":95,"title":["Cupping for Treating Pain: A Systematic Review"],"prefix":"10.1155","volume":"2011","author":[{"given":"Jong-In","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myeong Soo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Hyo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Boddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edzard","family":"Ernst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,6,23]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.279.19.1548"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/1472\u20106882\u20107\u201015"},{"key":"e_1_2_6_3_2","volume-title":"Cupping Therapy","author":"Chirali I. Z.","year":"2007"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20104632.2004.02224.x"},{"key":"e_1_2_6_5_2","first-page":"789","article-title":"Systematic review of cupping including bloodletting therapy for musculoskeletal diseases in Korea","volume":"21","author":"Kwon Y. D.","year":"2007","journal-title":"Korean Journal of Oriental Physiology & Pathology"},{"key":"e_1_2_6_6_2","first-page":"187","volume-title":"Cochrane Handbook for Systematic Reviews of Interventions","author":"Julian P. T. H.","year":"2008"},{"key":"e_1_2_6_7_2","first-page":"14","article-title":"Observations on the efficacy of cupping for treating 30 patients with cancer pain","volume":"25","author":"Huang Z. F.","year":"2006","journal-title":"Shanghai Journal of Acupuncture and Moxibustion"},{"key":"e_1_2_6_8_2","first-page":"340","article-title":"The effect of moving cupping therapy on non-specific low back pain","volume":"21","author":"Hong Y. F.","year":"2006","journal-title":"Chinese Journal of Rehabilitation Medicine"},{"key":"e_1_2_6_9_2","first-page":"272","article-title":"Observation on therapeutic effects of blood-letting puncture with cupping in acute trigeminal neuralgia","volume":"17","author":"Zhang Z.","year":"1997","journal-title":"Journal of Traditional Chinese Medicine"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctim.2008.05.003"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctim.2006.07.004"},{"key":"e_1_2_6_12_2","article-title":"Effectiveness of cupping therapy in brachialgia paraestetica nocturna: results of a randomized controlled trial","volume":"14","author":"Michalsen A.","year":"2007","journal-title":"Forsch Komplementarmed"},{"key":"e_1_2_6_13_2","first-page":"23","article-title":"Therapeutic effect of aciclovir combination with callateral-puncturing and cupping in the treatment of 40 cases of herpes zoster","volume":"16","author":"Xu L.","year":"2004","journal-title":"Tianjin Pharmacy"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/med\/9780198566045.001.0001"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.4103\/0022\u20103859.41806"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.316.7124.61"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/385480c0"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0197\u20102456(97)00150\u20105"}],"container-title":["Evidence-Based Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2011\/467014.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2011\/467014.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1093\/ecam\/nep035","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T15:55:14Z","timestamp":1718121314000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1093\/ecam\/nep035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["10.1093\/ecam\/nep035"],"URL":"https:\/\/doi.org\/10.1093\/ecam\/nep035","archive":["Portico"],"relation":{},"ISSN":["1741-427X","1741-4288"],"issn-type":[{"value":"1741-427X","type":"print"},{"value":"1741-4288","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1]]},"assertion":[{"value":"2008-11-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-04-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-06-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"467014"}}