{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T08:21:23Z","timestamp":1759566083756,"version":"3.37.3"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T00:00:00Z","timestamp":1676937600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"University Medical Centre Ljubljana"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,17]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Because re-establishment of spontaneous circulation (ROSC) in patients with cardiac arrest is frequently not achieved by conventional cardiopulmonary resuscitation (C-CPR), selected patients may undergo resuscitation with extracorporeal membrane oxygenation (E-CPR). We compared angiographic features and percutaneous coronary intervention (PCI) between patients undergoing E-CPR and those with ROSC after C-CPR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>Forty-nine consecutive E-CPR patients undergoing immediate coronary angiography admitted between August 2013 and August 2022 were matched to 49 patients with ROSC after C-CPR. Multivessel disease (69.4% vs. 34.7%; P = 0.001), \u2265 50% unprotected left main (ULM) stenosis (18.4% vs. 4.1%; P = 0.025), and \u22651 chronic total occlusion (CTO) (28.6% vs. 10.2%; P = 0.021) were more often documented in E-CPR group. There was no significant differences in the incidence, features, and distribution of acute culprit lesion which was present in &amp;gt;90%. Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) (27.6 vs. 13.4; P = 0.002) and GENSINI (86.2 vs. 46.0; P = 0.001) scores were increased in E-CPR group. Optimal cut-off predicting E-CPR was 19.75 for SYNTAX (sensitivity 74%, specificity 87%) and 60.50 (sensitivity 69%, specificity 75%) for GENSINI score. More lesions were treated (1.3 vs. 1.1 lesions\/patient; P = 0.002) and stents implanted (2.0 vs. 1.3\/patient; P &amp;lt; 0.001) in E-CPR group. Final TIMI three flow was comparable (88.6% vs. 95.7%; P = 0.196) but residual SYNTAX (13.6 vs. 3.1; P &amp;lt; 0.001) and GENSINI (36.7 vs. 10.9; P &amp;lt; 0.001) scores remained increased in E-CPR group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Extracorporeal membrane oxygenation patients have more multivessel disease, ULM stenosis, and CTO but similar incidence, features, and distribution of acute culprit lesion. Despite more complex PCI, revascularization is less complete.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ehjacc\/zuad012","type":"journal-article","created":{"date-parts":[[2023,2,20]],"date-time":"2023-02-20T14:53:12Z","timestamp":1676904792000},"page":"260-266","source":"Crossref","is-referenced-by-count":0,"title":["Coronary disease in refractory cardiac arrest undergoing resuscitation with extracorporeal membrane oxygenation"],"prefix":"10.1093","volume":"12","author":[{"given":"Danilo","family":"Franco","sequence":"first","affiliation":[{"name":"Center for Intensive Internal Medicine, University Medical Center , Zaloska 7, 1000 Ljubljana , Slovenia"},{"name":"Department of Advance Biomedical Sciences, Federico II University , Via Pansini 5, 80131 Naples , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomaz","family":"Goslar","sequence":"additional","affiliation":[{"name":"Center for Intensive Internal Medicine, University Medical Center , Zaloska 7, 1000 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