{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:18:06Z","timestamp":1787008686515,"version":"build-2736575974"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T00:00:00Z","timestamp":1745539200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and aims<\/jats:title>\n                    <jats:p>New techniques for endoscopic resection, including endoscopic submucosal dissection (ESD), have been developed to allow for en-bloc resection with very low recurrence rates and organ sparing in patients without inflammatory bowel disease (IBD). Data on ESD for the management of colorectal dysplasia in IBD patients are scarce. We aimed to evaluate the efficacy and safety of ESD for the treatment of IBD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective multicenter cohort study that evaluated consecutive ESD procedures in IBD patients with visible dysplasia from 20 French centers with ESD experience. Between June 2008 and March 2022, all IBD patients included in the local ESD databases and who underwent ESD for visible dysplasia proven on biopsy were included. All patients were included from the date ESD was performed, and endoscopic follow-up and surgical data were collected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 88 lesions resected in 82 patients (19 patients with Crohn\u2019s disease), 82% and 80% of patients had R0 and curative resection, respectively. Ten (12%) patients required surgery: 1 for complication, 3 for endoscopic failure, and 6 for noncurative resection. After a median follow-up of 20 (IQR 10.5-45) months, 4 patients experienced local recurrence, and 14 (17%) underwent surgery. Two patients died from cardiovascular issues during the follow-up. Factors associated with local recurrence were R1 resection, associated primary sclerosing cholangitis, a personal history of colorectal cancer, and active lesions at the ESD site.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Endoscopic submucosal dissection is feasible for IBD patients with visible colorectal dysplasia and has an acceptable safety profile. These findings should be evaluated further in control trials.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ecco-jcc\/jjaf057","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T06:46:02Z","timestamp":1745477162000},"source":"Crossref","is-referenced-by-count":6,"title":["Endoscopic submucosal dissection for visible dysplasia in inflammatory bowel disease: a nationwide multicenter cohort from the GETAID and the SFED"],"prefix":"10.1093","volume":"19","author":[{"given":"Sophie","family":"Geyl","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, University Hospital of Limoges Dupuytren , Limoges ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00e9mie","family":"Jacques","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University Hospital of Limoges Dupuytren , Limoges ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Anneraud","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University Hospital of Limoges Dupuytren , Limoges ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislas","family":"Chaussade","sequence":"additional","affiliation":[{"name":"Gastroenterology and Endoscopy Unit, Facult\u00e9 de M\u00e9decine, H\u00f4pital Cochin, Assistance Publique-H\u00f4pitaux de Paris (AP-HP), Universit\u00e9 Paris Descartes , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vered","family":"Abitbol","sequence":"additional","affiliation":[{"name":"Gastroenterology and Endoscopy Unit, Facult\u00e9 de M\u00e9decine, H\u00f4pital Cochin, Assistance Publique-H\u00f4pitaux de Paris (AP-HP), Universit\u00e9 Paris Descartes , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Baptiste","family":"Chevaux","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University Hospital of Nancy , Nancy ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Peyrin-biroulet","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University Hospital of Nancy , Nancy ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Yzet","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Amiens University Hospital, Picardie University , Amiens ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Pioche","sequence":"additional","affiliation":[{"name":"Endoscopy and Gastroenterology Unit, Edouard Herriot Hospital, Hospices civils de Lyon , Lyon ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"Berger","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Centre Medico-chirurgical Magellan, CHU de Bordeaux, H\u00f4pital Haut-L\u00e9v\u00eaque , Bordeaux ,","place":["France"]},{"name":"Universit\u00e9 de Bordeaux , Bordeaux ,","place":["France"]},{"name":"INSERM CIC 1401 , Bordeaux ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Laharie","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Centre Medico-chirurgical Magellan, CHU de Bordeaux, H\u00f4pital Haut-L\u00e9v\u00eaque , Bordeaux ,","place":["France"]},{"name":"Universit\u00e9 de Bordeaux , Bordeaux ,","place":["France"]},{"name":"INSERM CIC 1401 , Bordeaux ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Koch","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and INSERM UMR RIGHT, CHU Besan\u00e7on and Universit\u00e9 de Franche Comt\u00e9 , Besan\u00e7on ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Leblanc","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Unit, Jean Mermoz Clinic , Lyon ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e9lanie","family":"Serrero","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Aix-Marseille Universit\u00e9, APHM, H\u00f4pital Nord , Marseille ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Barthet","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Aix-Marseille Universit\u00e9, APHM, H\u00f4pital Nord , Marseille ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Michel","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Aix-Marseille Universit\u00e9, APHM, H\u00f4pital Nord , Marseille ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timoth\u00e9e","family":"Wallenhorst","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Pontchaillou University Hospital , Rennes ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Bouguen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Pontchaillou University Hospital , Rennes ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marine","family":"Camus","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, AP-HP, H\u00f4pital 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University Paris-Descartes Sorbonne-Paris Cit\u00e9 , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Perrod","sequence":"additional","affiliation":[{"name":"Gastroenterology and Endoscopy Division, H\u00f4pital Europ\u00e9en Georges Pompidou, Assistance Publique - H\u00f4pitaux de Paris, University Paris-Descartes Sorbonne-Paris Cit\u00e9 , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Simon","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Institut Mutualiste Montsouris , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Gerard","sequence":"additional","affiliation":[{"name":"Department of Hepatology and Gastroenterology , Lille ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Stefanescu","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, H\u00f4pital Beaujon, MICI et Assistance Nutritive, APHP , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alban","family":"Benezech","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Henri Duffaut Hospital , Avignon ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffroy","family":"Vanbiervliet","sequence":"additional","affiliation":[{"name":"Department of Digestive Endoscopy, Centre Hospitalier Universitaire de Nice , Nice ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yann L E","family":"Baleur","sequence":"additional","affiliation":[{"name":"Endoscopy and Gastroenterology Unit, Hospital Saint Joseph , Paris 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