{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T01:11:05Z","timestamp":1767921065984,"version":"3.49.0"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T00:00:00Z","timestamp":1686268800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100009664","name":"Spanish Society of Cardiology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009664","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Instituto para la Mejor\u00eda de la Atenci\u00f3n Sanitaria"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Cardiogenic shock (CS) is associated with high mortality. The purpose of this study was to assess the impact of hospital structure-related variables on mortality in patients with CS treated at percutaneous and surgical revascularization capable centres (psRCC) from a large nationwide registry.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Retrospective observational study including consecutive patients with main or secondary diagnosis of CS and ST elevation myocardial infarction (STEMI). Patients discharged from Spanish National Healthcare System psRCC were included (2016\u201320). The association between the volume of CS cases attended by each centre, availability of intensive cardiac care unit (ICCU) and heart transplantation (HT) programmes, and in-hospital mortality was assessed by multilevel logistic regression models. The study population consisted of 3074 CS-STEMI episodes, of whom 1759 (57.2%) occurred in 26 centres with ICCU. A total of 17\/44 hospitals (38.6%) were high-volume centres, and 19\/44 (43%) centres had HT programmes availability. Treatment at HT centres was not associated with a lower mortality (P = 0.121). Both high volume of cases and ICCU showed a trend to an association with lower mortality in the adjusted model [odds ratio (OR): 0.87 and 0.88, respectively]. The interaction between both variables was significantly protective (OR 0.72; P = 0.024). After propensity score matching, mortality was lower in high-volume hospitals with ICCU (OR 0.79; P = 0.007).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Most CS-STEMI patients were attended at psRCC with high volume of cases and ICCU available. The combination of high volume and ICCU availability showed the lowest mortality. These data should be taken into account when designing regional networks for CS management.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjacc\/zuad061","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T05:51:29Z","timestamp":1686203489000},"page":"422-429","source":"Crossref","is-referenced-by-count":5,"title":["Impact of annual volume of cases and intensive cardiac care unit availability on mortality of patients with acute myocardial infarction-related cardiogenic shock treated at revascularization capable centres"],"prefix":"10.1093","volume":"12","author":[{"given":"M Isabel","family":"Barrionuevo-S\u00e1nchez","sequence":"first","affiliation":[{"name":"Bellvitge University Hospital, L\u2019Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"},{"name":"Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7194-8419","authenticated-orcid":false,"given":"Ana","family":"Viana-Tejedor","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico San Carlos , Prof Martin Lagos Street, 28040 Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0819-6656","authenticated-orcid":false,"given":"Albert","family":"Ariza-Sol\u00e9","sequence":"additional","affiliation":[{"name":"Bellvitge University Hospital, L\u2019Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"},{"name":"Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00e1yade","family":"del Prado","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Instituto para la Mejora de la Asistencia Sanitaria, Beatriz de Bobadilla street 13, Bj , 28008 Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicol\u00e1s","family":"Rosillo","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Instituto para la Mejora de la Asistencia Sanitaria, Beatriz de Bobadilla street 13, Bj , 28008 Madrid , Spain"},{"name":"Hospital Universitario 12 de Octubre , C\u00f3rdoba Avenue, 28041 Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Carlos","family":"S\u00e1nchez-Salado","sequence":"additional","affiliation":[{"name":"Bellvitge University Hospital, L\u2019Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"},{"name":"Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vict\u00f2ria","family":"Lorente","sequence":"additional","affiliation":[{"name":"Bellvitge University Hospital, L\u2019Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"},{"name":"Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Jorge-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Cardiology Department, Hospital Universitario de Canarias , Carretera Ofra, La Laguna, 38320 Santa Cruz de Tenerife , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Javier","family":"Noriega","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico San Carlos , Prof Martin Lagos Street, 28040 Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Ferrera","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico San Carlos , Prof Martin Lagos Street, 28040 Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oriol","family":"Alegre","sequence":"additional","affiliation":[{"name":"Bellvitge University Hospital, L\u2019Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"},{"name":"Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isaac","family":"Lla\u00f3","sequence":"additional","affiliation":[{"name":"Bellvitge University Hospital, L\u2019Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"},{"name":"Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Luis","family":"Bernal","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Instituto para la Mejora de la Asistencia Sanitaria, Beatriz de Bobadilla street 13, Bj , 28008 Madrid , Spain"},{"name":"Hospital Universitario 12 de Octubre , C\u00f3rdoba Avenue, 28041 Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Triguero","sequence":"additional","affiliation":[{"name":"Bellvitge University Hospital, L\u2019Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"},{"name":"Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Fern\u00e1ndez-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Instituto para la Mejora de la Asistencia Sanitaria, Beatriz de Bobadilla street 13, Bj , 28008 Madrid , Spain"},{"name":"Servicio de Medicina Preventiva, \u00c1rea Sanitaria de Santiago y Barbanza, Instituto de Investigaciones Sanitarias de Santiago , Tr Da Choupama, 15706 Santiago de Compostela (A Coru\u00f1a) , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Gonz\u00e1lez-Costello","sequence":"additional","affiliation":[{"name":"Bellvitge University Hospital, L\u2019Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"},{"name":"Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Enfermedades Cardiovasculares CIBER-CV, Instituto de Salud Carlos III, Melchor Fernandez Almagro Stret, 3 , 28029 Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Marcos","sequence":"additional","affiliation":[{"name":"Bellvitge University Hospital, L\u2019Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"},{"name":"Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"de la Cuerda","sequence":"additional","affiliation":[{"name":"Bellvitge University Hospital, L\u2019Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"},{"name":"Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jes\u00fas","family":"Carmona","sequence":"additional","affiliation":[{"name":"Bellvitge University Hospital, L\u2019Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"},{"name":"Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angel","family":"Cequier","sequence":"additional","affiliation":[{"name":"Bellvitge University Hospital, L\u2019Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Fern\u00e1ndez-Ortiz","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico San Carlos , Prof Martin Lagos Street, 28040 Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juli\u00e1n","family":"P\u00e9rez-Villacast\u00edn","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico San Carlos , Prof Martin Lagos Street, 28040 Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8780-720X","authenticated-orcid":false,"given":"Josep","family":"Comin-Colet","sequence":"additional","affiliation":[{"name":"Bellvitge University Hospital, L\u2019Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"},{"name":"Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat , Feixa Llarga s\/n, 08907 Barcelona , Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Enfermedades Cardiovasculares CIBER-CV, Instituto de Salud Carlos III, Melchor Fernandez Almagro Stret, 3 , 28029 Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Javier","family":"Elola","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Instituto para la Mejora de la Asistencia Sanitaria, Beatriz de Bobadilla street 13, Bj , 28008 Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,6,9]]},"reference":[{"key":"2023070718441674100_zuad061-B1","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1056\/NEJM199908263410901","article-title":"Early revascularization in acute myocardial infarction complicated by cardiogenic shock. SHOCK investigators. Should we emergently revascularize occluded coronaries for cardiogenic shock","volume":"341","author":"Hochman","year":"1999","journal-title":"N Engl J Med"},{"key":"2023070718441674100_zuad061-B2","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1016\/j.jacc.2008.05.065","article-title":"A randomized clinical trial to evaluate the safety and efficacy of a percutaneous left ventricular assist device versus intra-aortic balloon pumping for treatment of cardiogenic shock caused by myocardial infarction","volume":"52","author":"Seyfarth","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"2023070718441674100_zuad061-B3","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.jacc.2016.10.022","article-title":"Percutaneous mechanical circulatory support versus intra-aortic balloon pump in cardiogenic shock after acute myocardial infarction","volume":"69","author":"Ouweneel","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2023070718441674100_zuad061-B4","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.114.001462","article-title":"Effect of cardiogenic shock hospital volume on mortality in patients with cardiogenic shock","volume":"4","author":"Shaefi","year":"2015","journal-title":"J Am Heart Assoc"},{"key":"2023070718441674100_zuad061-B5","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.ijcard.2017.06.082","article-title":"Impact of a cardiac intensivist on mortality in patients with cardiogenic shock","volume":"244","author":"Na","year":"2017","journal-title":"Int J Cardiol"},{"key":"2023070718441674100_zuad061-B6","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s12874-015-0013-2","article-title":"Positive predictive value of international classification of diseases, 10th revision, diagnosis codes for cardiogenic, hypovolemic, and septic shock in the Danish National Patient Registry","volume":"15","author":"Lauridsen","year":"2015","journal-title":"BMC Med Res Methodol"},{"key":"2023070718441674100_zuad061-B7","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","article-title":"2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"42","author":"McDonagh","year":"2021","journal-title":"Eur Heart J"},{"key":"2023070718441674100_zuad061-B8","author":"Registro de altas de hospitalizaci\u00f3n: CMBD del Sistema Nacional de Salud"},{"key":"2023070718441674100_zuad061-B9","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.recesp.2015.07.018","article-title":"The healthcare of patients with acute and critical heart disease. Position of the Spanish Society of Cardiology","volume":"69","author":"Worner","year":"2016","journal-title":"Rev Esp Cardiol"},{"key":"2023070718441674100_zuad061-B10","author":"2020 Condition-Specific Measures Updates and Specifications Report Hospital-Level 30-Day Risk-Standardized Mortality Measures"},{"key":"2023070718441674100_zuad061-B11","first-page":"93","article-title":"Principal inpatient diagnostic cost group model for Medicare risk adjustment","volume":"21","author":"Pope","year":"2000","journal-title":"Health Care Financ Rev"},{"key":"2023070718441674100_zuad061-B12","author":"Pope"},{"key":"2023070718441674100_zuad061-B13","doi-asserted-by":"crossref","first-page":"385","DOI":"10.2307\/2983325","article-title":"League tables and their limitations: statistical aspects of institutional performance","volume":"159","author":"Goldstein","year":"1996","journal-title":"J Royal Stat Soc Ser A"},{"key":"2023070718441674100_zuad061-B14","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1080\/01621459.1997.10474036","article-title":"Statistical methods for profiling providers of medical care: issues and applications","volume":"92","author":"Normand","year":"1997","journal-title":"J Am Stat Assoc"},{"key":"2023070718441674100_zuad061-B15","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1016\/S0003-4975(01)03222-2","article-title":"Cardiac surgery report cards: comprehensive review and statistical critique","volume":"72","author":"Shahian","year":"2001","journal-title":"Ann Thorac Surg"},{"key":"2023070718441674100_zuad061-B16","author":"Mart\u00ednez-Sell\u00e9s"},{"key":"2023070718441674100_zuad061-B17","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.recesp.2020.01.019","article-title":"Initial outcomes of a multidisciplinary network for the care of patients with cardiogenic shock","volume":"74","author":"Hern\u00e1ndez-P\u00e9rez","year":"2021","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"key":"2023070718441674100_zuad061-B18","first-page":"879","article-title":"A standardized and comprehensive approach to the management of cardiogenic shock","volume":"8","author":"Tehrani","year":"2020","journal-title":"JACC: Heart Fail"},{"key":"2023070718441674100_zuad061-B19","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.1016\/j.jacc.2018.07.074","article-title":"Cardiac shock care centers: JACC review topic of the week","volume":"72","author":"Rab","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"2023070718441674100_zuad061-B20","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1002\/ehf2.13180","article-title":"Cardiogenic shock teams and centres: a contemporary review of multidisciplinary care for cardiogenic shock","volume":"8","author":"Moghaddam","year":"2021","journal-title":"ESC Heart Fail"},{"key":"2023070718441674100_zuad061-B21","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1002\/ejhf.1922","article-title":"Epidemiology, pathophysiology and contemporary management of cardiogenic shock\u2014a position statement from the heart failure association of the European Society of Cardiology","volume":"22","author":"Chioncel","year":"2020","journal-title":"Eur J Heart Fail"},{"key":"2023070718441674100_zuad061-B22","first-page":"546","article-title":"Trends in cardiogenic shock management and prognostic impact of type of treating center","volume":"73","author":"S\u00e1nchez-Salado","year":"2020","journal-title":"RevEspCardiol"},{"key":"2023070718441674100_zuad061-B23","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.120.021150","article-title":"Impact of center volume on outcomes in myocardial infarction complicated by cardiogenic shock: a CULPRIT-SHOCK substudy","volume":"10","author":"Schrage","year":"2021","journal-title":"J Am Heart Assoc"},{"key":"2023070718441674100_zuad061-B24","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.jacc.2021.07.044","article-title":"Management and outcomes of cardiogenic shock in cardiac ICUs with versus without shock teams","volume":"78","author":"Papolos","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"2023070718441674100_zuad061-B25","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1161\/CIRCULATIONAHA.119.040654","article-title":"Shock team approach in refractory cardiogenic shock requiring short-term mechanical circulatory support: a proof of concept","volume":"140","author":"Taleb","year":"2019","journal-title":"Circulation"},{"key":"2023070718441674100_zuad061-B26","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1093\/ehjacc\/zuaa003","article-title":"Hospitalization-related economic impact of patients with cardiogenic shock in a high-complexity reference centre","volume":"10","author":"Collado","year":"2021","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"2023070718441674100_zuad061-B27","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1161\/CIRCULATIONAHA.105.611186","article-title":"An administrative claims model suitable for profiling hospital performance based on 30-day mortality rates among patients with an acute myocardial infarction","volume":"113","author":"Krumholz","year":"2006","journal-title":"Circulation"},{"key":"2023070718441674100_zuad061-B28","doi-asserted-by":"crossref","first-page":"E1067","DOI":"10.1503\/cmaj.110400","article-title":"Incidence of potentially avoidable urgent readmissions and their relation to all-cause urgent readmissions","volume":"183","author":"van Walraven","year":"2011","journal-title":"CMAJ"}],"container-title":["European Heart Journal: Acute Cardiovascular Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjacc\/advance-article-pdf\/doi\/10.1093\/ehjacc\/zuad061\/50680775\/zuad061.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjacc\/article-pdf\/12\/7\/422\/50839894\/zuad061.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjacc\/article-pdf\/12\/7\/422\/50839894\/zuad061.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T18:45:30Z","timestamp":1688755530000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjacc\/article\/12\/7\/422\/7192937"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,9]]},"references-count":28,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2023,6,9]]},"published-print":{"date-parts":[[2023,7,7]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjacc\/zuad061","relation":{},"ISSN":["2048-8726","2048-8734"],"issn-type":[{"value":"2048-8726","type":"print"},{"value":"2048-8734","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,7]]},"published":{"date-parts":[[2023,6,9]]}}}