{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T08:14:09Z","timestamp":1793434449621,"version":"4.5.0"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T00:00:00Z","timestamp":1680048000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100006483","name":"Abbvie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,20]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Fatigue is commonly reported by patients with inflammatory bowel disease [IBD], but the determinants of IBD-related fatigue have yet to be determined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To identify the factors associated with fatigue in a large population of patients with IBD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>Fatigue and nine other IBD-related disability dimensions were assessed in a cohort of 1704 consecutive patients with IBD using the IBD-disk questionnaire in a cross-sectional survey of 42 French and Belgian centres. Fatigue and severe fatigue were defined as energy subscores &amp;gt;5 and &amp;gt;7, respectively. Determinants of fatigue were assessed using univariate and multivariate analyses (odds ratios [ORs] are provided with 95% confidence intervals).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The prevalence rates of fatigue and severe fatigue were 54.1% and 37.1%, respectively. Both fatigue and severe fatigue were significantly higher in patients with active disease than in patients with inactive disease [64.9% vs 44.7% and 47.4% vs 28.6%, respectively; p\u2005&amp;lt;\u20050.001 for both comparisons]. In the multivariate analysis stratified by age, sex, type of IBD and IBD activity, fatigue was associated with age &amp;gt;40 years (OR\u2005=\u20050.71 [0.54\u20130.93]), female sex (OR\u2005=\u20051.48 [1.13\u20131.93]) and IBD-related sick leave (OR\u2005=\u20051.61 [1.19\u20132.16]), and joint pain (OR\u2005=\u20051.60 [1.17\u20132.18]), abdominal pain (OR\u2005=\u20051.78 [1.29\u20132.45]), regulating defecation (OR\u2005=\u20051.67 [1.20\u20132.32]), education and work (OR\u2005=\u20051.96 [1.40\u20132.75]), body image (OR\u2005=\u20051.38 [1.02\u20131.86]), sleep (OR\u2005=\u20053.60 [2.66\u20134.88]) and emotions (OR\u2005=\u20053.60 [2.66\u20134.88]) subscores &amp;gt;5.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Determinants of fatigue are not restricted to IBD-related factors but also include social factors, sleep and emotional disturbances, thus supporting a holistic approach to IBD patient care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ecco-jcc\/jjad060","type":"journal-article","created":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T12:23:15Z","timestamp":1680178995000},"page":"1418-1425","source":"Crossref","is-referenced-by-count":20,"title":["Prevalence and Determinants of Fatigue in Patients with IBD: A Cross-Sectional Survey from the GETAID"],"prefix":"10.1093","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6676-1222","authenticated-orcid":false,"given":"Aurelien","family":"Amiot","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Hopitaux Universitaires Bic\u00eatre, AP-HP, Universit\u00e9 Paris Saclay, INSERM, Centre for Research in Epidemiology and Population Health , Le Kremlin Bic\u00eatre , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayma","family":"Chaibi","sequence":"additional","affiliation":[{"name":"Department of 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