{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T04:55:45Z","timestamp":1791780945962,"version":"4.3.4"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T00:00:00Z","timestamp":1602633600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,3,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims\u2003<\/jats:title><jats:p>Cardiogenic shock (CS) is associated with high mortality. Current guidelines strongly recommend centralizing the care of these patients in high-complexity centres. We described the hospitalization-related economic cost and its main determinants in patients with CS in a high-complexity reference centre.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results\u2003<\/jats:title><jats:p>This is a single-centre, retrospective study. All patients with CS (2015\u201317) were included. Hospitalization-related cost per patient was calculated by analytical accountability method, including hospital stay-related expenditures, interventions, and consumption of devices. Expenditure was expressed in 2018 euros. All-cause mortality during follow-up was registered. Ratio of cost per life-year gained (LYG) was also calculated. A total of 230 patients were included, with mean age of 63 years. In-hospital mortality was 88\/230 (38.3%). Hospital stay was longer in patients surviving after the admission (21.7 vs. 7.5 days, P\u2009&amp;lt;\u20090.001). Total economic cost for the overall cohort was 3\u00a0947\u00a0118\u20ac (mean\/patient 17\u00a0161\u20ac). Most of this cost was attributable to hospital stay (81.1%). The rest of the expenditure was due to in-hospital procedures (13.1%) and the use of devices (5.8%). Most of hospital stay-related costs (79.8%) were due to Critical Care Unit stay. Mean follow-up was 651 days. Total LYG was 409.77 years for the whole series. The observed ratio of cost per LYG was 9632.52 \u20ac\/LYG.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions\u2003<\/jats:title><jats:p>Management of CS in a reference centre is associated to a significant economic cost, but with a low ratio of cost per LYG. Most of this cost is attributable to hospital stay, specifically in critical care units.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ehjacc\/zuaa003","type":"journal-article","created":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T04:14:14Z","timestamp":1609474454000},"page":"50-53","source":"Crossref","is-referenced-by-count":13,"title":["Hospitalization-related economic impact of patients with cardiogenic shock in a high-complexity reference centre"],"prefix":"10.1093","volume":"10","author":[{"given":"Elena","family":"Collado","sequence":"first","affiliation":[{"name":"Cardiology Department, Bellvitge University Hospital-IDIBELL, L\u2019Hospitalet de Llobregat, Carrer de la Feixa Llarga s\/n, Barcelona 08907, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5095-584X","authenticated-orcid":false,"given":"Daniele","family":"Luiso","sequence":"additional","affiliation":[{"name":"Cardiology Department, Bellvitge University Hospital-IDIBELL, L\u2019Hospitalet de Llobregat, Carrer de la Feixa Llarga s\/n, Barcelona 08907, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Ariza-Sol\u00e9","sequence":"additional","affiliation":[{"name":"Cardiology Department, Bellvitge University Hospital-IDIBELL, L\u2019Hospitalet de Llobregat, Carrer de la Feixa Llarga s\/n, Barcelona 08907, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Lorente","sequence":"additional","affiliation":[{"name":"Cardiology Department, Bellvitge University Hospital-IDIBELL, L\u2019Hospitalet de Llobregat, Carrer de la Feixa Llarga s\/n, Barcelona 08907, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Carlos","family":"S\u00e1nchez-Salado","sequence":"additional","affiliation":[{"name":"Cardiology Department, Bellvitge University Hospital-IDIBELL, L\u2019Hospitalet de Llobregat, Carrer de la Feixa Llarga s\/n, Barcelona 08907, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramon","family":"Moreno","sequence":"additional","affiliation":[{"name":"Cardiology Department, Bellvitge University Hospital-IDIBELL, L\u2019Hospitalet de Llobregat, Carrer de la Feixa Llarga s\/n, Barcelona 08907, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Alsina","sequence":"additional","affiliation":[{"name":"Cardiology Department, Bellvitge University Hospital-IDIBELL, L\u2019Hospitalet de Llobregat, Carrer de la Feixa Llarga s\/n, Barcelona 08907, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Tapia","sequence":"additional","affiliation":[{"name":"Cardiology Department, Bellvitge University Hospital-IDIBELL, L\u2019Hospitalet de Llobregat, Carrer de la Feixa Llarga s\/n, Barcelona 08907, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Gonz\u00e1lez-Costello","sequence":"additional","affiliation":[{"name":"Cardiology Department, Bellvitge University Hospital-IDIBELL, L\u2019Hospitalet de Llobregat, Carrer de la Feixa Llarga s\/n, Barcelona 08907, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Comin-Colet","sequence":"additional","affiliation":[{"name":"Cardiology Department, Bellvitge University Hospital-IDIBELL, L\u2019Hospitalet de Llobregat, Carrer de la Feixa Llarga s\/n, Barcelona 08907, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,10,14]]},"reference":[{"key":"2021072111394638300_zuaa003-B1","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.113.000590","article-title":"Trends in incidence, management, and outcomes of cardiogenic shock complicating ST-elevation myocardial infarction in the United 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