{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T03:52:19Z","timestamp":1781841139918,"version":"3.54.5"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and aims<\/jats:title>\n                    <jats:p>Surveillance colonoscopy programmes in inflammatory bowel disease (IBD) are associated with reduced colorectal cancer (CRC) incidence. This study aims to compare the performance of virtual chromoendoscopy (VCE) using linked color imaging (LCI) and dye-chromoendoscopy (DCE) with methylene blue for the detection of colonic neoplastic lesions during surveillance colonoscopy in patients with IBD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single-center retrospective cohort study included patients with colonic IBD undergoing CRC surveillance colonoscopy between June 2018 and December 2024. The primary outcome was the total neoplastic lesions detected in each group. The secondary outcome was the neoplastic lesions detection rate. Propensity-score matching and multivariable Poisson and logistic regression were used to adjust for baseline differences and identify independent predictors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>311 patients were included (112 DCE, 199 LCI). The mean number of neoplastic lesions identified per colonoscopy was 0.116 with DCE and 0.085 with LCI (P\u2009=\u2009.472). Similarly, the neoplasia detection rate was comparable between techniques (8.03% for DCE vs 7.53% for LCI; odds ratio [OR] 1.07, 95% confidence interval [CI], 0.45-2.54, P\u2009=\u2009.874). After 1:1 propensity score matching, the chromoendoscopy modality (DCE vs LCI) was not associated with the total number of neoplastic lesions (IRR 0.77; 95% CI, 0.34-1.78; P\u2009=\u2009.543) and with the neoplastic lesions detection rate (OR 0.58; 95% CI, 0.21-1.65; P\u2009=\u2009.310).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>LCI-based VCE provides a neoplastic yield comparable to traditional DCE in patients with long-standing colonic IBD undergoing surveillance colonoscopy. As with other VCE modalities, LCI may be adopted as an alternative to DCE for dysplasia surveillance in IBD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ecco-jcc\/jjag085","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T11:47:40Z","timestamp":1780487260000},"source":"Crossref","is-referenced-by-count":0,"title":["Virtual chromoendoscopy with linked color imaging versus dye-chromoendoscopy in the surveillance of patients with long-standing colonic inflammatory bowel disease"],"prefix":"10.1093","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7277-1053","authenticated-orcid":false,"given":"Roberto","family":"Gabbiadini","sequence":"first","affiliation":[{"name":"IBD Center, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan 20089,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Franchellucci","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan 20089,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Minini","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan 20089,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan 20072,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8543-4355","authenticated-orcid":false,"given":"Arianna","family":"Dal Buono","sequence":"additional","affiliation":[{"name":"IBD Center, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan 20089,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Privitera","sequence":"additional","affiliation":[{"name":"IBD Center, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan 20089,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan 20072,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Spadaccini","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan 20089,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan 20072,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0198-9144","authenticated-orcid":false,"given":"Giulia","family":"Migliorisi","sequence":"additional","affiliation":[{"name":"IBD Center, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan 20089,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan 20072,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Petronio","sequence":"additional","affiliation":[{"name":"IBD Center, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan 20089,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan 20072,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Farinola","sequence":"additional","affiliation":[{"name":"IBD Center, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan 20089,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan 20072,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Di Martino","sequence":"additional","affiliation":[{"name":"IBD Center, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan 20089,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan 20072,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0076-8549","authenticated-orcid":false,"given":"Cristina","family":"Bezzio","sequence":"additional","affiliation":[{"name":"IBD Center, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan 20089,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan 20072,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesare","family":"Hassan","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan 20089,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan 20072,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Repici","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan 20089,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan 20072,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Armuzzi","sequence":"additional","affiliation":[{"name":"IBD Center, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan 20089,","place":["Italy"]},{"name":"Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan 20072,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,19]]},"reference":[{"key":"2026061823084165400_jjag085-B1","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1056\/NEJMra1403718","article-title":"Cancers complicating inflammatory bowel disease","volume":"372","author":"Beaugerie","year":"2015","journal-title":"N Engl J Med"},{"key":"2026061823084165400_jjag085-B2","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1016\/j.cgh.2012.01.010","article-title":"Risk of colorectal cancer in patients with ulcerative colitis: a meta-analysis of population-based cohort studies","volume":"10","author":"Jess","year":"2012","journal-title":"Clin Gastroenterol Hepatol"},{"key":"2026061823084165400_jjag085-B3","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/S0140-6736(19)32545-0","article-title":"Colorectal cancer in ulcerative colitis: a Scandinavian population-based cohort study","volume":"395","author":"Ol\u00e9n","year":"2020","journal-title":"Lancet"},{"key":"2026061823084165400_jjag085-B4","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1111\/j.1365-2036.2006.02854.x","article-title":"Meta-analysis: colorectal and small bowel cancer risk in patients with Crohn\u2019s disease","volume":"23","author":"Canavan","year":"2006","journal-title":"Aliment Pharmacol Ther"},{"key":"2026061823084165400_jjag085-B5","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/S2468-1253(20)30005-4","article-title":"Colorectal cancer in Crohn\u2019s disease: a Scandinavian population-based cohort study","volume":"5","author":"Ol\u00e9n","year":"2020","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"2026061823084165400_jjag085-B6","doi-asserted-by":"publisher","first-page":"1801","DOI":"10.1038\/s41395-018-0354-7","article-title":"Strategies for detecting colorectal cancer in patients with inflammatory bowel disease: a cochrane systematic review and meta-analysis","volume":"113","author":"Bye","year":"2018","journal-title":"Am J Gastroenterol"},{"key":"2026061823084165400_jjag085-B7","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1093\/ecco-jcc\/jjac187","article-title":"ECCO guidelines on inflammatory bowel disease and malignancies","volume":"17","author":"Gordon","year":"2023","journal-title":"J Crohns Colitis"},{"key":"2026061823084165400_jjag085-B8","doi-asserted-by":"publisher","first-page":"s1","DOI":"10.1136\/gutjnl-2019-318484","article-title":"British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults","volume":"68","author":"Lamb","year":"2019","journal-title":"Gut"},{"key":"2026061823084165400_jjag085-B9","doi-asserted-by":"publisher","first-page":"384","DOI":"10.14309\/ajg.0000000000000152","article-title":"ACG clinical guideline: ulcerative colitis in adults","volume":"114","author":"Rubin","year":"2019","journal-title":"Am J Gastroenterol"},{"key":"2026061823084165400_jjag085-B10","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1136\/gutjnl-2017-315235","article-title":"Advanced endoscopic techniques in the assessment of inflammatory bowel disease: new technology, new era","volume":"68","author":"Iacucci","year":"2019","journal-title":"Gut"},{"key":"2026061823084165400_jjag085-B11","doi-asserted-by":"publisher","first-page":"2128","DOI":"10.1016\/j.cgh.2024.11.008","article-title":"Comparative efficacy and safety of endoscopic modalities for colorectal cancer screening in inflammatory bowel disease: a systematic review and network meta-analysis","volume":"23","author":"Sinopoulou","year":"2025","journal-title":"Clin Gastroenterol Hepatol"},{"key":"2026061823084165400_jjag085-B12","doi-asserted-by":"publisher","first-page":"E974","DOI":"10.1055\/s-0043-117944","article-title":"Perspectives on endoscopic surveillance of dysplasia in inflammatory bowel disease: a survey of academic gastroenterologists","volume":"5","author":"Gallinger","year":"2017","journal-title":"Endosc Int Open"},{"key":"2026061823084165400_jjag085-B13","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1111\/1751-2980.13031","article-title":"Practice pattern variability among gastroenterologists in colorectal cancer surveillance and management of colorectal dysplasia in inflammatory bowel disease","volume":"22","author":"Chan","year":"2021","journal-title":"J Dig Dis"},{"key":"2026061823084165400_jjag085-B14","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1038\/nrgastro.2017.18","article-title":"Advances in image enhancement in colonoscopy for detection of adenomas","volume":"14","author":"Matsuda","year":"2017","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"2026061823084165400_jjag085-B15","doi-asserted-by":"publisher","first-page":"17562848211005692","DOI":"10.1177\/17562848211005692","article-title":"Rediscovering histology: what is new in endoscopy for inflammatory bowel disease?","volume":"14","author":"Solitano","year":"2021","journal-title":"Ther Adv Gastroenterol"},{"key":"2026061823084165400_jjag085-B16","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1093\/ibd\/izaa011","article-title":"Meta-analysis of virtual-based chromoendoscopy compared with dye-spraying chromoendoscopy standard and high-definition white light endoscopy in patients with inflammatory bowel disease at increased risk of colon cancer","volume":"26","author":"El-Dallal","year":"2020","journal-title":"Inflamm Bowel Dis"},{"key":"2026061823084165400_jjag085-B17","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1053\/j.gastro.2021.05.063","article-title":"AGA clinical practice update on endoscopic surveillance and management of colorectal dysplasia in inflammatory bowel diseases: expert review","volume":"161","author":"Murthy","year":"2021","journal-title":"Gastroenterology"},{"key":"2026061823084165400_jjag085-B18","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1055\/a-1031-7657","article-title":"Advanced imaging for detection and differentiation of colorectal neoplasia: European Society of Gastrointestinal Endoscopy (ESGE) Guideline\u2014Update 2019","volume":"51","author":"Bisschops","year":"2019","journal-title":"Endoscopy"},{"key":"2026061823084165400_jjag085-B19","doi-asserted-by":"publisher","first-page":"136","DOI":"10.17235\/reed.2025.9878\/2023","article-title":"Virtual chromoendoscopy for the identification of colonic dysplasia in patients with inflammatory bowel disease. A systematic review","volume":"117","author":"L\u00f3pez-Serrano","year":"2025","journal-title":"Rev Esp Enferm Dig"},{"key":"2026061823084165400_jjag085-B20","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1055\/a-0580-7405","article-title":"Linked color imaging reduces the miss rate of neoplastic lesions in the right colon: a randomized tandem colonoscopy study","volume":"50","author":"Paggi","year":"2018","journal-title":"Endoscopy"},{"key":"2026061823084165400_jjag085-B21","doi-asserted-by":"publisher","first-page":"140","DOI":"10.5009\/gnl18276","article-title":"Blue laser imaging, blue light imaging, and linked color imaging for the detection and characterization of colorectal tumors","volume":"13","author":"Yoshida","year":"2019","journal-title":"Gut Liver"},{"key":"2026061823084165400_jjag085-B22","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1111\/den.14915","article-title":"Practical utility of linked color imaging in colonoscopy: updated literature review","volume":"37","author":"Ishibashi","year":"2025","journal-title":"Dig Endosc"},{"key":"2026061823084165400_jjag085-B23","doi-asserted-by":"publisher","first-page":"225","DOI":"10.5946\/ce.2024.072","article-title":"The impact of linked color imaging on adenoma detection rate in colonoscopy: a systematic review and meta-analysis","volume":"58","author":"Zwetkoff","year":"2025","journal-title":"Clin Endosc"},{"key":"2026061823084165400_jjag085-B24","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1111\/den.12992","article-title":"Linked color imaging identified ulcerative colitis-associated colorectal cancer: a case report","volume":"30","author":"Hisamatsu","year":"2018","journal-title":"Dig Endosc"},{"key":"2026061823084165400_jjag085-B25","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1016\/j.dld.2019.03.010","article-title":"A case of screening colonoscopy using linked-color imaging to detect ulcerative colitis-associated colorectal cancer","volume":"51","author":"Kanmura","year":"2019","journal-title":"Dig Liver Dis"},{"key":"2026061823084165400_jjag085-B26","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1053\/j.gastro.2015.01.031","article-title":"SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease","volume":"148","author":"Laine","year":"2015","journal-title":"Gastroenterology"},{"key":"2026061823084165400_jjag085-B27","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1136\/gutjnl-2016-313213","article-title":"Chromoendoscopy versus narrow band imaging in UC: a prospective randomised controlled trial","volume":"67","author":"Bisschops","year":"2018","journal-title":"Gut"},{"key":"2026061823084165400_jjag085-B28","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/ajg.2017.417","article-title":"A randomized trial comparing high definition colonoscopy alone with high definition dye spraying and electronic virtual chromoendoscopy for detection of colonic neoplastic lesions during IBD surveillance colonoscopy","volume":"113","author":"Iacucci","year":"2018","journal-title":"Am J Gastroenterol"},{"key":"2026061823084165400_jjag085-B29","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1093\/ibd\/izy360","article-title":"A randomized crossover trial of conventional vs virtual chromoendoscopy for colitis surveillance: dysplasia detection, feasibility, and patient acceptability (CONVINCE)","volume":"25","author":"Gulati","year":"2019","journal-title":"Inflamm Bowel Dis"},{"key":"2026061823084165400_jjag085-B30","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1093\/ibd\/izaa291","article-title":"Chromoendoscopy with indigo carmine vs virtual chromoendoscopy (iSCAN 1) for neoplasia screening in patients with inflammatory bowel disease: a prospective randomized study","volume":"27","author":"Gonz\u00e1lez-Bernardo","year":"2021","journal-title":"Inflamm Bowel Dis"},{"key":"2026061823084165400_jjag085-B31","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1016\/j.gie.2020.05.044","article-title":"Linked-color imaging versus white-light colonoscopy in an organized colorectal cancer screening program","volume":"92","author":"Paggi","year":"2020","journal-title":"Gastrointest Endosc"},{"key":"2026061823084165400_jjag085-B32","doi-asserted-by":"publisher","first-page":"1708","DOI":"10.1016\/j.cgh.2021.04.004","article-title":"Detection of colorectal neoplasms using linked color imaging: a prospective, randomized, tandem colonoscopy trial","volume":"19","author":"Hasegawa","year":"2021","journal-title":"Clin Gastroenterol Hepatol"},{"key":"2026061823084165400_jjag085-B33","doi-asserted-by":"publisher","first-page":"e335023","DOI":"10.1136\/gutjnl-2025-335023","article-title":"British Society of Gastroenterology guidelines on colorectal surveillance in inflammatory bowel disease","volume":"75","author":"East","year":"2025","journal-title":"Gut"},{"key":"2026061823084165400_jjag085-B34","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1111\/den.15073","article-title":"Adjustment of surveillance intervals for ulcerative colitis-associated neoplasia based on disease duration","volume":"37","author":"Sakakibara","year":"2025","journal-title":"Dig Endosc"},{"key":"2026061823084165400_jjag085-B35","doi-asserted-by":"publisher","first-page":"5784","DOI":"10.3390\/cancers15245754","article-title":"Treat-to-target and regular surveillance of inflammatory bowel disease are associated with low incidence and early-stage detection of malignancies: a retrospective cohort study","volume":"15","author":"Parigi","year":"2023","journal-title":"Cancers (Basel)"},{"key":"2026061823084165400_jjag085-B36","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1111\/apt.12651","article-title":"Systematic review with meta-analysis: the declining risk of colorectal cancer in ulcerative colitis","volume":"39","author":"Casta\u00f1o-Milla","year":"2014","journal-title":"Aliment Pharmacol Ther"}],"container-title":["Journal of Crohn's and Colitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ecco-jcc\/article-pdf\/20\/6\/jjag085\/68556478\/jjag085.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ecco-jcc\/article-pdf\/20\/6\/jjag085\/68556478\/jjag085.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T03:08:51Z","timestamp":1781838531000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ecco-jcc\/article\/doi\/10.1093\/ecco-jcc\/jjag085\/8711423"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6,7]]}},"URL":"https:\/\/doi.org\/10.1093\/ecco-jcc\/jjag085","relation":{},"ISSN":["1873-9946","1876-4479"],"issn-type":[{"value":"1873-9946","type":"print"},{"value":"1876-4479","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,6]]},"published":{"date-parts":[[2026,6]]},"article-number":"jjag085"}}