{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T18:27:14Z","timestamp":1793212034996,"version":"4.5.0"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T00:00:00Z","timestamp":1589673600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,12,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Backgrounds and Aims<\/jats:title>\n                  <jats:p>We aimed to evaluate the safety of Bacille Calmette\u2013Gu\u00e9rin [BCG] vaccination in infants born to mothers receiving anti-tumour necrosis factor [anti-TNF] therapy for inflammatory bowel disease.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Adverse events of BCG vaccination were evaluated in 90 infants who were last exposed to anti-TNF agents at a median of gestational week 30.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>After receiving BCG vaccination at a median age of 6 months [range, 0.25\u201311 months], three infants [3.3%] showed injection site swelling, two of whom also showed axillar lymphadenopathy. The rates of adverse events were similar between infants who were last exposed to anti-TNF agents before the third trimester [n\u2005=\u200535] and those who were last exposed in the third trimester [n\u2005=\u200555] [2.9% vs 3.6%; p\u2005=\u20051.00]. All adverse events were spontaneously resolved and there were no serious adverse events such as active tuberculosis infection or death.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>BCG vaccination after 6 months of age is of low risk in infants exposed to anti-TNF agents in utero.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ecco-jcc\/jjaa099","type":"journal-article","created":{"date-parts":[[2020,5,12]],"date-time":"2020-05-12T13:08:13Z","timestamp":1589288893000},"page":"1780-1784","source":"Crossref","is-referenced-by-count":29,"title":["Safety and Optimal Timing of BCG Vaccination in Infants Born to Mothers Receiving Anti-TNF Therapy for Inflammatory Bowel Disease"],"prefix":"10.1093","volume":"14","author":[{"given":"Sang Hyoung","family":"Park","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyo Jong","family":"Kim","sequence":"additional","affiliation":[{"name":"Center for Crohn\u2019s and Colitis, Department of Gastroenterology, Kyung Hee University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Kyun","family":"Lee","sequence":"additional","affiliation":[{"name":"Center for Crohn\u2019s and Colitis, Department of Gastroenterology, Kyung Hee University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Mi","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Bum","family":"Kang","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Daejeon St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Daejeon, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung Ik","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyeong Ok","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoo Jin","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun Jin","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Daegu Fatima Hospital, Daegu, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo-Kyung","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Il","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6647-6325","authenticated-orcid":false,"given":"Byong Duk","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Ae","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suk-Kyun","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 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